Efavirenz, Emtricitabine, iyo Tenofovir

Qanacsan

• Kahor intaadan qaadan efavirenz, emtricitabine, iyo tenofovir,
• Efavirenz, emtricitabine, iyo tenofovir waxay sababi karaan waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:
• Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

Efavirenz, emtricitabine, iyo tenofovir waa in aan loo isticmaalin in lagu daaweeyo infekshinka fayraska cagaarshow B (HBV, infekshinka beerka ee socda) U sheeg dhakhtarkaaga haddii aad qabtid ama aad u malaynaysid inaad leedahay cudurka HBV. Dhakhtarkaaga ayaa laga yaabaa inuu ku tijaabiyo inuu arko haddii aad qabto HBV ka hor intaadan bilaabin daaweyntaada efavirenz, emtricitabine, iyo tenofovir. Haddii aad HBV leedahay oo aad qaadato efavirenz, emtricitabine, iyo tenofovir, xaaladaadu si lama filaan ah ayey uga sii dari kartaa marka aad joojiso qaadashada daawadan. Dhakhtarkaaga ayaa ku baari doona kuna amri doona baaritaano shaybaar si joogto ah dhowr bilood ka dib markaad joojiso qaadashada daawadan si loo arko in HBV-gaagu ka sii daray

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa baaritaano gaar ah kahor iyo inta daaweyntaadu socoto si loo hubiyo jawaabta jirkaaga ee efavirenz, emtricitabine, iyo tenofovir.

Kala hadal dhakhtarkaaga khataraha qaadashada efavirenz, emtricitabine, iyo tenofovir.

Isku darka efavirenz, emtricitabine, iyo tenofovir ayaa loo isticmaalaa kali ama daawooyin kale si loogu daaweeyo infekshanka difaaca jirka ee aadanaha (HIV) ee dadka waaweyn iyo caruurta culeyskoodu ka badan yahay 40 kg (88 lb). Efavirenz waxay ku jirtaa nooc daawooyin ah oo aan ahayn nukleoside transcriptase inhibitors (NNRTIs). Emtricitabine iyo tenofovir waxay ku jiraan nooc daawooyin ah oo loo yaqaan 'nucleoside reverse transcriptase inhibitors' (NRTIs). Waxay ku shaqeeyaan iyaga oo yareeya qadarka HIV ee jirka ku jira. In kasta oo efavirenz, emtricitabine, iyo tenofovir ayna bogsiin doonin HIV, haddana daawooyinkani waxay yareyn karaan fursaddaada aad kuheleyso cudurka difaaca jirka ee aad heshay (AIDS) iyo cudurada la xiriira HIV sida infekshannada halista ah ama kansarka. Qaadashada daawooyinkan oo ay weheliso ku-dhaqan galmo badbaado leh iyo isbeddello kale oo hab-nololeed ah ayaa yareyn kara halista qaadista ama u gudbinta fayraska HIV dadka kale.

Isku darka efavirenz, emtricitabine, iyo tenofovir waxay u yimaadaan sidii kiniin afka lagu qaato. Badanaa waxaa la qaataa maalintii hal mar biyo calool madhan (ugu yaraan 1 saac kahor ama 2 saac cuntada kadib). Qaado efavirenz, emtricitabine, iyo tenofovir waqti isku mid ah maalin kasta. Qaadashada efavirenz emtricitabine, iyo tenofovir wakhtiga jiifka waxay ka dhigi kartaa waxyeelooyinka qaarkood kuwo aan dhib badneyn. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado efavirenz, emtricitabine, iyo tenofovir sida saxda ee lagugu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

