Qoraa: William Ramirez
Taariikhda Abuurista: 16 Setembar 2021
Taariikhda Cusboonaysiinta: 1 Abriil 2025
Anonim
What Doctors are saying about CBD? | Cannabidiol
Dareemoleyad: What Doctors are saying about CBD? | Cannabidiol

Qanacsan

Cannabidiol waa kiimiko ku jirta dhirta Cannabis sativa, oo sidoo kale loo yaqaan marijuana ama hemp. In ka badan 80 kiimikooyin ah, oo loo yaqaan 'cannabinoids', ayaa lagu aqoonsaday dhirta Cannabis sativa. Iyadoo delta-9-tetrahydrocannabinol (THC) ay tahay maaddada ugu weyn ee firfircoon ee marijuana, cannabidiol sidoo kale waxaa laga helaa hemp, oo ay ku jiraan kaliya qaddar aad u yar oo ah THC.

Meelmarinta Sharciga Beeraha ee 2018 ayaa sharci ka dhigay in lagu iibiyo alaabada hemp iyo hemp ee Mareykanka Laakiin taasi micnaheedu maahan in dhammaan alaabada cannabidiol ee hemp-ka laga soo qaaday ay sharci yihiin. Maaddaama cannabidiol loo bartay sidii daroogo cusub, sharci ahaan laguma dari karo cuntooyinka ama nafaqada dheeraadka ah. Sidoo kale, cannabidiol laguma dari karo waxyaabaha lagu suuq geeyo sheegashooyinka daaweynta. Cannabidiol waxaa lagu dari karaa oo keliya alaabada "qurxinta" kaliya waa haddii ay ka kooban tahay wax ka yar 0.3% THC. Laakiin weli waxaa jira alaabooyin loo calaamadeeyay inay yihiin nafaqeeyeyaal suuq ah oo ay ku jiraan cannabidiol. Qaddarka cannabidiol ee ku jira alaabtan marwalba looma sheego si sax ah calaamadda sheyga.

Cannabidiol waxaa badanaa loo isticmaalaa qalalaasaha suuxdinta (suuxdinta). Waxaa sidoo kale loo isticmaalaa walwalka, xanuunka, cilladda muruqyada ee loo yaqaan dystonia, cudurka Parkinson, cudurka Crohn, iyo xaalado kale oo badan, laakiin ma jiraan wax caddeyn cilmi ah oo wanaagsan oo lagu taageerayo adeegsigaas.

Daawooyinka Dabiiciga ah ee Xogta Dhamaystiran waxay qiimeysaa waxtarka ku saleysan caddeynta sayniska iyadoo loo eegayo cabirka soo socda: Wax ku ool ah, Suurta gal ah inuu wax ku ool yahay, suurtagal tahay wax ku ool ah, macquul ahaan waxtar la'aan, suurtagal ahaan waxtar la'aan, waxtar la'aan, iyo caddayn ku filan oo lagu qiimeeyo.

Qiimeynta waxtarka ee CANNABIDIOL (CBD) waa sida soo socota:


Waxtar u leh ...

  • Qalalaase qalal (suuxdin). Badeecad gaar ah oo loo yaqaan 'cannabidiol' (Epidiolex, GW Pharmaceuticals) ayaa la muujiyey inay yareyneyso suuxdinta dadka waaweyn iyo carruurta leh xaalado kala duwan oo lala xiriirinayo qalal. Badeecadani waa dawo dhakhtar qoro oo lagu daaweeyo qallalka uu sababo xanuunka loo yaqaan 'Dravet syndrome', 'Lennox-Gastaut syndrome', ama isku-darka isku-buuqa maskaxda. Waxaa sidoo kale la muujiyey inay yareyneyso qallalka dadka qaba cudurka Sturge-Weber, febrile infekshinka la xariira suuxdinta (FIRES), iyo cilladaha hiddo-wadaha ee gaarka ah ee sababa maskaxda suuxdinta. Laakiin looma oggola in lagu daaweeyo noocyada kale ee qalal. Badeecadan waxaa badanaa la qaataa iyada oo lagu daro dawooyinka caadiga ah ee ka-hortagga qalalaasaha. Qaar ka mid ah waxyaabaha loo yaqaan 'cannabidiol' ee lagu sameeyo shaybaarka ayaa sidoo kale lagu baranayaa suuxdin. Laakiin cilmi-baaristu way xadidan tahay, oo alaabooyinkaas midkoodna looma oggola dawooyinka loo qoro.

