Cirbadda Foscarnet

Qanacsan

• Kahor intaadan isticmaalin cirbadeynta foscarnet,
• Foscarnet waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:
• Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

Foscarnet waxay sababi kartaa dhibaatooyin kelyo oo daran. Halista waxyeelada kilyaha waxay ku badan tahay dadka fuuqbaxay. Dhakhtarkaaga ayaa amri doona baaritaano shaybaar ka hor iyo inta daaweyntaadu socoto si loo arko haddii kilyahaaga ay saameyn ku leeyihiin daawadan. U sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa qabtid cudurka kalyaha ama haddii aad leedahay af qalalan, kaadi madow, dhididku kaa yaraaday, maqaarka oo qallalan, iyo calaamadaha kale ee fuuqbaxa ama aad dhawaan yeelatay shuban, matag, qandho, infekshin, dhidid badan, ama awoodin inaad cabto dareereyaal kugu filan. U sheeg dhakhtarkaaga iyo farmashiistaha haddii aad qaadanayso acyclovir (Zovirax); antibiyootikada aminoglycoside sida amikacin, kanamycin, neomycin, paromomycin, streptomycin, iyo tobramycin; amphotericin (Abelcet, Ambisome); cyclosporine (Gengraf, Neoral, Sandimmune); methotrexate (Otrexup, Rasuvo, Trexall); pentamidine (Nebupent, Pentam), ama tacrolimus (Astagraf, Prograf). Waxaa laga yaabaa in dhakhtarkaagu uusan rabin inaad hesho cirbadda foscarnet. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba wac dhakhtarkaaga: kaadida oo yaraata; barar wejiga, gacmaha, gacmaha, cagaha, anqawyada, ama lugaha hoose; daal aan caadi ahayn; ama daciifnimo.

Foscarnet waxay sababi kartaa qalal. U sheeg dhakhtarkaaga haddii aad isku aragto ama aad waligaa suuxdo, dhibaatooyin kale oo habdhiska neerfaha ah, ama haddii aad waligaa dhiiggaaga ku yaraado heer kaalshiyam ah. Dhakhtarkaaga ayaa laga yaabaa inuu hubiyo heerka kalsiyum ee dhiiggaaga ka hor intaadan helin mudista foscarnet iyo inta lagu jiro daweynta. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba wac dhakhtarkaaga: qalal; kabuubyo ama gariir ku dhaca afka ama faraha ama suulasha; dhakhso, garaacid, ama wadno garaac aan caadi ahayn; ama murqo xanuun.

Dhammaan ballamaha la dhig dhakhtarkaaga, oo ay ku jiraan dhakhtarka indhaha, iyo sheybaarka. Dhakhtarkaaga ayaa amri doona baaritaano gaar ah, oo ay ku jiraan baaritaanada indhaha ee xilliyada, kahor iyo inta daaweyntaadu socoto si loo hubiyo jawaabta jirkaaga ee foscarnet. Dhakhtarkaagu wuxuu kaloo amri karaa electrocardiogram-ka (ECG; baaritaanka cabiraya dhaqdhaqaaqa korantada ee wadnaha) kahor iyo inta lagaa daaweynayo.

Cirbadeynta Foscarnet waxaa loo isticmaalaa kaligeed ama ganciclovir (Cytovene) si loogu daaweeyo cytomegalovirus (CMV) retinitis (infekshinka indhaha ee sababi kara indho la'aan) ee dadka qaba fayraska difaaca jirka ee aadanaha (HIV). Cirbadeynta Foscarnet ayaa sidoo kale loo isticmaalaa in lagu daaweeyo infekshinka herpes simplex virus (HSV) ee maqaarka iyo xuubka xabka (afka, futada) ee dadka nidaamka jirkooda uusan si caadi ah u shaqeynin iyo marka daaweynta acyclovir aysan caawin. Foscarnet waxay ku jirtaa nooc dawooyin ah oo loo yaqaan antiviral. Waxay ku shaqeysaa iyada oo hoos u dhigeysa koritaanka CMV iyo HSV. Foscarnet waxay xakameysaa cudurka 'CMV retinitis' iyo infekshinka HSV ee maqaarka iyo xuubka xabka laakiin ma daaweynayo infekshannadaas.

Cirbadeynta Foscarnet waxay u timaaddaa sidii dareere ah inuu ahaado xidid (xidid). Badanaa waxaa si tartiib ah loogu shubaa 1 ilaa 2 saacadood 8 ama 12 saacadood kasta. Dhererka daaweyntaadu waxay kuxirantahay sida aad ugu jawaabeyso daawada.

