Tijaabada kaadida Cortisol

Tijaabada kaadida cortisol waxay cabirtaa heerka cortisol ee kaadida. Cortisol waa hormoon glucocorticoid (steroid) ah oo ay soo saarto qanjirka 'adrenal gland'.

Cortisol sidoo kale waa lagu cabiri karaa iyadoo la adeegsanayo dhiig ama candhuufta baaritaanka.

24 saacadood kaadi ah ayaa loo baahan yahay. Waxaad u baahan doontaa inaad kaadidaada ku soo ururiso in ka badan 24 saac weel ay shaybaadhku bixiso. Bixiyaha xanaanada caafimaadka ayaa kuu sheegi doona sida tan loo sameeyo. Raac tilmaamaha sida saxda ah.

Sababtoo ah soosaarka cortisol ee qanjirka 'adrenal gland' wuu kala duwanaan karaa, baaritaanka waxaa laga yaabaa inuu u baahdo in la sameeyo seddex ama in ka badan oo waqti gooni ah si loo helo sawir sax ah oo ku saabsan celceliska wax soo saarka cortisol.

Waxaa lagaa codsan karaa inaadan sameyn jimicsi xoog leh maalinta ka horreysa baaritaanka.

Waxaa sidoo kale laguu sheegi karaa inaad si ku meelgaar ah u joojiso qaadashada dawooyinka saamaynta ku yeelan kara baadhitaanka, oo ay ka mid yihiin:

• Daawooyinka ka-hortagga suuxdinta
• Estrogen
• Bini-aadamka lagu sameeyo (synthetic) glucocorticoids, sida hydrocortisone, prednisone iyo prednisolone
• Androgens

Baadhitaanku wuxuu ku lug leeyahay oo keliya kaadida caadiga ah. Ma jiraan wax dhib ah.

Tijaabada waxaa loo sameeyaa si loo hubiyo soosaarka cortisol ee kordhay ama u yaraaday. Cortisol waa hormoon glucocorticoid (steroid) ah oo laga sii daayo qanjirka 'adrenal gland' iyadoo laga jawaabayo hormoonka loo yaqaan 'adrenocorticotropic hormone' (ACTH). Kani waa hormoon laga sii daayo qanjirka 'pituitary gland' ee maskaxda. Cortisol wuxuu saameeyaa nidaamyo badan oo jidhka ah. Waxay door ka ciyaareysaa:

• Koritaanka lafaha
• Xakamaynta cadaadiska dhiigga
• Nidaamka difaaca jirka
• Dheef-shiid kiimikaadka dufanka, karbohaydraytyada, iyo borotiinka
• Shaqeynta nidaamka neerfaha
• Jawaabta cadaadiska

Cuduro kala duwan, sida Cushing syndrome iyo Addison disease, waxay u horseedi karaan wax soo saar aad u badan ama aad u yar oo ah cortisol. Qiyaasta heerka cortisol ee kaadida ayaa kaa caawin kara ogaanshaha xaaladahan.

Heerka caadiga ahi waa 4 illaa 40 mcg / 24 saac ama 11 illaa 110 nmol / maalin.

Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabin karaan tijaabooyin kala duwan. Kala hadal adeeg bixiyahaaga macnaha natiijooyinka baaritaankaaga gaarka ah.

Heer ka sareeya heerka caadiga ah ayaa tilmaami kara:

• Cudurka 'Cushing', oo qanjirka 'pituitary gland' uu aad uga badan yahay ACTH sababtoo ah koritaanka xad-dhaafka ah ee qanjirka 'pituitary gland' ama buro ku jirta qanjirka 'pituitary gland'
• Ectopic Cushing syndrome, kaas oo buro ka baxsan pituitary ama qanjidhada adrenal ay aad u badan ACTH
• Niyad jab daran
• Buro ka mid ah qanjidhada adrenal ee soosaarta cortisol aad u tiro badan
• Cadaadis daran
• Dhibaatooyin hidde ah oo dhif ah

Heer ka hooseeya heerka caadiga ah ayaa tilmaami kara:

• Cudurka 'Addison' kaas oo qanjidhada adrenal aysan soo saarin cortisol ku filan
• Hypopituitarism taas oo qanjirka 'pituitary gland' uusan u muujinayn qanjirka 'adrenal gland' inuu soo saaro cortisol ku filan
• Xakamaynta pituitary ama shaqada adrenal ee dawooyinka glucocorticoid oo ay ku jiraan kaniiniyada, kareemada maqaarka, indho fiiqista, neefsashada, irbadaha wadajirka ah, kemotherabi

Ma jiraan wax khatar ah oo ka imaan kara baaritaankaan.

24-saac cortisol lacag la'aan ah (UFC)

• Maqaarka kaadi mareenka
• Mareenka kaadi mareenka

Chernecky CC, Berger BJ. Cortisol - kaadi. Gudaha: Chernecky CC, Berger BJ, eds. Tijaabooyinka Shaybaarka iyo Nidaamyada Baadhista. 6aad ed. St Louis, MO: Elsevier Saunders; 2013: 389-390.

Stewart PM, Newell-Price JDC. Kiliyaha adrenal. Gudaha: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Buugga Buugga Endocrinology. 13aad. Philadelphia, PA: Elsevier; 2016: cutubka 15.