17-hydroxycorticosteroids tijaabada kaadida
Baaritaanka 17-hydroxycorticosteroids (17-OHCS) wuxuu cabiraa heerka 17-OHCS ee kaadida.
24 saacadood kaadi ah ayaa loo baahan yahay. Waxaad u baahan doontaa inaad kaadidaada uruuriso in ka badan 24 saacadood. Bixiyaha xanaanada caafimaadka ayaa kuu sheegi doona sida tan loo sameeyo. Raac tilmaamaha sida saxda ah.
Bixiyaha ayaa ku amri doona, haddii loo baahdo, inaad joojiso daawooyinka faragelinta ku yeelan kara baaritaanka. Kuwaas waxaa ka mid noqon kara:
- Kiniiniyada ka hortagga uurka ee ka kooban estrogen
- Antibiyootikada qaarkood
- Glucocorticoids
Baadhitaanku wuxuu ku lug leeyahay oo keliya kaadida caadiga ah. Ma jiraan wax dhib ah.
17-OHCS waa badeecad la sameeyay markii beerka iyo unugyada kale ee jirka ay jabaan hormoonka steroid ee cortisol.
Tijaabadani waxay gacan ka geysan kartaa go'aaminta haddii jirku soo saarayo cortisol aad u badan. Baaritaanka waxaa loo isticmaali karaa in lagu ogaado cudurka 'Cushing syndrome'. Tani waa cilad dhacda marka jirku uu leeyahay heer sare oo joogto ah oo loo yaqaan 'cortisol'.
Mugga kaadida iyo kaadida creatinine waxaa badanaa lagu sameeyaa baaritaanka 17-OHCS isla waqtigaas. Tani waxay ka caawinaysaa adeeg bixiyaha inuu turjumo imtixaanka.
Tijaabadani badanaa lama sameeyo hadda. Tijaabada kaadi-cortisol ee bilaashka ah ayaa ah tijaabada baaritaanka wanaagsan ee cudurka Cushing.
Qiimaha caadiga ah:
- Lab: 3 ilaa 9 mg / 24 saac (8.3 ilaa 25 olmol / 24 saac)
- Dheddig: 2 ilaa 8 mg / 24 saac (5.5 ilaa 22 olmol / 24 saac)
Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabiyaan shaybaarro kala duwan. Kala hadal adeeg bixiyahaaga macnaha natiijooyinka baaritaankaaga gaarka ah.
Heer ka sareeya heerka caadiga ah ee 17-OHCS ayaa tilmaami kara:
- Nooc ka mid ah Cudurka 'Cushing syndrome' oo uu sababo buro ku taal qanjirka 'adrenal gland' oo soo saarta cortisol
- Niyad jab
- Daaweynta Hydrocortisone
- Nafaqo darrada
- Cayilka
- Uurka
- Sababta hoormoonka ee dhiig karka daran
- Cadaadis jireed ama shucuur oo daran
- Buro ku jirta qanjirka 'pituitary gland' ama meel kale oo jirka ka mid ah oo soo daayo hormoon loo yaqaan 'adrenocorticotropic hormone' (ACTH)
Heer ka hooseeya heerka caadiga ah ee 17-OHCS ayaa tilmaami kara:
- Qanjirada 'Adrenal glands' ma soo saaraan ku filan hormoonadooda
- Qanjirka 'pituitary gland' ma soo saaro ku filan hormoonnadiisa
- Yaraanta enzyme-ka la iska dhaxlo
- Qalliin hore looga saaray qanjirka 'adrenal gland'
Kaadinta wax kabadan 3 litir maalintii (polyuria) waxay kadhigi kartaa natiijada baaritaanka mid sare inkasta oo soosaarka cortisol uu yahay mid caadi ah.
Ma jiraan wax khatar ah oo ka imaan kara baaritaankaan.
17-OH corticosteroids; 17-OHCS
Chernecky CC, Berger BJ. 17-hydroxycorticosteroids (17-OHCS) - kaadi 24-saac ah. Gudaha: Chernecky CC, Berger BJ, eds. Tijaabooyinka Shaybaarka iyo Nidaamyada Baadhista. 6aad ed. St Louis, MO: Elsevier Saunders; 2013: 659-660.
Juszczak A, Morris DG, Grossman AB, Nieman LK. Cushing’s syndrome. Gudaha: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Dadka waaweyn iyo carruurta. 7aad ed. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 13.