Cirbadda Isavuconazonium

Qanacsan

• Kahor intaadan helin cirbadeynta isavuconazonium,
• Cirbadda Isavuconazonium waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac takhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo deg-deg ah:
• Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

Cirbadeynta 'Isavuconazonium' waxaa loo isticmaalaa in lagu daaweeyo infekshannada daran ee fungal sida faafidda aspergillosis (infekshinka fungal ka bilaabma sambabaha oo ku faafta marinnada dhiigga ee xubnaha kale) iyo mucormycosis ku dhaca (infekshinka fungal ee badanaa ka bilowda sanka, maskaxda, ama sambabaha) . Cirbadda Isavuconazonium waxay ku jirtaa nooc ka mid ah daawooyinka loo yaqaan azole antifungals. Waxay ku shaqeysaa iyada oo hoos u dhigeysa koritaanka fangaska ee sababa infekshinka.

Cirbadeynta Isavuconazonium waxay u timaadaa sidii budo ah in lagu qaso dareere laguna durayo xididka (xididka). Badanaa waxaa la siiyaa ugu yaraan 1 saac 8dii saacadoodba mar lixda qiyaasood ee ugu horreeya ka dibna hal mar maalintii. Dhererka daaweyntaadu waxay kuxirantahay caafimaadkaaga guud, nooca cudurka aad qabtid, iyo sida ugu wanaagsan ee aad uga jawaabto daawada. Waxaa lagugu siin karaa cirbadda isavuconazonium ee isbitaalka ama waxaad ku daaweyn kartaa guriga. Haddii guriga lagaa siin doono cirbadeynta isavuconazonium, daryeel caafimaad bixiyahaaga ayaa ku tusi doona sida loo isticmaalo daawada. Hubso inaad fahantay tilmaamahan, oo weydii daryeel caafimaad bixiyahaaga haddii aad wax su'aalo ah qabtid.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan helin cirbadeynta isavuconazonium,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay isavuconazonium, fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole, dawooyin kale oo kasta, ama mid ka mid ah maaddooyinka ku jira irbadda isavuconazonium. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga haddii aad qaadanaysid carbamazepine (Carbatrol, Tegretol), ketoconazole (Nizoral), phenobarbital, rifampin (Rifadin, Rifamate), ritonavir (Norvir, Kaletra), or St. John’s wort. Dhakhtarkaagu wuxuu kuu sheegi doonaa inaad isticmaasho irbadda isavuconazonium haddii aad qaadanayso mid ama in kabadan oo dawooyinkan ah.
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: atorvastatin (Lipitor), bupropion (Aplenzin, Forfivo XL, Wellbutrin, Zyban), cyclosporine (Gengraf, Neoral, Sandimmune), digoxin (Digitek, Lanoxicaps, Lanoxin), midazolam, mycophenolate mofil ), sirolimus (Rapamune), ama tacrolimus (Prograf). Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca. Daawooyin kale oo badan ayaa sidoo kale la macaamili kara isavuconazonium, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan.
• u sheeg dhakhtarkaaga haddii adiga ama qof kale oo qoyskaaga ka mid ahi uu leeyahay ama uu weligiis ku dhacay cudurka QT Syndrome (xaalad kordhinaysa halista wadno-garaac aan caadi ahayn, wareer, suuxdin, ama dhimasho lama filaan ah). Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaadan qaadan cirbadeynta isavuconazonium.
• u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa dhibaato ka haysato wadnaha ama beerka.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanaysid irbadda isavuconazonium, wac dhakhtarkaaga.

Kala hadal dhakhtarkaaga wax ku saabsan cunitaanka canab-gacmeedka iyo cabitaanka casiir canab ah adoo qaadanaya dawadan.

Cirbadda Isavuconazonium waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• shuban
• calool istaag
• madax xanuun
• dhabar xanuun
• qufac
• dhibaato xagga hurdada ama hurdada ah
• walaac
• kacsan
• jahwareer
• rabitaanka cuntada oo yaraaday

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac takhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo deg-deg ah:

• finan
• finan
• cuncun
• xoqidda ama maqaarka oo bararaya
• lallabbo
• matagid
• hurdi maqaarka ama indhaha
• daal xad dhaaf ah
• astaamaha hargabka oo kale ah
• murqo xanuun, casiraad, ama daciifnimo
• garaaca wadnaha oo aan joogto ahayn
• barar gacmaha, cagaha, gacmaha ama lugaha
• neefsashada ama wax liqidda oo ku adkaata
• miyir beelid
• aragga oo xumaada
• dawakhaad
• qarqaryo
• kabuubyo, gubasho, ama xoqid gacmaha, gacmaha, cagaha, ama lugaha
• isbeddelo dareenkaaga taabashada

Cirbadda Isavuconazonium waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn inta aad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

• madax xanuun
• dawakhaad
• xanuun, gubasho, ama ruxruxasho gacmaha ama cagaha
• lulmid
• Dhibaatada diirada
• beddel dareenka dhadhanka
• afka qalalan
• kabuubyo afka ah
• shuban
• matagid
• casaan lama filaan ah wajiga, qoorta, ama xabadka kore
• walaac
• degganaansho la'aan
• garaaca ama garaaca wadnaha oo dhakhso ah
• isha u nugul iftiinka
• kalagoys xanuun

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu dalban karaa baaritaano shaybaar qaarkood si loo hubiyo jawaabta jirkaaga ee cirbadda isavuconazonium.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Cresemba^® I.V.