Cirbadda Phenytoin

Qanacsan

• Kahor intaadan qaadan cirbadeynta fenytoin,
• Phenytoin wuxuu sababi karaa koror ku yimaada sonkorta dhiigaaga. Kala hadal dhakhtarkaaga calaamadaha sonkorta dhiigga oo sarreeya iyo waxa la sameeyo haddii aad calaamadahaas isku aragto.
• Cirbadda Phenytoin waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamaha soo socda ama kuwa ku taxan qaybta taxaddarrada qaaska ah, isla markiiba wac dhakhtarkaaga:
• Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

Waxaad la kulmi kartaa cadaadis dhiig oo hooseeya oo halis ah ama nafta halis geliya ama garaaca wadnaha oo aan joogto ahayn inta aad qaadanayso cirbadda fenytoin ama ka dib. U sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa yeelatay wadna garaac aan caadi ahayn ama wadne xannibaad (xaalad aan calaamadaha korantada si caadi ah looga gudbin qolalka sare ee wadnaha loona aadin qolalka hoose). Dhakhtarkaaga ayaa laga yaabaa inuusan rabin inaad hesho cirbadda fenyyotiin. Sidoo kale, u sheeg dhakhtarkaaga haddii aad qabtid ama aad waligaa wadnaha istaagtay ama dhiig kar hooseeyo. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba u sheeg dhakhtarkaaga: dawakhaad, daal, garaaca wadnaha oo aan joogto ahayn, ama laab xanuun.

Waxaad kuheli doontaa qadar kasto oo ah cirbada fenytoin ee xarunta caafimaadka, takhtar ama kalkaaliye caafimaad ayaa kula socon doona si taxaddar leh inta aad qaadaneyso daawada iyo kadib

Cirbadda Phenytoin waxaa loo isticmaalaa in lagu daaweeyo suuxdinta guud ee guud ee loo yaqaan 'tonic-clonic suiziz' (oo horay loogu yaqaanay suuxdin weyn, suuxdin ku lug leh jirka oo dhan) iyo in lagu daaweeyo lagana hortago qalalka oo bilaaban kara inta lagu jiro ama ka dib qalliinka maskaxda ama nidaamka dareenka. Cirbadda Phenytoin ayaa sidoo kale loo isticmaali karaa in lagu xakameeyo noocyada suuxdinta ee dadka aan qaadan karin fenytoin afka ah. Phenytoin wuxuu ku jiraa fasal dawooyin ah oo loo yaqaan 'anticonvulsants'. Waxay ku shaqeysaa iyadoo hoos loo dhigo dhaqdhaqaaqa korantada ee aan caadiga ahayn ee maskaxda.

Cirbadda Phenytoin waxay u timaaddaa xalka (dareeraha) in si tartiib ah loogu mudo irbadda (xididka) dhakhtar ama kalkaaliye caafimaad oo jooga goob caafimaad. Badanaa waxaa la isku duraa 6dii ama 8dii saacadoodba mar.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Cirbadda Phenytoin ayaa sidoo kale loo isticmaalaa in lagu xakameeyo garaaca wadnaha oo aan joogto ahayn. Kala hadal dhakhtarkaaga khataraha aad u leedahay isticmaalka dawadan xaaladaada.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan qaadan cirbadeynta fenytoin,

