Cirbadda Sarilumab

Qanacsan

• Kahor qaadashada duritaanka sarilumab,
• Cirbadda Sarilumab waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:

Cirbadda Sarilumab waxay yareyn kartaa awooddaada inaad la dagaallanto infekshinka waxayna kordhisaa halista aad ku qaadi karto infekshan daran, oo ay ku jiraan fangas daran, bakteeriyada, ama infekshannada ku faafa jirka oo dhan. Caabuqyadan waxaa laga yaabaa inay u baahan yihiin in lagu daweeyo isbitaal waxayna sababi karaan dhimasho. U sheeg dhakhtarkaaga haddii aad badanaa ku dhacdo nooc kasta oo infekshan ah ama haddii aad u malaynayso inaad hadda nooc cudur ah qabtid. Tan waxaa ka mid ah infekshannada yaryar (sida nabarrada furan ama nabarrada), infekshannada imanaya ama tagaya (sida nabarrada qabow), iyo infekshannada daba-dheeraada ee aan dhammaanayn. Sidoo kale u sheeg dhakhtarkaaga haddii aad qabtid ama waligaa aad qabtid sonkorow, fayraska difaaca jirka ee dadka (HIV), ama aad heshay cillad difaac la'aanta (AIDS), ama xaalad kasta oo kale oo saameysa nidaamkaaga difaaca. Sidoo kale waa inaad u sheegtaa dhakhtarkaaga haddii aad nooshahay, waligaa ma nooshahay, haddii aad u safartay aagagga sida dooxooyinka Ohio ama Mississippi halkaas oo infekshannada fungal ee daran ay ku badan yihiin. Weydii dhakhtarkaaga haddii aadan hubin in cudurradan ay ku badan yihiin aaggaaga. U sheeg dhakhtarkaaga haddii aad qaadanaysid daawooyin yareynaya howlaha nidaamka difaaca jirka sida kuwa soo socda: abatacept (Orencia); adalimumab (Humira); anakinra (Kineret); certolizumab pegol (Cimzia); etanercept (Enbrel); golimumab (Simponi); infliximab (Remicade); methotrexate (Otrexup, Rasuvo, Trexall); rituximab (Rituxan); steroids oo ay ku jiraan dexamethasone, methylprednisolone (A-Methapred, Medrol, Solu-Medrol), prednisolone (Orapred, Pediapred), iyo prednisone (Rayos); tocilizumab (Actemra) iyo tofacitinib (Xeljanz).

Dhakhtarkaaga ayaa kaa ilaalin doona calaamadaha cudurka inta lagu jiro iyo kadib daaweyntaada. Haddii aad isku aragto mid ka mid ah calaamadaha soo socda ka hor intaadan bilaabin daaweyntaada ama haddii aad isku aragto mid ka mid ah astaamahan soo socda inta lagu jiro ama waxyar ka dib daaweyntaada, isla markiiba wac dhakhtarkaaga: qandho; dhidid; qarqaryo; muruq xanuun; qufac; qufaca xabka dhiigga; neefta oo ku qabata; miisaanka oo yaraada; maqaar diiran, casaan ah, ama xanuun leh; nabarrada maqaarka; dareen soo noqnoqda, xanuun leh, ama gubasho ah inta lagu jiro kaadida; shuban; calool xanuun; ama daal fara badan.

Waxaa laga yaabaa inaad hore u qaadday cudurka qaaxada (TB; infekshan daran oo sambabaha ah) laakiin aadan lahayn wax calaamado ah oo cudurka ah. Xaaladdan oo kale, isticmaalka cirbada sarilumab waxay ka dhigi kartaa infekshinkaaga mid aad u daran oo kuu sababa inaad yeelato calaamado. Dhaqtarkaaga wuxuu sameyn doonaa baaritaanka maqaarka si loo arko inaad qabto infekshinka TB-da ee aan firfircooneyn kahor intaadan bilaabin daaweyntaada cirbadda sarilumab. Haddii loo baahdo, dhakhtarkaagu wuxuu ku siin doonaa daawo aad ku daaweyso infekshankan ka hor intaadan bilaabin isticmaalka cirbadda sarilumab. U sheeg dhakhtarkaaga haddii aad qabtid ama aad waligaa qaaxo qabtid, haddii aad ku nooleyd ama aad booqatay waddan ay qaaxadu ku badan tahay, ama haddii aad ag joogtay qof qaba tiibay. Haddii aad leedahay mid ka mid ah astaamaha soo socda ee TB, ama haddii aad isku aragto mid ka mid ah astaamahan inta lagu jiro daweyntaada, wac dhakhtarkaaga isla markiiba: qufac, qufac xabka dhiigga, miisaanka oo yaraada, murqaha oo yaraada, ama qandho.

