Hemoglobin Electrophoresis

Qanacsan

• Waa maxay electrophoresis haemoglobin?
• Maxaa loo adeegsadaa?
• Maxaan ugu baahanahay electrophoresis haemoglobin?
• Maxaa dhaca inta lagu jiro electrophoresis haemoglobin?
• Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?
• Ma jiraan wax khatar ah oo ku iman kara koronto-yaqaan hemoglobin?
• Maxay natiijooyinka ka dhigan yihiin?
• Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado waxa ku saabsan hemoglobin electrophoresis?
• Tixraacyo

Waa maxay electrophoresis haemoglobin?

Hemoglobin waa borotiin ku jira unugyadaada dhiigga cas ee qaada oksijiinta sambabahaaga illaa jirka intiisa kale. Waxaa jira dhowr nooc oo ah haemoglobin. Hemoglobin electrophoresis waa baaritaan lagu cabiro noocyada kala duwan ee haemoglobin ee dhiiga. Waxay kaloo eegtaa noocyada aan caadiga ahayn ee haemoglobin.

Noocyada caadiga ah ee haemoglobin waxaa ka mid ah:

• Hemoglobin (Hgb) A, nooca ugu badan ee haemoglobin ee dadka waaweyn ee caafimaadka qaba
• Hemoglobin (Hgb) F, hemoglobin uurjiif ah. Nooca haemoglobin waxaa laga helaa dhallaanka aan dhalan iyo kuwa hadda dhashay. HgbF waxaa badalay HgbA waxyar kadib dhalashada.

Haddii heerarka HgbA ama HgbF ay aad u sarreeyaan ama aad u hooseeyaan, waxay muujin kartaa noocyo dhiig la'aan ah.

Noocyada aan caadiga ahayn ee haemoglobin waxaa ka mid ah:

• Hemoglobin (Hgb) S. Nooca haemoglobin waxaa laga helaa cudurka unuga sickle cell. Cudurka Sickle cell waa cillad la iska dhaxlo oo jidhka u keenta inuu sameeyo unugyo dhiig oo cas cas oo adag, oo leh qaab-xanuun. Unugyada dhiigga cas ee caafimaadka qaba way jilicsan yihiin si ay si fudud ugu dhex maraan xididdada dhiigga. Unugyada jiradu waxay ku dhegi karaan xididdada dhiigga, taasoo sababi karta xanuun daran oo joogto ah, infekshanno, iyo dhibaatooyin kale.
• Hemoglobin (Hgb) C. Nooca haemoglobin si fiican ugama qaado oksijiinta. Waxay sababi kartaa nooc yar oo dhiig yaraan ah.
• Hemoglobin (Hgb) E. Nooca haemoglobin waxaa badanaa laga helaa dadka ka soo jeeda Koonfur-bari Aasiya. Dadka qaba HgbE badiyaa ma laha calaamado ama astaamo fudud oo dhiig-yaraan ah.

Baadhitaanka haemoglobin electrophoresis wuxuu ku dabbaqayaa korontada tijaabada dhiiga. Tani waxay kala soocdaa noocyada caadiga ah iyo kuwa aan caadiga ahayn ee haemoglobin. Nooc kasta oo haemoglobin ah ayaa markaa loo qiyaasi karaa si shaqsi ah.

Magacyada kale: Hb electrophoresis, qiimeynta haemoglobin, qiimeynta hemoglobinopathy, jajabka haemoglobin, Hb ELP, shaashadda sickle cell

Maxaa loo adeegsadaa?

Hemoglobin electrophoresis wuxuu cabiraa heerarka haemoglobin wuxuuna raadiyaa noocyada aan caadiga ahayn ee haemoglobin. Badanaa waxaa loo isticmaalaa in lagu caawiyo baaritaanka dhiig-yaraanta, cudurada unugyada sickle cell, iyo cudurada kale ee haemoglobin.

Maxaan ugu baahanahay electrophoresis haemoglobin?

Waxaad u baahan kartaa baaritaan haddii aad isku aragto astaamaha cudurka haemoglobin. Kuwaas waxaa ka mid ah:

• Daal
• Maqaarka cirro leh
• Cagaarshow / Jaaleysiis, waa xaalad keenta in maqaarkaaga iyo indhahaadu huruud noqdaan
• Xanuun daran (cudurka unuga sickle)
• Dhibaatooyinka koritaanka (carruurta)

Haddii aad ilmo dhashay, ilmahaaga cusub waxaa lagu tijaabin doonaa qayb ka mid ah baaritaanka dhallaanka cusub. Baaritaanka dhallaanka cusub waa koox baaritaanno ah oo la sameeyo inta badan dhallaanka Mareykanka waxyar uun ka dib dhalashada. Baadhitaanku wuxuu hubiyaa xaalado kala duwan. Qaar badan oo ka mid ah xaaladahan waa la daaweyn karaa haddii goor hore la helo.

Waxa kale oo laga yaabaa inaad rabto baadhitaan haddii aad khatar ugu jirto inaad dhasho ilmo qaba cudurka sickle cell ama cillad kale oo hiddo-hemoglobin ah oo laga dhaxlo. Waxyaabaha halista keena waxaa ka mid ah:

• Taariikhda qoyska
• Asalka asalka
  • Dalka Mareykanka, dadka badankood ee qaba cudurka sickle cell waxay ka soo jeedaan Afrikaanka.
  • Thalassaemia, oo ah cillad kale oo hemoglobin ah oo la iska dhaxlo, ayaa ku badan dadka ku nool Talyaaniga, Griigga, Bariga Dhexe, Koonfurta Aasiya, iyo Afrikaanka.