Sii wad inaad qaadato efavirenz, emtricitabine, iyo tenofovir xitaa haddii aad ladnaan dareento. Ha u joojin qaadashada efavirenz, emtricitabine, iyo tenofovir adigoon dhaqtarkaaga la hadlin. Haddii aad joojiso qaadashada efavirenz, emtricitabine, iyo tenofovir xitaa waqti gaaban, ama ka bood qiyaaso, fayrasku wuxuu u adkaysan karaa daawooyinka waana laga yaabaa inuu adkaado in la daweeyo.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan qaadan efavirenz, emtricitabine, iyo tenofovir,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay efavirenz, emtricitabine, ama tenofovir, daawooyin kale, ama mid ka mid ah waxyaabaha ku jira efavirenz, emtricitabine, iyo kiniiniyada tenofovir. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga haddii aad qaadanayso voriconazole (Vfend) ama elbasvir iyo grazoprevir (Zepatier). Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaadan qaadan efavirenz, emtricitabine, iyo tenofovir haddii aad qaadanaysid mid ama kabadan dawooyinkan.
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, ee aad qaadaneyso ama aad qorsheyneyso inaad qaadato Hubso inaad sheegto mid ka mid ah kuwan soo socda: acyclovir (Sitavig, Zovirax); adefovir (Hepsera); dawooyinka lidka diiqadda; farshaxanka iyo lumefantrine (Coartem); atazanavir (Reyataz); atorvastatin (Lipitor, Caduet); atovaquone iyo proguanil (Malarone); boceprevir (Victrelis); bupropion (Wellbutrin, Zyban, kuwa kale); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); clarithromycin (Biaxin, gudaha Prevpac); cidofovir; cyclosporine (Gengraf, Neoral, Sandimmune); darunavir (Prezista) oo leh ritonavir (Norvir); delavirdine (Qoraa); didanosine (Videx); diltiazem (Cardizem, Cartia, Diltzac, Taztia, Tiazac); ethinyl estradiol iyo norgestimate (Estarylla, Ortho-Tri-Cyclen, Sprintec, kuwa kale); etonogestrel (Nexplanon, oo ku yaal Nuvaring); etravirine (Intelence); felodipine; fosamprenavir (Lexiva); ganciclovir (Cytovene); gentamicin; glecaprevir iyo pibrentasvir (Mavyret); indinavir (Crixivan); itraconazole (Onmel, Sporanox); ketoconazole; lamivudine (Epivir, Epivir HBV, oo ku yaal Combivir, Epzicom, Triumeq, Trizivir); ledipasvir iyo sofosbuvir (Harvoni); lopinavir iyo ritonavir (Kaletra); maraviroc (Selzentry); daawooyinka walwalka, cudurka maskaxda, iyo qalalka; methadone (Dolophine, Methadose); nevirapine (Viramune); nicardipine (Cardene); nifedipine (Adalat, Afeditab, Procardia); phenobarbital; phenytoin (Dilantin, Phenytek); daawooyinka nonsteroidal anti-inflammatory (NSAIDs) sida selecoxib (Celebrex), ibuprofen (Advil, Motrin), meloxicam (Mobic), iyo naproxen (Aleve, Naprelan, Naprosyn); daawooyinka kale ee HIV ee ay kujiraan efavirenz, emtricitabine, iyo tenofovir (Complera, Descovy, Genvoya, Odefsey, Stribild, Truvada, Sustiva, Emtriva, Viread); posaconazole (Noxafil); pravastatin (Pravachol); raltegravir (Isentress); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, gudaha Rifamate, Rifater); ritonavir (Norvir, Kaletra, Technivie, Viekira Pak); saquinavir (Invirase); dajiya; sertraline (Zoloft); kaniiniyada hurdada; simeprevir (Olysio); simvastatin (Zocor, oo ku yaal Vytorin); sirolimus (Rapamune); sofosbuvir iyo velpatasvir (Epclusa); sofosbuvir, velpatasvir, iyo voxilaprevir (Vosevi); tacrolimus (Astagraf, Envarsus, Prograf); dejiyeyaasha; valacyclovir (Valtrex); valganciclovir (Valcyte); verapamil (Calan, Covera, Tarka, Verelan); iyo warfarin (Coumadin, Jantoven). Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca. Daawooyin kale oo badan ayaa sidoo kale la macaamili kara efavirenz, emtricitabine, iyo tenofovir, ama waxay kordhin karaan halista aad ku yeelan karto dhaawaca beerka inta lagu jiro daaweyntaada efavirenz, emtricitabine, iyo tenofovir, marka hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid , xitaa kuwa aan ka muuqan liiskan.
• u sheeg dhakhtarkaaga waxa ka soo baxa dhirta aad qaadanaysid, gaar ahaan johannesört wort.