Dhakhtarkaaga ama farmashiistahaaga ayaa ku siin doona warqada macluumaadka bukaanka soo saaraha (Hagaha Daawada) markaad bilowdo daaweynta cirbadda sarilumab iyo mar kasta oo aad dib u buuxiso dawadaada. Si taxaddar leh u akhri macluumaadka oo weydii dhakhtarkaaga ama farmashiistaha haddii aad wax su'aalo ah qabtid. Waxa kale oo aad booqan kartaa websaydhka Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ama websaydhka soosaaraha si aad u hesho Hagaha Daawada.

Cirbadda Sarilumab ayaa loo isticmaalaa keligeed ama daawooyin kale si loogu daaweeyo rheumatoid arthritis (RA: xaalad jirku ku weerarayo kala-goysyadiisa u gaarka ah taasoo keenta xanuun, barar, iyo shaqeyn la'aan). Sarilumab sida caadiga ah waxaa isticmaala dadka aan ku caawin dawooyinka kale qaarkood ee RA ama kuwa aan qaadan karin daawooyinkan. Cirbadda Sarilumab waxay ku jirtaa nooc daawooyin ah oo loo yaqaan 'interleukin-6 (IL-6) inhibitors'. Waxay ku shaqeysaa iyadoo la xannibayo waxqabadka interleukin-6, walax jirka ku jirta oo keenta caabuq.

Cirbadda Sarilumab waxay u timaaddaa sidii cirbad horay loo soo buuxiyay si loogu durayo subag hoosaadka (maqaarka hoostiisa). Badanaa waxaa la isticmaalaa 2dii toddobaadba mar.Dhakhtarkaaga ayaa laga yaabaa inuu go'aansado in adiga ama daryeelahaaga aad ku muddaan irbadaha guriga. Dhakhtarkaaga ayaa ku tusi doona adiga ama qofka lagu durayo daawada sida loo isku duro. Adiga ama qofka duraya daawada sidoo kale waa inaad aqrisaan tilmaamaha qoran ee isticmaalka ee la socda daawada. Hubso inaad weydiiso dhakhtarkaaga ama farmashiistaha haddii aad wax su'aalo ah ka qabtid sida loo duro daawada.

Ka saar daawada qaboojiyaha 30 daqiiqo ka hor intaadan u durin daawada. Ku talaabso dusha sare oo u oggolow inuu gaaro heerkulka qolka. Markaad ka saareyso saliingada la buuxiyay sanduuqa, taxaddar inaad ku haysato oo keliya bartamaha jirka saliingaha oo ha ruxin saliingaha ama ha ka saarin daboolka daboolaya cirbadda. Ha isku dayin inaad diiriso daawada adoo ku kululeynaya microwave, oo ku ridaya biyo diirran ama qorrax toos ah, ama qaab kale.

Kahor mudista, hubi saliingaha horay loo soo buuxiyay si aad u hubiso in taariikhda dhicitaanka ee lagu daabacay baakadka aysan dhaafin. Si dhow u fiiri dareeraha saliingaha ku jira. Dareeraha waa inuu noqdaa mid huruud ah ama midab jaalle ah waana inuusan noqon mid daruuro leh ama midab doorsoon leh ama ay ku jiraan buro ama qaybo. Hubi haddii saliingadu u muuqato mid dhaawacan ama haddii daboolka irbadda uu maqan yahay ama uusan ku xirnayn. Wac farmashiistahaaga haddii ay jiraan wax dhibaato ah hana ku durin daawada.

Waad ku duri kartaa cirbada bowdada horteeda ama meel kasta oo calooshaada ah marka laga reebo xudduntaada (badhanka caloosha) iyo aagga 2 inji oo ku wareegsan. Haddii qof kale ku durayo daawadaada, aagga kore ee gacmaha kore sidoo kale waa la isticmaali karaa. Ha ku durin daawada maqaarka jilicsan, nabar, nabar, ama nabar leh. Xulo meel kale markasta oo aad isku durto dawada.

Dib ha u isticmaalin siriinabyada sarilumab ee horay loo sii shubay hana dib ugu soo ceshanin saliingaha isticmaalka kadib. Ku tuur cirbadaha la isticmaalay weel u adkaysata daloolka oo weydii farmashiistahaaga sida loo tuuro weelka.

