Cudurka 'Psoriatic arthritis'

Cudurka 'Psoriatic arthritis' waa dhibaato wadajir ah (arthritis) oo badanaa ku dhacda xaalad maqaarka loo yaqaan 'psoriasis'.

Cudurka cudurka loo yaqaan 'Psoriasis' waa dhibaato guud oo maqaarka ku dhacda taasoo keenta in maqaarku maqaar cas yeesho. Waa xaalad sii socota (daba-dheeraatay) caabuq. Cudurka 'Psoriatic arthritis' wuxuu ku dhacaa qiyaastii 7% ilaa 42% dadka qaba cudurka psoriasis. Ciddiyaha cudurka psoriasis ee ciddiyaha ayaa lala xiriiriyaa cudurka loo yaqaan 'psoriatic arthritis'.

Xaaladaha badankood, cudurka psoriasis wuxuu yimaadaa kahor arthritis-ka. Dad yar, arthritis-ku wuxuu yimaadaa kahor cudurka maqaarka. Si kastaba ha noqotee, inaad yeelato cudurka daran ee faafitaanka badan ee cudurka 'psoriasis' wuxuu umuuqdaa mid kordhinaya fursadda qaadista cudurka 'psoriatic arthritis'.

Lama oga sababta keenta cudurka loo yaqaan 'psoriatic arthritis'. Hidda-wadaha, habka difaaca jirka, iyo arrimaha deegaanka ayaa door ka ciyaari kara. Waxay u badan tahay in maqaarka iyo cudurada kalagoysyadu ay sababo isku mid ah yeelan karaan. Si kastaba ha noqotee, lagama yaabo inay wada dhacaan.

Arthritis-ku wuxuu noqon karaa mid fudud oo ku lug yeelan kara xoogaa kala-goysyada ah. Kala-goysyada dhamaadka faraha ama suulasha ayaa laga yaabaa inay saameyn badan yeeshaan. Cudurka 'Psoriatic arthritis' inta badan waa sinnaan la'aan wuxuuna keenaa arthritis kaliya hal dhinac oo jirka ah.

Dadka qaarkood, cudurku wuxuu noqon karaa mid daran oo wuxuu ku dhacaa kalagoysyo badan, oo ay ku jiraan lafdhabarta. Astaamaha laf dhabarta waxaa ka mid ah qallafsanaan iyo xanuun. Waxay badanaa ku dhacaan lafdhabarta hoose iyo sacrum.

Dadka qaarkood ee qaba cudurka 'psoriatic arthritis' waxay yeelan karaan barar indhaha.

Waqtiga intiisa badan, dadka qaba cudurka 'psoriatic arthritis' waxay leeyihiin maqaarka iyo is beddelada ciddiyaha ee cudurka psoriasis. Badanaa, maqaarku wuu ka sii daraa isla waqtigaas isla markaana uu ku dhaco arthritis-ku.

Tendons ayaa laga yaabaa inay ku bararaan psoriatic arthritis. Tusaalooyinka waxaa ka mid ah muruqyada 'Achilles tendon', 'plantar fascia', iyo galka gacmaha oo gacanta ku jira.

Inta lagu jiro baaritaanka jirka, bixiyaha xanaanada caafimaadka ayaa eegi doona:

• Barar wadajir ah
• Jirka maqaarka (cudurka psoriasis) iyo daloolinta ciddiyaha
• Danqasho
• Caabuq indhaha ku dhaca

Raajooyin wadajir ah ayaa la samayn karaa.

Ma jiraan baaritaanno dhiig oo gaar ah oo lagu ogaanayo cudurka psoriatic arthritis ama cudurka psoriasis. Tijaabooyin looga saarayo noocyada kale ee arthritis-ka waa la sameyn karaa:

• Cudurka rheumatoid
• Kahortagayaasha anti-CCP

Bixiyaha ayaa laga yaabaa inuu baaro hidda-wade loo yaqaan HLA-B27 Dadka ku lugta leh dhabarka waxay u badan tahay inay yeeshaan HLA-B27.

Bixiyaha ayaa laga yaabaa inuu ku siiyo daawooyinka non-steroid anti-bararka (NSAIDs) si loo yareeyo xanuunka iyo bararka kalagoysyada.

Arthritis-ka aan ku fiicnayn NSAIDs wuxuu u baahan doonaa in lagu daaweeyo daawooyinka loo yaqaan daawooyinka antirheumatic-ka-beddelaya cudurka (DMARDs). Kuwaas waxaa ka mid ah:

• Methotrexate
• Leflunomide
• Sulfasalazine

Apremilast waa daawo kale oo loo isticmaalo daaweynta cudurka psoriatic arthritis.

