Interferon Alfa-2b duro

Qanacsan

• Interferon alfa-2b duro ayaa loo isticmaalaa
• Haddii aad leedahay:
• Kahor intaadan helin duritaanka alfa-2b ee interferon,
• Isku-darka Interferon alfa-2b wuxuu sababi karaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama mid ama kuwa ku taxan DIGNIIN MUHIIM AH ama qaybaha taxadarka khaaska ah, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo deg deg ah:

Isku-darka Interferon alfa-2b wuxuu sababi karaa ama uga sii dari karaa xaaladaha soo socda oo noqon kara kuwo halis ah ama nafta halis geliya: infekshannada; jirro maskaxeed, oo ay ku jiraan niyad-jabka, dhibaatooyinka niyadda iyo dabeecadda, ama fikradaha waxyeellada ama naftaada ama dadka kale; cilladaha ischemic (xaaladaha ay ku yar tahay bixinta jirka ee meel jirka ka mid ah) sida angina (laab xanuun) ama wadne qabad; iyo cilladaha isdifaaca jirka (xaaladaha nidaamka difaaca jirka uu ku weeraro hal ama in kabadan oo jirka ah oo saameyn ku yeelan kara dhiigga, kalagoysyada, kilyaha, beerka, sambabada, murqaha, maqaarka, ama qanjirka 'thyroid'). U sheeg dhakhtarkaaga haddii aad caabuq qabto; ama haddii aad qabto ama aad waligaa qabtid cudur isdifaaca jirka, cudurka psoriasis (cudurka maqaarka ee casaanka, jajabka maqaarku ku sameysmaan meelaha jirka qaarkood), lupus erythematosus systemic (SLE ama lupus); qaybaha jirka), sarcoidosis (xaalad kuuskuus yar oo unugyada difaaca ahi ku samaysmaan xubno kala duwan sida sambabada, indhaha, maqaarka, iyo wadnaha oo farageliya shaqada xubnahan), ama rheumatoid arthritis (RA; xaalad taas oo jidhku ku weerarayo kala-goysyadiisa, oo keenaya xanuun, barar, iyo shaqo-la'aan); kansarka; colitis (caabuq ku dhaca xiidmaha); sonkorowga; wadne qabad; dhiig kar; heerarka triglyceride ee sarreeya (dufanka la xiriira kolestaroolka); HIV (fayraska difaaca jirka ee bini aadamka) ama AIDS (cudurka difaaca jirka oo la helay); garaaca wadnaha oo aan joogto ahayn; cudurada maskaxda oo ay ka mid yihiin niyad jab, walwal, ama ka fikirida ama isku dayida naftaada; ama wadnaha, kilyaha, xammeetida, ama cudurka qanjirka 'thyroid'.

Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba wac dhakhtarkaaga: shuban dhiig leh ama saxaro; qandho, dhaxan, qufac xaako (xabka), cuna xanuun, ama calaamadaha kale ee infekshanka; kaadi badan ama xanuun, xabad xanuun; garaaca wadnaha oo aan joogto ahayn; isbeddelada niyaddaada ama dhaqankaaga; niyad jab; inaad bilawdo inaad mar labaad isticmaasho daroogada waddooyinka ama aalkolada haddii aad waagii hore aad u isticmaali jirtay; xanaaq (si fudud u xanaaqa); fikirka ah inaad is disho ama aad dhaawacdo naftaada; dabeecad dagaal ama rabshad; neefsashada oo ku adkaata; xabad xanuun; isbeddelka socodka ama hadalka; hoos u dhaca xoog ama daciifnimo dhinac jirkaaga ah; aragga oo xumaada ama arag la'aan; calool xanuun daran; dhiigbax ama nabar aan caadi ahayn; kaadi midab madow; saxaro midab khafiif ah leh; ama ka sii daraya cudur isdifaaca jirka.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa baaritaano gaar ah si loo hubiyo jawaabta jirkaaga ee interferon alfa-2b.

Dhakhtarkaaga ama farmashiistahaaga ayaa ku siin doona warqada macluumaadka bukaanka soo-saaraha (Tilmaamaha Daawada) marka aad bilowdo daaweynta interferon alfa-2b iyo mar kasta oo aad dib u buuxiso dawadaada. Si taxaddar leh u akhri macluumaadka oo weydii dhakhtarkaaga ama farmashiistaha haddii aad wax su'aalo ah qabtid. Waxa kale oo aad booqan kartaa websaydhka Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ama websaydhka soosaaraha si aad u hesho Hagaha Daawada.

Isku-darka Interferon alfa-2b waxaa loo isticmaalaa in lagu daaweeyo xaalado dhowr ah.

