Rifampin

Qanacsan

• Kahor qaadashada rifampin,
• Rifampin wuxuu sababi karaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba wac dhakhtarkaaga:
• Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

Rifampin waxaa loo isticmaalaa daawooyin kale si loogu daweeyo cudurka qaaxada (TB; infekshan daran oo saameeya sambabaha iyo mararka qaarkood qaybaha kale ee jirka). Rifampin sidoo kale waxaa loo isticmaalaa in lagu daaweeyo dadka qaarkood ee qaba Neisseria meningitidis (nooc bakteeriya ah oo sababi kara infekshan daran oo loo yaqaan meningitis) infekshannada sanka ama cunaha. Dadkani ma aysan soo saarin astaamaha cudurka, waxaana daaweyntaan loo adeegsadaa in looga hortago inay ku dhacaan dadka kale. Rifampin looma isticmaali karo in lagu daaweeyo dadka ku dhacay astaamaha qoorgooyaha. Rifampin wuxuu ku jiraa nooc daawo ah oo loo yaqaan antimycobacterials. Waxay ku shaqeysaa iyada oo la dilayo bakteeriyada keenta infekshinka.

Antibiyootikada sida rifampin uma shaqeyn doono hargabka, ifilada, ama infekshannada kale ee fayraska keena. Isticmaalka antibiyootikada markii aan loo baahnayn waxay kordhisaa halista aad u qaadi karto jeermis dambe oo iska caabiya daaweynta antibiyootikada.

Rifampin wuxuu u yimaadaa sida kaabsol uu afka ku qaato. Waa in lagu qaataa galaas buuxa oo biyo ah calool madhan, 1 saac ka hor ama 2 saacadood cuntada ka dib. Marka rifampin loo isticmaalo daaweynta qaaxada, waxaa la qaataa hal mar maalintii. Marka loo isticmaalo rifampin si looga hortago faafitaanka Neisseria meningitidis bakteeriyada dadka kale, waxaa la qaataa laba jeer maalintii 2 maalmood ama hal mar 4 maalmood. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. U qaado rifampin sida saxda ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

U sheeg dhakhtarkaaga ama farmashiistaha haddii aadan liqi karin kaabsoosha. Farmasiilahaaga ayaa kuu diyaarin kara dareere ah inaad qaadato halkii.

Haddii aad u qaadaneysid dawada qaaxada qaaxada, dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaad qaadato rifampin dhowr bilood ama ka badan. Sii wad inaad qaadato dawada loo yaqaan 'rifampin' ilaa aad ka dhammeysid rijeetada laguu qoray xitaa haddii aad fiicnaan dareento, kana taxaddar inaadan dhaafin qiyaasaha. Haddii aad dhakhso u joojiso qaadashada rifampin, infekshankaaga gebi ahaanba lama daaweyn karo bakteeriyaduna waxay noqon kartaa mid iska caabbisa antibiyootikada. Haddii aad seegto qiyaasta loo yaqaan 'rifampin', waxaa laga yaabaa inaad yeelato calaamado aan raaxo lahayn ama halis ah markii aad bilowdo inaad daawada mar labaad qaadato.