Cadeymo aan ku filneyn in lagu qiimeeyo wax ku oolnimada ...

  • Nooc ka mid ah cudurada mindhicirka ee caabuqa (Crohn disease). Cilmibaarista hore waxay muujineysaa in qaadashada cannabidiol aysan yareynin waxqabadka cudurka ee dadka waaweyn ee qaba cudurka Crohn.
  • Sonkorowga. Cilmi-baaris hore waxay muujisay in qaadashada cannabidiol aysan hagaajinaynin qaan-gaadhka kontoroolka gulukooska dhiigga dadka waaweyn ee qaba nooca sonkorowga 2.
  • Cilad dhaqdhaqaaq oo lagu calaamadeeyay foosha muruqyada aan qasabka ahayn (dystonia). Ma cadda haddii cannabidiol uu faa'iido u leeyahay dystonia.
  • Xaalad la iska dhaxlo oo lagu calaamadeeyay naafonimo waxbarasho (jilicsanaan - X syndrome). Cilmi-baarista hore waxay soo jeedineysaa in la adeegsado 'cannabidiol gel' laga yaabo inay yareyso walwalka isla markaana ay hagaajiso dabeecadda carruurta leh jilicsanaanta X syndrome.
  • Xaalad ah in xubin ka mid ah jirka lagu tallaalo ay weeraraan jirka (cudurada ka soo horjeedka martida ama martida loo yahay ama GVHD). Cudurka 'Graft-versus-host disease' waa dhibaato ka dhalan karta ka dib tallaalka dhuuxa lafta. Daraasad hore ayaa lagu ogaaday in qaadashada cannabidiol maalin kasta laga bilaabo 7 maalmood ka hor tallaalka dhuuxa lafta oo la sii wado 30 maalmood ka dib marka la beddelo ka dib waxay dheereyn kartaa waqtiga ay qaadanayso qofku inuu ku horumariyo GVHD.
  • Cillad maskaxeed oo la iska dhaxlo oo saameysa dhaqdhaqaaqa, shucuurta, iyo fikirka (cudurka Huntington). Daraasad hore waxay muujineysaa in qaadashada cannabidiol maalin kasta aysan hagaajinaynin calaamadaha cudurka Huntington.
  • Cudurka 'sclerosis' (MS). Daraasad hore waxay soo jeedineysaa in la isticmaalo buufinta cannabidiol ee carrabka hoostiisa laga yaabo inay hagaajiso xanuunka iyo murqaha oo adkaada dadka qaba MS.
  • Ka noqoshada heroin, morphine, iyo daroogooyinka kale ee opioid. Cilmibaarista hore waxay muujineysaa in qaadashada cannabidiol 3 maalmood ay yareyn karto jahwareerka iyo welwelka dadka qaba cudurka loo yaqaan 'heroin use disorder'.
  • Cudurka Parkinson. Daraasad hore waxay muujisay in cannabidiol laga yaabo inuu yareeyo walwalka iyo astaamaha cudurka maskaxda ee dadka qaba cudurka Parkinson.
  • Schizophrenia. Cilmi-baarista hore waxay soo jeedineysaa in qaadashada cannabidiol ay hagaajiso astaamaha iyo ladnaanta dadka qaba shisoofrani.
  • Joojinta sigaarka. Cilmibaaristii ugu horreysay waxay soo jeedineysaa in neefsashada cannabidiol ee neefta hal toddobaad ay yareyn karto tirada sigaarka ay cabaan kuwa caba sigaarka isku dayaya inay joojiyaan.
  • Nooc walaac ah oo lagu calaamadeeyay cabsi ka jirta qaar ama dhammaan goobaha bulshada (cilladda bulshada ee walwalka). Daraasad hore waxay muujisay in cannabidiol laga yaabo inuu wanaajiyo welwelka dadka qaba cilladan. Laakiin ma cadda haddii ay ka caawineyso yareynta walwalka inta lagu jiro khudbadaha dadweynaha.
  • Koox xaalado xanuun leh oo saameeya daamanka iyo muruqyada (cilladaha ku-meel-gaadhka ah ama TMD). Daraasad hore waxay muujisay in saliid ay kujirto cannabidiol maqaarka ay yareyn karto xanuunka dadka qaba TMD.
  • Dhaawaca neerfaha ee gacmaha iyo cagaha (neuropathy peripheral).
  • Cudurka laba-cirifoodka.
  • Hurdo la'aan.
  • Xaaladaha kale.
Cadeymo badan ayaa loo baahan yahay si loo qiimeeyo waxtarka cannabidiol ee adeegyadan.

