Caano-alkali syndrome

Cudurka 'Milk-alkali syndrome' waa xaalad ay ku jiraan heer sare oo kaalshiyam ah jirka (hypercalcemia). Tani waxay keenaysaa isbeddel ku yimaadda aashitada jirka / dheelitirka jirka ee loo yaqaan 'alkaline' (metabolic alkalosis). Natiijo ahaan, waxaa jiri kara luminta shaqada kelyaha.

Cudurka 'Milk-alkali syndrome' waxaa had iyo jeer sababa qaadashada waxyaabo badan oo kaalshiyam ah, badanaa qaab kaalshiyam kaarboonayt ah. Kaalshiyamka Kaalshiyamka waa kaalshiyam kaalshiyam caadi ah. Waxaa badanaa loo qaataa si looga hortago ama loo daweeyo lafaha luminta (osteoporosis). Kaalshiyamka kaalshiyamka sidoo kale waa maado laga helo antacids (sida Tums).

Heer sare oo fiitamiin D ah oo jirka ku jira, sida qaadashada nafaqada, ayaa sii xumeyn kara caanaha-alkali syndrome.

Kaydinta kaalshiyamka ku jirta kalyaha iyo unugyada kale waxay ku dhici kartaa caanaha-alkali syndrome.

Bilowga, xaaladdu badanaa ma laha wax calaamado ah (asymptomatic). Markay astaamuhu dhacaan, waxaa ka mid noqon kara:

• Dhabarka, jirka dhexdiisa, iyo dhabarka hoose ee xanuunka kiliyaha (oo laxiriira dhagxaanta kilyaha)
• Jahwareer, dhaqan qariib ah
• Calool fadhiga
• Niyad jab
• Kaadi badan
• Daal
• Wadne garaac aan caadi ahayn (arrhythmia)
• Lalabbo ama matagid
• Dhibaatooyinka kale ee ka dhalan kara kalyaha oo shaqeynaya

Kaydinta kaalshiyamka ku jirta unugyada kilyaha (nephrocalcinosis) ayaa laga arki karaa:

• Raajo
• CT iskaanka
• Ultrasound

Tijaabooyinka kale ee loo isticmaalo in lagu sameeyo cudurka waxaa ka mid noqon kara:

• Heerarka korantada si loo hubiyo heerarka macdanta ee jirka ku jirta
• Electrocardiogram (ECG) si loo hubiyo dhaqdhaqaaqa korantada ee wadnaha
• Electroencephalogram (EEG) si loo cabiro dhaqdhaqaaqa korantada maskaxda
• Heerka sifeynta Glomerular (GFR) si loo hubiyo sida wanaagsan ee kilyaha u shaqeynayaan
• Heerka kaalshiyamka dhiigga

Xaaladaha daran, daaweyntu waxay ku lug leedahay siinta dareereyaasha xididka (IV). Haddii kale, daaweyntu waxay ku lug leedahay cabitaanno cabitaanno ah oo ay weheliso yaraynta ama joojinta kaalshiyamka kaabashka ah iyo dawooyinka lidka ku ah ee kaalshiyamka ku jira. Faytamiin D-ga ayaa sidoo kale loo baahan yahay in la yareeyo ama la joojiyo.

Xaaladdan badanaa waa la beddeli karaa haddii shaqada kelyaha ay caadi ahaato. Kiisaska daran ee daba dheeraaday waxay u horseedi karaan kalyo xanuun joogto ah oo u baahan sifayn.

Dhibaatooyinka ugu caansan waxaa ka mid ah:

• Kalsiyam-ka ku jira unugyada (calcinosis)
• Kelyaha oo hawl gab
• Dhagaxaanta kilyaha

La xiriir daryeelahaaga caafimaadka haddii:

• Waxaad qaadataa waxyaabo badan oo kaalshiyam ah ama waxaad badanaa isticmaashaa antacids ka kooban kaalshiyam, sida Tums. Waxaa laga yaabaa inaad u baahato in lagaa hubiyo caanaha-alkali syndrome.
• Waxaad leedahay wax calaamado ah oo kuu soo jeedin kara dhibaatooyinka kelyaha.

Haddii aad badanaa isticmaasho antacids ka kooban kaalshiyam, u sheeg bixiyahaaga dhibaatooyinka dheefshiidka. Haddii aad isku dayeyso inaad ka hortagto lafo-beelka, ha u qaadin wax ka badan 1.2 garaam (1200 miligram) oo kaalshiyam ah maalin kasta illaa bixiyahaagu ku faray mooyee.

Calcium-alkali syndrome; Cope syndrome; Xanuunka Burnett; Hypercalcemia; Cilladaha dheef-shiid kiimikaadka

Bringhurst FR, Demay MB, Kronenberg HM. Hormoonnada iyo ciladaha dheef-shiid kiimikaadka. Gudaha: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Buugga Buugga Endocrinology. 14aad. Philadelphia, PA: Elsevier; 2020: baab 29.

DuBose TD. Alkalosis metabolic. Gudaha: Gilbert SJ, Weiner DE, eds. Aasaaska Aasaaska Qaranka ee Kelyaha. 7aad ed. Philadelphia, PA: Elsevier; 2018: cutubka 14.