Rifampin sidoo kale mararka qaar waxaa loo isticmaalaa in lagu daaweeyo infekshannada ay sababaan noocyada kale ee bakteeriyada ah iyo in looga hortago infekshinka dadka ku dhow dhow qofka qaba infekshannada bakteeriyada qaarkood ee halista ah. Kala hadal dhakhtarkaaga khataraha aad u leedahay isticmaalka dawadan xaaladaada.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada rifampin,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay rifampin, rifabutin (Mycobutin), rifapentine (Priftin), daawooyin kale, ama mid ka mid ah maaddooyinka ku jira kaabsoolka rifampin Weydii dhakhtarkaaga ama farmashiistaha liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga haddii aad qaadanayso mid ka mid ah daawooyinka soo socda: atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), praziquantel (Biltricide), saquinavir (Invirase), tipranavir (Aptivus), or ritonavir (Norvir) and saquina (Invirase) waa la wada qaaday. Dhakhtarkaaga ayaa u badan inuu kuu sheego inaadan qaadan dawada loo yaqaan 'rifampin' haddii aad qaadanaysid mid ka mid ah daawooyinkan. Haddii aad qaadanayso qoriga loo yaqaan 'rifampin' oo aad u baahan tahay inaad qaadato praziquantal (Biltricide), waa inaad sugtaa ugu yaraan 4 toddobaad ka dib markaad joojiso qaadashada rifampin ka hor intaadan bilaabin qaadashada praziquantel.
• u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: daawooyinka xinjirowga lidka ku ah ('khafiifiyeyaasha dhiigga') sida warfarin (Coumadin, Jantoven); antifungals sida fluconazole (Diflucan), itraconazole (Onmel, Sporanox), iyo ketoconazole; atovaquone (Mepron, Malarone); barbiturates sida phenobarbital; beta beta blockers sida atenolol (Tenormin), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), iyo propranolol (Inderal, Innopran); Kaalshiyamka kaaliyayaasha sida diltiazem (Cardizem, Cartia, Tiazac), nifedipine (Adalat, Procardia), iyo verapamil (Calan, Verelan); chloramphenicol; clarithromycin (Biaxin); cyclosporine (Gengraf, Neoral, Sandimmune); daclatasvir (Daklinza); dapsone; diazepam (Valium); doxycycline (Monodox, Oracea, Vibramycin); efavirenz (Sustiva); enalapril (Vaseretic); antibiyootigyada fluoroquinolone sida ciprofloxacin (Cipro) iyo moxifloxacin (Avelox); gemfibrozil (Lopid); haloperidol (Haldol); ka hortagga uurka ee hormoonka (kaniiniyada ka hortagga uurka, dhejisyo, giraan, ama irbado); daaweynta beddelka hormoonka (HRT); indinavir (Crixivan); irinotecan (Camptosar); isoniazid (gudaha Rifater, Rifamate); levothyroxine (Levoxyl, Synthroid, Tirosint); losartan (Cozaar); daawooyinka loogu talagalay garaaca wadnaha aan caadiga ahayn sida digoxin (Lanoxin), sibibramram (Norpace), mexiletine, propafenone (Rythmol), iyo quinidine (Nuedexta); dawooyinka qalalaasaha sida phenytoin (Dilantin, Phenytek); methadone (Dolophine, Methadose); daawooyinka daroogada ee xanuunka sida oxycodone (Oxaydo, Xtampza) iyo morphine (Kadian); ondansetron (Zofran, Zuplenz); daawooyinka afka laga qaato ee sonkorowga sida glipizide (Glucotrol), glyburide (Diabeta), iyo rosiglitazone (Avandia); probenecid (Probalan); quinine (Qualquin); simvastatin (Flolipid, Zocor), steroids sida dexamethasone (Decadron), methylprednisolone (Medrol), iyo prednisone; sofosbuvir (Sovaldi); tamoxifen (Soltamox); toremifene (Fareston); trimethoprim iyo sulfamethoxazole (Bactrim, Septra); tacrolimus (Prograf); theophylline (Elixophyllin, Theo-24); tricyclic antidepressants sida amitriptyline iyo nortriptyline (Pamelor); zidovudine (Retrovir, ee Trizivir), iyo zolpidem (Ambien). Daawooyin kale oo badan ayaa laga yaabaa inay la falgalaan rifampin, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
• haddii aad qaadanayso dawada antacids, qaado rifampin ugu yaraan 1 saac ka hor intaadan qaadan antacids-ka.
• u sheeg dhakhtarkaaga haddii aad qaadanaysid ama aad isticmaaleysid ka hortagga uurka ee hormoonnada (kaniiniyada ka hortagga uurka, dhejisyo, faraantiyo, maqaar-gelin, iyo irbado). Rifampin wuxuu yareyn karaa waxtarka uur-qaadidda ee hormoonnada. Waa inaad isticmaashaa hab kale oo xakameynta dhalmada ah inta aad qaadaneysid dawadan. Kala hadal dhakhtarkaaga waxyaabaha ku saabsan xakameynta uurka inta aad qaadaneysid dawada loo yaqaan 'rifampin'.
• u sheeg dhakhtarkaaga haddii aad qabtid ama waligaa aad qabtid sonkorow, porphyria (xaalad ay walxaha dabiiciga ah qaarkood ku soo baxaan jirka oo sababi kara calool xanuun, isbeddel ku yimaada fikirka iyo dabeecadda, ama astaamo kale), xaalad kasta oo saameysa qanjirkaaga adrenal ( qanjir yar oo ku xiga kilyaha oo soo saaraya walxo dabiici ah oo muhiim ah) ama cudurka beerka.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelatid inta aad qaadanaysid rifampin, wac dhakhtarkaaga.
• u sheeg dhakhtarkaaga haddii aad xidhato muraayadaha indhaha oo jilicsan. Rifampin wuxuu sababi karaa astaamaha casaanka ee joogtada ah muraayadaha indhahaaga haddii aad xidhato inta lagaa dawaynayo rifampin.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Ha seegin qiyaasta qoriga loo yaqaan 'rifampin'. Qiyaasaha la la'yahay ayaa kordhin kara halista ah inaad la kulanto waxyeelo daran. Haddii aad seegto qaddar, qaado qiyaasta la seegay isla marka aad xusuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaasta xigta, ka bood qiyaasta la seegay oo wac dhakhtarkaaga. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Rifampin wuxuu sababi karaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• midab ku meel gaar ah (huruud, casaan guduudan, ama midab bunni ah) maqaarkaaga, ilkaha, candhuufta, kaadida, saxarada, dhididka, iyo ilmada)
• cuncun
• dhaqid
• madax xanuun
• lulmid
• dawakhaad
• isuduwid la'aan
• adkaanshaha feejignaanta
• jahwareer
• isbeddelada dhaqanka
• daciifnimada muruqyada
• kabuubyo
• xanuun ku dhaca gacmaha, gacmaha, cagaha, ama lugaha
• laabjeex
• calool xanuun
• cunto xumo
• lallabbo
• matagid
• shuban
• gaaska
• caadooyin xanuun leh ama aan caadi ahayn
• aragtida isbeddelay

