Apolipoprotein B100

Apolipoprotein B100 (apoB100) waa borotiin door ka ciyaara dhaqaaqa kolestaroolka jirkaaga. Waa nooc ka mid ah lipoproteinka cufnaanta hooseeya (LDL).

Isbedelada (isbeddelada) ku dhaca apoB100 waxay sababi karaan xaalad loo yaqaan familial hypercholesterolemia. Kani waa nooc ka mid ah kolestaroolka sare ee loo gudbiyo qoysaska (la iska dhaxlo).

Maqaalkani wuxuu ka hadlayaa baaritaanka loo isticmaalay in lagu cabiro heerka apoB100 ee dhiiga.

Sambal dhiig ayaa loo baahan yahay.

Bixiyaha xanaanada caafimaadkaaga ayaa laga yaabaa inuu kuu sheego inaadan cunin waxna cabin 4 ilaa 6 saac baaritaanka ka hor.

Marka irbadda loo geliyo si dhiig u soo qaado, waxaad dareemi kartaa xanuun dhexdhexaad ah, ama keliya cirbad ama xinjixin. Ka dib, waxaa jiri kara xoogaa wax garaaca.

Badanaa, baaritaankan waxaa loo sameeyaa si looga caawiyo go'aaminta sababta ama nooca gaarka ah ee kolestaroolka dhiigga sareeya. Ma cadda in macluumaadku gacan ka geysanayo hagaajinta daaweynta. Sababtaas awgeed, shirkadaha caymiska caafimaadka badankood MA bixiyaan lacagta baaritaanka. Haddii AADAN lahayn ogaanshaha kolestaroolka sare ama cudurka wadnaha, baaritaankaan laguuguma talin doono adiga.

Qiyaasta caadiga ah waa qiyaastii 50 illaa 150 mg / dL.

Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabin karaan tijaabooyin kala duwan. Kala hadal adeeg bixiyahaaga macnaha natiijooyinka baaritaankaaga gaarka ah.

Natiijo aan caadi ahayn ayaa macnaheedu noqon karaa inaad dhiiggaaga ku jirto heerar dufan badan (dufan) ah. Erey caafimaad oo loogu talagalay tan waa hyperlipidemia.

Cilladaha kale ee laga yaabo inay la xiriiraan heerarka sare ee apoB100 waxaa ka mid ah cudurka xididdada atherosclerotic sida angina pectoris (xanuunka laabta ee ku dhaca firfircoonida ama walaaca) iyo wadna qabad.

Khataraha la xariira in dhiig lagaa qaado waa yar yihiin, laakiin waxaa ka mid noqon kara:

• Dhiigbax xad dhaaf ah
• Miyir beelid ama dareemid madax-wareer
• Hematoma (dhiigbax maqaarka hoostiisa)
• Infekshan (halis yar mar kasta oo maqaarku jabo)
• Daloollo badan si loo helo xididdada

Qiyaasaha Apolipoprotein ayaa laga yaabaa inay bixiyaan faahfaahin dheeraad ah oo ku saabsan halista cudurka wadnaha, laakiin qiimaha dheeraadka ah ee baaritaankaan ee ka baxsan xuubka dheecaanka lama yaqaan.

ApoB100; Apoprotein B100; Hypercholesterolemia - apolipoprotein B100

• Baaritaanka dhiigga

Fazio S, Linton MF. Shuruucda iyo nadiifinta borotiinada ku jira maadada apolipoprotein B. Gudaha: Ballantyne CM, ed. Lipidology Clinical: Wehel u ah Braunwald Cudurka Wadnaha. 2aad ed. Philadelphia, PA: Elsevier; 2015: cutubka 2.

Genest J, Libby P. Dhibaatooyinka Lipoprotein iyo cudurada wadnaha. Gudaha: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Cudurka Wadnaha ee Braunwald: Buugga Buugta Daawada Wadnaha iyo Xididdada. 11aad. Philadelphia, PA: Elsevier; 2019: cutubka 48.

Remaley AT, Dayspring TD, Warnick GR. Lipids, lipoproteins, apolipoproteins, iyo waxyaalaha kale ee halista wadnaha. Gudaha: Rifai N, ed. Tietz Textbook ee Kiimikada Caafimaadka iyo Cilad-baarista Molecular. 6aad ed. St Louis, MO: Elsevier; 2018: cutubka 34.

Robinson JG. Cilladaha dheef-shiid kiimikaadka. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 26aad. Philadelphia, PA: Elsevier; 2020: cutubka 195.