Daawooyinka cusub ee bayoolojiga ayaa waxtar u leh xanuunka 'psoriatic arthritis' ee aan lagu xakamaynin DMARDs. Daawooyinkani waxay xannibiyaan borotiin loo yaqaanno buro necrosis factor (TNF). Badanaa waxay waxtar u leeyihiin cudurka maqaarka iyo cudurka wadajirka ah ee cudurka psoriatic arthritis. Daawooyinkaan waxaa lagu bixiyaa cirbad.

Daawooyin kale oo cusub oo bayoolaji ah ayaa loo heli karaa in lagu daaweeyo xanuunka 'psoriatic arthritis' ee ku socda xitaa isticmaalka DMARDs ama wakiilada anti-TNF. Daawooyinkaan sidoo kale waxaa lagu bixiyaa cirbad.

Kalagoysyada oo aad u xanuun badan ayaa lagu daaweyn karaa irbado steroid ah. Kuwani waxaa loo isticmaalaa marka mid ama dhawr qaybood oo keliya ay ku lug yeeshaan. Khabiirada badankood kuma talinayaan corticosteroids afka ah ee loo yaqaan 'psoriatic arthritis'. Isticmaalkoodu wuu ka sii dari karaa cudurka psoriasis wuxuuna faragelin ku yeelan karaa saameynta daroogooyinka kale.

Marar dhif ah, qalliin ayaa loo baahan karaa si loo dayactiro ama loo beddelo kalagoysyada dhaawacmay.

Dadka qaba caabuqa isha waa inay arkaan dhakhtarka indhaha.

Bixiyahaagu wuxuu soo jeedin karaa isku-dar nasasho iyo jimicsi ah. Daaweynta jireed waxay gacan ka geysan kartaa kordhinta dhaqdhaqaaqa wadajirka ah. Waxaad sidoo kale isticmaali kartaa kuleylka iyo daaweynta qabowga.

Cudurku mararka qaar wuu khafiif yahay wuxuuna ku dhacaa oo keliya kala-goysyada yar. Si kastaba ha noqotee, dad badan oo qaba xanuunka 'psoriatic arthritis' ee dhaawaca xubnaha ayaa dhacda dhowrka sano ee ugu horreeya. Dadka qaarkiis, arthritis aad u xun ayaa laga yaabaa inuu ku keeno cilladaha gacmaha, cagaha, iyo lafdhabarta.

Inta badan dadka qaba cudurka 'psoriatic arthritis' ee aan ku fiicnayn NSAIDs waa inay u tagaan dhakhtarka rheumatologist, takhasus ku leh arthritis, oo ay weheliyaan dhakhtarka maqaarka ee cudurka psoriasis.

Daaweynta hore waxay yareyn kartaa xanuunka waxayna ka hortagi kartaa dhaawaca wadajirka ah, xitaa xaaladaha aadka u xun.

Wac daryeel bixiyahaaga haddii aad isku aragto astaamaha arthritis oo ay weheliso cudurka psoriasis.

Arthritis - psoriatic; Psoriasis - cudurka psoriatic arthritis; Spondyloarthritis - cudurka psoriatic arthritis; PsA

• Psoriasis - guttate on gacmaha iyo xabadka
• Psoriasis - guttate dhabanka

Bruce IN, Ho PYP. Tilmaamaha caafimaadka ee cudurka 'psoriatic arthritis'. Gudaha: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. 7aad ed. Philadelphia, PA: Elsevier; 2019: cutubka 128.

Gladman D, Rigby W, Azevedo VF, et al. Tofacitinib oo loogu talagalay cudurka 'psoriatic arthritis' ee bukaannada qaba jawaab aan ku filnayn ee ka hortagga TNF. N Engl J Med. 2017; 377:1525-1536.

Smolen JS, Schöls M, Braun J, iyo al. Daweynta laf-dhabarka 'spondyloarthritis' iyo 'spondyloarthritis', gaar ahaan psoriatic arthritis, si loo bartilmaameedsado: 2017 cusbooneysiinta talooyinka ee kooxda hawlgalka caalamiga ah. Ann Rheum Dis. 2018; 77 (1): 3-17. PMID: 28684559 pubmed.ncbi.nlm.nih.gov/28684559/.

Veale DJ, Orr C. Maareynta cudurka 'psoriatic arthritis'. Gudaha: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. 7aad ed. Philadelphia, PA: Elsevier; 2019: cutubka 131.