Qoraa: Joan Hall
Taariikhda Abuurista: 1 Febraayo 2021
Taariikhda Cusboonaysiinta: 20 Noofeembar 2024
Anonim
Glyburide, Chlorpropamide, and Tolbutamide - Sulfonylureas
Dareemoleyad: Glyburide, Chlorpropamide, and Tolbutamide - Sulfonylureas

Qanacsan

Glyburide waxaa loo isticmaalaa cunto iyo jimicsi, mararka qaarkoodna daawooyin kale, ayaa lagu daaweeyaa nooca sonkorowga 2 (xaalad uusan jidhku u isticmaalin insulin si caadi ah, sidaa darteed, ma xakamayn karo qadarka sonkorta dhiiga ku jirta). Glyburide waxay ku jirtaa nooc dawooyin ah oo loo yaqaan sulfonylureas. Glyburide wuxuu yareeyaa sonkorta dhiiga isagoo sababaya xammeetida inay soo saarto insulin (walax dabiici ah oo loo baahan yahay si loo jajabiyo sonkorta jirka) waxayna ka caawisaa jirka inuu u isticmaalo insulin si hufan. Daawadani waxay kaliya ka caawin doontaa yareynta sonkorta dhiigga dadka jirkoodu soo saaro insulin si dabiici ah. Glyburide looma isticmaalo daaweynta nooca 1aad ee sonkorowga (xaalad jidhku aanu soo saarin insulin, sidaa darteed, ma xakamayn karo qadarka sonkorta dhiiga ku jirta) ama ketoacidosis ee sonkorowga (xaalad halis ah oo dhici karta haddii sonkorta dhiigga ee sareeya aan la daaweyn ).

Waqti ka dib, dadka qaba sonkorowga iyo sonkorta dhiigga oo sareeya waxay la kulmi karaan dhibaatooyin halis ah ama naf-gooya, oo ay ku jiraan cudurrada wadnaha, istaroogga, dhibaatooyinka kelyaha, dhaawaca dareemaha, iyo dhibaatooyinka indhaha. Qaadashada daawooyinka (yada), sameynta isbeddelada hab-nololeedka (tusaale, cuntada, jimicsiga, joojinta sigaar cabbista), iyo in si joogto ah loo hubiyo sonkorta dhiiggaaga ayaa gacan ka geysan karta maaraynta cudurka macaanka iyo hagaajinta caafimaadkaaga. Daaweyntani waxay sidoo kale yareyn kartaa fursadahaaga wadno qabad, istaroog, ama dhibaatooyin kale oo la xiriira sonkorowga sida kalyo-baxa, dhaawaca dareemaha (kabuubyo, lugaha qabow ama cagaha; hoos u dhaca awoodda galmada ee ragga iyo dumarka), dhibaatooyinka indhaha, oo ay ku jiraan isbeddelada ama aragga oo kaa luma, ama cirrid xannuun ah. Dhakhtarkaaga iyo bixiyeyaasha kale ee daryeelka caafimaad ayaa kaala hadli doona sida ugu wanaagsan ee loo maareeyo sonkorowgaaga.


Glyburide waxay u timaadaa sidii kiniin afka laga qaato. Waxaa badanaa la qaataa hal jeer maalintii quraacda ama cunnada ugu weyn ee ugu horreysa maalinta. Si kastaba ha noqotee, xaaladaha qaarkood dhakhtarkaagu wuxuu kuu sheegi karaa inaad qaadato glyburide laba jeer maalintii. Si lagaaga caawiyo inaad xasuusato qaadashada glyburide, ku qaado qiyaastii isku wakhti (iskuda) maalin kasta. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado glyburide sida saxda ah ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

Dhakhtarkaagu wuxuu kuugu bilaabi doonaa qadar yar oo glyburide ah wuxuuna si tartiib tartiib ah u kordhin doonaa qiyaastaada haddii loo baahdo. Ka dib markii aad muddo qaadatay glyburide, glyburide ma xakamayn karto sonkorta dhiiggaaga sidii ay u ahayd bilowgii daaweyntaada. Dhakhtarkaaga ayaa laga yaabaa inuu saxo qiyaasta daawadaada hadba sida loogu baahan yahay si daawadu sida ugu fiican kuugu shaqeyso. Hubso inaad u sheegto dhakhtarkaaga sida aad dareemeyso iyo haddii natiijooyinka baaritaanka sonkorta dhiiggaagu ay ka sarreeyeen ama ka hooseeyeen sidii caadiga ahayd wakhti kasta oo daaweyntaada ah.


