Catecholamines - kaadi

Catecholamines waa kiimikooyin ay sameeyeen unugyada neerfaha (oo ay ku jiraan maskaxda) iyo qanjirka 'adrenal gland'.

Noocyada ugu waaweyn ee kaateegalamines waa dopamine, norepinephrine, iyo epinephrine. Kiimikooyinkani waxay u kala baxaan qaybo kale, kuwaas oo jidhkaaga uga tagaya kaadidaada.

Tijaabo kaadi ayaa la sameyn karaa si loo cabiro heerka catecholamines ee jirkaaga. Tijaabooyin kaadi oo gooni ah ayaa loo samayn karaa si loo cabbiro walxaha la xiriira.

Katecholamines sidoo kale waxaa lagu cabbiri karaa dhiig baaris.

Tijaabadan, waa inaad kaadidaada ku ururisaa boorso gaar ah ama weel markasta oo aad kaadido 24-saacadood.

• Maalinta 1aad, ku kaadi kaadi musqusha markii aad subaxa hore ka kacdid oo aad iska tuurtid kaadidaas.
• Kaadida weelka gaarka ah mar kasta oo aad musqusha isticmaasho 24ka saacadood ee soo socda. Ku hay qaboojiyaha ama meel qabow inta lagu jiro muddada ururinta.
• Maalinta 2, ku kaadi kaadi weelka subaxa labaad mar kale markaad toosto.
• Ku calaamade weelka magacaaga, taariikhda, waqtiga dhammaystirka, kuna soo celi sidii lagu faray.

Ilmaha yar, si fiican u maydh aagga ay kaadidu ka baxdo jirka.

• Fur boorsada kaadida lagu uruuriyo (bac balaastik ah oo warqad xabag leh ku leh dhinac dhinac).
• Ragga, guska oo dhan ku rid boorsada oo dhejiska ku dheji maqaarka.
• Dumar, bacda dul saar faruuryaha faruurta
• Xafaayad sidii caadiga ahayd bacda la hubiyey.

Nidaamkani wuxuu qaadan karaa xoogaa isku day ah. Ilmaha firfircoon wuxuu dhaqaajin karaa bacda taasoo keeneysa in kaadi ay gasho xafaayadda.

Hubi canugga badiyaa oo beddel bacda kadib markii uu canuggu ku kaadiyo. Kaadida kaadida bacda ku shub weelka uu ku siinayo daryeel caafimaad bixiyahaaga.

U gee sambalka shaybaarka ama bixiyahaaga sida ugu dhakhsaha badan ee suurtogalka ah.

Cadaadiska iyo jimicsiga culus ayaa saameyn ku yeelan kara natiijooyinka baaritaanka.

Cunnooyinka qaar waxay ku kordhin karaan kaadida catecholamines-kaaga. Waxaa laga yaabaa inaad u baahato inaad iska ilaaliso cuntooyinka iyo cabbitaannada soo socda dhowr maalmood baaritaanka ka hor:

• Mooska
• Shukulaatada
• Miraha liinta
• Kookaha
• Kafee
• Liisanka
• Shaah
• Vanilii

Daawooyin badan ayaa faragelin kara natiijooyinka baaritaanka.

• Bixiyahaaga ayaa kuu sheegi doona haddii aad u baahan tahay inaad joojiso qaadashada wax daawooyin ah ka hor baaritaankaan.
• HA JOOJIN ama ha beddelin dawooyinkaaga adiga oo aan marka hore la hadlin takhtarkaaga.

Tijaabadu waxay ku lug leedahay oo keliya kaadida caadiga ah, mana jiraan wax dhib ah.

Baaritaanka badanaa waxaa loo sameeyaa si loo ogaado burooyinka qanjidhada adrenal ee loo yaqaan pheochromocytoma. Waxaa sidoo kale loo isticmaali karaa in lagu baaro neuroblastoma. Heerarka kaadi-catecholamine-ka ayaa ku badan dadka badankood ee qaba neuroblastoma.

Tijaabada kaadida ee catecholamines ayaa sidoo kale loo isticmaali karaa in lagula socdo kuwa hela daaweynta xaaladahan.

Dhamaan kaateegalamines-ka waxaa loo kala jajabiyaa walxo aan firfircooneyn oo ka muuqda kaadida:

• Dopamine wuxuu noqdaa homovanillic acid (HVA)
• Norepinephrine wuxuu noqdaa normetanephrine iyo vanillylmandelic acid (VMA)
• Epinephrine wuxuu noqdaa metanephrine iyo VMA

Qiyamyada caadiga ah ee soo socdaa waa xaddiga walaxda laga helo kaadida muddo 24-saac ah:

• Dopamine: 65 illaa 400 microgram (mcg) / 24 saac (420 ilaa 2612 nmol / 24 saac)
• Epinephrine: 0.5 illaa 20 mcg / 24 saac
• Metanephrine: 24 ilaa 96 mcg / 24 saac (sheybaarada qaarkood waxay siiyaan inta udhaxeysa 140 ilaa 785 mcg / 24 saac)
• Norepinephrine: 15 illaa 80 mcg / 24 saac (89 illaa 473 nmol / saacadaha 24)
• Normetanephrine: 75 illaa 375 mcg / 24 saac
• Wadarta kaadida catecholamines: 14 ilaa 110 mcg / 24 saac
• VMA: 2 illaa 7 miligram (mg) / 24 saac (10 illaa 35 mcmol / 24 saac)

Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Kala hadal adeeg bixiyahaaga macnaha natiijooyinka baaritaankaaga gaarka ah.

Tusaalooyinka kor ku xusan waxay muujinayaan cabirka guud ee natiijooyinka imtixaanadan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabin karaan tijaabooyin kala duwan.

Heerarka sare ee kaadida catecholamines ee kaadida ayaa tilmaami kara:

• Walaac daran
• Ganglioneuroblastoma (aad dhif u ah)
• Ganglioneuroma (aad dhif u ah)
• Neuroblastoma (dhif)
• Pheochromocytoma (dhif)
• Cadaadis daran

Baaritaanka waxaa sidoo kale loo samayn karaa:

• Neoplasia endocrine badan (MEN) II

Ma jiraan wax khatar ah.

Dhowr cunno iyo daroogo, iyo sidoo kale dhaqdhaqaaqa jirka iyo culeyska fekerka, ayaa saameyn ku yeelan kara sax ahaanta baaritaankaan.

Dopamine - baaritaanka kaadida; Epinephrine - baaritaanka kaadida; Adrenalin - tijaabada kaadida; Kaadi-metanephrine; Normetanephrine; Norepinephrine - tijaabada kaadida; Katecholamines kaadida; VMA; HVA; Metanephrine; Homovanillic acid (HVA)

• Maqaarka kaadi mareenka
• Mareenka kaadi mareenka
• Tijaabada kaadida Catecholamine

Guber HA, Farag AF. Qiimeynta shaqada endocrine. Gudaha: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis iyo Maareynta Hababka Shaybaarka. 23aad ed. St Louis, MO: Elsevier; 2017: cutubka 24.

Dhalinyarada WF. Adrenal medulla, catecholamines, iyo pheochromocytoma. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 25aad. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 228.