Itraconazole

Qanacsan

• Kahor qaadashada itraconazole,
• Itraconazole waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac dhakhtarkaaga isla markiiba:
• Haddii aad isku aragto mid ka mid ah astaamaha soo socda ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, jooji qaadashada itraconazole isla markaana wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:

Itraconazole wuxuu sababi karaa wadne istaag (xaalad wadnaha uusan ku soo shubi karin dhiig ku filan jirka). U sheeg dhakhtarkaaga haddii aad qabtid ama aad waligaa wadnaha istaagtay. Dhakhtarkaagu wuxuu kuu sheegi karaa inaadan qaadan itraconazole. Sidoo kale u sheeg dhakhtarkaaga haddii aad qabtid ama aad waligaa wadno-istaag kugu dhacday; garaaca wadnaha oo aan joogto ahayn; ama nooc kasta oo kale oo ah wadnaha, sambabka, beerka ama cudurka kalyaha. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, jooji qaadashada itraconazole isla markaana wac dhakhtarkaaga isla markiiba: neefta oo ku qabata; qufaca xaako cad ama casaan; daciifnimo; daal fara badan; garaaca wadnaha oo dhakhso ah; bararka cagaha, anqawyada, ama lugaha; soo jeedka habeenkii; iyo miisaanka oo kordha.

Ha qaadan cisapride (Propulsid) (oo aan laga heli karin Mareykanka), sibibramram (Norpace), dofetilide (Tikosyn), dronedarone (Multaq), eplerenone (Inspra), daawooyinka nooca ergot sida dihydroergotamine (DHE, Migranal), ergotamine ( Ergomar, Cafergot, Migergot), methylergometrine (Methergine); felodipine (Plendil), irinotecan (Camptosar), ivabradine (Corlanor), levomethadyl acetate (Orlaam) (oo aan laga heli karin Mareykanka), lovastatin (Altoprev, Advicor), lurasidone (Latuda), methadone (Dolophine, Methadose), midazolam ( afka laga qaado), nisoldipine (Sular), pimozide (Orap), quinidine (in Nuedexta), ranolazine (Ranexa), simvastatin (Zocor, in Simcor, in Vytorin), ticagrelor (Brilinta), and triazolam (Halcion) while itraconazole iyo 2 usbuuc kadib. U sheeg dhakhtarkaaga haddii aad qabto cudur kelyaha ama beerka ah oo aad qaadatid mid ka mid ah daawooyinka soo socda: colchicine (Colcrys, Mitigare), fesoterodine (Toviaz), solifenacin (Vesicare), ama telithromycin (Ketek). Ku qaadashada daawooyinkaas daawada 'itraconazole' waxay sababi kartaa dhibaatooyin wadne oo daran oo ay ka mid tahay QT dheereynta (wadna garaac aan caadi ahayn oo u horseedi kara suuxdin, miyir beelid, suuxdin, ama dhimasho lama filaan ah).

Kala hadal dhakhtarkaaga khataraha qaadashada itraconazole.

Kaabsulka 'Itraconazole' waxaa loo isticmaalaa in lagu daaweeyo infekshannada fungal ee sambabaha oo ku faafi kara jirka oo dhan. Kaabsulka 'Itraconazole' sidoo kale waxaa loo isticmaalaa in lagu daaweeyo infekshannada fungal ee ciddiyaha. Kiniiniyada 'Itraconazole' iyo kaabsoosha ayaa loo isticmaalaa in lagu daaweeyo infekshannada fungal ee caguhu ku dhacaan. Xalka afka (Itraconazole) (dareeraha) ayaa loo isticmaalaa in lagu daaweeyo infekshanka afka iyo cunaha ama hunguriga (tubada isku xirta cunaha iyo caloosha). Itraconazole waxay ku jirtaa fasal ka mid ah antifungals loo yaqaan 'triazoles'. Waxay ku shaqeysaa iyada oo hoos u dhigeysa koritaanka fangaska ee sababa infekshinka.