Glyburide waxay caawisaa xakameynta sonkorta dhiiga laakiin ma daaweyso cudurka macaanka. Sii wad inaad qaadato glyburide xitaa haddii aad dareento fiicnaan. Ha u joojin qaadashada glyburide adigoon la hadlin dhakhtarkaaga.

Daawadan ayaa mararka qaarkood loo qoraa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada glyburide,

  • u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad xasaasiyad ku leedahay glyburide, dawooyinka kale, ama wax ka mid ah waxyaabaha ku jira glyburide. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
  • u sheeg dhakhtarkaaga haddii aad qaadanaysid bosentan (Tracleer). Dhakhtarkaagu wuxuu kuu sheegi karaa inaadan qaadan glyburide haddii aad qaadanaysid dawadan.
  • u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto angiotensin-converting enzyme (ACE) inhibitors sida benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril, ), quinapril (Accupril), ramipril (Altace), iyo trandolapril (Mavik); daawooyinka xinjirowga lidka ku ah ('khafiifiyeyaasha dhiigga') sida warfarin (Coumadin); asbiriin iyo dawooyinka kale ee nonsteroidal anti-bararka (NSAIDs) sida ibuprofen (Advil, Motrin) iyo naproxen (Aleve, Naprosyn); beta beta blockers sida atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), iyo propranolol (Inderal); kaalshiyamka kaalsiyamka sida amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, kuwa kale), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop) Sular), iyo verapamil (Calan, Isoptin, Verelan); chloramphenicol; clarithromycin (Biaxin); cyclosporine (Neoral, Sandimmune); sibibramramide (Norpace); durayaasha ('kaniiniyada biyaha'); fluconazole (Diflucan), fluoxetine (Prozac, Sarafem); gemfibrozil (Lopid), daaweynta beddelka hoormoonka iyo ka hortagga uurka ee hormoonnada (kaniiniyada ka hortagga uurka, balastarro, faraantiyo, xididno, iyo cirbado); insulin ama daawooyin kale si loo daaweeyo sonkorta dhiigga ee sareeya ama sonkorowga; isoniazid (INH); MAO xakameeyayaasha sida isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), iyo tranylcypromine (Parnate); daawooyinka neefta iyo hargabka; daawooyinka cudurada maskaxda iyo lallabbada; miconazole (Monistat); niacin; dawooyinka afka laga qaato sida dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), iyo prednisone (Deltasone); phenytoin (Dilantin); probenecid (Benemid); antibiyootikada quinolone iyo fluoroquinolone sida cinoxacin (Cinobac), ciprofloxacin (Cipro), enoxacin (Penetrex), gatifloxacin (Tequin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox) (nGidix acid) ), ofloxacin (Floxin), sparfloxacin (Zagam), trovafloxacin iyo isku darka alatrofloxacin (Trovan); rifampin; salicylate xanuun joojiyeyaasha sida choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan’s, kuwa kale), iyo salsalate (Argesic, Disalcid, Salgesic); antibiyootikada sulfa sida co-trimoxazole (Bactrim, Septra); sulfasalazine (Azulfidine); iyo dawooyinka tayroodhka. Sidoo kale hubi inaad u sheegto dhakhtarkaaga ama farmashiistaha haddii aad joojiso qaadashada wax daawo ah inta aad qaadanaysid glyburide. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
  • u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa qabay yaraanta G6PD (xaalad la iska dhaxlo oo sababi kara burbur deg-deg ah oo unugyada dhiigga cas ama hemolytic anemia); haddii aad qabto cillad hormoon oo ku lug leh qanjidhada 'adrenal', 'pituitary', ama qanjirka 'thyroid'; ama haddii aad qabtid wadne, kalyo, ama beer xanuun.
  • u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato intaad qaadanaysid glyburide, wac dhakhtarkaaga.
  • kala hadal dhakhtarkaaga khataraha iyo waxtarka u leh qaadashada glyburide haddii aad tahay 65 sano jir ama ka weyn. Dadka waayeelka ah waa inaysan badiyaa qaadan glyburide sababtoo ah ma ahan mid amaan ah ama waxtar u leh daawooyinka kale ee loo isticmaali karo in lagu daaweeyo isla xaaladaas.
  • haddii aad qalliin samaynayso, oo ay ku jiraan qalliinka ilkaha, u sheeg dhakhtarka ama dhakhtarka ilkaha inaad qaadanayso glyburide.
  • Weydii dhakhtarkaaga wixii ku saabsan isticmaalka aaminka ah ee khamriga inta aad qaadanaysid glyburide. Aalkoladu waxay ka dhigi kartaa waxyeelada ka timaadda glyburide. Cunitaanka aalkolada inta aad qaadanaysid glyburide sidoo kale marar dhif ah ayay sababi kartaa astaamo sida dheecaanka (casaanka wajiga), madax xanuun, lallabbo, matag, xabad xanuun, daciifnimo, araga oo xumaada, jahwareer maskaxeed, dhidid, xiiq, neefsashada oo dhib ah, iyo walwal.
  • qorsheyso inaad iska ilaaliso soo-gaadhista qorraxda aan loo baahnayn ama daba dheeraatay iyo inaad xidhato dhar ilaaliya, muraayadaha indhaha, iyo muraayadda qorraxda. Glyburide ayaa laga yaabaa inuu maqaarkaaga u nuglaado iftiinka qoraxda.
  • Weydii dhakhtarkaaga waxa la sameeyo haddii aad xanuunsato, infekshin kugu dhaco ama qandho, walwal aan caadi ahayn aad qabto, ama aad dhaawacdid. Xaaladahan waxay saameyn ku yeelan karaan sonkorta dhiiggaaga iyo xaddiga glyburide ee aad u baahan karto.

