Qanjirka 'antiperoxidase': waa maxay iyo sababta ay u sareyn karto

Qanacsan

• Thyroid Antiperoxidase Sare
• 1. Hashimoto's thyroiditis
• 2. Cudurka xabaalaha
• 3. Uurka
• 4. Hoosudhaca hypothyroidism
• 5. Taariikhda qoyska

Qanjirka 'Thyroid antiperoxidase' (anti-TPO) waa antibody ay soo saarto nidaamka difaaca jirka ee weerara qanjirka 'thyroid', taasoo keenta isbeddelo ku yimaada heerarka hormoonnada ay soo saaraan qanjirka 'thyroid'. Qiimaha anti-TPO way ku kala duwan yihiin sheybaarka ilaa sheybaarka, iyadoo qiimaha la kordhiyay badiyaa uu muujinayo cudurada iswada.

Si kastaba ha noqotee, qadarka autoantibody-kan tayroodhka ah ayaa ku kordhin kara xaalado dhowr ah, sidaa darteed waxaa muhiim ah in cudurka la ogaado iyadoo la tixgelinayo natiijada baaritaannada kale ee la xiriira qanjirka 'thyroid', sida qanjidhada kale ee tayroodhka iyo qiyaasta TSH, T3 iyo T4. Ogow tijaabooyinka la muujiyay si loo qiimeeyo qanjirka 'thyroid'.

Thyroid Antiperoxidase Sare

Qiimayaasha kordhay ee tayroodh antiperoxidase (anti-TPO) ayaa badanaa muujinaya calaamadaha cudurada tayroodhka ee difaaca jirka, sida Hashimoto's thyroiditis iyo cudurka Graves, tusaale ahaan, si kastaba ha noqotee waa lagu kordhin karaa xaaladaha kale, sida uurka iyo hypothyroidism. Sababaha ugu muhiimsan ee kor u kaca qanjirka 'thyroid antiperoxidase' waa:

1. Hashimoto's thyroiditis

Hashimoto's thyroiditis waa cudur isdifaaca jirka oo habka difaaca jirka uu u weeraro qanjirka 'thyroid', carqaladeeyo soo saarista hormoonnada tayroodhka iyo natiijada calaamadaha cudurka 'hypothyroidism', sida daal saa'id ah, miisaanka oo kordha, murqo xanuun iyo daciifinta timaha iyo ciddiyaha.

Hashimoto's thyroiditis waa mid ka mid ah sababaha ugu waaweyn ee kororka tayroodh antiperoxidase, si kastaba ha noqotee waxaa lagama maarmaan ah in la sameeyo baaritaano dheeri ah si loo buuxiyo baaritaanka. Fahmaan waxa Hashimoto tayroodhku yahay, calaamadaha iyo sida loo daaweeyo.

2. Cudurka xabaalaha

Cudurka 'Graves' waa mid ka mid ah xaaladaha ugu waaweyn ee daawada tayroodh antiperoxidase aad u sarreyso oo dhacdo maxaa yeelay autoantibody-kan ayaa si toos ah ugu shaqeeya qanjirka 'thyroid' wuxuuna kiciyaa soosaarka hormoonnada, taasoo keenta astaamaha astaamaha cudurka, sida madax xanuun, indho ballaaran, miisaanka oo yaraada, dhididka, daciifnimada murqaha iyo bararka cunaha, tusaale ahaan.

Waa muhiim in cudurka Graves la aqoonsado loona daaweeyo si sax ah si loo yareeyo astaamaha, daaweynta oo uu tilmaamayo dhaqtarku iyadoo ay ku xiran tahay darnaanta cudurka, iyo isticmaalka daawada, daaweynta iodine ama qalliinka tayroodhka ayaa lagula talin karaa. Waxbadan ka baro cudurka qabriga iyo sida loo daweeyo.

3. Uurka

Sababtoo ah isbeddelada hoormoonka ee uurka ku dhaca, waxaa macquul ah inay sidoo kale jiraan isbeddelo la xiriira qanjirka 'thyroid', oo la aqoonsan karo, oo ay ku jiraan, kororka heerarka tayroodh antiperoxidase ee dhiigga ku jira.

Iyada oo ay taasi jirto, haweeneyda uurka leh qasab maahan inay isbeddelo qanjirka 'thyroid'. Sidaa darteed, waa muhiim in la cabbiro anti-TPO bilowga uurka si dhakhtarku ula socdo heerarka inta lagu jiro uurka oo uu hubiyo halista ah inuu ku dhaco tayroodh dhalmada ka dib dhalmada, tusaale ahaan.

4. Hoosudhaca hypothyroidism

Subclinical hypothyroidism waxaa lagu gartaa hoos u dhac ku yimaada waxqabadka qanjirka 'thyroid' kaas oo aan soo saarin astaamo waxaana lagu ogaadaa kaliya baaritaanka dhiigga, taas oo heerarka caadiga ah ee T4 iyo kordhinta TSH la xaqiijiyo.

In kasta oo qiyaasta anti-TPO aan sida caadiga ah loogu tilmaamin ogaanshaha cudurka hypothyroidism subclinical, dhakhtarka ayaa laga yaabaa inuu amro tijaabadan si loo qiimeeyo horumarka hypothyroidism iyo in la hubiyo in qofku si fiican uga jawaabayo daaweynta. Tani waa macquul sababtoo ah antibody-kan wuxuu si toos ah ugu shaqeeyaa enzyme-ka xakameynaya soosaarka hoormoonka tayroodhka. Marka, marka la cabirayo tayroodh antiperoxidase ee subclinical hypothyroidism, waxaa suurtagal ah in la xaqiijiyo in hoos u dhaca xaddiga anti-TPO uu weheliyo sharciyeynta heerarka TSH ee dhiigga.

Baro sida loo aqoonsado loona daaweeyo hypothyroidism.

5. Taariikhda qoyska

Dadka ehelka u ah cudurada tayroodh ee difaaca jirka ayaa laga yaabaa inay wax ka badaleen qiyamka antibodyroxioxide antibody, taas oo aan ahayn calaamad muujinaysa inay iyaguna cudur qabaan. Sidaa darteed, waxaa muhiim ah in la qiimeeyo qiimaha anti-TPO oo ay weheliso baaritaanada kale ee dhakhtarku codsaday.