Itraconazole waxay u timaaddaa kaabsul, kiniin, iyo xalka (dareeraha) afka lagu qaato. Haddii aad u qaadaneysid daawada loo yaqaan 'itraconazole' si aad ugu daaweyso infekshannada fungal ee sambabka, kaabsoosha waxaa badanaa la qaataa inta lagu jiro ama isla marka la cuno cunno buuxda hal ama laba jeer maalintii ugu yaraan 3 bilood. Si kastaba ha noqotee, haddii aad u qaadaneysid dawada loo yaqaan 'itraconazole' si loo daweeyo infekshan fangas oo halis ah oo ku dhaca sambabada, kaabsulka waxaa lagu qaadan karaa cunto saddex jeer maalintii 3-da maalmood ee ugu horreeya daaweynta ka dibna la qaataa hal mar ama laba jeer maalintii iyadoo ugu yaraan la cunayo 3 bilood. Haddii aad u qaadaneysid daawada loo yaqaan 'itraconazole' si aad u daaweyso infekshannada fungal ee cagaha cidiyaha (oo ay ku jiraan ama aan lahayn infakshanka ciddiyaha), kaabsulka ama kiniiniyada waxaa caadi ahaan la qaataa maalintii hal mar iyadoo la cunayo cunto dhan 12 toddobaad. Haddii aad u qaadaneysid dawada loo yaqaan 'itraconazole' si aad u daaweyso infekshannada fungal oo keliya ciddiyaha, kaabsulka badanaa waxaa la qaataa laba jeer maalintii oo leh cunto buuxa muddo 1 toddobaad ah, waa laga booday muddo 3 toddobaad ah, ka dibna waxaa la qaataa laba jeer maalintii iyadoo la cunayo isbuuc. Xalka afka ee loo yaqaan 'Itraconazole' waxaa badanaa lagu qaadaa calool madhan hal jeer ama laba jeer maalintii ilaa 1 ilaa 4 toddobaad ama mararka qaarkood ka sii dheer. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado itraconazole sida saxda ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

Liq kaabsoosha 'itraconazole' oo dhan; ha furin, calalin, ama burburin.

Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaad ku qaadatid kaabsulka 'itraconazole' oo leh cabitaanka kookaha oo jilicsan haddii aad leedahay xaalado caafimaad oo gaar ah ama aad qaadanayso mid ka mid ah daawooyinka soo socda: cimetidine; famotidine (Pepcid); nizatidine (Axid); proton-pump inhibitors sida esomeprazole (Nexium, in Vimovo), lansoprazole (Prevacid, in Prevpac), omeprazole (Prilosec, in Zegerid), pantoprazole (Protonix), rabeprazole (AcipHex), ama ranitidine (Zantac). Raac tilmaamahan si taxaddar leh.

Si aad u qaadatid xalka afka ah ee loo yaqaan 'itraconazole' ee caabuqyada fungal ee ku dhaca afka ama cunaha, ku beddel 10 mililitir (qiyaastii 2 qaado) oo ah xalka afkaaga dhowr ilbiriqsiyo oo liq. Ku celi haddii ay lagama maarmaan noqoto in aad qaadatid qiyaastaada oo dhan.

Kaabsoosha 'Itraconazole' iyo xalka afka ayaa loo nuugaa jirka siyaabo kala duwan waxayna u shaqeeyaan sidii loo daaweyn lahaa xaalado kala duwan. Kaabsallada ha ku beddelin dareeraha ama dareeraha kaabsoolka. Hubso in farmashiistahaagu ku siiyo sheyga itraconazole ee dhakhtarkaagu kuu qoray.

Haddii aad u qaadaneysid dawada 'itraconazole' in lagu daaweeyo infekshanka ciddiyaha, ciddiyahaaga ayaa laga yaabaa in aysan u muuqan kuwo caafimaad qaba illaa ay cidiyaha cusub ka soo baxaan. Waxay qaadan kartaa ilaa 6 bilood in lagu beero ciddiyi ciddiyaha cusub ah iyo ilaa 12 bilood si loo beero suulasha cusub, marka waa inaadan filan inaad aragto horumar inta lagu jiro daaweyntaada ama dhowr bilood kadib. Sii wad qaadashada daawada 'itraconazole' xitaa haddii aadan arkin wax horumar ah.

Sii wad inaad qaadato daawada loo yaqaan 'itraconazole' ilaa dhakhtarkaagu kuu sheego inaad joojiso xitaa haddii aad caafimaad qabtid. Ha u joojin qaadashada daawada 'itraconazole' adiga oo aan la hadlin dhakhtarkaaga. Haddii aad si dhakhso leh u joojiso qaadashada daawada 'itraconazole', infekshankaaga ayaa laga yaabaa inuu soo noqdo muddo gaaban ka dib.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Itraconazole sidoo kale mararka qaarkood waxaa loo isticmaalaa in lagu daaweeyo noocyada kale ee infekshannada fungal iyo in laga hortago infekshannada fungal ee dadka qaba fayraska difaaca jirka ee aadanaha (HIV) ama ay yeeshaan cilladda difaaca jirka (AIDS). Kala hadal dhakhtarkaaga khataraha suurtagalka ah ee isticmaalka daroogada ee xaaladdaada.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada itraconazole,