Hubso inaad raacdo dhammaan jimicsiga iyo talooyinka cuntada ee dhakhtarkaagu ama nafaqeeyahaagu kuu qoro. Waa muhiim in la cuno cunto caafimaad leh, jimicsi joogto ah, iyo in miisaan la dhimo haddii loo baahdo.


Kahor intaadan bilaabin qaadashada glyburide, weydii dhaqtarka waxa ay tahay inaad sameyso haddii aad ilowdo inaad qaadatid qiyaas. Qor jihooyinkaan si aad mar dambe u tixraaci karto.

Sida caadiga ah, qaado qiyaasta la seegay isla marka aad xusuusatoba. Haddii ay ku dhowdahay waqtiga qiyaasta xigta, ka bood qiyaasta la seegay oo sii wad jadwalkaaga qiyaasta daawada ee caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Dawadani waxay sababi kartaa isbeddel ku dhaca sonkorta dhiiggaaga. Waa inaad ogaataa astaamaha sonkorta dhiiga oo hooseysa iyo kuwa sare iyo waxa la sameeyo haddii aad leedahay astaamahan.

Glyburide waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

  • lallabbo
  • buuxinta caloosha sare
  • laabjeex
  • finan

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac dhakhtarkaaga isla markiiba:

  • hurdi maqaarka ama indhaha
  • saxaro midab khafiif ah leh
  • kaadi madow
  • xanuun qeybta kore ee midig ee caloosha
  • nabar ama dhiig bax aan caadi ahayn
  • shuban
  • qandho
  • cune xanuun
  • bararka indhaha, wejiga, dibnaha, carrabka, ama cunaha

Glyburide waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Hal daraasad, dadka qaatay daawo la mid ah glyburide si loo daweeyo sonkorowgooda waxay u dhowdahay inay u dhintaan dhibaatooyinka wadnaha marka loo eego dadka lagu daweeyay insulin-ta iyo isbedelka cuntada. Takhtarkaaga kala hadal halista qaadashada glyburide.

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi heerkulka qolka oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha).

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara astaamaha hypoglycemia iyo sidoo kale kuwa soo socda:

  • qalal
  • miyir beelid

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Heerarka sonkorta dhiiggaaga sooman iyo hemoglobin glycosylated (HbA1c) waa in si joogto ah loo hubiyaa si loo ogaado jawaabtaada glyburide. Dhakhtarkaagu wuxuu dalban karaa baaritaano kale oo shaybaar ah si loo hubiyo jawaabtaada glyburide. Dhakhtarkaaga ayaa sidoo kale kuu sheegi doona sida loo hubiyo jawaabtaada daawadan adoo ku cabbiraya heerarka sonkorta dhiiggaaga guriga. Si taxaddar leh u raac tilmaamahaas.

Waa inaad marwalba xidhataa jijin aqoonsiga kaadi macaanka si loo hubiyo inaad hesho daaweyn sax ah markay tahay xaalad degdeg ah.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

  • DiaBeta®
  • Glynase®
  • Micronase®

Shaygaan sumadda leh kuma sii jiro suuqa. Beddelka guud ayaa la heli karaa.

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