Cannabidiol wuxuu saameyn ku leeyahay maskaxda. Sababta saxda ah ee waxyeeladani ma cadda. Si kastaba ha noqotee, cannabidiol waxay umuuqataa inay kahortageyso burburka kiimikada maskaxda kujirta ee saameysa xanuunka, niyadda, iyo shaqada maskaxda. Kahortaga burburka kiimikadan iyo kordhinta heerarkiisa dhiiga waxay umuuqataa inay yareyneyso astaamaha nafsiyeed ee laxiriira xaaladaha sida shisoofrani. Cannabidiol ayaa sidoo kale laga yaabaa inuu xannibo qaar ka mid ah dhibaatooyinka nafsaaniga ah ee delta-9-tetrahydrocannabinol (THC). Sidoo kale, cannabidiol wuxuu umuuqdaa inuu yareynayo xanuunka iyo walwalka.

Markii afka lagaa qaado: Cannabidiol waa BADBAADO KU SAABSAN marka afka lagaa qaado ama carrabka hoostiisa lagu buufiyo si haboon. Cannabidiol oo qaadasho ah illaa 300 mg maalintii ayaa afka si ammaan ah looga qaataa illaa 6 bilood. Qiyaaso badan oo ah 1200-1500 mg maalin kasta ayaa si nabdoon afka looga qaatay ilaa 4 usbuuc. Daawada daawada loo yaqaan 'cannabidiol' (Epidiolex) ayaa loo oggol yahay in lagu qaato afka qiyaas ahaan illaa 25 mg / kg maalin kasta. Buufinta Cannabidiol ee carrabka lagu mariyo ayaa loo isticmaalay qiyaaso ah 2.5 mg ilaa 2 toddobaad.

Qaar ka mid ah waxyeelooyinka la soo sheegay ee cannabidiol waxaa ka mid ah afka oo qalala, cadaadis dhiig oo hooseeya, madax xanuun fudud, iyo lulmo. Calaamadaha dhaawaca beerka ayaa sidoo kale lagu soo warramey bukaanada qaar, laakiin tani way ku yar tahay.

Marka la mariyo maqaarka: Ma jiro macluumaad ku filan oo la isku halleyn karo oo lagu ogaanayo haddii cannabidiol uu badbaado leeyahay ama waxa ay saameynadu noqon karto.

Taxaddarrada gaarka ah & digniinta:

Uurka iyo nuujinta: Cannabidiol waa Suuragal AAN LAHAYN inaad isticmaasho haddii aad uur leedahay ama aad naas nuujinayso. Waxyaabaha laga helo Cannabidiol waxaa lagu sumoobi karaa waxyaabo kale oo waxyeelo u keeni kara uurjiifka ama dhallaanka. Joog dhinaca aaminka ah iskana ilaali isticmaalka.

Caruurta: Daawada daawada loo yaqaan 'cannabidiol' (Epidiolex) waa BADBAADO KU SAABSAN markii afka lagaa qaado qaadasho ilaa 25 mg / kg maalin kasta. Badeecadani waa la oggol yahay in loo isticmaalo carruurta qaarkood ee jira 1 sano iyo wixii ka weyn.

Cudurka beerka: Dadka qaba cudurka beerka waxay u baahan karaan inay isticmaalaan qadar yar oo ah cannabidiol marka loo eego bukaanka caafimaadka qaba.

Cudurka Parkinson: Qaar ka mid ah cilmi baarista hore waxay soo jeedinayaan in qaadashada qiyaaso badan oo cannabidiol ah ay ka dhigeyso dhaqdhaqaaqa murqaha iyo gariir ka sii dara dadka qaar ee qaba cudurka Parkinson.

