Dextromethorphan iyo Quinidine
Qanacsan
- Kahor qaadashada dextromethorphan iyo quinidine,
- Isku darka dextromethorphan iyo quinidine waxay sababi karaan waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
- Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac dhakhtarkaaga isla markiiba:
- Calaamadaha xad dhaafka ah waxaa ka mid noqon kara:
Isku darka dextromethorphan iyo quinidine waxaa loo isticmaalaa in lagu daaweeyo saameynta 'pseudobulbar' (PBA; xaalad kadis ah, qulqulka joogtada ah ee oohinta ama qosolka aan la xakamayn karin) dadka qaba xaaladaha qaarkood sida amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease; condition) taas oo dareemayaasha xakameynaya dhaqdhaqaaqa muruqyada ay si tartiib ah u dhintaan, taasoo keeneysa murqaha inay yaraadaan oo daciifaan) ama sclerosis (cudur aan dareemayaasha si sax ah u shaqeynin oo bukaanku la kulmi karo daciifnimo, kabuubyo, luminta isuduwidda muruqyada iyo dhibaatooyinka aragtida, hadalka, iyo kontoroolka kaadiheysta). Dextromethorphan wuxuu ku jiraa fasal dawooyin ah oo loo yaqaan wakiilada nidaamka neerfaha. Qaabka ay uga shaqeyso maskaxda si loo daaweeyo PBA lama yaqaan. Quinidine waxay ku jirtaa nooc daawooyin ah oo loo yaqaan 'antiarrhythmics'. Marka lagu daro dextromethorphan, quinidine wuxuu shaqeeyaa iyadoo la kordhinayo xaddiga dextromethorphan ee jirka.
Isku darka dextromethorphan iyo quinidine wuxuu u yimaadaa kaabsol si afka looga qaato. Waxaa badanaa la qaataa ama cunno la'aan maalintii hal mar muddo 7 maalmood ah. 7 maalmood kadib, waxaa laqaadayaa 12kii saacadoodba mar. Ha qaadan wax ka badan 2 qaadasho muddo 24-saac ah. Hubso inaad u oggolaato qiyaastii 12 saacadood inta u dhexeysa qiyaas kasta. Qaado dextromethorphan iyo quinidine isla waqtigaas (iskuda) maalin kasta. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado isku darka dextromethorphan iyo quinidine sida saxda ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.
Dhakhtarkaaga ayaa laga yaabaa inuu hubiyo waqti ka waqti inuu arko in daawadan wali loo baahan yahay si loo xakameeyo astaamahaaga. Raac tilmaamahan si taxaddar leh.
Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.
Kahor qaadashada dextromethorphan iyo quinidine,
- u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay dextromethorphan, quinidine (Quinidex), quinine (Qualaquin), mefloquine (Lariam), dawooyin kale oo kasta, ama mid ka mid ah maaddooyinka isku jira dextromethorphan iyo quinidine capsules. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
- u sheeg dhakhtarkaaga haddii aad qaadanaysid mefloquine (Lariam), pimozide (Orap), quinine (Qualaquin) thioridazine, ama shey kale oo ka kooban quinidine (Quinidex). Dhakhtarkaaga ayaa u badan inuu kuu sheego inaadan qaadan dextromethorphan iyo quinidine haddii aad qaadanayso mid ama kabadan dawooyinkan.
- u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: daawada niyadjabka oo ay ka mid yihiin clomipramine (Anafranil), desipramine (Doxepin, Sinequan), fluoxetine (Prozac, Sarafem), nefazodone, iyo paroxetine (Paxil, Pexeva); danaysane (Emend); clarithromycin (Biaxin, Prevpac); qufaca iyo dawooyinka qabow ee ka kooban dextromethorphan; burburin; digoxin (Lanoxin, Digitek); erythromycin (EE.S E-Mycin, Erythrocin); fluconazole (Diflucan); itraconazole (Sporanox); ketoconazole (Nizoral); dawooyinka qaarkood ee fayraska difaaca jirka (HIV) sida atazanavir (Reyataz), amprenavir (Agenerase), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), iyo saquinavir (Invse); daawooyinka wadna garaaca wadnaha aan joogtada ahayn sida amiodarone (Cordarone), diltiazem (Cardizem, Cartia, Tiazac, kuwa kale), disspyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid, Pronestyl), sotalol (Betapace), iyo verapamil (Calan, Covera, Isoptin, Verelan, oo ku taal Tarka); daawooyinka xanuunka sida kodein, hydrocodone (in Hydrogesic, Lorcet, Lortab, Vicodin, Zydone, kuwa kale), iyo methadone; moxifloxacin (Avelox); sparfloxacin (Zagam); iyo teliththromycin (Ketek). Sidoo kale u sheeg dhakhtarkaaga ama farmashiistaha haddii aad qaadanaysid daawooyinka soo socda ama aad joojisay qaadashadooda labadii toddobaad ee la soo dhaafay: MAO inhibitors ay ka mid yihiin isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl ), iyo tranylcypromine (Parnate). Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca. Daawooyin kale oo badan ayaa sidoo kale la macaamili kara dextromethorphan iyo quinidine, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan.
