Fosamprenavir

Qanacsan

• Kahor qaadashada fosamprenavir,
• Fosamprenavir wuxuu sababi karaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac takhtarkaaga isla markiiba ama u hel daaweyn caafimaad oo deg-deg ah.

Fosamprenavir waxaa loo isticmaalaa dawooyin kale si loogu daaweeyo infekshanka fayraska difaaca jirka ee aadanaha (HIV). Fosamprenavir waxay kujirtaa nooc dawooyin ah oo loo yaqaan 'protease inhibitors'. Waxay ku shaqeysaa iyadoo la yareeyo qadarka HIV ee dhiiga ku jira.In kasta oo fosamprenavir uusan daaweynin HIV, waxay yareyn kartaa fursaddaada inaad kuhesho cudurada difaaca jirka (AIDS) iyo cudurada la xiriira HIV sida infekshanada halista ah ama kansarka. Qaadashada daawooyinkan oo ay weheliso ku-dhaqan galmo badbaado leh iyo is-beddello kale oo qaab nololeed ah ayaa yareyn kara halista gudbinta fayraska HIV ee dadka kale.

Fosamprenavir wuxuu u yimaadaa kiniin ahaan iyo ganaax (dareere) ah oo afka laga qaato. Waxaa badanaa la qaataa hal ama laba jeer maalintii. Kiniiniyada waa la qaadan karaa ama ha la cunin. Bukaannada ugu yaraan 18 sano jir, ka joojinta waa in lagu qaataa cunto la'aan. Bukaannada ka yar 18 sano jir, ka joojinta waa in lagu qaataa cunto. Si lagaaga caawiyo inaad xasuusato qaadashada fosamprenavir, qaado qiyaastii isku wakhti (iskuda) maalin kasta. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado fosamprenavir sida saxda ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

Haddii aad qaadatid ganaax, si fiican u rux kahor intaan la isticmaalin inaad isku darsato daawada si siman.

Haddii aad hunqaacdo wax ka yar 30 daqiiqo ka dib qaadashada fosamprenavir, waa inaad qaadataa qadar kale oo buuxa oo ah fosamprenavir.

