Daaweynta xididdada dhiigga

Daaweynta Thrombolytic waa adeegsiga daroogada si loo kala jaro ama loo kala diro xinjirowga dhiigga, taas oo ah sababta ugu weyn ee wadno qabadka iyo istaroogga labadaba.

Daawooyinka dhiig-karka loo yaqaan 'Thrombolytic' ayaa loo oggol yahay daaweynta degdegga ah ee istaroogga iyo wadno qabadka. Daawada ugu badan ee loo isticmaalo daweynta thrombolytic waa unugyada plasminogen activator (tPA), laakiin daawooyinka kale waxay sameyn karaan isla wax.

Fikrad ahaan, waa inaad heshaa daawooyinka xinjirowga ah 30ka daqiiqo ee ugu horreeya ka dib markaad timaado isbitaalka si loogu daaweeyo.

WEERARADA QALBIGA

Xinjirowga dhiiggu wuxuu xidhmayaa xididdada wadnaha. Tani waxay sababi kartaa wadno-qabad, marka qayb ka mid ah muruqyada wadnuhu dhinto sababo la xiriira la'aanta oksijiin dhiigga lagu dhiibo.

Thrombolytics waxay ku shaqeysaa iyadoo si dhakhso leh u baabi'isa xinjir weyn. Tani waxay gacan ka geysaneysaa dib u bilowga socodka dhiigga ee wadnaha wuxuuna caawiyaa kahortagga dhaawaca muruqa wadnaha. Thrombolytics-ka ayaa joojin kara wadno-qabad haddii kale weynaan lahaa ama u dhiman kara. Natiijooyinka ayaa ka sii fiican haddii aad ku hesho dawo dhiig-yaqaanka muddo 12 saacadood gudahood ah ka dib marka wadnuhu istaago. Laakiin daaweynta ugu dhakhsaha badan ayaa bilaabmaysa, natiijooyinka ayaa ka sii fiicnaanaya.

Daroogadu waxay dib u soo celisaa xoogaa socodka dhiigga ee wadnaha dadka badankood. Si kastaba ha noqotee, socodka dhiiggu wuxuu noqon karaa mid gebi ahaanba caadi ah waxaana jiri kara qadar yar oo muruq ah oo dhaawacmay. Daaweyn dheeri ah, sida kateetarka wadnaha oo leh angioplasty iyo stenting, ayaa loo baahan karaa.

Bixiyahaaga daryeel caafimaad ayaa sal u noqon doona go'aamada ku saabsan in lagu siiyo daawo dhiig-xinjirowga wadnaha istaaga arrimo badan. Arrimahan waxaa ka mid ah taariikhdaada xanuunka laabta iyo natiijooyinka baaritaanka ECG.

Waxyaabaha kale ee loo isticmaalo in lagu go'aamiyo haddii aad u sharraxan tahay xinjirowga dhiigga waxaa ka mid ah:

• Da'da (dadka waayeelka ah waxay halis dheeraad ah ugu jiraan dhibaatooyin)
• Galmada
• Taariikhda caafimaadka (oo ay ku jiraan taariikhdaada wadno xanuun hore, sonkorow, dhiig kar hoose, ama garaaca wadnaha oo kordhay)

Guud ahaan, thrombolytics lama siin karo haddii aad leedahay:

• Dhaawac madaxa dhawaan ka soo gaadhay
• Dhibaatooyinka dhiig-baxa
• Boogaha dhiig baxa
• Uurka
• Qalliin dhowaan dhacay
• Qaado daawooyinka khafiifiya dhiigga sida Coumadin
• Murugo
• Dhiig kar aan la xakamayn (daran)

DHALO

Inta badan istaroog waxaa sababa marka xinjirowga dhiiggu u wareego xididdada dhiigga ee maskaxda oo xannibma socodka dhiigga ee aaggaas. Istaroogyada noocan oo kale ah (istaroogyada ischemic), thrombolytics ayaa loo isticmaali karaa inay ka caawiso kala-goynta xinjirta si dhakhso leh. Siinta trombolytics 3 saacadood gudahood ee astaamaha ugu horreeya ee istaroogga waxay kaa caawin kartaa xaddidaadda dhaawaca istaroogga iyo naafanimada.