- u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa soo martay xaaladaha soo socda inta aad qaadanaysid quinidine, quinine, ama mefloquine: hoos u dhaca tirada unugyada dhiigga ee dhuuxa laftaada, lupus (xaalad jirku ku weeraro unugyadiisa u gaarka ah oo keena dhaawac iyo barar ), ama cagaarshow (beerka oo barara). Sidoo kale u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa yeelatay habdhac aan caadi ahayn oo wadnaha ah ama wadno qabad la'aan. Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaadan qaadan takedextromethorphan iyo quinidine.
- u sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa qabtid cudurka 'myasthenia gravis' (cillad ku dhacda habdhiska neerfaha ee sababa murqaha oo daciif noqda), taariikhda isticmaalka daroogada dariiqa ama isticmaalka daawada ee loo isticmaalo si khaldan, dhiig karka, istaroog, heerarka hoose ee potassium ama magnesium in dhiigaaga, ama wadnaha, kilyaha, ama cudurka beerka.
- u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelatid inta aad qaadanaysid isku darka dextromethorphan iyo quinidine, wac dhakhtarkaaga.
- haddii aad qalliin samaynayso, oo ay ku jiraan qalliinka ilkaha, u sheeg dhakhtarka ama dhakhtarka ilkaha inaad qaadanayso dextromethorphan iyo quinidine.
- waa inaad ogaataa in dextromethorphan iyo quinidine ay dawakhaad kugu ridi karaan. Waxaa muhiim ah in laga taxadiro in laga fogaado dhicitaanka inta aad qaadaneyso daawadan.
- Weydii dhakhtarkaaga isticmaalka aaminka ah ee cabitaanka khamriga ah inta aad qaadanayso dextromethorphan iyo quinidine. Aalkoladu waxay ka dhigi kartaa waxyeelada dawadan.
Kala hadal dhakhtarkaaga wax ku saabsan cunitaanka canab-gacmeedka iyo cabitaanka casiir canab ah adoo qaadanaya dawadan.
Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.
Ka gudub xaddiga aad seegtay oo qaado qiyaasta xigta waqtiga caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay. Hubso inaad u oggolaato 12 saacadood inta u dhexeysa qiyaasaha.
Isku darka dextromethorphan iyo quinidine waxay sababi karaan waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
- shuban
- matagid
- gaaska
- calool xanuun
- qufac
- indhaha qallalan ama afka
- daciifnimo
- murqo xanuun
- barar gacmaha, cagaha, anqawyada, ama lugaha hoose
- kaadi badan, xanuun badan, ama dhib badan
- kaadi daruur ama ur xoog leh leh
Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac dhakhtarkaaga isla markiiba:
- qandho
- dhiigbax ama nabar aan caadi ahayn
- murqaha ama kalagoysyada oo xanuuna
- finan
- barar wejiga, cunaha, carrabka, ama dibnaha
- qanjidhada oo barara
- xabeeb
- neefsashada oo adkaata
- madax wareer
- miyir beelid
- wadnaha garaacid
Isku darka dextromethorphan iyo quinidine waxay sababi karaan waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.
Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).
Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan gaari karin carruurta iyo xayawaanku. Ku keydi heerkulka qolka oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha).
Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.
Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org
Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.
Calaamadaha xad dhaafka ah waxaa ka mid noqon kara:
- lallabbo
- matagid
- shuban
- dawakhaad
- madax xanuun
- dhagaha ka yeeraya
- aragga oo xumaada ama labalaabma
- jahwareer
- isbeddelka garaaca wadnaha
- neefsashada oo adkaata
- miyir beelid
- qalal
- isbeddelada fal-celinta murqaha
- luminta isuduwidda
- farxad aan caadi ahayn
- fikir aan caadi ahayn
Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu dalban karaa tijaabooyin shaybaarro qaarkood ah si loo hubiyo jawaabta jirkaaga ee dextromethorphan iyo quinidine. Dhakhtarkaagu wuxuu kaloo amri karaa electrocardiogram-ka (ECG; baaritaanka cabiraya dhaqdhaqaaqa korantada ee wadnaha) kahor iyo inta lagaa daaweynayo.
Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.
Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.
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