Qoraa: Janice Evans
Taariikhda Abuurista: 28 Julay 2021
Taariikhda Cusboonaysiinta: 18 Noofeembar 2024
Anonim
Romosozumab in osteoporosis – Video Abstract [127568]
Dareemoleyad: Romosozumab in osteoporosis – Video Abstract [127568]

Qanacsan

Cirbada Romosozumab-aqqg waxay sababi kartaa dhibaatooyin wadnaha oo halis ah ama halis galiya sida wadno qabad ama istaroog. U sheeg dhakhtarkaaga haddii aad isku aragto ama aad waligaa wadno istaag ama istaroog kugu dhacdo, gaar ahaan haddii ay dhacday sanadkii la soo dhaafay. Haddii aad isku aragto mid ka mid ah astaamahan soo socda inta lagu jiro daweyntaada, isla markiiba wac dhakhtarkaaga: laabta xanuun ama cadaadis, neef qabad, madax-xanuun dareemo, wareer, madax-xanuun, kabuubyo ama daciifnimo xagga wejiga ah, gacanta, ama lugaha, hadalka oo adkaada, arag isbeddellada, ama luminta dheelitirka.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa baaritaano gaar ah si loo hubiyo jawaabta jirkaaga ee duritaanka romosozumab-aqqg.

Dhakhtarkaaga ama farmashiistahaaga ayaa ku siin doona warqada macluumaadka bukaanka soo saaraha (Hagaha Daawada) markaad bilawdo daaweynta cirbadeynta romosozumab-aqqg iyo markasta oo aad dib u buuxiso dawadaada. Si taxaddar leh u akhri macluumaadka oo weydii dhakhtarkaaga ama farmashiistaha haddii aad wax su'aalo ah qabtid. Waxa kale oo aad booqan kartaa websaydhka Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ama websaydhka soosaaraha si aad u hesho Hagaha Daawada.


Cirbadeynta Romosozumab-aqqg waxaa loo isticmaalaa in lagu daaweeyo lafo-beelka lafa-beelka (xaalad ah in lafuhu noqdaan kuwo khafiif ah oo daciif ah oo si fudud u jaba) haweenka postmenopausal (haweenka la kulmay isbeddel nololeed; dhammaadka xilliyada caadada) kuwaas oo halista sare ee jabka ama marka daaweynta kale ee lafa-beelka lafta ay wax ka tari weyday ama aan loo dulqaadan karin. Cirbadeynta Romosozumab-aqqg waxay ku jirtaa nooc daawooyin ah oo loo yaqaan monoclonal antibodies. Waxay ku shaqeysaa kordhinta sameynta lafaha iyo yareynta burburka lafaha.

Cirbadeynta Romosozumab-aqqg waxay u timaadaa xalka si subag ahaan (maqaarka hoostiisa) loogu duraa aagga calooshaada, gacanta kore, ama bowdada. Waxaa badanaa lagu duraa bixiye daryeel caafimaad bishii 12 jeer.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan helin duritaanka romosozumab-aqqg,

  • u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay romosozumab-aqqg, dawooyin kale, ama mid ka mid ah waxyaabaha ku jira irbadda romosozumab-aqqg. Weydii farmashiistahaaga ama ka hubi Hagaha Daawada liiska waxyaabaha ay ka kooban yihiin.
  • u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: angiogenesis inhibitors sida axitinib (Inlyta), bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), ama sunitinib (Sutent); bisphosphonates sida alendronate (Binosto, Fosamax), etidronate, ama ibandronate (Boniva); daawooyinka kiimikada ee kansarka; denosumab (Prolia); ama daawo steroid ah sida dexamethasone, methylprednisolone (Medrol), iyo prednisone (Rayos). Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
  • u sheeg dhakhtarkaaga haddii aad leedahay heerar hoose oo kaalshiyam ah. Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaadan qaadan cirbadeynta romosozumab-aqqg.
  • u sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa qabto cudur kalyaha ah ama lagu daweynayo hemodialysis (daaweyn looga saarayo wasakhda dhiigga markay kelyahu shaqeynayaan).
  • u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Cirbadeynta Romosozumab-aqqg waxaa kaliya loo oggol yahay daaweynta haweenka dhalmada kadib. Haddii aad uur yeelato inta aad qaadanayso cirbadeynta romosozumab-aqqg, isla markiiba wac dhakhtarkaaga.
  • waa inaad ogaataa in cirbadeynta romosozumab-aqqg ay sababi karto osteonecrosis ee daanka (ONJ, xaalad daran oo lafta daanka ah), gaar ahaan haddii aad u baahan tahay qalliin ilkaha ah ama daaweyn inta aad daawada isticmaaleysid. Dhakhtarka ilkaha waa inuu baaraa ilkahaaga oo uu sameeyaa wixii daaweyn ah ee loo baahan yahay, oo ay ku jiraan nadiifinta, ka hor intaadan bilaabin inaad isticmaasho cirbadeynta romosozumab-aqqg Hubso inaad cadayato oo aad si sax ah u nadiifiso afkaaga inta aad isticmaaleyso cirbadeynta romosozumab-aqqg. La hadal dhakhtarkaaga kahor intaadan helin daaweyn ilko inta aad isticmaaleysid dawadan.

Intaad qaadaneysid cirbadeynta romosozumab-aqqg, waxaa muhiim ah inaad hesho kalsiyum iyo fitamiin D. Takhtarkaaga ayaa kuu qori kara waxyaabo dheeri ah haddii qaadashada cuntadaadu kugu filneyn.


Haddii aad seegto ballan si aad u hesho qaddar, samee ballan kale sida ugu dhakhsaha badan ee suurtogalka ah. Qiyaastaada xigta ee cirbada romosozumab-aqqg waa in la jadwaleeyaa hal bil laga bilaabo taariikhda duritaanka ugu dambeeya.

Cirbada Romosozumab-aqqg waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

  • kalagoys xanuun
  • xanuun iyo guduudasho goobta duritaanka

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:

  • barar wejiga, dibnaha, afka, carrabka, ama cunaha
  • dhib liqidda ama neefsashada
  • finan
  • guduudasho, miisaan, ama finan
  • bowdo cusub ama aan caadi ahayn, sinta, ama gumaarka
  • murqaha murqaha, kala-baxa, ama casiraad
  • kabuubyo ama xoqid faraha, suulasha, ama afka

Cirbada Romosozumab-aqqg waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn inta aad qaadanaysid dawadan.


Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto cirbadeynta romosozumab-aqqg.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

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