• u sheeg dhakhtarkaaga haddii aad hadda ama aad leedahay waqti dheer oo QT ah (dhibaato wadnaha oo dhif ah oo sababi karta garaaca wadnaha oo aan joogto ahayn, suuxdin, ama dhimasho lama filaan ah), ama heerarka hoose ee potassium ama magnesium ee dhiiggaaga, weligaa cabbo qamri aad u tiro badan, daroogooyinka waddooyinka la isticmaalay , ama daawooyinka loo qoro ee aad loo isticmaalay. Sidoo kale u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa yeelatay mid ka mid ah xaaladaha lagu xusay qaybta DIGNIINTA MUHIIMKA ah, niyad-jabka ama cudurro kale oo maskaxeed, dhibaatooyinka lafaha oo ay ka mid yihiin lafo-beelka (xaalad ah in lafuhu noqdaan kuwo khafiif ah oo daciif ah oo si fudud u jajabaya) ama jabka lafta , qalal, ama cudur beerka ama kalyaha ah.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, ama qorsheyso inaad uur yeelato.Waa inaadan uur yeelan inta aad daweyneyso iyo 12 toddobaad ka dib qiyaastaada ugu dambeysa. Haddii aad uur qaadi karto, waa inaad maraysaa baaritaanka uurka ee xun ka hor intaadan bilaabin qaadashada daawadan oo aad u isticmaasho xakameynta uurka ee waxtarka leh inta lagu jiro daaweyntaada. Efavirenz, emtricitabine, iyo tenofovir ayaa laga yaabaa inay farageliyaan ficilada ka hortagga uurka ee hormoonnada (kaniiniyada xakamaynta dhalmada, balastarro, faraantiyo, irbado, ama irbado), marka waa inaadan u isticmaalin kuwan habka kaliya ee aad ku xakameyn karto uurka inta aad daweyneyso. Waa inaad isticmaashaa habka ka hortagga uurka ee xakameynta (aaladda xanibaysa manida galaya ilmo galeenka sida cinjirka galmada ama cinjirka 'diaphragm') oo ay weheliso qaab kasta oo kale oo xakameynta dhalmada ah oo aad dooratay. Weydiiso dhakhtarkaaga inuu kaa caawiyo xulashada habka xakameynta dhalmada ee adiga kuu shaqeyn doonta. Haddii aad uur yeelato inta aad qaadanaysid efavirenz, emtricitabine, iyo tenofovir, isla markiiba wac dhakhtarkaaga.
• waa inaadan naas nuujin haddii aad qabtid cudurka HIV ama aad qaadatid efavirenz, emtricitabine, iyo tenofovir.
• waa inaad ka warqabtaa in dufanka jirkaagu uu kordhin karo ama u dhaqaaqi karo meelo kala duwan oo jirkaaga ka mid ah, sida dhabarka kore, qoorta ('' buffalo hump ''), naasaha, iyo calooshaada ku wareegsan. Waxaad dareemi kartaa luminta dufanka jirka ee wajiga, lugaha, iyo gacmaha.
• Waa inaad ogaataa inta aad qaadanaysid dawooyinka lagu daaweynayo infekshinka HIV, nidaamkaaga difaaca ayaa laga yaabaa inuu sii xoogeysto oo uu bilaabo inuu la dagaallamo infekshannada kale ee horay ugu jiray jirkaaga ama u sababi kara xaalado kale inay dhacaan. Tani waxay kugu sababi kartaa inaad yeelato calaamadaha cuduradaas ama xaaladahaas. Haddii aad leedahay calaamado cusub ama ka sii daraya inta lagu jiro daweyntaada efavirenz, emtricitabine, iyo tenofovir hubi inaad u sheegto dhakhtarkaaga.
• waa inaad ogaataa in efavirenz, emtricitabine, iyo tenofovir ay kaa dhigi karaan lulmo, wareer, ama awoodin inaad feejignaato. Gaari ha wadin ama ha ku shaqeynin mishiin ilaa aad ka ogaato sida daawadani kuu saameyneyso.
• waa inaad ogaataa in efavirenz, emtricitabine, iyo tenofovir ay sababi karaan isbadal fikirkaaga, dhaqankaaga, ama caafimaadka maskaxdaada. Wac dhakhtarkaaga isla markiiba haddii aad isku aragto mid ka mid ah astaamaha soo socda inta aad qaadanaysid efavirenz: diiqad, ka fikirida naftaada inaad is disho ama aad qorsheyso ama aad isku daydo inaad sidaas sameyso, caro ama dabeecad dagaal leh, dhalanteed (aragtida wax ama maqalka codad aan jirin) fikradaha qalaad, ama luminta taabashada xaqiiqda. Hubso in qoyskaagu ogyahay astaamaha halista ah si ay ugu wici karaan dhakhtarkaaga haddii aadan awoodin inaad keligaa daaweyn raadsato.
• weydii dhakhtarkaaga wax ku saabsan isticmaalka aaminka ah ee cabitaanka khamriga ah inta aad qaadaneysid efavirenz, emtricitabine, iyo tenofovir. Aalkoladu waxay ka sii dari kartaa dhibaatooyinka soo raaca efavirenz, emtricitabine, iyo tenofovir.
• waa inaad ogaataa in efavirenz uu sababi karo dhibaatooyin xagga nidaamka neerfayaasha ah oo halis ah, oo ay kujiraan encephalopathy (xanuun daran oo suuragal ah inuu u dhinto maskaxda) bilo ama sannado kadib marka ugu horeysa ee aad qaadatid efavirenz, emtricitabine, iyo tenofovir. Inkasta oo dhibaatooyinka nidaamka neerfaha ay bilaaban karaan kadib markaad qaadatay efavirenz, emtricitabine, iyo tenofovir in mudo ah, waa muhiim adiga iyo dhakhtarkaaga inaad ogaato inay sababi karaan efavirenz. Wac dhakhtarkaaga isla markiiba haddii aad la kulanto dhibaatooyin isku dheelitirnaan iyo iskuduwid ah, jahwareer, dhibaatooyinka xusuusta, iyo dhibaatooyin kale oo ka dhasha shaqada maskaxda ee aan caadiga ahayn, wakhti kasta inta lagu jiro daaweyntaada efavirenz, emtricitabine, iyo tenofovir. Dhakhtarkaagu wuxuu kuu sheegi karaa inaad joojiso qaadashada efavirenz, emtricitabine, iyo tenofovir.

