ALP baaritaanka isoenzyme

Alkaline phosphatase (ALP) waa enzyme laga helo unugyo badan oo jirka ka mid ah sida beerka, kaadi mareenka, lafaha, iyo xiidmaha. Waxaa jira dhowr nooc oo kaladuwan oo ALP ah oo loo yaqaan isoenzymes. Qaab dhismeedka enzyme waxay kuxirantahay hadba meesha jirka laga soo saaro. Baaritaankaan waxaa badanaa loo adeegsadaa in lagu baaro ALP lagu sameeyay unugyada beerka iyo lafaha.

Baadhitaanka 'ALP isoenzyme' waa tijaabo shaybaar oo cabbiraysa qiyaasaha noocyada kala duwan ee ALP ee dhiigga ku jira.

Imtixaanka ALP waa baaritaan la xiriira.

Sambal dhiig ayaa loo baahan yahay. Inta badan dhiigga waxaa laga soo qaataa xididka ku yaal gudaha xusulka ama dhabarka gacanta.

Waa inaadan wax cunin ama cabin 10 ilaa 12 saacadood baaritaanka ka hor, haddii uusan daryeel caafimaad bixiyahaagu kuu sheegin inaad sidaas sameyso mooyee.

Daawooyin badan ayaa faragelin kara natiijooyinka baaritaanka dhiigga.

• Bixiyahaaga ayaa kuu sheegi doona haddii aad u baahan tahay inaad joojiso qaadashada wax daawooyin ah ka hor baaritaankaan.
• HA JOOJIN ama ha beddelin dawooyinkaaga adiga oo aan marka hore la hadlin takhtarkaaga.

Waxaa laga yaabaa inaad dareento xanuun yar ama qaniinyo markii cirbadda la gelinayo. Waxa kale oo laga yaabaa inaad dareento xoogaa jug ah goobta ka dib markii dhiigga lagaa qaado.

Marka natiijada baaritaanka ALP ay sarreyso, waxaa laga yaabaa inaad u baahato baaritaanka ALP isoenzyme. Tijaabadani waxay gacan ka geysan doontaa go'aaminta qaybta jirka ka mid ah ee sababa heerarka sare ee ALP.

Tijaabadan waxaa loo isticmaali karaa in lagu baaro ama loola socdo:

• Cudurka lafaha
• Beerka, xameetida, ama cudur kaadi haysta
• Xanuun caloosha ah
• Cudurka qanjirka 'parathyroid'
• Faytamiin D yaraanta

Waxaa sidoo kale loo samayn karaa si loo hubiyo shaqada beerka iyo in la arko sida daawooyinka aad u qaadato ay saameyn ugu yeelan karaan beerkaaga.

Qiimaha caadiga ah ee wadarta ALP waa 44 illaa 147 unug caalami ah halkii litir (IU / L) ama 0.73 ilaa 2.45 microkatal halkii litir (µkat / L). Tijaabada ALP isoenzyme waxay yeelan kartaa qiimayaal caadi ah oo kala duwan.

Dadka qaangaarka ah waxay ka hooseeyaan heerarka ALP marka loo eego carruurta. Lafaha wali sii kordhaya waxay soo saaraan heerar sare oo ah ALP. Inta lagu jiro xoogaa koritaanka, heerarku waxay noqon karaan ilaa 500 IU / L ama 835 atKat / L. Sababtaas awgeed, baaritaanka badanaa laguma sameeyo carruurta, natiijooyinka aan caadiga ahayn waxaa loola jeedaa dadka waaweyn.

Natiijooyinka baaritaanka isoenzyme ayaa daaha ka qaadi kara in kororku ku jiro "laf" ALP ama "beer" ALP.

Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Kala hadal adeeg bixiyahaaga macnaha natiijooyinka baaritaankaaga gaarka ah.

Tusaalaha kore wuxuu muujinayaa qiyaasta cabirka guud ee natiijooyinka imtixaanadan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabin karaan tijaabooyin kala duwan.

Heerarka ALP-ka-caadiga ka sarreeya:

• Xannibaadda dhiigga
• Cudurka lafaha
• Cunista cuntada dufanka leh haddii aad leedahay nooca dhiigga O ama B
• Jabka bogsashada
• Cagaarshow
• Hyperparathyroidism
• Leukemia
• Cudurka beerka
• Lymphoma
• Burooyinka lafdhabarta ah
• Osteomalacia
• Cudurka Paget
• Rickets
• Sarcoidosis

Heerarka caadiga ka hooseeya ee ALP:

• Hypophosphatasia
• Nafaqo darrada
• Yaraanta borotiinka
• Cudurka Wilson

Heerarka waxyar uun ka sarreeya inta caadiga ah dhib ma noqon karaan haddii aan laga helin calaamado kale oo cudur ama dhibaato caafimaad ah.

Imtixaanka isoenzyme ee alkali fosfatase

• Baaritaanka dhiigga

Berk PD, Korenblat KM. U dhowaanshaha bukaanka cagaarshow ama baaritaanno aan caadi ahayn oo beerka ah. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 25aad. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 147.

Fogel EL, Sherman S. Cudurada xameetida iyo kaadiheysta xiidmaha. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 25aad. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 155.

Martin P. U dhowaanshaha bukaanka qaba cudurka beerka. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 25aad. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 146.

Weinstein RS. Osteomalacia iyo rickets. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 25aad. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 244.