• u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad xasaasiyad ku leedahay itraconazole; dawooyinka kale ee antifungal sida fluconazole (Diflucan), ketoconazole (Nizoral), ama voriconazole (Vfend); daawooyin kale, ama mid ka mid ah waxyaabaha ku jira alaabada itraconazole. Haddii aad qaadanaysid xalka afka loo qaato ee itraconazole, u sheeg dhakhtarkaaga haddii aad xasaasiyad ku leedahay daawooyinka saccharin ama sulfa. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad qaadanaysid dawooyinka soo socda ama aad qaadatay 2-dii toddobaad ee ugu dambeeyay ka hor intaadan bilaabin daaweynta itraconazole: carbamazepine (Epitol, Tegretol, Teril, kuwa kale); efavirenz (Sustiva, oo ku taal Atripla); isoniazid (Laniazid, Rifamate, Rifater); rifabutin (Mycobutin); rifampicin; nevirapine (Viramune); phenobarbital; iyo phenytoin (Dilantin, Phenytek).
• u sheeg dhakhtarkaaga ama farmashiistaha haddii aad qaadanaysid daawooyinka soo socda: aliskiren (Tekturna, in Amturnide, Tekamlo, and Tekturna HCT), apixaban (Eliquis), axitinib (Inlyta), colchicine (Colcrys, Mitigare), dabrafemob (Taflinar), darifenacin , ), sunitinib (Sutent), tamsulosin (Flomax, in Jalyn), temsirolimus (Torisel), trabectedin (Yondelis), iyo vardenafil (Staxyn, Levitra). Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaadan qaadan daawooyinkan inta lagu jiro daaweyntaada iyo 2 toddobaad ka dib daaweyntaada itraconazole.
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada iyo alaabta dhirta ee aad qaadaneyso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto dawooyinka ku taxan qaybta DIGNIIN MUHIIM AH iyo mid ka mid ah kuwan soo socda: daawooyinka antibiyootikada sida ciprofloxacin (Cipro), clarithromycin (Biaxin, in PrevPac), erythromycin (EES Ery-Tab, kuwa kale), iyo telithromycin (Ketek) ; daawada xinjirowga lidka ku ah ('dhiig khafiifiyaha' ') sida warfarin (Coumadin, Jantoven); alprazolam (Xanax); danaysane (Emend); aripiprazole (Abilify); atorvastatin (Liifle, gudaha Caduet, Liptruzet); bortezomib (Velcade); bosentan (Tracleer); budesonide (Entocort EC, Pulmicort, Uceris); buprenorphine (Buprenex, Butrans, in Bunavail; kuwa kale); buspirone; ciclesonide (Alvesco, Omnaris, Zetonna); cilostazol (Pletal); cinacalcet (Sensipar); cyclosporine (Gengraf, Neoral, Sandimmune); dabigatran (Pradaxa); dexamethasone; diazepam (Valium); digoxin (Lanoxin); docetaxel (Docefrez, Taxotere); eletriptan (Relpax); erlotinib (Tarceva); fentanyl (Actiq, Duragesic, Fentora, Subsys, kuwa kale); fesoterodine (Toviaz); fluticasone (Flovent, Advair); gefitinib (Iressa); haloperidol (Haldol); Kahortagayaasha 'protease inhibitors' oo ay ka mid yihiin indinavir (Crixivan), darunavir (Prezista) oo lagu qaaday ritonavir, fosamprenavir (Lexiva) oo lagu qaaday ritonavir, iyo saquinavir (Invirase); imatinib (Gleevac); ixabepilone (Qalabka Ixempra); lapatinib (Tykerb); maraviroc (Selzentry); meloxicam (Mobic); methylprednisolone (Medrol); nadolol (Corgard, gudaha Corzide); oxybutynin (Ditropan XL, Oxytrol); oxycodone (Oxaydo, Oxycontin, Percodan; kuwa kale); ponatinib (Iclusig); praziquantel (Biltricide); quetiapine (Seroquel); ramelteon (Rozerem); repaglinide (Prandin, gudaha Prandimet); riociguat (Adempas); risperidone (Risperdal); saxagliptin (Kombiglyze XR, Onglyza); sirolimus (Rapamune); solifenacin (Vesicare); tacrolimus (Astagraf, Prograf); tadalafil (Adcirca, Cialis); tolterodine (Detrol); vardenafil (Levitra, Staxyn); verapamil (Calan, Covera, Verelan PM, in Tarka), vinblastine, vincristine (Marqibo Kit), iyo vinorelbine (Navelbine). Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca. Daawooyin kale oo badan ayaa sidoo kale la macaamili kara itraconazole, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liisaskan.
• haddii aad qaadanayso antacid, qaado 1 saac ka hor ama 2 saacadood ka dib qaadashada daawada 'itraconazole'.
• u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa soo martay xaaladaha lagu xusay qaybta DIGNIINTA MUHIIMKA ah, 'cystic fibrosis' (cudur ku dhasha oo sababa dhibaatooyin xagga neefsashada, dheefshiidka, iyo taranka ah), xaalad kasta oo hoos u dhigaysa xaddiga aashitada ee calooshaada, ama HIV.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Waa inaadan u qaadan itraconazole si loogu daaweeyo fungus fungus haddii aad uur leedahay ama aad uur qaadi karto. Waxaad bilaabi kartaa inaad qaadato itraconazole si loogu daaweeyo fungus fungus kaliya maalinta labaad ama seddexaad ee caadadaada markii aad hubto inaadan uur lahayn. Waa inaad isticmaashaa xakameynta dhalmada oo waxtar leh inta lagu jiro daaweyntaada iyo 2 bilood kadib. Haddii aad uur yeelato intaad qaadanayso daawada 'itraconazole' si aad u daweyso xaalad kasta, wac takhtarkaaga.
• waa inaad ogaataa in itraconazole laga yaabo inay kaa dawakho ama kuu keento aragti wareersan ama labalabeysa. Gaari ha wadin ama ha ku shaqeynin mishiin ilaa aad ka ogaato sida daawadani kuu saameyneyso.