Maxaa dhaca inta lagu jiro electrophoresis haemoglobin?

Xirfadlaha daryeelka caafimaadka ayaa tijaabo dhiig ka qaadi doona xididka gacantaada, isagoo isticmaalaya cirbad yar. Kaddib cirbada la geliyo, qadar yar oo dhiig ah ayaa lagu ururin doonaa tuubada baaritaanka ama fijaan. Waxaa laga yaabaa inaad dareento xoog wax yar ah markii irbadda ay soo galayso ama ay ka baxeyso. Tani badanaa waxay qaadataa in ka yar shan daqiiqo.

Si loo tijaabiyo ilmaha dhasha ah, daryeel caafimaad ayaa ku nadiifin doona ciribta canuggaaga aalkolo wuxuuna ciribta ciribta ku durayaa irbad yar. Bixiyuhu wuxuu ururin doonaa dhawr dhibcood oo dhiig ah oo uu faashad ku rido goobta.

Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?

Uma baahnid wax diyaargarow gaar ah oo loogu talagalay baaritaanka hemoglobin electrophoresis.

Ma jiraan wax khatar ah oo ku iman kara koronto-yaqaan hemoglobin?

Khatar aad u yar baa jirta in dhiig lagaa qaado. Waxaa laga yaabaa inaad xanuun yar ama nabar ku yeelato barta irbadda lagu muday, laakiin astaamaha badankood si dhakhso leh ayey u baxaan.

Ilmahaagu wuxuu dareemi karaa xoogaa yar oo qanjaruufo marka cidhibku xidhmayaan, oo nabar yar ayaa ka soo bixi kara goobta. Tani waa inay dhaqso u tagtaa.

Maxay natiijooyinka ka dhigan yihiin?

Natiijooyinkaagu waxay muujinayaan noocyada haemoglobin ee la helay iyo heerarka mid kasta.

Heerarka haemoglobin ee aad u sarreeya ama aad u hooseeya ayaa macnaheedu noqon karaa:

• Thalassaemia, waa xaalad saameysa soo saarista haemoglobin. Calaamaduhu waxay u dhexeeyaan mid fudud illaa mid daran.
• Dabeecadda unugyada jirrada. Xaaladdan oo kale, waxaad leedahay hal hiddo-wadaha unugga jiran iyo hal hiddo-wadaha caadiga ah. Badanaa dadka leh astaamaha unugga sickle ma qabaan dhibaatooyin caafimaad.
• Cudurka Sickle cell
• Cudurka Hemoglobin C, xaalad sababa nooc khafiif ah oo dhiig yaraan ah mararka qaarkoodna beerka weyn iyo kalagoysyada oo weynaada
• Cudurka Hemoglobin S-C, xaalad sababa qaab fudud ama dhexdhexaad oo ah cudurka unugyada sickle cell

Natiijooyinkaaga ayaa sidoo kale laga yaabaa inay muujiyaan in cillad gaar ah ay tahay mid fudud, dhexdhexaad ah, ama daran.

Natiijooyinka baaritaanka Hemoglobin electrophoresis waxaa badanaa lala barbardhigaa baaritaannada kale, oo ay ku jiraan tirinta dhiigga oo dhameystiran iyo dheecaanka dhiigga. Haddii aad su'aalo ka qabtid natiijooyinkaaga, la hadal daryeel caafimaad bixiyahaaga.

Wax badan ka baro baaritaanka shaybaarka, kala duwanaanshaha tixraaca, iyo fahamka natiijooyinka.

Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado waxa ku saabsan hemoglobin electrophoresis?

Haddii aad khatar ugu jirto inaad dhasho ilmo qaba hiddo-wadaha hemoglobin, waxaad u baahan kartaa inaad la hadasho lataliyaha hidda-socodka. Lataliyaha hidaha ayaa ah xirfadle si gaar ah ugu tababaran hidaha iyo baaritaanka hidaha. Isaga ama iyada ayaa kaa caawin kara inaad fahamto cillada iyo halista aad ugu gudbin karto ilmahaaga.

Tixraacyo

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2. Kliinikada Cleveland [Internet]. Cleveland (OH): Isbitaalka Cleveland; c2020. Sickle Cell Anemia: Guudmarka; [daliishaday 2020 Jan 10]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://my.clevelandclinic.org/health/diseases/4579-sickle-cell-anemia
3. Caafimaadka Carruurta Saacadaha (Internetka). Jacksonville (FL): Mu'asasada Nemours; c1995–2020. Tijaabada Dhiigga: Hemoglobin Electrophoresis; [daliishaday 2020 Jan 10]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://kidshealth.org/en/parents/test-electrophoresis.html
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9. Machadka Wadnaha, Sambabka, iyo Machadka Dhiiga [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Cudurka Sickle Cell; [daliishaday 2020 Jan 10]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.nhlbi.nih.gov/health-topics/sickle-cell-disease
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15. Caafimaadka UW [Internetka]. Madison (WI): Jaamacadda Wisconsin Isbitaalada iyo Maamulka Rugta; c2020. Macluumaadka Caafimaadka: Hemoglobin Electrophoresis: Maxaa Loo Sameeyay; [cusboonaysiiyay 2019 Mar 28; daliishaday 2020 Jan 10]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html#hw39110

Macluumaadka ku yaal boggan waa in aan loo isticmaalin beddel daryeel caafimaad oo xirfad leh ama talo. La xiriir bixiye daryeel caafimaad haddii aad su'aalo ka qabtid caafimaadkaaga.