Qoraa: Gregory Harris
Taariikhda Abuurista: 12 Abriil 2021
Taariikhda Cusboonaysiinta: 18 Noofeembar 2024
Anonim
Amiodarone, Sotalol, and Dofetilide - Class III Antiarrhythmics Mechanism of Action and Side Effects
Dareemoleyad: Amiodarone, Sotalol, and Dofetilide - Class III Antiarrhythmics Mechanism of Action and Side Effects

Qanacsan

Dofetilide waxay sababi kartaa wadnahaaga inuu si aan caadi ahayn u garaaco. Waxaad ubaahantahay inaad kujirto isbitaal ama meel kale oo dhakhtarkaagu si dhaw ula socon karo uguyaraan 3 maalmood marka lagaa bilaabo ama dib loo bilaabo daawada loo yaqaan 'dofetilide'. Waxaa muhiim ah in la akhriyo macluumaadka bukaanka ee lagu siiyay markasta oo aad daawada ku bilowdo daawada loo yaqaan 'dofetilide'.

Dofetilide waxaa loo isticmaalaa in lagu daaweeyo garaaca wadnaha oo aan joogto ahayn (oo ay ku jiraan fibrillation-ka wadnaha) Waxay ku jirtaa nooc ka mid ah daawooyinka loo yaqaan 'antiarrhythmics'. Waxay hagaajineysaa laxanka wadnahaaga adigoo nasinaya qalbi kacsan.

Dofetilide waxay u timaadaa sidii kaabsol uu afka ku qaato. Badanaa waxaa la qaataa laba jeer maalintii, laakiin waxaa laga yaabaa in lagu qaado hal jeer maalintii dadka qaba xaaladaha qaarkood. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado dofetilide sida saxda ah ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

Dofetilide waxay maamushaa garaaca wadnaha aan caadiga ahayn laakiin ma daaweyso. Sii wad qaadashada dawada loo yaqaan 'dofetilide' xitaa haddii aad caafimaad qabtid. Ha u joojin daawada loo yaqaan 'dofetilide' adiga oo aan la hadlin dhakhtarkaaga.


Daawadan ayaa mararka qaarkood loo qoraa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada dawada loo yaqaan 'dofetilide',

  • u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay dawada 'dofetilide', dawooyin kale oo kasta, ama wax kasta oo ka kooban kaabsollada 'dofetilide'. Weydii farmashiistahaaga ama ka hubi macluumaadka bukaanka soo saaraha liiska waxyaabaha ay ka kooban yihiin.
  • u sheeg dhakhtarkaaga haddii aad qaadatid cimetidine (Tagamet), dolutegravir (Tivicay), hydrochlorothiazide (Microzide, Oretic), hydrochlorothiazide iyo triamterene (Dyazide, Maxzide), ketoconazole (Nizoral), megestrol (Megace), prochlorperazine trimethoprim (Primsol), trimethoprim iyo sulfamethoxazole (Bactrim, Septra, Sulfatrim), iyo verapamil (Calan, Covera, Verelan). Dhakhtarkaagu wuxuu kuu sheegi doonaa inaadan qaadan dawada 'dofetilide' haddii aad qaadanayso mid ama in kabadan oo dawooyinkan ah.
  • u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: amiloride (Midamor); antibiyootigyada sida erythromycin (E.E.S., E-Mycin) iyo norfloxacin (Noroxin); daawooyinka qaarkood ee fangaska sida fluconazole (Diflucan), itraconazole (Sporanox), iyo ketoconazole (Nizoral); bepridil (Vascor); cannabinoids sida dronabinol (Marinol), nabilone (Cesamet) ama marijuana (xashiish); digoxin (Lanoxin); diltiazem (Cardizem, Cartia XT, Dilacor XR, Taxtia XT, Tiazac); durayaasha ('kaniiniyada biyaha'); Ka hortagayaasha HIV protease oo ay ka mid yihiin atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), saquinavir (Invirase) iyo tipranavir (Apv); daawooyinka neefta sida zafirlukast (Accolate); daawooyinka niyadjabka, cudurka maskaxda, ama lallabbo; daawooyinka loogu talagalay garaaca wadnaha aan caadiga ahayn sida amiodarone (Cordarone, Pacerone); metformin (Fortamet, Glucophage, Glumetza, Riomet); nefazodone; ama quinine (Qualquin).
  • u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa qabtay QT syndrome (xaalad kordhinaysa halista ah inuu ku dhaco wadno garaac aan caadi ahayn oo u horseedi kara miyir beelid ama dhimasho lama filaan ah), ama cudur kelyo.
  • u sheeg dhakhtarkaaga haddii aad qabtid shuban xad-dhaaf ah, dhidid, matag, rabitaanka cuntada oo kaa yaraada, ama harraadku u yaraado ama heer-kaydka dhiigga ee dhiiggaaga ka hooseeyo, iyo haddii aad qabto ama aad waligaa qabtid cudur wadne ama beer.
  • u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanayso dawada loo yaqaan 'dofetilide', wac dhakhtarkaaga.

Kala hadal dhakhtarkaaga wax ku saabsan cunitaanka canab-gacmeedka ama cabitaanka casiir canab ah adoo qaadanaya daawada loo yaqaan 'dofetilide'.


Qaado qiyaasta la seegay isla marka aad xasuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaastaada xigta, ka bood qiyaasta la seegay oo sii wad jadwalkaaga qiyaasta daawada ee caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Dofetilide waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

  • madax xanuun
  • xabad xanuun
  • neefta oo ku qabata
  • lallabbo
  • astaamaha hargabka oo kale ah
  • calool xanuun
  • dhabar xanuun
  • dhibaato xagga hurdada ama hurdada ah

Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba wac dhakhtarkaaga:

  • dhakhso, garaacid, ama wadno garaac aan caadi ahayn
  • finan
  • shuban daran
  • wareer ama miyir beelid
  • dhidid aan caadi ahayn
  • matagid
  • cunto xumo
  • harraad kordhay (cabitaan ka badan inta caadiga ah)

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).


Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi heerkulka qolka oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha).

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Qiyaasta wadnahaaga waa in si joogto ah loo hubiyaa si loo ogaado jawaabtaada daawada loo yaqaan 'dofetilide'. Dhakhtarkaagu sidoo kale wuxuu rabaa inuu si dhow ula socdo shaqada kilyahaaga iyo heerka dhiigaaga ee kaalshiyamka ah intaad qaadanayso dofetilide.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

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