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba wac dhakhtarkaaga:

• saxaro biyo ah ama dhiig leh, calool xanuun, ama qandho inta lagu jiro daweynta ama ilaa laba ama in ka badan bilood kadib joojinta daaweynta
• finan; finan; qandho; qarqaryo; bararka indhaha, wejiga, dibnaha, carrabka, ama cunaha; dhib liqidda ama neefsashada; neefta oo ku qabata; xiiq; qanjidhada qanjidhada oo barara; cune xanuun; isha casaanka ah; astaamaha hargabka oo kale; dhiigbax ama nabar aan caadi ahayn; ama barar wadajir ah ama xanuun
• lallabbo, matag, rabitaanka cuntada oo kaa yaraada, kaadida oo yaraata, ama maqaarka ama indhaha oo hurdi noqda

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Rifampin wuxuu sababi karaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi heerkulka qolka oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha).

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

• lallabbo
• matagid
• calool xanuun
• cuncun
• madax xanuun
• miyir beelid
• hurdi maqaarka ama indhaha
• midab casaan ah oo maqaarka ah, candhuufta, kaadida, saxarada, dhididka, iyo ilmada
• danqasho qaybta kore ee midig ee caloosha
• bararka indhaha ama wajiga
• garaaca wadnaha oo dhakhso ah ama aan caadi ahayn
• qalal

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa tijaabooyinka shaybaarka qaarkood si loo hubiyo jawaabtaada 'rifampin'.

Kahor baaritaanka shaybaarka, oo ay kujirto baaritaanka daroogada, usheeg shaqaalaha sheybaarka inaad qaadanayso rifampin. Rifampin wuxuu sababi karaa natiijooyinka tijaabooyinka baaritaanka dawooyinka qaarkood inay noqdaan kuwa wanaagsan inkasta oo aadan qaadan daawooyinka.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Rifadin^®
• Rimactane^®

• Rifamate^® (oo ay ku jiraan Isoniazid, Rifampin)
• Rifater^® (oo ay kujiraan Isoniazid, Pyrazinamide, Rifampin)