Qoraa: Marcus Baldwin
Taariikhda Abuurista: 18 Juun 2021
Taariikhda Cusboonaysiinta: 16 Noofeembar 2024
Anonim
Posaconazole (Non Inferiority Trial) vs Voriconazole in Invasive Aspergillosis
Dareemoleyad: Posaconazole (Non Inferiority Trial) vs Voriconazole in Invasive Aspergillosis

Qanacsan

Kiniiniyada Posaconazole dib-u-sii-deynta iyo joojinta afka waxaa loo isticmaalaa in looga hortago infekshannada fangas ee daran ee ku dhaca dadka waaweyn iyo dhallinta 13-jirka ah iyo kuwa ka weyn oo leh awood daciif ah oo ay kula dagaallamaan infekshinka. Joojinta afka ee Posaconazole sidoo kale waxaa loo isticmaalaa in lagu daaweeyo caabuqa khamiirka ee afka iyo cunaha oo ay ku jiraan caabuqa khamiirka ee aan si guul leh loogu daaweyn karin daawooyinka kale. Posaconazole wuxuu ku jiraa nooc daawo ah oo loo yaqaan azole antifungals. Waxay ku shaqeysaa iyada oo hoos u dhigeysa koritaanka fangaska ee sababa infekshinka.

Posaconazole waxay u timaadaa sidii afka oo laga joojiyo (dareere) iyo dib-u-sii-dayn (waxay sii deysaa daawada xiidmaha si looga hortago in daawada ay ku jabto aashitada caloosha) kiniin afka laga qaato. Kiniinnada dib-u-sii-daayaha badanaa waxaa lagu qaataa cunto laba jeer maalintiiba maalinta koowaad ka dibna hal mar maalintii. Joojinta afka waxaa badanaa la qaataa seddex jeer maalintii iyadoo la qaato cunno buuxda ama 20 daqiiqo gudahood cuntada kadib. Haddii aadan qaadan karin ka hakinta afka cunno buuxda, ku qaado dheecaanka nafaqada ee dareeraha ah ama cabitaanka aashitada leh sida sinjibiil ale. Dhakhtarkaaga ayaa go'aamin doona inta aad u baahan tahay inaad isticmaasho daawadan. Qaado posaconazole qiyaastii isla waqtiyadiiba maalin kasta. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado posaconazole sida saxda ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.


Si fiican u rux joojinta afka si aad u isticmaasho ka hor intaan la istcimaalin.

Had iyo jeer isticmaal qaadada qiyaasta ee la socota joojinta afka ee posaconazole si aad u cabirto qiyaastaada. Waxaa laga yaabaa inaadan helin qadarka saxda ah ee daawada haddii aad u isticmaashid qaaddo reerka ah si aad u cabirto qiyaastaada. Qaadada waa in si fiican loogu mayriyaa biyo isticmaal kasta ka hor iyo ka hor inta aan la kaydin.

Liq kiniinka dib-u-sii-daayaha ee posaconazole oo dhan; ha kala qaybin, calalin, ama burburin. Haddii aadan wada liqi karin kiniinnada dib-u-dhigista dib-u-dhigga ah, u sheeg dhakhtarkaaga.

Wax soo saar kasta oo posaconazole ah ayaa sii daaya daawada si ka duwan jirkaaga loomana adeegsan karo.Kaliya qaado badeecada loo yaqaan 'posaconazole' oo uu dhakhtarkaagu kuu qoray oo ha u wareegin badeecad ka duwan tan posaconazole illaa dhakhtarkaagu kuu sheego mooyee.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.