Fosamprenavir wuxuu xakameeyaa infekshinka HIV laakiin ma daaweeyo. Sii wad inaad qaadato fosamprenavir xitaa haddii aad ladnaan dareento. Ha u joojin daawada fosamprenavir adiga oo aan la hadlin dhakhtarkaaga. Haddii aad seegto qiyaasaha ama aad joojiso qaadashada fosamprenavir, xaaladdaadu way sii adkaan doontaa in la daweeyo.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada fosamprenavir,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay fosamprenavir, amprenavir (Agenerase; oo aan hadda laga heli karin Maraykanka), dawooyinka sulfa, dawooyin kale, ama mid ka mid ah maaddooyinka ku jira kiniinnada fosamprenavir ama ganaax. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga haddii aad qaadanaysid alfuzosin (Uroxatral); cisapride (Propulsid) (aan laga heli karin Mareykanka); delavirdine (Qoraa); dawooyinka ergot sida dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergonovine, ergotamine (Ergomar, in Cafergot, in Migergot), iyo methylergonovine (Methergine); lomitapide (Juxtapid); lovastatin (Altoprev); midazolam (Aayaad); pimozide (Orap); rifampin (Rifadin, Rimactane, gudaha Rifater, Rifamate); sildenafil (kaliya magaca Revatio ee loo isticmaalo cudurka sanbabada); simvastatin (Zocor, oo ku yaal Vytorin); Johannesört wort; ama triazolam (Halcion). Dhakhtarkaagu wuxuu kuu sheegi doonaa inaadan qaadan fosamprenavir haddii aad qaadanayso mid ama in kabadan oo daawooyinkan ah.
• Ha u qaadin flecainide, lurasidone (Latuda), ama propafenone (Rhythmol) haddii aad wada qaadanaysid fosamprenavir iyo ritonavir (Norvir).
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinada, iyo nafaqada nafaqada aad qaadanaysid. Hubso inaad sheegto mid ka mid ah kuwan soo socda: daawooyinka xinjirowga lidka ku ah ('khafiifiyeyaasha dhiigga') sida warfarin (Coumadin, Jantoven); dawooyinka lidka diiqadda sida amitriptyline, imipramine (Surmontil), paroxetine (Brisdelle, Paxil, Pexeva), iyo trazodone; atorvastatin (Lipitor, Caduet); antacids ay ku jiraan aluminium iyo magnesium (Maalox, kuwa kale); benzodiazepines sida alprazolam (Xanax), clorazepate (Gen-Xene, Tranxene), diazepam (Diastat, Valium), iyo flurazepam; bosentan (Tracleer); kaalsiyamka xanibaada sida amlodipine (Norvasc, in Exforge, kuwa kale), diltiazem (Cardizem, Cartia, Tiazac, kuwa kale), felodipine, isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab CR, Procardia), nimodipine (Nymalize) nisoldipine (Sular), iyo verapamil (Calan, Covera, Verelan, Tarka); colchicine (Colcrys, Mitigare); dasatinib (Sprycel); dexamethasone; everolimus (Afinitor); fentanyl (Duragesic); fluticasone (Flonase, Flovent, Advair); xannibaadaha histamine H2-receptor sida cimetidine, famotidine (Pepcid), nizatidine (Axid), iyo ranitidine (Zantac); ibrutinib (Imbruvica); itraconazole (Onmel, Sporanox); daawooyinka loogu talagalay garaaca wadnaha oo aan joogto ahayn sida amiodarone (Nexterone, Pacerone), disspyramide (Norpace), lidocaine (Lidoderm; in Xylocaine with Epinephrine), iyo quinidine (in Nuedexta); ketoconazole (Nizoral); nilotinib (Tasigna); daawooyinka qalalaasaha sida carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, kuwa kale), phenobarbital, iyo phenytoin (Dilantin, Phenytek); daawooyinka xakameynaya nidaamka difaaca jirka sida cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), ama tacrolimus (Astagraf XL, Prograf); methadone (Dolophine, Methadose); dawooyin kale oo lagu daaweeyo HIV oo ay ka mid yihiin dolutegravir (Tivicay), efavirenz (Sustiva, in Atripla), indinavir (Crixivan), lopinavir (Kaletra), maraviroc (Selzentry), nelfinavir (Viracept), nevirapine (Viramune), raltegravir (Norvir, Kaletra, Viekira Pak), iyo saquinavir (Invirase); dawooyinka qaarkood si loo daaweeyo fayraska cagaarshowga C oo ay ku jiraan boceprevir (oo aan hadda laga helin Maraykanka; Victrelis), paritaprevir (Viekira XR), iyo simeprevir (oo aan hadda laga helin Maraykanka; Olysio); qaar ka mid ah fosfodiesterase inhibitors (PDE-5 inhibitors) oo loo isticmaalo cillad aan caadi ahayn sida sildenafil (Viagra), tadalafil (Cialis), iyo vardenafil (Levitra); quetiapine (Seroquel); rifabutin (Mycobutin); salmeterol (Serevent, Advair); tadalafil (Adcirca); iyo vinblastine. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca. Daawooyin kale oo badan ayaa sidoo kale la macaamili kara fosamprenavir, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan.
