Kansarka 'Adrenocortical carcinoma'

Kansarka 'Adrenocortical carcinoma' (ACC) waa kansar ku dhaca qanjidhada adrenal. Qanjirada 'adrenal gland' waa laba qanjirro qaabeeya saddex-xagal. Hal qanjidh ayaa ku yaal keli kasta dusheeda.

ACC waxay ku badan tahay carruurta ka yar 5 sano jir iyo dadka waaweyn ee jira 40s iyo 50s.

Xaaladda waxaa laga yaabaa inay la xiriirto cudurka kansarka ee loo sii gudbiyo qoysaska (dhaxalka). Ragga iyo haweenkaba way horumarin karaan burooyinkan.

ACC waxay soo saari kartaa hormoonnada cortisol, aldosterone, estrogen, ama testosterone, iyo sidoo kale hormoonno kale. Haweenka burooyinka badanaa waxay soo daayaan hormoonadan, taasoo u horseedi karta astaamo lab ah.

ACC waa dhif iyo naadir. Sababta lama oga.

Calaamadaha koritaanka cortisol ama hormoonada kale ee qanjirka 'adrenal gland' waxaa ka mid noqon kara:

• Dufan, qulqulaya oo dhererkiisu sarreeyo xagga dambe ee qoorta ka hooseeya (buffalo hump)
• Biyo, weji wareegsan leh dhabanno jilicsan (wajiga dayaxa)
• Cayilka
• Kordhinta koritaanka (dherer gaaban)
• Virilization - muuqaalka astaamaha labka, oo ay kujirto timaha jirka oo siyaadaya (qaasatan wajiga), timaha xubinta taranka, finanka, qoto dheerida codka, iyo kintirka oo weynaaday (dumarka)

Astaamaha kordhinta aldosterone waxay la mid yihiin astaamaha potassium-yari, waxaana ka mid ah:

• Muruqyo xanuun
• Tabar darrida
• Xanuun caloosha ah

Bixiyaha xanaanada caafimaadka ayaa sameyn doona baaritaan jireed wuxuuna weydiin doonaa astaamahaaga.

Tijaabooyin dhiig ayaa la sameyn doonaa si loo hubiyo heerarka hoormoonka:

• Heerka ACTH wuu yaraan doonaa.
• Heerka Aldosterone ayaa noqon doona mid sareeya.
• Heerka Cortisol wuu sarreeyaa
• Heerka kaalshiyamta wuu yaraan doonaa.
• Hoormoonka ragga ama dumarka waxaa laga yaabaa inuu si aan caadi ahayn u sarreeyo.

Tijaabinta sawirka caloosha waxaa ka mid noqon kara:

• Ultrasound
• CT iskaanka
• MRI
• Baadhitaanka PET

Daaweynta aasaasiga ahi waa qalliin lagaga soo saarayo burada. ACC waxaa laga yaabaa inaysan ku fiicnayn daaweynta kemotherabi. Daawooyinka waa la siin karaa si loo yareeyo soo saarista cortisol, oo sababa astaamo badan.

Natiijadu waxay kuxirantahay sida ugu dhakhsaha badan ee baaritaanka loo sameeyo iyo in buurku fiday (metastasized). Burooyinka faafay waxay badanaa u horseedaan dhimasho 1 ilaa 3 sano gudahood.

Buroda waxay ku faafi kartaa beerka, lafaha, sambabka, ama meelo kale.

Wac daryeel bixiyahaaga haddii adiga ama ilmahaagu aad isku aragtaan astaamaha ACC, Cushing syndrome, ama koritaan la'aan.

Buro - adrenal; ACC - adrenal

• Qanjirada 'Endocrine'
• Adrenal metastases - CT scan
• Buro Adrenal - CT

Allolio B, Fassnacht M. kansarka 'Adrenocortical carcinoma'. Gudaha: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Dadka waaweyn iyo carruurta. 7aad ed. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 107.

Websaydhka Machadka Kansarka Qaranka. Daaweynta kansarka 'Adrenocortical carcinoma' (Dadka Waaweyn) (PDQ) - nooca caafimaadka mihnadeed. www.cancer.gov/types/adrenocortical/hp/adrenocortical-treatment-pdq. La cusbooneysiiyay Nofeembar 13, 2019. La helay Oktoobar 14, 2020.