Go'aanka lagu siinayo daawada wuxuu ku saleysan yahay:

• Skaanka CT-ga maskaxda si loo hubiyo in wax dhiig bax ah uusan dhicin
• Baadhitaan jireed oo muujinaya istaroog muhiim ah
• Taariikhdaada caafimaad

Sida wadne qabadka, daroogada xinjirowga-milanka badiyaa lama siiyo haddii aad leedahay mid ka mid ah dhibaatooyinka kale ee caafimaad ee kor ku xusan.

Trombolytics-ka lama siiyo qof qaba istaroog oo ku lug leh dhiig-baxa maskaxda. Waxay uga sii dari karaan istaroogga iyaga oo keenaya dhiig bax badan.

HALIS

Dhiigbaxu waa halista ugu badan. Waxay noqon kartaa nafta halis gelinaysa.

Dhiigbax yar oo ka yimaada ciridka ama sanka ayaa ku dhici kara ugu yaraan 25% dadka qaata daroogada. Dhiigbaxidda maskaxda waxay dhacdaa ugu yaraan 1% waqtiga. Khatartani waxay lamid tahay bukaan socodka istaroogga iyo wadne qabadkaba.

Haddii thrombolytics loo arko inay khatar badan yihiin, daaweynta kale ee suurtagalka ah ee xinjirooyinka keena istaroog ama wadne qabad waxaa ka mid ah:

• Ka goynta xinjirowga (thrombectomy)
• Nidaam lagu furayo xididdada dhiigga ee cidhiidhiga ah ama xidhan ee dhiigga siiya wadnaha ama maskaxda

LA Xiriir Bixiyaha DARYEEL CAAFIMAAD AMA WAC 911

Wadne qabad iyo istaroog waa xaalado caafimaad oo deg deg ah. Daaweynta ugu dhakhsaha badan ee loo yaqaan 'thrombolytics' ayaa bilaabmaysa, fursad fiican ayey u leedahay natiijada wanaagsan.

Dhaqdhaqaaqa unugyada plasminogen; TPA; Alteplase; Dib u cusbooneysiin; Tenecteplase; Dareem wakiilka thrombolytic; Wakiilada kala-goynta dharka; Daaweynta kufsiga; Faalig - thrombolytic; Wadne qabad - thrombolytic; Xinjirowga daran - thrombolytic; Xinjirowga dhiigga - thrombolytic; Lanoteplase; Staphylokinase; Streptokinase (SK); Urokinase; Stroke - daaweynta xididka dhiigga; Wadna qabad - daaweynta xididka dhiigga ee dhiigga lagu shubo; Faalig - thrombolysis; Wadne qabad - thrombolysis; Cudurka 'myocardial infarction' - thrombolysis

• Faalig
• Thrombus
• Ku dhaji jeexjeexa wadnaha myocardial ECG

Bohula EA, Morrow DA. Cudurka 'myocardial infarction' ST-elevation: maareynta. Gudaha: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Cudurka Wadnaha ee Braunwald: Buugga Buugta Daawada Wadnaha iyo Xididdada. 11aad. Philadelphia, PA: Elsevier; 2019: cutubka 59.

Crocco TJ, Meurer WJ. Faalig Gudaha: Walls RM, Hockberger RS, Gausche-Hill M, eds. Daawada Degdega ah ee Rosen: Fikradaha iyo Tababarka Caafimaadka. 9aad. Philadelphia, PA: Elsevier; 2018: cutubka 91.

Jaffer IH, Weitz JI. Dawooyinka lidka ku ah jirka. Gudaha: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Mabaadi'da Aasaasiga ah iyo Tababarka. 7aad ed. Philadelphia, PA: Elsevier; 2018: cutubka 149.

O'Gara PT, Kushner FG, Ascheim DD, iyo al. Tilmaamaha 2013 ACCF / AHA ee loogu talagalay maareynta xakamaynta miyokardial ee ST-elevation: warbixin ka socota Kuleejka Aasaasiga ah ee Wadnaha iyo Wadnaha ee Ururka Wadnaha ee Mareykanka ee Tilmaamaha Tababarka. Wareegga. 2013; 127 (4): 529-555. PMID: 23247303 pubmed.ncbi.nlm.nih.gov/23247303/.