CSF oligoclonal faashad

Xannibaadda oligoclonal ee CSF waa tijaabo lagu raadinayo borotiinnada la xiriira caabuqa ee dareeraha maskaxda (CSF). CSF waa dheecaanka cad ee ku qulqulaya booska ku wareegsan laf-dhabarka iyo maskaxda.

Qeybaha Oligoclonal waa borotiino loo yaqaan immunoglobulins. Joogitaanka borotiinadani waxay muujineysaa barar ku dhaca habka dhexe ee neerfaha. Joogitaanka kooxo oligoclonal ah ayaa laga yaabaa inay tilmaamaan ogaanshaha cudurka 'sclerosis multiple'.

Muunad CSF ayaa loo baahan yahay. Dalool lumbar (laf-dhabarka laf-dhabarka) ayaa ah habka ugu caamsan ee loo soo qaado shay-baarkan.

Hababka kale ee ururinta CSF si dhif ah ayaa loo isticmaalaa, laakiin mararka qaarkood ayaa lagula talin karaa. Waxaa ka mid ah:

• Daloolinta godka
• Daloolida Hawada
• Ka saarida CSF tuubada horeyba ugu jirtay CSF, sida shuntida ama qashinka wadnaha.

Ka dib sambalka la qaado, waxaa loo diraa shaybaar si loo baaro.

Tijaabadani waxay gacan ka geysaneysaa taageeridda ogaanshaha cudurka sclerosis (MS). Si kastaba ha noqotee, ma xaqiijineyso cudurka. Kooxaha Oligoclonal ee CSF ayaa sidoo kale lagu arki karaa cuduro kale sida:

• Nidaamka lupus erythematosus
• Fayraska difaaca jirka ee dadka (HIV)
• Faalig

Caadi ahaan, mid ama maya guuto waa in laga helaa CSF.

Fiiro gaar ah: Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Kala hadal bixiyahaaga daryeelka caafimaadka macnaha natiijooyinkaaga gaarka ah ee baaritaanka.

Tusaalooyinka kor ku xusan waxay muujinayaan cabirka guud ee natiijooyinka imtixaanadan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabin karaan tijaabooyin kala duwan.

Waxa jira laba ama in ka badan oo faashad ah oo laga helay CSF oo aan ku jirin dhiigga. Tani waxay noqon kartaa calaamad muujinaysa cudurka loo yaqaan 'sclerosis multiple' ama caabuq kale.

Dareeraha Cerebrospinal - tallaalka tallaalka jirka (immunofixation)

• CSF oligoclonal banding - taxane
• Daloolida lumbar (laf-dhabarka)

Deluca GC, Griggs RC. U dhowaanshaha bukaanka qaba cudurka neerfaha. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 26aad. Philadelphia, PA: Elsevier; 2020: cutubka 368.

Karcher DS, McPherson RA. Cerebrospinal, synovial, dheecaannada jirka ee daran, iyo tijaabooyinka kale. Gudaha: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis iyo Maareynta Hababka Shaybaarka. 23aad ed. St Louis, MO: Elsevier; 2017: cutubka 29.