Glyburide iyo Metformin

Qanacsan

• Kahor qaadashada glyburide iyo metformin,
• Dawadani waxay sababi kartaa isbeddel ku dhaca sonkorta dhiiggaaga. Waa inaad ogaataa astaamaha sonkorta dhiiga oo hooseysa iyo kuwa sare iyo waxa la sameeyo haddii aad leedahay astaamahan.
• Glyburide iyo metformin waxay sababi karaan waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Haddii aad isku aragto mid ka mid ah astaamaha soo socda ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, isla markiiba wac dhakhtarkaaga:
• Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara astaamaha hypoglycemia iyo sidoo kale kuwa soo socda:

Metformin marar dhif ah ayay u keeni kartaa xaalad halis ah, oo nafta halis gelisa oo loo yaqaan 'lactic acidosis'. U sheeg dhakhtarkaaga haddii aad qabto cudur kelyaha ah. Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaadan qaadan glyburide iyo metformin. Sidoo kale, u sheeg dhakhtarkaaga haddii aad ka weyn tahay 65 sano iyo haddii aad waligaa isku aragtay wadne qabad; istaroog; ketoacidosis-ka sonkorowga (sonkorta dhiigga oo sarreysa oo sababi karta calaamado daran oo u baahan daaweyn degdeg ah); kooma; ama cudurada wadnaha ama beerka. U sheeg dhakhtarkaaga haddii aad qaadanayso acetazolamide (Diamox), dichlorphenamide (Keveyis), methazolamide, topiramate (Topamax, in Qsymia), ama zonisamide (Zonegran).

U sheeg dhakhtarkaaga haddii aad dhawaan isku aragtay mid ka mid ah xaaladaha soo socda, ama haddii aad ku samaysid inta lagu jiro daweynta: infekshan daran; shuban daran, matag, ama qandho; ama haddii aad cabto dareere aad uga yar sidii caadiga ahayd sabab kasta ha noqotee. Waxaa laga yaabaa inaad joojiso qaadashada glyburide iyo metformin ilaa aad ka bogsato.

Haddii aad qalliin ku jirto, oo ay ku jiraan qalliinka ilkaha, ama habraac kasta oo caafimaad oo weyn, u sheeg dhakhtarka inaad qaadanayso glyburide iyo metformin. Sidoo kale, u sheeg dhakhtarkaaga haddii aad qorsheyneyso inaad sameyso wax raajo ah oo dheeh lagugu durayo, gaar ahaan haddii aad cabto ama aad waligaa cabto qamri aad u tiro badan ama aad qabto ama aad qabto cudurka beerka ama wadnaha oo istaaga. Waxaa laga yaabaa inaad u baahato inaad joojiso qaadashada glyburide iyo metformin qalliinka ka hor oo aad sugto 48 saacadood si aad dib ugu bilowdo daaweynta. Dhakhtarkaaga ayaa kuu sheegi doona waqtiga saxda ah ee aad joojinayso qaadashada glyburide iyo metformin iyo goorta aad bilaabayso qaadashada mar kale.

Haddii aad isku aragto mid ka mid ah calaamadaha soo socda, jooji qaadashada glyburide iyo metformin isla markaana wac dhakhtarkaaga isla markiiba: daal aad u daran, daciifnimo, ama raaxo-darro; lallabbo matagid; calool xanuun; rabitaanka cuntada oo yaraaday; neefsi qoto dheer oo dhakhso ah ama neef gaabis ah; dawakhaad; madax wareer; garaaca wadnaha oo dhakhso ah ama gaabis ah; xoqidda maqaarka; muruq xanuun; ama aad ku dareemaysid qabow gacmahaaga ama cagahaaga.

