Tijaabada Alpha-Fetoprotein (AFP)
Qanacsan
- Waa maxay baaritaanka alfa-fetoprotein (AFP)?
- Maxaa loo adeegsadaa?
- Maxaan ugu baahanahay baaritaanka AFP?
- Maxaa dhacaya inta lagu jiro baaritaanka AFP?
- Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?
- Ma jiraan wax khatar ah oo imtaxaanku leeyahay?
- Maxay natiijooyinka ka dhigan yihiin?
- Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado baaritaanka AFP?
- Tixraacyo
Waa maxay baaritaanka alfa-fetoprotein (AFP)?
Alpha-fetoprotein (AFP) waa borotiin laga soo saaro beerka uurjiifka soo koraya. Inta lagu jiro koritaanka ilmaha, qaar ka mid ah wakaaladda AFP waxay soo martaa mandheerta waxayna galeysaa dhiiga hooyada. Tijaabada AFP waxay cabireysaa heerka AFP ee haweenka uurka leh inta lagu jiro saddexda bilood ee labaad ee uurka. In badan ama aad u yar AFP oo ku jirta dhiigga hooyada ayaa laga yaabaa inay calaamad u tahay cillad dhalasho ama xaalad kale. Kuwaas waxaa ka mid ah:
- Cilad ku timaadda neerfaha, xaalad halis ah oo keenta koritaan aan caadi ahayn maskaxda ilmaha horumarinaya iyo / ama lafdhabarta
- Cilladda Down syndrome-ka, cilladda hidde-sidaha ee sabata naafonimada caqliga iyo dib u dhaca koritaanka
- Mataano ama dhalasho badan, maxaa yeelay in kabadan hal cunug ayaa soo saara AFP
- Xisaabinta taariikhda la filayo, maxaa yeelay heerarka AFP way is beddelaan xilliga uurka
Magacyada kale: AFP Maternal; Maternal Serum AFP; shaashadda msAFP
Maxaa loo adeegsadaa?
Tijaabada dhiigga ee loo yaqaan 'AFP' waxaa loo adeegsadaa in lagu hubiyo uur jiifka soo koraya halista cilladaha dhalashada iyo cilladaha hidda-socodka, sida cilladaha tuubada neerfaha ama cilladda Down syndrome.
Maxaan ugu baahanahay baaritaanka AFP?
Ururka Uurka Mareykanka ayaa sheegay in dhammaan haweenka uurka leh la siiyo baaritaanka AFP mararka qaar inta u dhexeysa usbuuca 15aad iyo 20aad ee uurka. Baaritaanka waxaa laga yaabaa in si gaar ah lagula taliyo haddii aad:
- Hayso taariikh qoys oo cilladaha dhalashada ah
- Aad tahay 35 sano ama ka weyn
- Aad qabto sonkorow
Maxaa dhacaya inta lagu jiro baaritaanka AFP?
Xirfadlaha daryeelka caafimaadka ayaa tijaabo dhiig ka qaadi doona xididka gacantaada, isagoo isticmaalaya cirbad yar. Kaddib cirbada la geliyo, qadar yar oo dhiig ah ayaa lagu ururin doonaa tuubada baaritaanka ama fijaan. Waxaa laga yaabaa inaad dareento xoog wax yar ah markii irbadda ay soo galayso ama ay ka baxeyso. Tani badanaa waxay qaadataa in ka yar shan daqiiqo.
Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?
Uma baahnid wax diyaarin gaar ah oo loogu talagalay baaritaanka AFP.
Ma jiraan wax khatar ah oo imtaxaanku leeyahay?
Khatar aad u yar ayaa adiga ama cunuggaaga ugu jirta baaritaanka dhiigga ee AFP. Waxaa laga yaabaa inaad xanuun yar ama nabar ku yeelato barta irbadda lagu muday, laakiin astaamaha badankood si dhakhso leh ayey u baxaan. Tijaabad kale oo loo yaqaan 'amniocentesis' ayaa bixisa ogaanshaha saxda ah ee cilladda Down syndrome iyo cilladaha kale ee dhalashada, laakiin baaritaanka wuxuu leeyahay khatar yar oo sababi karta dhicin.
Maxay natiijooyinka ka dhigan yihiin?