Interferon alfa-2b duro ayaa loo isticmaalaa

• keligiis ama lagu daro ribavirin (Copegus, Rebetol, Ribasphere) si loogu daaweeyo infekshinka cagaarshowga C (ee muddada dheer) (bararka beerka ee uu sababo fayras) dadka muujinaya calaamadaha dhaawaca beerka,
• si loo daaweeyo infekshinka cagaarshow B ee joogtada ah (bararka beerka ee uu sababo fayras) dadka muujiya calaamadaha dhaawaca beerka,
• si loo daaweeyo kansarka unugyada unugyada dhiigga (kansarka unugyada dhiigga cad),
• daaweynta burooyinka xubnaha taranka,
• si loo daaweeyo Kaposi sarcoma (nooc ka mid ah kansarka keena unugyada aan caadiga ahayn inay ku koraan qeybaha kala duwan ee jirka) ee la xiriira cilladda difaaca jirka ee la helay (AIDS),
• in lagu daaweeyo melanoma xun (kansar ka bilaabma unugyada maqaarka qaarkood) dad gaar ah oo qalliin lagu sameeyay si looga saaro kansarka,
• oo ay weheliso daawo kale oo lagu daaweeyo qanjirka 'non-Hodgkin's lymphoma' (NHL; si tartiib tartiib ah u koraya kansarka dhiigga).

Interferon alfa-2b waxay ku jirtaa nooc dawooyin ah oo loo yaqaan immunomodulators. Interferon alfa-2b wuxuu ka shaqeeyaa daaweynta fayraska cagaarshowga C (HCV) iyo fayraska cagaarshowga B (HBV) iyadoo la yareynayo qaddarka fayraska ee jirka ku jira. Interferon alfa-2b ma daaweyn karo cagaarshowga B ama cagaarshowga C ama wuxuu kaa hor istaagi karaa inaad ku dhacdo dhibaatooyin ka yimaada cuduradan sida cirrhosis (nabar) beerka, beerka oo shaqeynaya, ama kansarka beerka. Sidoo kale kama hortagi karto faafitaanka cagaarshowga B ama C dadka kale. Si dhab ah looma oga sida interferon alfa-2b ugu shaqeeyo daweynta kansarka ama burooyinka xubnaha taranka.

Interferon alfa-2b waxay u timaadaa sidii budo ah weel si ay ugu dhex qasto dareeraha iyo xalka in lagu durto si ka hooseysa (maqaarka hoostiisa), intramuscularly (muruq), xidid (xididka), ama xididada (dhaawac ah ). Waxaa ugufiican in lagugu duro daawada isku wakhti maalinti ah maalmaha lagugu duray, badiyaa galabtii ama galabtii.

Haddii aad leedahay:

• HCV, ku dur dur daawada mid ka mid ah qaab hoosaad ah ama murqaha ah seddex jeer usbuucii.
• HBV, ku dur dur daawada si hoose ama intramuscular seddex jeer usbuucii sida caadiga ah 16 toddobaad.
• unugyada leukemia ee timaha leh, ku dur dur dawada midkood muruq ahaan ama hoosaad ahaan 3 jeer usbuucii ilaa 6 bilood.
• melanoma malignant, ku dur irbadda dawada xididka 5 maalmood oo isku xigta 4 todobaad, ka dibna subcutaneous seddex jeer usbuucii 48 toddobaad.
• melanoma follicular, ku dur dawada si khafiif ah seddex jeer usbuucii usbuuc ilaa 18 bilood.
• burooyinka xubinta taranka, ku dur irbadda dawada xididdada dhiigga saddex jeer usbuucii maalmaha kala duwan muddo 3 toddobaad ah, ka dib daaweyn ayaa laga yaabaa inay sii socoto ilaa 16 toddobaad.
• Kaposi’s sarcoma, ku dur dawada midkood hoos ama si muruqa ah seddex jeer usbuucii usbuucyada 16.

Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. U isticmaal duriinka interferon alfa-2b sida saxda ee lagu faray. Ha u isticmaalin wax ka yar ama ka yar dawadan ama ha u isticmaalin marar badan ama muddo ka badan intii dhakhtarku kuu qoray.

Dhakhtarkaaga ayaa laga yaabaa inuu yareeyo qiyaastaada haddii aad isku aragto waxyeelo daran oo daawada ah. Hubso inaad u sheegto dhakhtarkaaga sida aad dareemeyso inta lagu jiro daaweyntaada oo weydii dhakhtarkaaga ama farmashiistaha haddii aad su'aalo ka qabtid xaddiga daawada ay tahay inaad isticmaasho.

