Cudurka sambabada ee sambabada

Pulmonary alveolar proteinosis (PAP) waa cudur dhif ah oo nooc borotiin ah uu ku soo kordho kiishashka hawadu (alveoli) ee sambabada, taasoo ka dhigaysa neefsashada oo adkaata. Sambabada waxaa loola jeedaa sambabaha.

Xaaladaha qaarkood, sababta keentay PAP lama yaqaan. Kuwa kale, waxay ku dhacdaa infakshanka sanbabada ama dhibaato difaac. Waxay sidoo kale ku dhici kartaa kansarrada nidaamka dhiigga, iyo soo-gaadhista heerarka sare ee walxaha deegaanka, sida silica ama aluminium boodhka.

Dadka da'doodu udhaxeyso 30 ilaa 50 sano jir ayaa badiyaa saameeya. PAP waxaa lagu arkaa ragga inta badan dumarka. Nooc ka mid ah cilladaan ayaa jirta dhalashada (congenital).

Calaamadaha PAP waxaa ka mid noqon kara mid ka mid ah kuwan soo socda:

• Neefta oo kugu yaraata
• Qufac
• Daal
• Qandho, haddii uu jiro infekshan sambabaha ah
• Maqaarka Bluish (cyanosis) xaaladaha daran
• Miisaanka oo yaraada

Mararka qaarkood, ma jiraan wax astaamo ah.

Bixiyaha xanaanada caafimaadka wuxuu ku dhagaysan doonaa sambabaha stethoscope waxaana laga yaabaa inuu maqlo dildilaaca sanbabada. Badanaa, baaritaanka jirka waa caadi.

Tijaabooyinka soo socda waa la samayn karaa:

• Bronchoscopy oo leh cusbada lagu dhaqo sambabada (lavage)
• Raajo xabadka ah
• Baadhitaanka CT ee laabta
• Imtixaanada shaqada sanbabada
• Qalitaanka sambabka oo furan (biopsy biopsy)

Daaweyntu waxay ku lug leedahay ka-maydhista borotiinka sambabka (dhammaan-sanbabka lavage) waqti ka waqti. Dadka qaarkiis ayaa laga yaabaa inay u baahdaan xubin sambabal ah. Ka fogaanshaha busta laga yaabo inay sababtay xaalada ayaa sidoo kale lagu talinayaa.

Daaweyn kale oo laga yaabo in la isku dayo waa daawo dhiiga kicisa oo loo yaqaan 'granulocyte-macrophage colony stimulating factor (GM-CSF), taas oo ka maqan dadka qaar oo qaba alveolar proteinosis.

Kheyraadkaani waxay ku siin karaan macluumaad dheeraad ah PAP:

• Ururka Qaranka ee Dhibaatooyinka Nadir - rarediseases.org/rare-diseases/pulmonary-alveolar-proteinosis
• PAP Foundation - www.papfoundation.org

Dadka qaarkooda ee leh PAP waxay galaan cafis. Qaar kale waxay leeyihiin hoos u dhac ku dhaca infekshinka sambabaha (neefsashada oo shaqeysa) taas oo ka sii daraysa, waxaana laga yaabaa inay u baahdaan tallaal sambabo.

Wac bixiyahaaga haddii aad isku aragto astaamo neefsasho oo daran. Neefsashada oo kugu yaraata waqti ka dib waxay calaamad u noqon kartaa in xaaladdaadu ay isu beddeleyso xaalad caafimaad oo degdeg ah.

PAP; Alveolar proteinosis; Pulmonary alveolar fosforypoppopinosis; Alveolar lipoproteinosis phospholipidosis

• Cudurka sanbabada ee dhexdhexaadka ah - dadka waaweyn - dheecaan

• Nidaamka neefsashada

Levine SM. Ciladaha buuxinta Alveolar. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 26aad. Philadelphia, PA: Elsevier; 2020: baab 85.

Trapnell BC, Luisetti M. Pulmonary alveolar proteinosis cillad. Gudaha: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray iyo Nadel Buugga Buugga Caafimaadka Neefsashada. 6aad ed. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 70.