Dhakhtarkaaga ayaa si taxaddar leh kuu ilaalin doona si uu u arko sida wanaagsan ee ay u shaqeyso cirbadda sarilumab. Dhakhtarkaaga ayaa laga yaabaa inuu saxo qiyaastaada ama dib u dhigo ama joojiyo daaweyntaada iyadoo kuxiran jawaabtaada daawadan. Waa muhiim inaad u sheegto dhakhtarkaaga sida aad dareemeyso inta lagu jiro daaweyntaada.

Cirbadda Sarilumab ayaa laga yaabaa inay gacan ka geysato xakameynta calaamadahaaga, laakiin ma daaweyn doonto xaaladdaada. Sii wad inaad isticmaasho cirbadda sarilumab xitaa haddii aad caafimaad qabto. Ha u joojin isticmaalka cirbadda sarilumab adigoon la hadlin dhakhtarkaaga.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada duritaanka sarilumab,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay sarilumab, daawooyin kale, ama mid ka mid ah waxyaabaha ku jira irbadda sarilumab. Weydii farmashiistahaaga ama ka hubi Hagaha Daawada liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto dawooyinka ku taxan qaybta DIGNIIN MUHIIM AH iyo mid kasta oo ka mid ah kuwan soo socda: asbiriin iyo dawooyinka kale ee non-steroid anti-inflammatory (NSAIDs) sida ibuprofen (Advil, Motrin), iyo naproxen (Aleve, Anaprox, kuwo kale); atorvastatin (Lipitor, Caduet); clarithromycin (Biaxin, gudaha Prevpac); cyclosporine (Gengraf, Neoral, Sandimmune); erythromycin (EES, Eryc, PCE); lovastatin (Altoprev); p-pillerka (kaniiniyada xakameynta dhalmada); quinidine (oo ku taal Nuedexta); simvastatin (Zocor, oo ku yaal Vytorin); sirolimus (Rapamune, Torisel); tacrolimus (Astagraf, Envarsus XR, Prograf); telithromycin (Ketek); theophylline (Theo-24, Theochron); iyo warfarin (Coumadin, Jantoven). Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca. Daawooyin kale oo badan ayaa sidoo kale la falgeli kara cirbadda sarilumab, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan.
• u sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa ku dhacday diverticulitis (boorsooyin yaryar oo ku jira dahaadhka mindhicirka weyn oo barari kara), boogaha calooshaada ama mindhicirada, kansarka, ama cagaarshowga B ama cudur kale oo beerka ah. Sidoo kale u sheeg dhakhtarkaaga haddii aad qorsheyneyso inaad sameyso qalliin ama habraac caafimaad mustaqbalka dhow.
• u sheeg dhakhtarkaaga haddii aad dhawaan heshay ama laguu qorsheeyay inaad hesho wax tallaal ah. Waa inaadan helin wax talaal ah inta aad isticmaaleyso cirbadda sarilumab adigoon dhaqtarkaaga la hadlin.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanaysid duritaanka sarilumab, wac dhakhtarkaaga. Haddii aad qaadatay cirbadaha sarilumab intaad uurka lahayd, u sheeg dhakhtarkaaga ka hor inta ilmuhu aanu qaadan wax tallaal ah.
• haddii aad qalliin sameyneyso, oo ay ku jiraan qalliinka ilkaha, u sheeg dhakhtarka ama dhakhtarka ilkaha inaad qaadanayso irbadda sarilumab.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Weydii dhakhtarkaaga waxa la sameeyo haddii aad ilowdo inaad isku durto qadar. Ha u isticmaalin qaadasho laba jibbaar ah si aad u dhammaystirto mid kaa dhaafay

Cirbadda Sarilumab waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• sanka oo xirma ama duuf leh
• guduudasho ama cuncun meel u dhow meesha daawada lagu duray

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:

• dhiigbax ama nabar fudud
• finan
• finan
• dhib liqidda ama neefsashada
• bararka bushimahaaga, carrabkaaga, ama wejigaaga
• xabad xanuun
• dawakh ama suuxdin
• calool xanuun
• matagid
• xanuun, gubasho, kabuubyo, ama xoqid maqaarka ama finanka maqaarkaaga ah

Daawooyinka la midka ah cirbadaha sarilumab waxay sababi karaan halista sii kordheysa ee kansarka. Kala hadal dhakhtarkaaga khataraha isticmaalka daawadan.

Cirbadda Sarilumab waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad isticmaaleyso daawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hay kartoonka ay u soo gashay si looga ilaaliyo iftiinka, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi qaboojiyaha laakiin ha barafoobin. Haddii daawada lagu keydiyay qaboojiyaha, waa in lagu isticmaalo 14 maalmood gudahood.

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa tijaabooyinka shaybaarka qaarkood si loo hubiyo jawaabta jirkaaga ee duritaanka sarilumab.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

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