5-HIAA baaritaanka kaadida

5-HIAA waa baaritaan kaadi ah oo cabiraya qadarka 5-hydroxyindoleacetic acid (5-HIAA). 5-HIAA waa wax soo saar burbura hormoonka loo yaqaan serotonin.

Tijaabadani waxay sheegaysaa inta 5-HIAA ee jirku soo saarayo. Sidoo kale waa hab lagu cabbiro inta serotonin ee jirka ku jira.

24 saacadood kaadi ah ayaa loo baahan yahay. Waxaad u baahan doontaa inaad kaadidaada ku soo ururiso in ka badan 24 saacadood weel ay bixiso shaybaarku. Bixiyaha xanaanada caafimaadka ayaa kuu sheegi doona sida tan loo sameeyo. Raac tilmaamaha sida saxda ah.

Bixiyahaaga ayaa ku amri doona, haddii loo baahdo, inaad joojiso qaadashada dawooyinka faragelinta ku yeelan kara baaritaanka.

Daawooyinka kordhin kara cabirka 5-HIAA waxaa ka mid ah acetaminophen (Tylenol), acetanilide, phenacetin, glyceryl guaiacolate (oo laga helo sharoobooyin badan oo qufac ah), methocarbamol, iyo keyd.

Daawooyinka yareyn kara cabirrada 5-HIAA waxaa ka mid ah heparin, isoniazid, levodopa, monoamine oxidase inhibitors, methenamine, methyldopa, phenothiazines, iyo tricyclic antidepressants.

Waxaa laguu sheegi doonaa inaadan cunin cuntooyinka qaarkood 3 maalmood baaritaanka ka hor. Cunnooyinka faragalin kara cabirka 5-HIAA waxaa kamid ah burooyinka, cananaaska, muuska, ukunta, yaanyada, avocados, iyo iniinka.

Tijaabadu waxay ku lug leedahay oo keliya kaadida caadiga ah, mana jiraan wax dhib ah.

Tijaabadani waxay cabirtaa heerka 5-HIAA ee kaadida. Badanaa waxaa loo sameeyaa si loo ogaado burooyinka qaarkood ee habka dheef-shiidka (burooyinka kansarka) iyo in lala socdo xaaladda qofka.

Tijaabada kaadida ayaa sidoo kale loo isticmaali karaa in lagu ogaado cilad la yiraahdo systemic mastocytosis iyo burooyinka qaar ee hormoonka.

Heerka caadiga ah waa 2 ilaa 9 mg / 24h (10.4 ilaa 46.8 olmol / 24h).

Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabiyaan shaybaarro kala duwan. Kala hadal adeeg bixiyahaaga macnaha natiijooyinka baaritaankaaga gaarka ah.

Natiijooyinka aan caadiga ahayn waxaa laga yaabaa inay u sabab yihiin:

• Burooyinka nidaamka endocrine ama burooyinka kansarka
• Kordhinta unugyada difaaca jirka ee loo yaqaan unugyada muruqyada ee dhowr xubnood (systemic mastocytosis)

Ma jiraan wax khatar ah oo ka imaan kara baaritaankaan.

HIAA; 5-hydroxyindole acetic acid; Dheef-shiid kiimikaadka Serotonin

Chernecky CC, Berger BJ. H. Gudaha: Chernecky CC, Berger BJ, eds. Tijaabooyinka Shaybaarka iyo Nidaamyada Baadhista. 6aad ed. Philadelphia, PA: Elsevier Saunders; 2013: 660-661.

Wolin EM, Jensen RT. Burooyinka Neuroendocrine. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 26aad. Philadelphia, PA: Elsevier; 2020: cutubka 219.