Dhexdhexaad
Ka taxaddar isku-dhafkan.
Brivaracetam (Briviact)
Brivaracetam jirku wuu beddelaa oo burburiyaa. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee jidhku u burburiyo brivaracetam. Tani waxay kordhin kartaa heerarka brivaracetam ee jirka.
Carbamazepine (Tegretol)
Carbamazepine jidhku wuu beddelaa oo burburiyaa. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee jidhku u burburiyo carbamazepine. Tani waxay kordhin kartaa heerarka carbamazepine ee jirka waxayna kordhin kartaa waxyeellooyinkeeda.
Clobazam (Onfi)
Clobazam waxaa bedelay oo burburiyey beerka. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u burburiyo clobazam. Tani waxay kordhin kartaa saameynta iyo dhibaatooyinka soo raaca ee clobazam.
Eslicarbazepine (Aptiom)
Jirka 'Eslicarbazepine' ayaa isbedelay oo jabiyey. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee jidhku u burburiyo eslicarbazepine. Tani waxay kordhin kartaa heerarka eslicarbazepine ee jirka qadar yar.
Everolimus (Zostress)
Everolimus waxaa bedelay oo jabiyey jirka. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee jidhku u burburo everolimus. Tani waxay kordhin kartaa heerarka everolimus ee jirka.
Lithium
Qaadashada qiyaaso badan oo cannabidiol ah waxay kordhin kartaa heerarka lithium. Tani waxay kordhin kartaa halista sunta lithium.
Daawooyinka beerka laga beddelay (Cytochrome P450 1A1 (CYP1A1) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, isticmaalka cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka beddelo.

Daawooyinka qaar ee beerka badalay waxaa kamid ah chlorzoxazone (Lorzone) iyo theophylline (Theo-Dur, kuwa kale).
Daawooyinka laga beddelay beerka (Cytochrome P450 1A2 (CYP1A2) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, adeegsiga cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka lagu beddelo.

Daawooyinka qaar ee beerka badalay waxaa kamid ah amitriptyline (Elavil), haloperidol (Haldol), ondansetron (Zofran), propranolol (Inderal), theophylline (Theo-Dur, kuwa kale), verapamil (Calan, Isoptin, kuwa kale), iyo kuwa kale.
Daawooyinka beerka laga beddelay (Cytochrome P450 1B1 (CYP1B1) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, adeegsiga cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka lagu beddelo.

Daawooyinka qaar ee beerka badalay waxaa kamid ah theophylline (Theo-Dur, kuwa kale), omeprazole (Prilosec, Omesec), clozapine (Clozaril, FazaClo), progesterone (Prometrium, kuwa kale), lansoprazole (Prevacid), flutamide (Eulexin), oxaliplatin (Eloxatin) ), erlotinib (Tarceva), iyo kafeyn.
Daawooyinka beerka laga beddelay (Cytochrome P450 2A6 (CYP2A6) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, isticmaalka cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka beddelo.

Daawooyinka qaar ee beerka badalay waxaa kamid ah nikotiin, chlormethiazole (Heminevrin), coumarin, methoxyflurane (Penthrox), halothane (Fluothane), valproic acid (Depacon), disulfiram (Antabuse), iyo kuwa kale.
Daawooyinka beerka laga beddelay (Cytochrome P450 2B6 (CYP2B6) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, isticmaalka cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka beddelo.

Daawooyinka qaar ee beerka badalay waxaa kamid ah ketamiin (Ketalar), phenobarbital, orphenadrine (Norflex), secobarbital (Seconal), iyo dexamethasone (Decadron).
Daawooyinka ay beerka badaleen (Cytochrome P450 2C19 (CYP2C19) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, isticmaalka cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka lagu beddelo.

Daawooyinka qaar ee beerka badalay waxaa kamid ah proton pump inhibitors oo ay kamid yihiin omeprazole (Prilosec), lansoprazole (Prevacid), iyo pantoprazole (Protonix); diazepam (Valium); carisoprodol (Soma); nelfinavir (Viracept); iyo kuwa kale.
Daawooyinka ay beerka badaleen (Cytochrome P450 2C8 (CYP2C8) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, adeegsiga cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka lagu beddelo.
Daawooyinka qaar ee beerka badalay waxaa kamid ah amiodarone (Cordarone), carbamazepine (Tegretol), chloroquine (Aralen), diclofenac (Voltaren), paclitaxel (Taxol), repaglinide (Prandin) iyo kuwa kale.
Daawooyinka ay beerka badaleen (Cytochrome P450 2C9 (CYP2C9) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, adeegsiga cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka beddelo.