U sheeg dhakhtarkaaga haddii aad si joogto ah u cabto aalkolo ama mararka qaarkood aad u cabto khamri fara badan waqti gaaban (cabbitaanka badan). Cabitaanka aalkoladu waxay kordhisaa halista aad ugu jirtid lactic acidosis ama waxay sababi kartaa hoos udhaca sonkorta dhiiga. Isticmaalka aalkolada inta aad qaadanaysid glyburide iyo metformin sidoo kale marar dhif ah ayaa sababi kara astaamo sida dheecaanka (wajiga oo casaan), madax xanuun, lallabbo, matag, xabad xanuun, daciifnimo, araga oo xumaada, jahwareer maskaxeed, dhidid, ciiqasho, neefsashada oo dhib ah, iyo walwal. Weydii dhakhtarkaaga inta aalkolo ee nabdoon ee la cabi karo inta aad qaadanaysid glyburide iyo metformin.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa baaritaano gaar ah kahor iyo inta lagu jiro daaweynta si loo hubiyo sida wanaagsan ee kilyahaaga u shaqeynayaan iyo jawaabta jirkaaga ee glyburide iyo metformin. Takhtarkaaga kala hadal halista qaadashada glyburide iyo metformin.

Isku darka glyburide iyo metformin waxaa loo isticmaalaa in lagu daaweeyo nooca 2aad ee sonkorowga (xaalad jirku uusan u isticmaalin insulin si caadi ah sidaas darteedna uusan xakamayn karin qadarka sonkorta dhiiga ku jirta) ee dadka sonkorowgooda aan lagu xakamayn karin cuntada iyo jimicsiga kaligood. Glyburide waxay ka tirsan tahay nooc daroogo ah oo loo yaqaan sulfonylureas, metformin-na waxay ku jirtaa nooc daroogo ah oo loo yaqaan biguanides. Glyburide wuxuu yareeyaa sonkorta dhiiga isagoo sababaya xammeetida inay soo saarto insulin (walax dabiici ah oo loo baahan yahay si loo jajabiyo sonkorta jirka) waxayna ka caawisaa jirka inuu u isticmaalo insulin si hufan. Daawadani waxay kaliya ka caawin doontaa yareynta sonkorta dhiigga dadka jirkoodu soo saaro insulin si dabiici ah. Metformin wuxuu ka caawiyaa jirkaaga inuu xakameeyo qadarka gulukoosta (sonkorta) dhiigaaga ku jirta. Waxay hoos u dhigeysaa xaddiga gulukooska aad ka nuugayso cuntadaada iyo xaddiga gulukoosta ee beerkaagu sameeyo. Waxay kaloo ka caawisaa jirkaaga inuu u isticmaalo insulin u gaar ah si wax ku ool ah. Glyburide iyo metformin looma isticmaalo in lagu daaweeyo nooca 1aad ee sonkorowga (xaalad jidhku aanu soo saarin insulin oo markaa ma xakamayn karo qadarka sonkorta ee dhiiga ku jirta) ama ketoacidosis ee sonkorowga (xaalad halis ah oo dhici karta haddii aan la daweyn sonkorta dhiigga ee sareeya) ).

Isku-darka Glyburide iyo metformin wuxuu u yimaadaa kiniin afka laga qaato. Caadi ahaan waxaa la qaataa hal ilaa laba jeer maalintii iyadoo la cunayo. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado glyburide iyo metformin sida saxda ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

Dhakhtarkaagu wuxuu kuugu bilaabi doonaa qadar yar oo ah glyburide iyo metformin waxaana laga yaabaa inuu si tartiib tartiib ah u kordhiyo qiyaastaada, ugu badnaan hal mar 2dii toddobaadba. iyadoo kuxiran jawaabtaada. Si dhaw ula soco gulukoosta dhiiggaaga.

Isku-darka 'Glyburide' iyo 'metformin' isku-darka ayaa xakameeya cudurka macaanka laakiin ma daaweynayo. Sii wad inaad qaadato glyburide iyo metformin xitaa haddii aad caafimaad qabtid. Ha u joojin qaadashada glyburide iyo metformin adigoon dhaqtarkaaga la hadlin.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Daawadan ayaa mararka qaarkood loo qoraa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada glyburide iyo metformin,