• u sheeg dhakhtarkaaga haddii aad qabtid ama waligaa aad qabtid sonkorow, hemophilia (cudur uusan dhiiggu si caadi ah u xinjiroobin), kolestarool sare ama triglycerides, ama kelyo ama beer xanuun, oo ay ku jiraan cagaarshowga B ama C.
• u sheeg dhakhtarkaaga haddii aad uur leedahay ama aad qorsheyneyso inaad uur yeelato. Haddii aad uur yeelato inta aad qaadanaysid fosamprenavir, wac dhakhtarkaaga. Waa inaadan naas nuujin haddii aad qabto cudurka HIV ama aad qaadato fosamprenavir.
• haddii aad qalliin samaynayso, oo ay ku jiraan qalliinka ilkaha, u sheeg dhakhtarka ama dhakhtarka ilkaha inaad qaadanayso fosamprenavir.
• waa inaad ogaataa in fosamprenavir ay yareyn karto waxtarka ka hortagga uurka ee afka (kaniiniyada xakameynta dhalmada). Kala hadal dhakhtarkaaga siyaabo kale oo looga hortago uurka inta aad qaadanaysid dawadan.
• waa inaad ogaataa in dufanka jirkaagu uu kordhi karo ama u dhaqaaqi karo meelo kala duwan oo jirkaaga ah sida naasahaaga iyo dhabarka kore.
• waa inaad ogaataa inaad la kulmi karto hyperglycemia (kordhinta sonkorta dhiiggaaga) inta aad qaadanaysid dawadan, xitaa haddii aadan horey u qabin cudurka macaanka. Isla markiiba u sheeg dhakhtarkaaga haddii aad isku aragto mid ka mid ah astaamaha soo socda inta aad qaadanaysid fosamprenavir: harraad aad u daran, kaadi badan, gaajo aad u daran, aragga oo xumaada, ama daciifnimo. Aad ayey muhiim u tahay inaad wacdid dhakhtarkaaga isla marka aad isku aragto mid ka mid ah astaamahan, maxaa yeelay sonkorta dhiigga ee sareysa ee aan la daaweyn waxay sababi kartaa xaalad halis ah oo loo yaqaan ketoacidosis. Ketoacidosis wuxuu noqon karaa mid nafta halis geliya haddii aan lagu daaweyn marxaladda hore. Calaamadaha lagu garto ketoacidosis waxaa ka mid ah: af qalalan, lallabbo iyo matag, neefta oo ku qabata, neefta oo urta miraha, iyo miyirka oo yaraada.
• Waa inaad ogaataa inta aad qaadanaysid dawooyinka lagu daaweynayo infekshinka HIV, nidaamkaaga difaaca ayaa laga yaabaa inuu sii xoogeysto oo uu bilaabo inuu la dagaallamo infekshannada kale ee horey ugu jiray jirkaaga. Tani waxay kugu sababi kartaa inaad yeelato calaamadaha infekshannadaas. Haddii aad leedahay calaamado cusub ama ka sii daraya wakhti kasta inta lagu jiro daweyntaada fosamprenavir, hubi inaad u sheegto dhakhtarkaaga.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Qaado qiyaasta la seegay isla marka aad xasuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaasta xigta, ka bood qiyaasta la seegay oo sii wad jadwalka daawadaada caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Fosamprenavir wuxuu sababi karaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• shuban
• lallabbo
• matagid
• madax xanuun
• daal xad dhaaf ah

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac takhtarkaaga isla markiiba ama u hel daaweyn caafimaad oo deg-deg ah.

• finan
• cuncun
• finan, nabarro, ama diirka maqaarka
• neefsashada ama wax liqidda oo ku adkaata
• barar wejigaaga, indhahaaga, bushimaha, carrabka, ama cunaha
• cuna xanuun, qandho, dhaxan, qufac, iyo calaamadaha kale ee infekshanka
• dhabar ama xanuun
• dhiig kaadida ku jira
• xanuun markaad kaadido

Fosamprenavir wuxuu sababi karaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi heerkulka qolka oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha). Hakinta ayaa sidoo kale lagu keydin karaa qaboojiyaha, laakiin ha barafaynin.

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu dalban karaa baaritaano shaybaar ah qaarkood kahor iyo inta daaweyntaadu socoto si loo hubiyo inay amaan kuugu tahay inaad qaadato fosamprenavir iyo inaad hubiso jawaabta jirkaaga ee fosamprenavir.

Dawadu ha kaa dhamaan. Marka saadkaaga fosamprenavir uu bilaabo inuu hooseeyo, wax badan ka hel dhakhtarkaaga ama farmashiistahaaga.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

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