Baadhitaanka borotiinka electrophoresis

Tijaabada borotiinka electrophoresis (UPEP) kaadida waxaa loo isticmaalaa in lagu qiyaaso inta borotiinada qaarkood ku jiraan kaadida.

Muunad kaadi-nadiif ah ayaa loo baahan yahay. Habka nadiif-ka-qabashada waxaa loo isticmaalaa in looga hortago jeermiska xubinta taranka ama xubinta taranka inay galaan sambalka kaadida. Si loo ururiyo kaadidaada, bixiyaha xanaanada caafimaadka ayaa laga yaabaa inuu ku siiyo xirmo gaara oo nadiif ah oo ay kujiraan xal nadiifin ah iyo masaxaad nadiif ah. Raac tilmaamaha si sax ah.

Kaddib marka aad soo qaaddo sambal kaadi ah, waxaa loo dirayaa shaybaarka. Halkaas, takhasuska sheybaarku wuxuu tijaabada kaadida ku ridi doonaa warqad gaar ah wuxuuna mari doonaa koronto dusheeda. Borootiinnada ayaa dhaqaaqa oo sameeya kooxo la arki karo. Kuwani waxay muujinayaan xaddiga guud ee borotiin kasta.

Bixiyahaaga ayaa laga yaabaa inuu kuu sheego inaad joojiso qaadashada daawooyinka qaarkood oo faragelin ku sameyn kara baaritaanka. Daawooyinka saameyn ku yeelan kara natiijooyinka baaritaanka waxaa ka mid ah:

• Chlorpromazine
• Corticosteroids
• Isoniazid
• Neomycin
• Fenacemide
• Baaskiillada
• Sulfonamides
• Tolbutamide

Ha joojin qaadashada wax daawo ah adiga oo aan marka hore lahadlin takhtarkaaga.

Tijaabadani waxay ku lug leedahay oo keliya kaadida caadiga ah. Ma jiraan wax dhib ah.

Caadi ahaan borotiin ma laha, ama qaddar yar oo borotiin ah ayaa ku jira kaadida. Qadar aan caadi ahayn oo ah borotiin ku jira kaadida ayaa calaamad u noqon kara xanuuno badan oo kala duwan.

UPEP ayaa lagugula talin karaa inay kaa caawiso go'aaminta waxa borotiinka ku jira kaadida. Ama waxaa laga yaabaa in loo sameeyo sidii baaritaan baaris ah si loo cabbiro qaddarka kala duwan ee noocyada kala duwan ee borotiinnada ku jira kaadida. UPEP waxay ogaataa 2 nooc oo borotiin ah: albumin iyo globulins.

Qaddar weyn oo globulins ah lagama helo kaadida. Kaadi albumin ka yar 5 mg / dL.

Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabiyaan noocyo kala duwan. Kala hadal dhakhtarkaaga macnaha natiijooyinka baaritaankaaga gaarka ah.

Haddii saamiga kaadida uu leeyahay qaddar weyn oo ah globulins ama ka sarreeya heerka caadiga ah ee albumin, waxay noqon kartaa mid ka mid ah kuwan soo socda:

• Caabuq daran
• Kordhinta borotiinka aan caadiga ahayn ee unugyada iyo xubnaha (amyloidosis)
• Shaqada kilyaha oo yaraatay
• Cudurka kilyaha oo ay ugu wacan tahay kaadi sonkorow (nephropathy sonkorow)
• Kelyaha oo hawl gab
• Nooc kansar dhiig ah oo loo yaqaan myeloma badan
• Kooxda calaamadaha oo ay ku jiraan borotiinka ku jira kaadida, heerka borotiinka ee dhiigga ku yar, barar (nephrotic syndrome)
• Infekshinka kaadi mareenka ee daran

Ma jiraan wax khatar ah oo ka imaan kara baaritaankaan.

Kaadiinka electrophoresis; UPEP; Myeloma badan - UPEP; Waldenström macroglobulinemia - UPEP; Amyloidosis - UPEP

• Nidaamka kaadi-mareenka ragga

Chernecky CC, Berger BJ. Barootiinka electrophoresis - kaadi. Gudaha: Chernecky CC, Berger BJ, eds. Tijaabooyinka Shaybaarka iyo Nidaamyada Baadhista. 6aad ed. St Louis, MO: Elsevier Saunders; 2013: 920-922.

McPherson RA. Borotiin gaar ah. Gudaha: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis iyo Maareynta Hababka Shaybaarka. 23aad ed. St Louis, MO: Elsevier; 2017: cutubka 19.

Rajkumar SV, Dispenzieri A. Myeloma badan iyo xanuunno la xiriira. Gudaha: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6aad ed. Philadelphia, PA: Elsevier; 2020: baab 101.