Daawooyinka qaar ee beerka badalay waxaa kamid ah daawooyinka nonsteroidal anti-inflammatory drugs (NSAIDs) sida diclofenac (Cataflam, Voltaren), ibuprofen (Motrin), meloxicam (Mobic), piroxicam (Feldene), iyo celecoxib (Celebrex); amitriptyline (Elavil); warfarin (Coumadin); glipizide (Glucotrol); losartan (Cozaar); iyo kuwa kale.
Daawooyinka beerka laga beddelay (Cytochrome P450 2D6 (CYP2D6) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, adeegsiga cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka beddelo.

Daawooyinka qaarkood ee beerka badalay waxaa kamid ah amitriptyline (Elavil), codeine, desipramine (Norpramin), flecainide (Tambocor), haloperidol (Haldol), imipramine (Tofranil), metoprolol (Lopressor, Toprol XL), ondansetron (Zofran), paroxetil ), risperidone (Risperdal), tramadol (Ultram), venlafaxine (Effexor), iyo kuwo kale.
Daawooyinka laga beddelay beerka (Cytochrome P450 3A4 (CYP3A4) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, isticmaalka cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka beddelo.

Daawooyinka qaar ee beerka badalay waxaa kamid ah alprazolam (Xanax), amlodipine (Norvasc), clarithromycin (Biaxin), cyclosporine (Sandimmune), erythromycin, lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox) (trigraen), fexof (Halcion), verapamil (Calan, Isoptin) iyo kuwa kale oo badan.
Daawooyinka ay beerka badaleen (Cytochrome P450 3A5 (CYP3A5) substrates)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Aragti ahaan, isticmaalka cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinka qaarkood. Kahor intaadan isticmaalin cannabidiol, kala hadal daryeel caafimaad bixiyahaaga haddii aad qaadato wax daawo ah oo beerka beddelo.

Daawooyinka qaar ee beerka badalay waxaa kamid ah testosterone, progesterone (Endometrin, Prometrium), nifedipine (Adalat CC, Procardia XL), cyclosporine (Sandimmune), iyo kuwa kale.
Daawooyinka beerka laga beddelay (Glucuronidated drugs)
Daawooyinka qaar beerka ayaa badala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u jajabiyo daawooyinka qaarkood. Qaadashada cannabidiol oo ay weheliso daawooyinka qaarkood ee beerku burburiyo waxay kordhin karaan saamaynta iyo dhibaatooyinka daawooyinkaas.
Daawooyinkaan qaarkood ee beerka badalay waxaa kamid ah acetaminophen (Tylenol, kuwa kale) iyo oxazepam (Serax), haloperidol (Haldol), lamotrigine (Lamictal), morphine (MS Contin, Roxanol), zidovudine (AZT, Retrovir), iyo kuwa kale.
Daawooyinka yareeya burburka daawooyinka kale ee beerka (Cytochrome P450 2C19 (CYP2C19) inhibitors)
Cannabidiol waxaa burburiyey beerka. Daawooyinka qaarkood waxay yareyn karaan sida ugu dhakhsaha badan ee beerku u burburo cannabidiol. Qaadashada cannabidiol oo ay weheliso daawooyinkan waxay kordhin kartaa saameynta iyo dhibaatooyinka soo raaca cannabidiol.
Daawooyinka qaar ee yareyn kara burburka cannabidiol ee beerka kujira waxaa kamid ah cimetidine (Tagamet), fluvoxamine (Luvox), omeprazole (Prilosec); ticlopidine (Ticlid), topiramate (Topamax), iyo kuwa kale.
Daawooyinka yareeya burburka daawooyinka kale ee beerka (Cytochrome P450 3A4 (CYP3A4) inhibitors)
Cannabidiol ayaa beerka jabiya. Daawooyinka qaarkood waxay yareyn karaan sida ugu dhakhsaha badan ee beerku u burburo cannabidiol. Qaadashada cannabidiol oo ay weheliso daawooyinkan waxay kordhin kartaa saameynta iyo dhibaatooyinka soo raaca cannabidiol.
Daawooyinka qaar ee yareyn kara sida ugu dhakhsaha badan ee beerku u burburo cannabidiol waxaa ka mid ah amiodarone (Cordarone), clarithromycin (Biaxin), diltiazem (Cardizem), erythromycin (E-mycin, Erythrocin), indinavir (Crixivan), ritonavir (Norvir), saquinavir (Fortovase) , Invirase), iyo kuwa kale oo badan.
Daawooyinka kordhiya burburka daawooyinka kale ee beerka (Cytochrome P450 3A4 (CYP3A4) inducers)
Cannabidiol waxaa burburiyey beerka. Daawooyinka qaarkood waxay kordhin karaan sida ugu dhakhsaha badan ee beerku u burburo cannabidiol. Qaadashada cannabidiol oo ay weheliso daawooyinkani waxay yareyn karaan saameynta cannabidiol.
Daawooyinkaas qaarkood waxaa ka mid ah carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), iyo kuwo kale.
Daawooyinka kordhiya burburka daawooyinka kale ee beerka (Soojiyeyaasha Cytochrome P450 2C19 (CYP2C19))
Cannabidiol waxaa burburiyey beerka. Daawooyinka qaarkood waxay kordhin karaan sida ugu dhakhsaha badan ee beerku u burburo cannabidiol. Qaadashada cannabidiol oo ay weheliso daawooyinkani waxay yareyn karaan saameynta cannabidiol.
Daawooyinka qaarkood ee kordhin kara burburka cannabidiol ee beerka waxaa ka mid ah carbamazepine (Tegretol), prednisone (Deltasone), iyo rifampin (Rifadin, Rimactane).
Methadone (Dolophine)
Methadone beerka ayaa jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee beerku u burburiyo methadone. Qaadashada cannabidiol oo ay weheliso methadone waxay kordhin kartaa saameynta iyo dhibaatooyinka soo raaca methadone.
Rufinamide (Banzel)
Rufinamide waa la beddelaa oo waa la jebiyaa jirka. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee jidhku u burburiyo rufinamide. Tani waxay kordhin kartaa heerarka rufinamide ee jirka qadar yar.
Daawooyinka daweynta (CNS depressants)
Cannabidiol wuxuu sababi karaa hurdo iyo lulmo. Daawooyinka keena hurdada waxaa loo yaqaan seddexyaal. Qaadashada cannabidiol oo ay weheliso daawooyinka suuxinta waxay sababi kartaa hurdo badan.