Haddii natiijooyinkaagu muujiyaan inay ka sarreeyaan heerarka caadiga ah ee AFP, waxay macnaheedu noqon kartaa in ilmahaagu uu leeyahay cillad dhuunta neerfaha ah sida laf-dhabarka lafdhabarta, xaalad ah in lafaha lafdhabarta aysan ka xirmin agagaarka laf-dhabarka, ama anencephaly, xaalad maskaxdu si hagaagsan uma kobocdo.
Haddii natiijooyinkaagu muujiyaan wax ka hooseeya heerarka caadiga ah ee AFP, waxay noqon kartaa in ilmahaagu qabo cillad hidde sida cilladda Down syndrome, xaalad sababa dhibaatooyin maskaxeed iyo koritaan.
Haddii heerarkaaga AFP aysan caadi ahayn, macnaheedu maahan inay dhibaato ka jirto ilmahaaga. Waxay macnaheedu noqon kartaa inaad dhaleyso wax kabadan hal cunug ama taariikhdaada dhalmada ay qaldan tahay. Waxa kale oo laga yaabaa inaad hesho natiijo been-togan. Taasi waxay ka dhigan tahay in natiijooyinkaagu ay muujinayaan dhibaato, laakiin ilmahaagu waa caafimaad qabaa. Haddii natiijooyinkaagu muujiyaan heer ka hooseeya ama ka hooseeya heerka caadiga ah ee AFP, waxaad u badan tahay inaad heli doontid baaritaanno dheeri ah oo kaa caawinaya sameynta cudurka.
Wax badan ka baro baaritaanka shaybaarka, kala duwanaanshaha tixraaca, iyo fahamka natiijooyinka.
Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado baaritaanka AFP?
Imtixaannada AFP badanaa waa qeyb ka mid ah taxanaha baaritaannada uurka kahor oo loo yaqaanno sumadeeyaal badan ama shaashado saddex-laab ah. Marka lagu daro AFP, baaritaan saddex-laab ah ayaa waxaa ka mid ah baaritaanka hCG, hormoon ay soo saarto mandheerta, iyo estriol, waa nooc ka mid ah estrogen-ka uu sameeyo uurjiifka. Tijaabooyinkani waxay kaa caawin karaan baaritaanka cudurka Down syndrome iyo cilladaha kale ee hidde-sidaha.
Haddii aad halis sare ugu jirto inaad dhasho ilmo leh cilladaha dhalashada qaarkood, adeeg bixiyahaagu sidoo kale wuxuu kugula talin karaa baaritaan cusub oo loo yaqaan 'DNA-cell-free' (cfDNA). Kani waa baaritaan dhiig oo la bixin karo horaanta 10-kath usbuuca uurka. Waxay muujin kartaa inay muujin karto haddii ilmahaagu leeyahay fursad sare oo ah inuu yeesho cilladda Down syndrome ama cudurro kale oo hidde ah.
Tixraacyo
- Ururka Uurka Mareykanka [Internet]. Irving (TX): Ururka Uurka ee Mareykanka; c2017. Baaritaanka Maternal Serum Alpha-Fetoprotein Screening (MSAFP) [waa la cusbooneysiiyay 2016 Sep 2; daliishaday 2017 Jun 5]; [ilaa 3 shaashad]. Waxaa laga heli karaa: http://americanpregnancy.org/prenatal-testing/maternal-serum-alpha-fetoprotein-screening
- Ururka Uurka Mareykanka [Internet]. Irving (TX): Ururka Uurka ee Mareykanka; c2017. Imtixaanka Shaashadda Triple [cusbooneysiiyay 2016 Sep 2; daliishaday 2017 Jun 5]; [ilaa 3 shaashad]. Waxaa laga heli karaa: http://americanpregnancy.org/prenatal-testing/triple-screen-test/
- Qabuuraha JC, Miller KE, Iibiyaasha AD. Baadhitaanka Uurka ee Uurka Hooyada iyo Dhallaanka. Am Fam Dhakhtarka [Internet]. 2002 Mar 1 [daliishaday 2017 Jun 5]; 65 (5): 915–921. Waxaa laga heli karaa: https://www.aafp.org/afp/2002/0301/p915.html
- Johns Hopkins Medicine [Internetka]. Johns Hopkins Daawada; Maktabadda Caafimaadka: Tijaabooyinka guud inta lagu jiro Uurka [la sheegay 2017 Jun 5]; [ilaa 3 shaashad]. Waxaa laga heli karaa: http://www.hopkinsmedicine.org/healthlibrary/conditions/adult/pregnancy_and_childbirth/common_tests_during_pregnancy_85,p01241