• u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad xasaasiyad ku leedahay glyburide, metformin, wax ka mid ah waxyaabaha ku jira glyburide iyo kiniiniyada metformin, ama daawooyin kale. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga haddii aad qaadanaysid bosentan (Tracleer). Dhakhtarkaagu wuxuu kuu sheegi karaa inaadan qaadan glyburide haddii aad qaadanaysid dawadan.
• u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: amiloride (Midamor); angiotensin-converting enzyme (ACE) inhibitors sida benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (in Zestoretic), moexipril (Univasc), perindopril (Aceon), quina , ramipril (Altace), iyo trandolapril (Mavik); daawooyinka xinjirowga lidka ku ah ('khafiifiyeyaasha dhiigga') sida warfarin (Coumadin, Jantoven); asbiriin ama dawooyin kale oo aan anti-bararka ka hortag lahayn (NSAIDs) sida ibuprofen (Advil, Motrin) ama naproxen (Aleve, Naprosyn); beta-blockers sida atenolol (Tenormin), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard, Corzide), iyo propranolol (Hemangeol, Inderal, InnoPran); kaalsiyamka xanibaadayaasha sida amlodipine (Norvasc), diltiazem (Cardizem, Cartia, Diltzac, kuwa kale), felodipine, isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab CR, Procardia), ama verapamil (Calan, Covera, Verelan, in Tarka); chloramphenicol; cimetidine (Tagamet); clarithromycin (Biaxin, gudaha Prevpac); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); sibibramramide (Norpace); durayaasha ('kaniiniyada biyaha'); fluconazole (Diflucan); fluoxetine (Prozac, Sarafem, Selfemra); furosemide (Lasix); daaweynta beddelka hoormoonka; insulin ama daawooyin kale oo sonkorowga qaba; isoniazid (Laniazid, Rifamate, Rifater); MAO xakameeyayaasha sida isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), iyo tranylcypromine (Parnate); daawooyinka xasaasiyadda, neefta, iyo hargabka; daawooyinka cudurada maskaxda iyo lallabbada; miconazole (Lotrimin, Monistat, kuwa kale); morphine (MS Contin, kuwa kale); niacin; p-pillerka (kaniiniyada xakameynta dhalmada); steroids-ka afka laga qaato sida dexamethasone, methylprednisolone (Medrol), iyo prednisone (Rayos); phenytoin (Dilantin, Phenytek); probenecid (Benemid, oo ku taal Colbenemid); procainamide; quinidine (oo ku taal Nuedexta); quinine; antibiyootikada quinolone iyo fluoroquinolone sida cinoxacin (oo aan hadda laga helin Mareykanka, Cinobac), ciprofloxacin (Cipro), enoxacin (oo aan hadda laga helin Mareykanka, Penetrex), gatifloxacin, levofloxacin (Levaquin), lomefloxacin (oo aan hadda laga heli karin Mareykanka) , Maxaquin), moxifloxacin (Avelox), nalidixic acid (oo aan hadda laga helin Mareykanka, NegGram), norfloxacin (oo aan hadda laga helin Mareykanka, Noroxin), ofloxacin (oo aan hadda laga helin Mareykanka, Floxin), sparfloxacin laga heli karo Mareykanka, Zagam), trovafloxacin iyo isku darka alatrofloxacin (oo aan hadda laga heli karin Mareykanka, Trovan); ranitidine (Zantac); rifampin; salicylate xanuun joojiyeyaasha sida choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal, magnesium salicylate (Doan’s, kuwa kale), ama salsalate (Argesic, Disalcid, Salgesic); antibiyootikada sulfa sida cotrimoxazole (Bactrim, Septra); sulfasalazine (Azulfidine); daawooyinka tayroodhka; triamterene (Dyrenium, gudaha Maxzide, kuwa kale); trimethoprim (Primsol, gudaha Bactrim, Septra); ama vancomycin (Vancocin, kuwa kale).
• marka lagu daro xaaladaha ku taxan qaybta DIGNIIN MUHIIM AH, u sheeg dhakhtarkaaga haddii adiga ama qof ka mid ah xubnaha qoyskaaga uu leeyahay ama aad waligiin qabeen yaraanta G6PD (xaalad la iska dhaxlo oo sababi karta waqti hore burburinta unugyada dhiigga cas ama hemolytic anemia); sidoo kale u sheeg dhakhtarkaaga haddii aad leedahay ama waligaa aad qabtid cilado hormoon oo ku lug leh adrenal, pituitary, ama qanjirka 'thyroid'; ama mid daran ama joogto ah oo dheef-shiid kiimikaad ah.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanaysid glyburide iyo metformin, wac dhakhtarkaaga.
• qorsheyso inaad iska ilaaliso soo-gaadhista qorraxda aan loo baahnayn ama daba dheeraatay iyo inaad xidhato dhar ilaaliya, muraayadaha indhaha, iyo muraayadda qorraxda. Glyburide iyo metformin ayaa laga yaabaa inay maqaarkaaga u nuglaadaan iftiinka qoraxda.
• u sheeg dhakhtarkaaga haddii aad wax yar cuntid ama aad jimicsi ka badan intii caadiga ahayd. Tani waxay saameyn ku yeelan kartaa sonkorta dhiiggaaga. Dhakhtarkaaga ayaa ku siin doona tilmaamo haddii tani dhacdo.

