Sababta XII (Sababta Hageman) yaraanta

Sababta XII yaraanta waa cillad la iska dhaxlo oo saameysa borotiin (factor XII) oo ku lug leh xinjirowga dhiigga.

Markaad dhiig baxdid, falcelinno isdaba joog ah ayaa ku dhaca jirka oo ka caawiya xinjirowga dhiigga inuu sameeyo. Nidaamkan waxaa lagu magacaabaa xinjirowga xiidmaha. Waxay ku lug leedahay borotiinno gaar ah oo loo yaqaan xinjirowga ama arrimaha xinjirowga. Waxaad yeelan kartaa fursad sare oo ah dhiig bax xad-dhaaf ah haddii mid ama in ka badan oo ka mid ah arrimahan la la'yahay ama aan sidii loogu talagalay u shaqeynaynin.

Xaqiiqda XII waa mid ka mid ah qodobadan. Maqnaanshaha qodobkaan kuma sababayo inaad si aan caadi ahayn u dhiig baxdid. Laakiin, dhiiggu wuxuu qaataa in kabadan inta caadiga ah si uu uqasho tuubada baaritaanka.

Sababta XII yaraanta waa cillad naadir ah oo laga dhaxlo.

Badanaa ma jiraan wax calaamado ah.

Yaraanta Factor XII waxaa badanaa la helaa marka tijaabooyinka xinjirowga loo sameeyo baaritaanka joogtada ah.

Tijaabooyinka waxaa ka mid noqon kara:

• Tijaabada Factor XII si loo cabbiro waxqabadka cunsurka XII
• Waqtiga qayb ahaan thromboplastin (PTT) si loo hubiyo inta ay qaadanayso in dhiiggu xinjiroobo
• Daraasad isku dhafan, baaritaan PTT gaar ah si loo xaqiijiyo yaraanta XII

Daaweynta badanaa looma baahna.

Kheyraadkaani waxay bixin karaan macluumaad dheeri ah oo ku saabsan sababaha yaraanta XII:

• Mu'asasada Qaranka ee Hemophilia - www.hemophilia.org/Bleeding-Disorders/Types-of-Bleeding-Disorders/Other-Factor-Deficiencies/Factor-XII
• Ururka Qaranka ee Dhibaatooyinka Nadir - rarediseases.org/rare-diseases/factor-xii-deficiation
• NIH Xarunta Macluumaadka Cudurada Hiddo-wadaha iyo Dhif - rarediseases.info.nih.gov/diseases/6558/factor-xii-deficient

Natiijada ayaa la filayaa inay fiicnaato daaweyn la'aan.

Badanaa ma jiraan wax dhibaatooyin ah.

Bixiyaha xanaanada caafimaadka badanaa wuu ogaadaa xaaladan marka uu wado tijaabooyinka kale ee shaybaarka.

Tani waa cillad la iska dhaxlay. Ma jiro hab la yaqaan oo looga hortago.

Yaraanta F12; Yaraanta cunsuriyada Heman; Dabeecadda Hageman; Yaraanta HAF

• Xinjirowga dhiigga

Gailani D, Wheeler AP, Neff AT. Ciladaha xinjirowga dhifka ah. Gudaha: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Mabaadi'da Aasaasiga ah iyo Tababarka. 7aad ed. Philadelphia, PA: Elsevier; 2018: cutubka 137.

Hoolka JE. Hemostasis iyo xinjirowga dhiigga. Gudaha: Hall JE, ed. Buugga Guyton iyo Hall ee Caafimaadka Jirka. 13aad. Philadelphia, PA: Elsevier; 2016: cutubka 37.

Ragni MV. Ciladaha dhiig baxa: cilladaha xinjirowga ku yaraada. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 25aad. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 174.