Waxaa laga yaabaa in lagugu mudo irbada foscarnet ee isbitaalka ama waxaad ku daaweyn kartaa guriga. Haddii guriga lagaa siin doono cirbadda foscarnet, daryeel caafimaad bixiyahaaga ayaa ku tusi doona sida loo isticmaalo daawada. Hubso inaad fahantay tilmaamahan, oo weydii daryeel caafimaad bixiyahaaga haddii aad wax su'aalo ah qabtid

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Cirbadeynta Foscarnet sidoo kale mararka qaarkood waxaa loo isticmaalaa in lagu daaweeyo lagana hortago infekshannada CMV ee bukaannada qaba fayraska difaaca jirka ee aadanaha (HIV). Kala hadal dhakhtarkaaga khataraha aad u leedahay isticmaalka dawadan xaaladaada.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan isticmaalin cirbadeynta foscarnet,

• u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad xasaasiyad ku leedahay foscarnet, dawooyinka kale, ama wax ka mid ah waxyaabaha ku jira irbadda foscarnet. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto dawooyinka ku taxan qaybta DIGNIIN MUHIIM AH iyo mid ka mid ah kuwan soo socda: amiodarone (Cordarone, Nexterone, Pacerone); azithromycin (Zithromax); clarithromycin (Biaxin); diuretics ('kaniiniyada biyaha') sida bumetanide, ethacrynic acid (Edecrin), furosemide (Lasix), ama torsemide (Demadex); dofetilide (Tikosyn); erythromycin (E-mycin, Ery-Tab, kuwa kale); antibiyootigga fluoroquinolone oo ay ka mid yihiin ciprofloxacin (Cipro), gatifloxacin (Tequin), levofloxacin (Levaquin), moxifloxacin (Avelox), iyo ofloxacin (Floxin); daawooyinka cudurada maskaxda ama lallabbo; procainamide; quinidine (oo ku taal Nuedexta); ritonavir (Norvir, Kaletra); saquinavir (Invirase); sotalol (Betapace, Sorine); iyo tricyclic antidepressants ('mood elevators') sida amitriptyline, desipramine (Norpramin), doxepin (Silenor), ama nortriptyline (Pamelor). Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca. Daawooyin kale oo badan ayaa sidoo kale laga yaabaa inay la falgalaan cirbadeynta foscarnet, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan.
• u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa QT sii dheereysay (wadna garaac aan caadi ahayn oo u horseedi kara suuxdin, miyir beelid, suuxdin, ama dhimasho lama filaan ah); heerarka hoose ee potassium ama magnesium ee dhiiggaaga; cudurka wadnaha; ama haddii aad ku jirto cunto milixdu ku yar tahay.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanaysid duritaanka foscarnet, wac dhakhtarkaaga.
• waa inaad ogaataa in foscarnet ay kaa dhigi karto mid dawakhsan ama wareersan. Gaari ha wadin ama ha ku shaqeynin mishiin ilaa aad ka ogaato sida daawadani kuu saameyneyso.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Foscarnet waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• cuncun, casaan, xanuun, ama barar meeshii lagaa duray
• lallabbo
• calool xanuun
• dhabar xanuun
• luminta rabitaanka cuntada ama culeyska jirka
• calool istaag
• madax xanuun
• aragtida isbeddelay
• guduudasho, cuncun, ama nabarro ku dhaca guska
• guduudasho, cuncun, ama nabarro ku wareegsan xubinta taranka

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:

• finan
• finan
• bararka indhaha, wejiga, dibnaha, carrabka, ama cunaha
• neefsashada ama wax liqidda oo ku adkaata
• xabad xanuun
• dhakhso, garaacid, ama wadno garaac aan caadi ahayn
• miyir beelid
• madax wareer
• miyir beelid
• matagid
• shuban
• qandho, dhaxan, qufac, ama calaamadaha kale ee infekshinka
• dhiigbax ama nabar aan caadi ahayn
• saxaro madow iyo tarry
• matag dhiig leh ama wax matag ah oo u eg qaxwaha
• maqaarka cirro leh
• neefta oo ku qabata
• jahwareer
• murqo xanuun ama casiraad
• dhidid badan

Foscarnet waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad isticmaaleyso daawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

• qalal
• kabuubyo ama gariir ku dhaca afka ama faraha ama suulasha
• kaadida oo yaraatay
• barar wajiga, gacmaha, gacmaha, cagaha, anqawyada, ama lugaha hoose
• daal ama daciifnimo aan caadi ahayn

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Foscavir^®