Imtixaanka CPK isoenzymes

Tijaabada loo yaqaan 'creatine phosphokinase (CPK) isoenzymes' ayaa lagu cabiraa noocyada kala duwan ee CPK ee dhiiga ku jira. CPK waa enzyme laga helo inta badan wadnaha, maskaxda, iyo murqaha lafaha.

Sambal dhiig ayaa loo baahan yahay. Tan waxaa laga qaadi karaa xididka. Baaritaanka waxaa loo yaqaan 'venipuncture'.

Haddii aad ku jirto cisbitaalka, baaritaankaan waxaa lagu soo celin karaa in ka badan 2 ama 3 maalmood. Sare u kac weyn ama hoos u dhac wadarta guud ee CPK ama istiraatiijiyada 'CPK isoenzymes' ayaa ka caawin kara bixiyaha xanaanada caafimaadkaaga inuu ogaado xaaladaha qaarkood.

Looma baahna diyaarin gaar ah kiisaska badankood.

U sheeg daryeel bixiyahaaga dhammaan daawooyinka aad qaadato. Daawooyinka qaarkood waxay faragelin ku sameyn karaan natiijooyinka baaritaanka. Daawooyinka kordhin kara cabirka CPK waxaa ka mid ah kuwan soo socda:

• Khamriga
• Amphotericin B
• Suuxdinta qaarkood
• Kokain
• Daawada fibra
• Statins
• Steroids, sida dexamethasone

Liiskani ma aha mid loo wada dhan yahay.

Waxaad dareemi kartaa xanuun yar markii irbadda la gelinayo si dhiig looga qaado. Dadka qaarkiis waxay dareemaan oo keliya dharbaaxo ama dareemid xaniin. Ka dib, waxaa jiri kara xoogaa wax garaaca.

Tijaabadani waxaa la sameeyaa haddii tijaabada CPK ay muujiso in guud ahaan heerkaaga CPK uu sarreeyo. Tijaabada CPK isoenzyme waxay kaa caawin kartaa helitaanka isha saxda ah ee unugyada dhaawacan.

CPK wuxuu ka samaysan yahay saddex walxood oo waxyar ka yara duwan:

• CPK-1 (sidoo kale loo yaqaan CPK-BB) waxaa laga helaa inta badan maskaxda iyo sambabaha
• CPK-2 (sidoo kale loo yaqaan CPK-MB) waxaa laga helaa inta badan wadnaha
• CPK-3 (sidoo kale loo yaqaan CPK-MM) waxaa laga helaa inta badan murqaha lafaha

Heerarka caadiga ka sarreeya ee caadiga ah ee CPK-1:

Sababtoo ah CPK-1 waxaa laga helaa inta badan maskaxda iyo sanbabada, dhaawaca labadaas meelood midkood wuxuu kordhin karaa heerarka CPK-1. Kordhinta heerarka CPK-1 waxaa laga yaabaa inay ugu wacan tahay:

• Kansarka maskaxda
• Dhaawaca maskaxda (nooc kasta oo dhaawac ah oo ay ku jiraan, istaroog, ama dhiig bax maskaxda)
• Daaweynta korantada
• Xanuun sambabeed
• Suuxdin

Heerarka caadiga ka sarreeya ee caadiga ah ee CPK-2:

Heerarka CPK-2 waxay sare u kacaan 3 illaa 6 saacadood kadib wadno qabad. Haddii uusan jirin waxyeello kale oo muruqa wadnaha ah, heerku wuxuu sarreeyaa 12 illaa 24 saacadood wuxuuna ku soo laabanayaa caadi 12 illaa 48 saacadood ka dib dhimashada unugyada.

Kordhinta heerarka CPK-2 sidoo kale waxaa laga yaabaa inay sabab u tahay:

• Dhaawacyada korantada
• Qalliinka wadnaha (ujeedo ula kac ah shaqaalaha caafimaadka).
• Dhaawaca wadnaha (tusaale ahaan, shil gaari)
• Caabuq ku dhaca muruqa wadnaha badanaa waxaa sababa fayras (myocarditis)
• Qalitaanka furan

Heerarka caadiga ah ee CPK-3 ee caadiga ka sarreeya ayaa badiyaa ah calaamadaha dhaawaca muruqa ama murqaha murugada. Waxaa laga yaabaa inay sabab u yihiin:

• Burbur dhaawacyada
• Waxyeellada muruqyada daroogada ama dhaqaaq la'aanta muddo dheer (rhabdomyolysis)
• Kala-baxa murqaha
• Myositis (barar murqaha lafaha)
• Helitaanka irbado badan oo muruqa ah
• Tijaabinta dhawaanta iyo muruqyada dhawaanta (electromyography)
• Suuxdintii ugu dambeysay
• Qalliin dhowaan dhacay
• Jimicsi culus

Caqabadaha saameyn ku yeelan kara natiijooyinka baaritaanka waxaa ka mid ah kateetarka wadnaha, cirbadaha muruqyada, qalliin dhowaan, iyo jimicsi xoog leh iyo muddo dheer ama dhaqdhaqaaq la'aan.

Imtixaanka Isoenzyme ee xaaladaha gaarka ah wuxuu ku saabsan yahay 90% sax ah.

Creatine fosfokinase - isoenzymes; Creatine kinase - isoenzymes; CK - isoenzymes; Wadne qabad - CPK; Burburin - CPK

• Baaritaanka dhiigga

Anderson JL. Qaybta St sare uqaadida wadnaha iyo myocardial infakshanka ba'an. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 25aad. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 73.

Marshall WJ, Day A, Lapsley M. Plasma borotiinka iyo enzymes. Gudaha: Marshall WJ, Day A, Lapsley M, eds. Chemistry Clinical. 8aad ed. Philadelphia, PA: Elsevier; 2017: cutubka 16.

Nagaraju K, Gladue HS, Lundberg IE. Cudurrada caabuqa ee muruqyada iyo myopathies kale. Gudaha: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Kelley iyo Firestein's Buugga Buugga Rheumatology. 10aad ed. Philadelphia, PA: Elsevier Saunders; 2017: cutubka 85.

Selcen D. Cudurada muruqyada. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 25aad. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 421.