Eosinophilic fasciitis

Eosinophilic fasciitis (EF) waa cilad ku jirta unugyada maqaarka hoostiisa iyo muruqa dushiisa, oo loo yaqaanno fascia, ayaa barara, barara oo qaro. Maqaarka gacmaha, lugaha, qoorta, caloosha ama cagaha si dhakhso leh ayuu u barari karaa. Xaaladda ayaa aad u yar.

EF waxay umuuqataa mid la mid ah scleroderma, laakiin lama xiriiro. Si ka duwan sida scleroderma, ee EF, faraha kuma jiraan.

Sababta EF lama yaqaan. Kiisas dhif ah ayaa dhacay ka dib markii la qaatay daawooyinka L-tryptophan. Dadka qaba xaaladdan, unugyada dhiigga cad, oo loo yaqaan 'eosinophils', waxay ku soo baxaan muruqyada iyo unugyada. Eosinophils waxay kuxirantahay falcelinta xasaasiyadda. Cilladda cillad-xanuunku waxay ku badan tahay dadka da'doodu tahay 30 illaa 60 jir.

Calaamadaha waxaa ka mid noqon kara:

• Jilicsanaan iyo barar maqaarka ah oo ku dhaca gacmaha, lugaha, ama mararka qaarkood kala-goysyada (badiyaa labada dhinac ee jirka)
• Arthritis
• Cudurka 'tunpal tunnel syndrome'
• Murqo xanuun
• Maqaarka qaro leh oo umuuqda mid jilicsan

Tijaabooyinka la qaadi karo waxaa ka mid ah:

• CBC leh kala duwanaansho
• Gamma globulins (nooc ka mid ah borotiinka habka difaaca jirka)
• Qiyaasta qanjirka 'Erythrocyte' (ESR)
• MRI
• Cad ka-qaadista murqaha
• Cad ka-qaadista maqaarka (kaabsashada ayaa loo baahan yahay in lagu daro unugyada qotada dheer ee fascia)

Corticosteroids iyo dawooyinka kale ee xakameynaya difaaca jirka ayaa loo isticmaalaa in lagu yareeyo calaamadaha. Daawooyinkan ayaa waxtar badan leh markii la bilaabay bilowga cudurka. Daawooyinka nonsteroidal anti-bararka (NSAIDs) ayaa sidoo kale kaa caawin kara yareynta astaamaha.

Xaaladaha badankood, xaaladdu waxay ku baaba'daa 1 illaa 3 sano gudahood. Hase yeeshe, astaamuhu way sii dheeraan karaan ama soo noqon karaan.

Arthritis-ku waa cillad naadir ah oo ah EF. Dadka qaarkiis waxaa laga yaabaa inay ku dhacaan cudurro dhiig oo halis ah ama kansarrada dhiigga la xiriira, sida dhiig la'aanta ama leukemia. Aragtida ayaa aad uga sii xun haddii cudurada dhiiggu dhacaan.

Wac daryeel caafimaad bixiyahaaga haddii aad leedahay astaamo cilladan.

Ma jiro ka hortag la yaqaan.

Shulman syndrome

• Muruqyada hore ee dusha sare

Aronson JK. Tryptophan. Gudaha: Aronson JK, ed. Saamaynta Meyler ee Daroogooyinka. 16aad. Waltham, MA: Elsevier B.V .; 2016: 220-221.

James WD, Elston DM, Daawee JR, Rosenbach MA, Neuhaus IM. Cudurada unugyada isku xidha. Gudaha: James WD, Elston DM, Ku daawee JR, Rosenbach MA, Neuhaus IM, eds. Cudurada Andrews ee maqaarka: Cilmiga maqaarka. 13aad. Philadelphia, PA: Elsevier; 2020: cutubka 8.

Lee LA, Werth VP. Maqaarka iyo cudurada lafaha. Gudaha: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Kelley iyo Firestein's Buugga Buugga Rheumatology. 10aad ed. Philadelphia, PA: Elsevier; 2017: cutubka 43.

Pinal-Fernandez I, Selva-O ’Callaghan A, Grau JM. Cilad-sheegista iyo kala-soocidda fasciitis-ka eosinophilic. Autoimmun Rev.. 2014; 13 (4-5): 379-382. PMID: 24424187 www.ncbi.nlm.nih.gov/pubmed/24424187.

Ururka Qaranka ee Dhibaatooyinka Nasiibka ah. Eosinophilic fasciitis. rarediseases.org/rare-diseases/eosinophilic-fasciitis/. La cusbooneysiiyay 2016. La helay Maarso 6, 2017.