Waxaad ka heli doontaa qiyaastaada ugu horreysa ee interferon alfa-2b xafiiska dhakhtarkaaga. Intaas kadib, waxaad isku duri kartaa interferon alfa-2b naftaada ama saaxiib ama qaraabo ayaa ku siin kara cirbadaha. Kahor intaadan isticmaalin interferon alfa-2b markii ugu horreysay, adiga ama qofka irbadda bixin doona waa inaad u aqriso macluumaadka soo-saaraha bukaanka la socda. Weydii dhakhtarkaaga ama farmashiistaha inuu ku tuso adiga ama qofka ku duraya daawada sida loo isku duro. Haddii qof kale kugu durayo daawada, hubi inuu isagu ama iyadu ogyahay sida looga fogaado irbadaha shilalka ee lama filaan ah.

Haddii aad isku durayso daawadan si ka hooseysa, ku dur interferon alfa-2b meel kasta oo ka mid ah aagga calooshaada, gacmaha kore, ama bowdyahaaga, marka laga reebo agagaarka dhexdaada ama xudduntaada (badhanka caloosha). Ha ku durin daawadaada maqaar cuncun leh, nabar leh, casaan, cudur, ama nabar ah.

Haddii aad isku dureyso daawadan si murqaha ah, ku dur interferon alfa-2b gacmahaaga kore, bowdyahaaga, ama aagga kore ee badhida. Ha isticmaalin isla barta laba jeer oo isku xigta.Ha ku durin daawadaada maqaar cuncun leh, nabar leh, casaan, cudur, ama nabar ah.

Haddii aad isku dureyso daawadan lagaa siidaayo, si toos ah ugu dur bartamaha salka wart.

Marna dib ha u isticmaalin irbadaha, irbadaha, ama fijaannada 'interferon alfa-2b'. Ku tuur cirbadaha iyo irbadaha la isticmaalay weel u adkaysata daloolka, isla markaana ku tuur dhalooyinka ku jira dawooyinka la isticmaalay qashinka. Kala hadal dhakhtarkaaga ama farmashiistaha sida loo tuuro weelka daloolka u adkaysta.

Kahor intaadan isticmaalin interferon alfa-2b, fiiri xalka dhalada ku jirta. Daawada waa inay noqotaa mid cad oo ka madax banaan jajabyada sabayn. Hubi weelka si aad u hubiso inaysan jirin wax daadad ah oo hubi taariikhda dhicitaanka. Ha isticmaalin xalka haddii uu dhacay, daruuro leh, ay ku jiraan qaybo, ama ku jiro weel daadanaya.

Waa inaad isku qastaa kaliya hal dhalo oo ah interferon alfa-2b markiiba. Waxaa ugu fiican in la isku qaso daawada isla markiiba ka hor intaadan qorsheynin inaad isku durto. Si kastaba ha noqotee, waad isku qasan kartaa daawada kahor, waxaad ku keydin kartaa qaboojiyaha, waxaadna isticmaali kartaa 24 saac gudahood. Hubso inaad ka qaadato daawooyinka qaboojiyaha oo u oggolow inuu yimaado heerkulka qolka kahor intaadan isku durin.

Dhakhtarkaaga ama farmashiistahaaga ayaa ku siin doona warqada macluumaadka bukaanka soo-saaraha (Tilmaamaha Daawada) marka aad bilowdo daaweynta interferon alfa-2b iyo mar kasta oo aad dib u buuxiso dawadaada. Si taxaddar leh u akhri macluumaadka oo weydii dhakhtarkaaga ama farmashiistaha haddii aad wax su'aalo ah qabtid.