- Tijaabooyinka Shaybaarka ee Internetka [Internetka] Washington DC: Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2019. Baadhitaanka Dhiigga Hooyada, Muddada Labaad; [cusboonaysiiyay 2019 Meey 6; daliishaday 2019 Jun 4]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/tests/maternal-serum-screening-second-trimester
- Tijaabooyinka Shaybaarka ee Internetka [Internetka] Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2017. Qaamuuska ereyga: Spina Bifida [oo la soo xigtay 2017 Jun 5]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/glossary/spina-bifida
- Nooca Merck Manual Consumer Version [Internet]. Kenilworth (NJ): Shirkadda Merck & Co. c2017. Tijaabinta Uur-qaadista Uur-qaadista [la cusbooneysiiyay 2017 Jun; daliishaday 2019 Juun 4]; [ilaa 3 shaashad]. Waxaa laga heli karaa: http://www.merckmanuals.com/home/women-s-health-issues/detection-of-genetic-disorders/prenatal-diagnostic-testing
- Xarunta Qaranka ee Horumarinta Cilmiga Tarjumaadda / Xarunta Macluumaadka Cudurada Hiddaha iyo Dhif [Internet]. Gaithersburg (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Ciladaha Tuulada Neural-ka [cusbooneysiiyay 2013 Nov 6; daliishaday 2017 Jun 5]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://rarediseases.info.nih.gov/diseases/4016/neural-tube-defects
- Machadka Wadnaha, Sambabka, iyo Machadka Dhiiga [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Maxay Yahay Khataraha Dhiigga? [la cusboonaysiiyay 2012 Jan 6; daliishaday 2017 Jun 5]; [ilaa 5 shaashad]. Waxaa laga heli karaa: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
- Machadka Wadnaha, Sambabka, iyo Machadka Dhiiga [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Waxa Laga Filayo Baaritaanka Dhiiga [la cusbooneysiiyay 2012 Jan 6; daliishaday 2017 Jun 5]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://www.nhlbi.nih.gov/health-topics/blood-tests
- Jaamacadda Rochester Medical Center [Internet]. Rochester (NY): Jaamacadda Rochester Medical Center; c2017. Encyclopedia Caafimaadka: Alpha-fetoprotein (AFP) [daliishaday 2017 Jun 5]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid;=P02426
- Jaamacadda Rochester Medical Center [Internet]. Rochester (NY): Jaamacadda Rochester Medical Center; c2017. Encyclopedia Health: Alpha-fetoprotein (Dhiig) [daliishaday 2017 Jun 5]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=alpha_fetoprotein_maternal_blood
- Caafimaadka UW [Internetka]. Madison (WI): Jaamacadda Wisconsin Isbitaalada iyo Maamulka Rugta; c2017. Macluumaadka Caafimaadka: Alpha-Fetoprotein (AFP) oo Dhiig ku jira [cusbooneysiiyay 2016 Jun 30; daliishaday 2017 Jun 5]; [ilaa 5 shaashad]. Waxaa laga heli karaa: https://www.uwhealth.org/health/topic/medicaltest/alpha-fetoprotein-afp-in-blood/hw1663.html
- Caafimaadka UW [Internetka]. Madison (WI): Jaamacadda Wisconsin Isbitaalada iyo Maamulka Rugta; c2017. Macluumaadka Caafimaadka: Baaritaanka Saddex-geesoodka ama Quad-ka ee Ciladaha Dhalashada daliishaday 2017 Jun 5]; [ilaa 5 shaashad]. Waxaa laga heli karaa: https://www.uwhealth.org/health/topic/special/maternal-serum-triple-or-quadruple-screening-test/ta7038.html#ta7038-sec
Macluumaadka ku yaal boggan waa in aan loo isticmaalin beddel daryeel caafimaad oo xirfad leh ama talo. La xiriir bixiye daryeel caafimaad haddii aad su'aalo ka qabtid caafimaadkaaga.