Kahor qaadashada posaconazole,

  • u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad xasaasiyad ku leedahay posaconazole; daawooyinka kale ee antifungal sida fluconazole (Diflucan), isavuconazonium (Cresemba), itraconazole (Onmel, Sporanox), ketoconazole (Extina, Nizoral, Xolegel), ama voriconazole (Vfend); simethicone; daawooyin kale; ama mid ka mid ah maaddooyinka ku jira alaabada posaconazole. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
  • u sheeg dhakhtarkaaga haddii aad qaadato mid ka mid ah daawooyinka soo socda: atorvastatin (Lipitor, in Caduet), daawooyinka nooca ergot sida bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (DHE 45, Migranal), ergoloid mesylates (Hydergine), ergonovine , ergotamine (Ergomar, in Cafergot, in Migergot), iyo methylergonovine (Methergine); lovastatin (Altoprev, oo ku yaal Advicor); pimozide (Orap); quinidine (oo ku taal Nuedexta); simvastatin (Zocor, gudaha Simcor, Vytorin); ama sirolimus (Rapamune). Dhakhtarkaagu wuxuu kuu sheegi doonaa inaadan qaadan posaconazole haddii aad qaadanayso mid ama in kabadan oo daawooyinkan ah.
  • u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: benzodiazepines sida alprazolam (Xanax), diazepam (Valium), midazolam, iyo triazolam (Halcion); Kaalshiyamka kaaliyayaasha sida diltiazem (Cardizem, Cartia, Tiazac, kuwa kale), felodipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab CR, Procardia), iyo verapamil (Calan, Covera, Verelan, kuwa kale); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); efavirenz (Sustiva, oo ku taal Atripla); erythromycin (E.E.S., ERYC, Erythrocin, kuwa kale), fosamprenavir (Lexiva); glipizide (Glucotrol); phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); ritonavir (Norvir) oo lala qaatay atazanavir (Reyataz); tacrolimus (Astagraf, Envarsus XR, Prograf); vinblastine; iyo vincristine (Qalabka Marquibo). Haddii aad qaadanayso ganaax afka ah oo loo yaqaan posaconazole, sidoo kale u sheeg dhakhtarkaaga haddii aad qaadanayso cimetidine (Tagamet), esomeprazole (Nexium, in Vimovo), ama metoclopramide (Reglan). Daawooyin kale oo badan ayaa sidoo kale la macaamili kara posaconazole, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
  • u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa wadno garaac ama wadno-garaac aan caadi ahayn; waqti dheer oo QT ah (dhibaato wadno dhif ah oo sababi karta garaaca wadnaha oo aan joogto ahayn, suuxdin, ama dhimasho lama filaan ah); dhibaatooyinka wareegga dhiigga; heerarka hoose ee kaalshiyamka, magnesium, ama potassium ku jira dhiigaaga; ama kelyo, ama beer xanuun.
  • u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanaysid posaconazole, wac dhakhtarkaaga.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.


Haddii aad qaadanayso ka joojinta afka, qaado qiyaasta la seegay isla marka aad xusuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaasta xigta, ka bood qiyaasta la seegay oo sii wad jadwalka daawadaada caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Haddii aad qaadanaysid kiniinnada daahitaanka sii daayay, qaado qiyaasta la seegay isla marka aad xusuusatoba. Si kastaba ha noqotee, haddii ay tahay 12 saacadood gudahood qiyaastaada xigta, ka boodi qiyaasta la seegay oo sii wad jadwalkaaga qiyaasta daawada ee caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Posaconazole wuxuu sababi karaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

  • qandho
  • madax xanuun
  • qarqaryo ama gariirid
  • dawakhaad
  • daciifnimo
  • barar gacmaha, cagaha, anqawyada, ama lugaha hoose
  • shuban
  • matagid
  • calool xanuun
  • calool istaag
  • laabjeex
  • finan
  • cuncun
  • dhabar ama muruq xanuun
  • nabarrada bushimaha, afka, ama cunaha
  • dhibaato xagga hurdada ama hurdada ah
  • dhidid badan
  • sanka oo dhiig ka imanayo
  • qufac
  • cune xanuun

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta taxaddarrada qaaska ah, isla markiiba wac dhakhtarkaaga:

  • nabar ama dhiig bax aan caadi ahayn
  • daal xad dhaaf ah
  • tamar la’aan
  • cunto xumo
  • lallabbo
  • xanuun qeybta kore ee midig ee caloosha
  • hurdi maqaarka ama indhaha
  • astaamaha hargabka oo kale ah
  • kaadi madow
  • saxaro cirro leh
  • dhakhso, garaacid, ama wadno garaac aan caadi ahayn
  • miyir doorsoon
  • neefta oo ku qabata

Posaconazole wuxuu sababi karaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi heerkulka qolka oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha). Ha barafoobin joojinta afka.

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa tijaabooyinka shaybaarka qaarkood si loo hubiyo jawaabta jirkaaga ee posaconazole.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray. Haddii aad wali leedahay calaamadaha cudurka kadib markaad dhameysato qaadashada posaconazole, wac dhakhtarkaaga.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

  • Noxafil®
Markii ugu dambeysay ee dib loo eegay - 04/15/2016

Maanta Xiiso Leh

14 Waxyaabaha Ay Haweenka 50 Jirkooda Ku Sheegayaan Inay Si Kala Duwan U Qaban Doonaan

14 Waxyaabaha Ay Haweenka 50 Jirkooda Ku Sheegayaan Inay Si Kala Duwan U Qaban Doonaan

Markii aad ii gabowdaba, waxaad aragti ka helay aa muraayadda muraayadda nolo haada.Waa maxay waxa ku aab an gabowga ee dumarka ka farxiya markay ii weynaadaan, gaar ahaan inta u dhexey a 50 ilaa 70 j...
Daawada Guriga ee Diverticulitis Ma U Noqon Kartaa Jawaabta Xanuunkaaga Caloosha?

Daawada Guriga ee Diverticulitis Ma U Noqon Kartaa Jawaabta Xanuunkaaga Caloosha?

Waxaan ku darnaa badeecooyin aan u maleyneyno inay faa'iido u leeyihiin akhri tayaa hayada. Haddii aad wax kaga iib ato xiriiriyeyaa ha ku yaal boggan, waxaa laga yaabaa inaan ka bano komi han yar...