• u sheeg dhakhtarkaaga iyo farmasiilahaaga haddii aad xasaasiyad ku leedahay phenytoin, daawooyinka kale ee hydantoin sida ethotoin (Peganone) ama fosphenytoin (Cerebyx), daawooyin kale oo kasta, ama wax kasta oo ka mid ah waxyaabaha ku jira cirbadda phenytoin. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga haddii aad qaadanaysid delavirdine (Rescriptor). Dhakhtarkaaga ayaa laga yaabaa inuusan rabin inaad hesho cirbadeynta phenytoin haddii aad qaadanaysid dawadan.
• u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: albendazole (Albenza); amiodarone (Nexterone, Pacerone); daawooyinka xinjirowga lidka ku ah ('khafiifiyeyaasha dhiigga') sida warfarin (Coumadin, Jantoven); daawooyinka fangaska sida fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Onmel, Sporanox, Tolsura), miconazole (Oravig), posaconazole (Noxafil), iyo voriconazole (Vfend); fayrasyada qaarkood sida efavirenz (Sustiva, Atripla), indinavir (Crixivan), lopinavir (Kaletra), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), iyo saquinavir (Invirase); bleomycin; capecitabine (Xeloda); karboplatin; chloramphenicol; chlordiazepoxide (Librium, oo ku taal Librax); daawooyinka kolestaroolka sida atorvastatin (Lipitor, in Caduet), fluvastatin (Lescol), iyo simvastatin (Zocor, in Vytorin); cisplatin; clozapine (Fazaclo, Versacloz); cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); diazoxide (Proglycem); digoxin (Lanoxin); sibibramramide (Norpace); disulfiram (Antabuse); doxorubicin (Doxil); doxycycline (Acticlate, Doryx, Monodox, Oracea, Vibramycin); fluorouracil; fluoxetine (Prozac, Sarafem, oo ku taal Symbyax, kuwa kale); fluvoxamine (Luvox); folic acid; fosamprenavir (Lexiva); furosemide (Lasix); H₂ kuwa ka soo horjeedaa sida cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), iyo ranitidine (Zantac); ka hortagga uurka ee hormoonka (kaniiniyada ka hortagga uurka, dhejisyo, giraan, ama irbado); daaweynta beddelka hormoonka (HRT); irinotecan (Camptosar); isoniazid (Laniazid, Rifamate, Rifater); daawooyinka cudurada maskaxda iyo lallabbada; daawooyinka kale ee suuxdinta sida carbamazepine (Carbatrol, Equetro, Tegretol, kuwa kale), ethosuximide (Zarontin), felbamate (Felbatol), lamotrigine (Lamictal), methsuximide (Celontin), oxcarbazepine (Trilepta, Oxtellar XR, phen) ), iyo valproic acid (Depakene); methadone (Dolophine, Methadose); methotrexate (Otrexup, Rasuvo, Trexall, Xatmep); methylphenidate (Daytrana, Concerta, Metadate, Ritalin); mexiletine; nifedipine (Adalat, Procardia), nimodipine (Nymalize), nisoldipine (Sular); omeprazole (Prilosec); steroids-ka afka laga qaato sida dexamethasone, methylprednisolone (Medrol), prednisolone, iyo prednisone (Rayos); paclitaxel (Abraxane, Taxol); paroxetine (Paxil, Pexeva); praziquantel (Biltricide); quetiapine (Seroquel); quinidine (oo ku taal Nuedexta); keydka; rifampin (Rifadin, Rimactane, gudaha Rifamate, Rifater); salicylate xanuun joojiyeyaasha sida asbiriin, choline magnesium trisalicylate, choline salicylate, diflunisal, magnesium salicylate (Doan’s, kuwa kale), iyo salsalate; sertraline (Zoloft); antibiyootikada sulfa; teniposide; theophylline (Elixophyllin, Theo-24, Theochron); ticlopidine; tolbutamide; trazodone; verapamil (Calan, Verelan, oo ku taal Tarka); vigabatrin (Sabril); iyo fitamiin D. Dhaqtarkaaga waxaa laga yaabaa inuu u baahdo inuu badalo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
• u sheeg dhakhtarkaaga waxa ka soo baxa dhirta aad qaadanaysid, gaar ahaan johannesört wort.
• u sheeg dhakhtarkaaga haddii aad waligaa isku aragtay dhibaato beerka ah inta aad qaadaneysid phenytoin. Dhakhtarkaagu uma baahna inuu kaa qaado cirbadda fenytoin.
• u sheeg dhakhtarkaaga haddii aad cabto ama aad waligaa cabto qamri aad u tiro badan. U sheeg dhakhtarkaaga haddii aad soo martay tijaabo shaybaar oo kuu soo gudbisay inaad leedahay cunsur khatar ah oo dhaxalsiisa taas oo ka dhigaysa inay u badan tahay inaad ku yeelato falcelin maqaarka daran fenytoin. Sidoo kale, u sheeg dhakhtarkaaga haddii aad qabtid ama waligaa aad qabtid sonkorow, porphyria (xaalad ay walxaha dabiiciga ah qaarkood ku soo baxaan jirka oo ay u keeni karaan calool xanuun, isbeddel ku yimaada fikirka ama dhaqanka, ama calaamado kale), heerarka albumin ee ku yar dhiig, ama kelyo ama beer xanuun.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Waa inaadan uur yeelan inta aad qaadanaysid phenytoin. Kala hadal dhakhtarkaaga hababka xakameynta dhalmada ee wax ku oolka ah ee aad isticmaali karto inta lagu jiro daaweyntaada. Haddii aad uur yeelato intaad qaadanaysid phenytoin, wac dhakhtarkaaga. Phenytoin wuxuu waxyeelleyn karaa uurjiifka.
• haddii aad qalliin sameyneyso, oo ay ku jiraan qalliinka ilkaha, u sheeg dhakhtarka ama dhakhtarka ilkaha inaad heleyso phenytoin.
• waa inaad ogaataa in daawadani ay sababi karto dawakhaad, lulmo, iyo dhibaatooyin isku xirnaanta. Gaari ha wadin ama ha ku shaqeynin mishiin ilaa aad ka ogaato sida daawadani kuu saameyneyso.
• kala hadal dhakhtarkaaga wixii ku saabsan isticmaalka aaminka ah ee khamriga inta aad qaadanaysid dawadan.
• kala hadal dhakhtarkaaga habka ugu wanaagsan ee loo daryeelo ilkahaaga, ciridkaaga, iyo afkaaga inta lagu guda jiro daaweyntaada loo yaqaan 'phenytoin'. Aad ayey muhiim u tahay inaad si habboon u daryeesho afkaaga si aad u yarayso halista cirridka ee ay keento phenytoin.