Kala hadal dhakhtarkaaga wax ku saabsan cabitaanka casiirka canabka ah inta aad qaadanaysid dawadan.

Qaado qiyaasta la seegay isla marka aad xasuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaasta xigta, ka bood qiyaasta la seegay oo sii wad jadwalka daawadaada caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Itraconazole waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• shuban
• calool istaag
• gaas ama dibiro
• laabjeex
• dhadhan aan fiicnayn
• cirrid xanuun ama dhiig bax
• madax xanuun
• dawakhaad
• dhidid
• murqo xanuun ama daciifnimo
• kalagoys xanuun
• rabitaanka galmada ama awoodda
• gariirid
• niyad jab
• sanka oo dareera iyo calaamado kale oo qabow
• qandho
• timo lumis

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac dhakhtarkaaga isla markiiba:

• aragga daciifka ah ama aragtida laba-laabma
• dhagaha ka yeeraya
• Awood la'aanta xakameynta kaadida ama kaadida sidii caadiga ahayd

Haddii aad isku aragto mid ka mid ah astaamaha soo socda ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, jooji qaadashada itraconazole isla markaana wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:

• daal fara badan
• cunto xumo
• lallabbo
• calool xanuun
• matagid
• hurdi maqaarka ama indhaha
• kaadi madow
• saxaro cirro leh
• dareemid kabuubyo, xoqid, gariirid, gubasho, ama ku gurguurto maqaarka
• maqal la'aanta
• dareenka xasaasiga ah ee iftiinka
• cilad daran oo maqaarka ah
• maqal la'aanta
• finan
• finan
• cuncun
• barar wejiga, cunaha, carrabka, bushimaha, indhaha, gacmaha, anqawyada, ama lugaha hoose
• xabeeb
• neefsashada ama wax liqidda oo ku adkaata

Mid ka mid ah maaddooyinka ku jira xalka afka ee itraconazole ayaa sababay kansarka noocyada qaar ka mid ah xoolaha shaybaarka. Lama oga in dadka qaata xalka itraconazole ay leeyihiin halista sii kordheysa ee kansarka. Takhtarkaaga kala hadal halista qaadashada xalka itraconazole.

Itraconazole waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi heerkulka qolka oo ka fog kuleylka, iftiinka, iyo qoyaanka badan (ha ku jirin musqusha).

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa tijaabooyinka shaybaarka qaarkood si loo hubiyo jawaabtaada itraconazole.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray. Haddii aad wali leedahay astaamaha infekshinka markaad dhameysid itraconazole, wac dhakhtarkaaga.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

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