Daawooyinka dajinta qaarkood waxaa ka mid ah benzodiazepines, pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), thiopental (Pentothal), fentanyl (Duragesic, Sublimaze), morphine, propofol (Diprivan), iyo kuwo kale.
Sirolimus (Rapamune)
Sirolimus waxaa beddelay oo jebiyey jirku. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee jidhku u burburo sirolimus. Tani waxay kordhin kartaa heerarka sirolimus ee jirka.
Stiripentol (Diacomit)
Stiripentol jirka ayaa isbadala oo jajabiya. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee jidhku u burburiyo stiripentol. Tani waxay kordhin kartaa heerarka 'stiripentol' ee jirka waxayna kordhin kartaa waxyeellooyinkeeda.
Tacrolimus (Prograf)
Tacrolimus jirku wuu beddelaa oo jajabiyaa. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee jidhku u jajabiyo tacrolimus. Tani waxay kordhin kartaa heerarka tacrolimus ee jirka.
Topiramate (Tompamax)
Topiramate jirka waa la beddelay oo la jebiyey. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee jidhku u burburiyo Topiramate. Tani waxay kordhin kartaa heerarka Topiramate ee jirka qadar yar.
Qiimee
Valproic acid wuxuu sababi karaa dhaawaca beerka Qaadashada cannabidiol leh valproic acid waxay kordhin kartaa fursadda dhaawaca beerka. Cannabidiol iyo / ama valproic acid ayaa laga yaabaa inay u baahdaan in la joojiyo, ama qiyaasta loo baahdo in la yareeyo.
Warfarin
Cannabidiol wuxuu kordhin karaa heerarka warfarin, taas oo kordhin karta halista dhiig-baxa. Cannabidiol iyo / ama warfarin waxay u baahan karaan in la joojiyo, ama qiyaasta loo baahdo in la yareeyo.
Zonisamide
Zonisamide jirka ayaa isbadalay oo jebiyay. Cannabidiol wuu yarayn karaa sida ugu dhakhsaha badan ee jidhku u burburiyo zonisamide. Tani waxay kordhin kartaa heerarka zonisamide ee jirka qadar yar.
Dhirta iyo kaabayaasha leh astaamaha daweynta
Cannabidiol wuxuu sababi karaa hurdo ama lulmo. U isticmaalkeeda iyada oo ay weheliyaan geedo kale iyo waxyaabo dheeri ah oo isku saameyn ah waxay sababi kartaa hurdo badan. Qaar ka mid ah dhirtaas iyo kaabayaashaas waxaa ka mid ah calamus, California poppy, catnip, hops, Jamaican dogwood, kava, L-tryptophan, melatonin, sage, SAMe, St. John's wort, sassafras, skullcap, iyo kuwo kale.
Khamriga (Ethanol)
Qaadashada cannabidiol ee khamriga waxay kordhisaa xaddiga cannabidiol ee jirka nuugo. Tani waxay kordhin kartaa saameynta iyo dhibaatooyinka soo raaca cannabidiol.
Dufan iyo cuntooyin dufanku ku jiro
Qaadashada cannabidiol cunno dufan badan leh ama ugu yaraan ay ku jiraan xoogaa dufan ah, waxay kordhisaa xaddiga cannabidiol ee jirka nuugo. Tani waxay kordhin kartaa saameynta iyo dhibaatooyinka soo raaca cannabidiol.
Caano
Qaadashada cannabidiol ee caanaha waxay kordhisaa xaddiga cannabidiol ee jirka nuugo. Tani waxay kordhin kartaa saameynta iyo dhibaatooyinka soo raaca cannabidiol.
Qiyaasaha soo socda ayaa lagu bartay cilmi baarista sayniska:

DADKA WAAWEYN

Afka:
  • Suuxdinta: Daawada loo yaqaan 'cannabidiol' (Epidiolex) ayaa la isticmaalay. Qiyaasta bilowga ah ee lagu taliyay ee Lennox-Gastaut syndrome iyo Dravet syndrome waa 2.5 mg / kg laba jeer maalintii (5 mg / kg / day). Hal usbuuc kadib qiyaasta waa la kordhin karaa ilaa 5 mg / kg laba jeer maalintii (10 mg / kg / day). Haddii qofku uusan ka jawaabin qiyaastaas, ugu badnaan lagu taliyay waa 10 mg / kg laba jeer maalintii (20 mg / kg / day). Qiyaasta bilowga ah ee lagu talinayo isku-darka isku-xoqitaanka jirka waa 2.5 mg / kg laba jeer maalintii (5 mg / kg / maalin). Tan waxaa lagu kordhin karaa xilliyada usbuuclaha ah haddii loo baahdo, ugu badnaan 12.5 mg / kg laba jeer maalintii (25 mg / kg / day). Ma jiro caddayn saynis oo xoog leh oo ah in alaab aan cannabidiol ahayn oo aan qoris lahayn ay faa'iido u leedahay suuxdinta.
CARRUURTA

Afka:
  • Suuxdinta: Daawada loo yaqaan 'cannabidiol' (Epidiolex) ayaa la isticmaalay. Qiyaasta bilowga ah ee lagu taliyay ee Lennox-Gastaut syndrome iyo Dravet syndrome waa 2.5 mg / kg laba jeer maalintii (5 mg / kg / day). Hal usbuuc kadib qiyaasta waa la kordhin karaa ilaa 5 mg / kg laba jeer maalintii (10 mg / kg / day). Haddii qofku uusan ka jawaabin qiyaastaas, ugu badnaan lagu taliyay waa 10 mg / kg laba jeer maalintii (20 mg / kg / day). Qiyaasta bilowga ah ee lagu talinayo isku-darka isku-xoqitaanka jirka waa 2.5 mg / kg laba jeer maalintii (5 mg / kg / maalin). Tan waxaa lagu kordhin karaa xilliyada usbuuclaha ah haddii loo baahdo, ugu badnaan 12.5 mg / kg laba jeer maalintii (25 mg / kg / day). Ma jiro caddayn saynis oo xoog leh oo ah in alaab aan cannabidiol ahayn oo aan qoris lahayn ay faa'iido u leedahay suuxdinta.
2 - [(1R, 6R) -3-Methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl] -5-pentylbenzene-1,3-diol, CBD.

Si aad wax badan uga ogaato sida maqaalkan loo qoray, fadlan eeg Daawooyinka Dabiiciga ah ee Xogta Dhamaystiran habka.


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