Hubso inaad raacdo dhammaan jimicsiga iyo talooyinka cuntada ee dhakhtarkaagu ama nafaqeeyahaagu kuu qoro. Waa muhiim in la cuno cunto caafimaad leh.

Kahor intaadan bilaabin qaadashada glyburide iyo metformin, weydii dhakhtarkaaga waxa la sameeyo haddii aad ilowdo inaad qaadato qadar ama si shil ah aad u qaadato qadar dheeraad ah. Qor tilmaamahan si aad mar dambe ugu tixraaci karto iyaga.

Sida caadiga ah, qaado qiyaasta la seegay isla marka aad xusuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaasta xigta, ka bood qiyaasta la seegay oo sii wad jadwalka daawadaada caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Dawadani waxay sababi kartaa isbeddel ku dhaca sonkorta dhiiggaaga. Waa inaad ogaataa astaamaha sonkorta dhiiga oo hooseysa iyo kuwa sare iyo waxa la sameeyo haddii aad leedahay astaamahan.

Glyburide iyo metformin waxay sababi karaan waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• calool xanuun
• lallabbo ama matagid
• shuban
• dawakhaad

Haddii aad isku aragto mid ka mid ah astaamaha soo socda ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, isla markiiba wac dhakhtarkaaga:

• xabad xanuun
• finan
• hurdi maqaarka ama indhaha
• saxaro midab khafiif ah leh
• kaadi madow
• xanuun qeybta kore ee midig ee caloosha
• dhiigbax ama nabar aan caadi ahayn
• qandho
• cune xanuun
• bararka indhaha, wejiga, dibnaha, carrabka, ama cunaha

Hal daraasad, dadka qaatay daawo la mid ah glyburide si loo daweeyo sonkorowgooda waxay u dhowdahay inay u dhintaan dhibaatooyinka wadnaha marka loo eego dadka lagu daweeyay insulin-ta iyo isbedelka cuntada.

Glyburide iyo metformin waxay sababi karaan waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi heerkulka qolka oo ka fog iftiinka, kuleylka xad-dhaafka ah, iyo qoyaanka (ha ku jirin musqusha).

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara astaamaha hypoglycemia iyo sidoo kale kuwa soo socda:

• qalal
• miyir beelid
• daal xad dhaaf ah
• daciifnimo
• raaxo la'aan
• matagid
• lallabbo
• calool xanuun
• rabitaanka cuntada oo yaraaday
• neefsasho qoto dheer, degdeg ah
• neefta oo ku qabata
• dawakhaad
• madax wareer
• aan caadi ahayn dhakhso ama garaaca wadnaha oo gaabis ah
• maqaarka oo fuuq baxa
• murqo xanuun
• dareemid qabow

Dhakhtarkaaga ayaa kuu sheegi doona sida loo hubiyo jawaabtaada glyburide iyo metformin adiga oo gurigaaga ku cabbiraya heerarka sonkorta dhiiggaaga. Si taxaddar leh u raac tilmaamahaas.

Waa inaad marwalba xidhataa jijin aqoonsiga kaadi macaanka si loo hubiyo inaad hesho daaweyn sax ah markay tahay xaalad degdeg ah.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Isku-darka^® (waxaa ku jira Glyburide, Metformin)