Kala hadal dhakhtarkaaga wax ku saabsan cunitaanka canab-gacmeedka iyo cabitaanka casiir canab ah adoo qaadanaya dawadan.

Qaado qiyaasta la seegay isla marka aad xasuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaasta xigta, ka bood qiyaasta la seegay oo sii wad jadwalka daawadaada caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Efavirenz, emtricitabine, iyo tenofovir waxay sababi karaan waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• madax xanuun
• shuban
• gaaska
• dheef-shiid
• midabka maqaarka oo madoobaada, gaar ahaan calaacasha gacmaha ama cagaha
• maqaarka cirro leh
• dhibaato xagga hurdada ama hurdada ah
• jahwareer
• hilmaamid
• dareemid kacsan, walwal, ama walwal
• niyadda aan caadiga ahayn ee faraxsan
• riyooyin aan caadi ahayn
• kala-goysyada ama dhabarka
• cuncun

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:

• kaadida oo yaraatay
• kaadi badan
• harraad u kordhay
• lafo xanuun socda ama ka sii daraya
• jabka lafaha
• xanuun ku dhaca gacmaha, gacmaha, cagaha, ama lugaha
• murqo xanuun ama daciifnimo
• finan
• xoqidda, finka, ama daadinta maqaarka
• kabuubyo, gubasho, ama xoqid gacmaha, gacmaha, cagaha, ama lugaha
• barar wejiga, cunaha, carrabka, bushimaha, indhaha, lugaha, anqawyada, ama cagaha
• dhib liqidda ama neefsashada
• xabeeb
• qalal
• astaamaha hargabka oo kale ah
• lallabbo
• matagid
• daal xad dhaaf ah
• hurdi maqaarka ama indhaha; saxaro midab khafiif ah leh; kaadi kaadi huruud ah ama bunni ah; cunto xumo; xanuun qaybta sare ee midig ee caloosha; ama dhiig bax aan caadi ahayn ama nabar
• daciifnimo; muruq xanuun; neefta oo ku qabata ama neefsashada oo deg deg ah; calool xanuun lallabbo iyo matag; gacmaha iyo cagaha qabow ama buluug ah; madax wareer ama madax wareer; ama garaaca wadnaha oo degdeg ah ama aan caadi ahayn

Efavirenz, emtricitabine, iyo tenofovir waxay sababi karaan waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi heerkulka qolka oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha).

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

• dhaqdhaqaaqa jirkaaga oo aadan xakamayn karin
• dawakhaad
• adkaanshaha feejignaanta
• gariirid
• jahwareer
• hilmaamid
• dhibaato xagga hurdada ama hurdada ah
• riyooyin aan caadi ahayn
• lulmid
• dhalanteed (aragtida wax ama maqalka codad aan jirin)
• niyadda aan caadiga ahayn ee faraxsan
• fikrado yaab leh

Kahor baaritaanka sheybaarka, u sheeg dhakhtarkaaga iyo shaqaalaha sheybaarka inaad qaadanayso efavirenz, emtricitabine, iyo tenofovir.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Ku hayso sahayda efavirenz, emtricitabine, iyo tenofovir gacanta. Ha sugin illaa ay kaa dhammaato daawada si aad ugu buuxiso dawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Atripla^® (sida shey isku dhafan oo ka kooban Efavirenz, Emtricitabine, Tenofovir)