Antibiyootiko peroxidase

Microsomes waxaa laga helaa gudaha unugyada tayroodhka. Jidhku wuxuu soo saaraa unugyada difaaca jirka ee microsomes markay waxyeello soo gaadho unugyada tayroodhka. Tijaabada antithyroid microsomal antibody waxay cabirtaa unugyadaan dhiiga kujira.
Sambal dhiig ayaa loo baahan yahay.
Marka irbadda la geliyo si dhiig loo qaado, dadka qaar waxay dareemaan xanuun dhexdhexaad ah. Qaar kale waxay dareemaan oo keliya dharbaaxo ama xaniin. Intaas ka dib, waxaa laga yaabaa inay xoogaa wax garaacaan ama nabar yar. Tani dhawaan way tagi doontaa.
Tijaabadani waxaa loo sameeyaa si loo xaqiijiyo waxa sababa dhibaatooyinka tayroodh, oo ay ku jiraan Hashimoto thyroiditis.
Baadhitaanka waxaa sidoo kale loo isticmaalaa in lagu ogaado haddii jir-dhiska jirka ama jir-dil la'aanta ay waxyeeleyso qanjirka 'thyroid'.
Tijaabadada taban micnaheedu waa natiijada waa caadi.
Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabin karaan tijaabooyin kala duwan. Kala hadal bixiyahaaga daryeelka caafimaadka macnaha natiijooyinkaaga gaarka ah ee baaritaanka.
Tijaabada saxda ah waxaa laga yaabaa inay u sabab tahay:
- Granulomatous thyroiditis (fal-celinta jirka ee qanjirka 'thyroid' oo inta badan la socda caabuq xagga sare ah)
- Hashimoto thyroiditis (falcelinta nidaamka difaaca jirka ee qanjirka 'thyroid')
Heerarka sare ee unugyada difaaca jirka ayaa sidoo kale lala xiriiriyay halista sii kordheysa ee:
- Ilmo dhicis
- Preeclampsia (dhiig kar iyo borotiin ku jira kaadida kadib usbuuca 20aad ee uurka)
- Dhalasho degdeg ah
- Dhibaatada bacriminta fitamiinada
Muhiim: Natiijada wanaagsan macnaheedu maahan inaad marwalba qabto xaalad tayroodh ama inaad ubaahantahay daaweyn tayroodhkaaga. Natiijo wax ku ool ah ayaa macnaheedu noqon karaa inaad leedahay fursad sare oo ah inaad ku dhacdo cudurka qanjirka 'thyroid' mustaqbalka. Tani waxay badanaa la xiriirtaa taariikhda qoyska ee cudurka qanjirka 'thyroid'.
Unugyada difaaca jirka ee loo yaqaan 'Antithyroid microsomal antibodies' ayaa laga arki karaa dhiiggaaga haddii aad leedahay xaalado kale oo isdifaaca jirka, oo ay ka mid yihiin:
- Dhiig-yaraanta hemolytic
- Cagaarshowga iswada
- Cudurka 'adrenal disease'
- Rheumatoid arthritis
- Sjögren syndrome
- Nidaamka lupus erythematosus
Khatar yar ayaa ku jirta in dhiigga lagaa qaado. Xididdada iyo halbowlayaasha waxay ku kala duwan yihiin cabirka qof ilaa qof kale iyo dhinac jirka ah ilaa dhinac kale. Helitaanka tijaabada dhiigga ee dadka qaarkiis way ka dhib badan tahay kuwa kale.
Khataraha kale ee la xiriira dhiig qaadashada way yar yihiin laakiin waxaa ka mid noqon kara:
- Dhiigbax xad dhaaf ah
- Miyir beelid ama dareemid madax-wareer
- Daloollo badan si loo helo xididdada
- Hematoma (dhiigbax maqaarka hoostiisa)
- Infekshan (halis yar mar kasta oo maqaarku jabo)
Thyroid antimicrosomal antibody; Antimicrosomal antibody; Microsomal antibody; Antithyroid microsomal antibody; TPOAb; Anti-TPO antibody
Baaritaanka dhiigga
Chang AY, Auchus RJ. Dhibaatooyinka endocrine ee saameeya taranka. Gudaha: Strauss JF, Barbieri RL, eds. Yen & Jaffe’s Endocrinology Taranka. 8aad ed. Philadelphia, PA: Elsevier; 2019: cutubka 24.
Chernecky CC, Berger BJ. Thyroid peroxidase (TPO, antimicrosomal antibody, antithyroid microsomal antibody) antibody - dhiig. Gudaha: Chernecky CC, Berger BJ, eds. Tijaabooyinka Shaybaarka iyo Nidaamyada Baadhista. 6aad ed. St Louis, MO: Elsevier Saunders; 2013: 1080-1081.
Guber HA, Farag AF. Qiimeynta shaqada endocrine. Gudaha: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis iyo Maareynta Hababka Shaybaarka. 23aad ed. St Louis, MO: Elsevier; 2017: cutubka 24.
Salvatore D, Cohen R, Kopp PA, Larsen PR. Cudurka qanjirka 'thyroid' iyo qiimeynta ogaanshaha cudurka. Gudaha: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Buugga Buugga Endocrinology. 14aad. Philadelphia, PA: Elsevier; 2020: cutubka 11.
Weiss RE, Refetoff S. Tijaabinta shaqada qanjirka 'thyroid'. Gudaha: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Dadka waaweyn iyo carruurta. 7aad ed. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 78.