Interferon alfa-2b sidoo kale mararka qaarkood waxaa loo isticmaalaa in lagu daaweeyo fayraska cagaarshowga D (HDV, bararka beerka ee uu sababo fayras), kansarka unugyada aasaasiga ah (nooc ka mid ah kansarka maqaarka), unugyada maqaarka ee 'T-cell lymphomas' (CTCL, nooca kansarka maqaarka) ), iyo kansarka kalyaha. Kala hadal dhakhtarkaaga khataraha aad u leedahay isticmaalka dawadan xaaladaada.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan helin duritaanka alfa-2b ee interferon,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay cirbadda interferon alfa-2b, dawooyinka kale ee interferon alfa oo ay ku jiraan PEG-interferon alfa-2b (PEG-Intron) iyo PEG-interferon alfa-2a (Pegasys), dawooyin kale oo kasta, albumin, ama mid ka mid ah maaddooyinka kale ee ku jira duritaanka alfa-2b interferon. Weydii farmashiistahaaga ama ka hubi Hagaha Daawada liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: telbivudine (Tyzeka), theophylline (Elixophyllin, Theo-24, Theochron), ama zidovudine (Retrovir, Combivir, Trizivir). Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
• u sheeg dhakhtarkaaga haddii aad qabtid cudur daran oo beerka ah ama hepatitis autoimmune (xaalad ay unugyada nidaamka difaaca jirka ku weeraraan beerka). Dhakhtarkaagu wuxuu kuu sheegi doonaa inaadan isticmaalin isku-darka interferon alfa-2b.
• u sheeg dhakhtarkaaga ama farmashiistaha haddii aad waligaa ku beddeshay xubin (qalliin lagu beddelayo xubin jirka ku jirta) oo aad qaadanaysid daawooyin lagu cabudhinayo nidaamkaaga difaaca. Sidoo kale u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa yeelatay mid ka mid ah xaaladaha lagu xusay qaybta DIGNIINTA MUHIIMKA ah ama mid ka mid ah kuwan soo socda: dhiig-yaraan (unugyada dhiigga cas oo hooseeya) ama unugyada dhiigga cad oo hooseeya, dhibaatooyinka dhiigbaxa ama xinjirowga dhiigga oo ay ku jiraan dhiig-baxa sambabada PE; xinjirowga dhiigga ee sanbabada), cudur sambabaha ah sida oof wareen, dhiig karka sambabaha (PAH, dhiig karka ku dhaca xididdada dhiigga u qaada sambabada, taasoo keenta neef qabad, wareer, iyo daal) (COPD; koox cudurro ah oo saameeya sambabaha iyo marinnada hawada), ama dhibaatooyinka indhaha.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanaysid cirbadda interferon alfa-2b, wac dhakhtarkaaga.
• haddii aad qalliin sameyneyso, oo ay ku jiraan qalliinka ilkaha, u sheeg dhakhtarka ama dhakhtarka ilkaha inaad heleyso interferon alfa-2b.
• waa inaad ogaataa inaad yeelan karto calaamado hargab oo kale ah sida madax xanuun, dhidid, murqo xanuun, iyo daal ka dib marka lagaa duro. Dhakhtarkaagu wuxuu kuu sheegi karaa inaad qaadato acetaminophen (Tylenol), oo ah warqad dhakhtar miisaanka lagu iibsado oo dhan iyo dawada qandhada si looga caawiyo astaamahan. La hadal dhakhtarkaaga haddii astaamahan ay adag tahay in la maareeyo ama ay noqdaan kuwo daran.

Ka taxaddar inaad cabto dareere kugu filan inta lagu guda jiro daaweyntaada ugu horreeya ee interferon alfa-2b.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Haddii aad seegto qiyaasta tallaalka interferon alfa-2b, isku dur qiyaastaada xigta isla marka aad xusuusato ama aad awooddo inaad siiso. Ha u isticmaalin isku-darka interferon alfa-2b laba maalmood oo isku xigta. Ha isku durin laba qaadasho si aad ugu kabtid qiyaasta la seegay. Wac dhakhtarkaaga haddii aad seegto qiyaasta daawada oo aad qabtid su'aalo ku saabsan waxa la sameeyo.

Isku-darka Interferon alfa-2b wuxuu sababi karaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• nabar, dhiig bax, xanuun, casaan, barar, ama cuncun meeshii aad ku mudday interferon alfa-2b
• murqo xanuun
• beddelo awoodda dhadhaminta
• timo lumis
• dawakhaad
• afka qalalan
• dhibaatooyinka feejignaanta
• dareemid qabow ama kuleyl
• isbedelka miisaanka
• isbeddelada maqaarka

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama mid ama kuwa ku taxan DIGNIIN MUHIIM AH ama qaybaha taxadarka khaaska ah, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo deg deg ah:

• finan
• finan
• diirka maqaarka
• cuncun
• neefsashada ama wax liqidda oo ku adkaata
• bararka indhaha, wejiga, afka, carrabka, ama cunaha
• isbedelka aragga
• calool xanuun, danqasho ama barar
• hurdi maqaarka ama indhaha
• daal xad dhaaf ah
• jahwareer
• shuban
• cunto xumo
• lallabbo
• matagid
• dhabar xanuun
• miyir beelid
• kabuubyo, gubasho ama ruxitaan gacmaha ama cagaha

Isku-darka Interferon alfa-2b wuxuu sababi karaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn inta aad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi qaboojiyaha, laakiin ha qaboojin. Marka la isku daro, isla markiiba u isticmaal. Waxaa lagu keydin karaa qaboojiyaha ilaa 24 saacadood kadib markii la qaso. Iska tuur wixii daawo ah ee dhacay ama aan loo baahnayn. Farmashiistahaaga kala hadal sida saxda ah ee daaweynta looga takhalusi karo.

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Intron A^®