Phenytoin wuxuu sababi karaa koror ku yimaada sonkorta dhiigaaga. Kala hadal dhakhtarkaaga calaamadaha sonkorta dhiigga oo sarreeya iyo waxa la sameeyo haddii aad calaamadahaas isku aragto.

Cirbadda Phenytoin waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• dhibaato xagga hurdada ama hurdada ah
• dhaqdhaqaaqa indhaha oo aan la xakamayn karin
• dhaqdhaqaaqa jirka oo aan caadi ahayn
• luminta isuduwidda
• jahwareer
• hadal xanaf leh
• madax xanuun
• isbeddelo dareenkaaga dhadhanka
• calool istaag
• koritaanka timaha aan loo baahnayn
• isku xidhka astaamaha wajiga
• bushimaha oo weynaada
• xad-dhaaf xanjo
• xanuun ama qallooca guska

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamaha soo socda ama kuwa ku taxan qaybta taxaddarrada qaaska ah, isla markiiba wac dhakhtarkaaga:

• barar, midab xumo, ama xanuun meesha la muday ah
• finan
• finan
• cuncun
• barar indhaha, wajiga, cunaha, carrabka, gacmaha, gacmaha, anqawyada, ama lugaha hoose
• neefsashada ama wax liqidda oo ku adkaata
• xabeeb
• qanjirrada oo barara
• lallabbo
• matagid
• hurdi maqaarka ama indhaha
• xanuun qeybta kore ee midig ee caloosha
• daal fara badan
• nabar ama dhiig bax aan caadi ahayn
• dhibco casaan ama guduud ah oo maqaarka ku yaal
• cunto xumo
• astaamaha hargabka oo kale ah
• qandho, hungur xanuun, finan, boogaha afka, ama nabar nabar fudud, ama wajiga oo barara

Cirbadda Phenytoin waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Qaadashada phenytoin waxay kordhin kartaa halista ah inaad horumarisid dhibaatooyinka qanjidhada qanjirada oo ay kujiraan cudurka Hodgkin (kansarka ka bilaabma nidaamka qanjirada). Kala hadal dhakhtarkaaga khataraha isticmaalka daawadan si aad u daaweyso xaaladdaada.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

• dhaqdhaqaaqa indhaha oo aan la xakamayn karin
• luminta isuduwidda
• hadal gaabis ah ama gaabis ah
• daal
• aragga oo xumaada
• gariir aan la koontarooli karin qayb ka mid ah jirka
• lallabbo
• matagid

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu dalban karaa tijaabooyin shaybaarro qaarkood ah si loo hubiyo jawaabtaada duriinka fenytoin.

Kahor baaritaanka shaybaarka, u sheeg dhakhtarkaaga iyo shaqaalaha sheybaarka inaad qaadanayso cirbadda fenytin.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Dilantin^®¶

^¶ Shaygaan sumadda leh kuma sii jiro suuqa. Beddelka guud ayaa la heli karaa.