BRCA Tijaabada Hiddeynta

Qanacsan

• Waa maxay baaritaanka hiddo-wadaha BRCA?
• Maxaa loo adeegsadaa?
• Maxaan ugu baahanahay baaritaanka hidda-socodka ee BRCA?
• Maxaa dhacaya inta lagu jiro baaritaanka hidda-socodka ee BRCA?
• Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?
• Ma jiraan wax khatar ah oo imtaxaanku leeyahay?
• Maxay natiijooyinka ka dhigan yihiin?
• Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado baaritaanka hidda-socodka ee BRCA?
• Tixraacyo

Waa maxay baaritaanka hiddo-wadaha BRCA?

BRCA hidde ahaan waxay u egtahay isbeddelo, oo loo yaqaan 'mutations', hiddo-wadaha la yiraahdo BRCA1 iyo BRCA2. Hiddo-wadayaashu waa qaybo ka mid ah hidde-sideyaasha DNA ee laga soo gudbiyay hooyadaa iyo aabbahaa Waxay sitaan macluumaad go'aamiya astaamahaaga gaarka ah, sida dhererka iyo midabka indhaha. Hidda-wadaha ayaa sidoo kale mas'uul ka ah xaaladaha caafimaad qaarkood. BRCA1 iyo BRCA2 waa hiddo-wadayaal difaaca unugyada iyagoo sameeya borotiinno ka caawiya kahortagga burooyinka inay sameysmaan.

Isbeddel ku dhaca hiddo-wadaha BRCA1 ama BRCA2 wuxuu sababi karaa dhaawac unug oo u horseedi kara kansar. Haweenka leh hidde-wadaha BRCA ee isbeddelay waxay halis sare ugu jiraan inay qaadaan kansarka naasaha ama ugxansidaha. Ragga qaba hiddo-wadaha BRCA ee isbeddelay ayaa halis sare ugu jira inay qaadaan kansarka naasaha ama qanjirka 'prostate'. Ma aha in qof kasta oo dhaxla isbadal ku dhaca BRCA1 ama BRCA2 uusan ku dhici doonin kansar. Waxyaabaha kale, oo ay ku jiraan noloshaada iyo deegaankaaga, waxay saameyn ku yeelan karaan halista kansarkaaga.

Haddii aad ogaato inaad leedahay isbeddel BRCA ah, waxaad awoodi kartaa inaad qaado tallaabooyin aad ku ilaalineyso caafimaadkaaga.

Magacyada kale: Tijaabada hiddo-wadaha BRCA, hiddo-wadaha BRCA 1, hiddo-wadaha BRCA 2, hiddo-u nuglaanta kansarka naasaha1, hiddo-wadaha u nugul kansarka naasaha 2

Maxaa loo adeegsadaa?

Tijaabadan waxaa loo adeegsadaa in lagu ogaado haddii aad qabto hiddo-wadaha BRCA1 ama BRCA2. Isbedelka hiddo-wadaha BRCA wuxuu kordhin karaa halista aad ugu qaadi karto kansarka.

Maxaan ugu baahanahay baaritaanka hidda-socodka ee BRCA?

Tijaabada BRCA laguma talinayo dadka intiisa badan. Isbedelada hiddo-wadaha BRCA waa dhif iyo naadir, wuxuu saameeyaa oo keliya qiyaastii boqolkiiba 0.2 dadka Mareykanka. Laakiin waxaad u baahan kartaa baaritaankaan haddii aad u maleyneyso inaad qatar ugu jirto inaad ku dhacdo isbeddellada. Waxay u badan tahay inaad ku dhacdo isbeddel BRCA haddii aad:

• Uu qabo ama uu yeesho kansarka naasaha oo la ogaadey kahor da'da 50 jir
• Uu leeyahay ama uu ku dhacay kansarka naasaha labada naas
• Aad leedahay ama yeelatay kansarka naasaha iyo ugxansidaha
• Yeelo hal ama in kabadan xubnaha qoyska oo qaba kansarka naasaha
• Hayso qaraabo lab ah oo qaba kansarka naasaha
• Hayso qof qaraabo ah oo horey looga helay isbadal ku dhacay BRCA
• Ka soo jeedo Ashkenazi (Bariga Yurub) isirka Yuhuudda. Isbedelada BRCA ayaa aad ugu badan kooxdan marka loo eego dadweynaha guud. Is-beddelka BRCA sidoo kale wuxuu ku badan yahay dadka ka yimid qaybaha kale ee Yurub, oo ay ku jiraan, Iceland, Norway, iyo Danmark.

Maxaa dhacaya inta lagu jiro baaritaanka hidda-socodka ee BRCA?

Xirfadlaha daryeelka caafimaadka ayaa tijaabo dhiig ka qaadi doona xididka gacantaada, isagoo isticmaalaya cirbad yar. Kaddib cirbada la geliyo, qadar yar oo dhiig ah ayaa lagu ururin doonaa tuubada baaritaanka ama fijaan. Waxaa laga yaabaa inaad dareento xoog wax yar ah markii irbadda ay soo galayso ama ay ka baxeyso. Tani badanaa waxay qaadataa in ka yar shan daqiiqo.

Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?

Uma baahnid wax diyaargarow gaar ah oo loogu talagalay baaritaanka BRCA. Laakiin waxaa laga yaabaa inaad rabto inaad la kulanto lataliyaha hiddaha marka hore si aad u ogaato haddii baaritaanka uu adiga kugu habboon yahay. La-taliyahaada ayaa laga yaabaa inuu kaala hadlo halista iyo faa'iidooyinka baaritaanka hidda-socodka iyo natiijooyinka kala duwan ee macnaheedu noqon karo.

Sidoo kale waa inaad ka fikirtaa sidii aad ku heli lahayd la-talin hidde ah baaritaankaaga ka dib. La-taliyahaada ayaa ka wada hadli kara sida natiijooyinkaagu saameyn ugu yeelan karaan adiga iyo qoyskaaga, caafimaad ahaan iyo shucuur ahaanba.

Ma jiraan wax khatar ah oo imtaxaanku leeyahay?

Khatar aad u yar baa jirta in dhiig lagaa qaado. Waxaa laga yaabaa inaad xanuun yar ama nabar ku yeelato barta irbadda lagu muday, laakiin astaamaha badankood si dhakhso leh ayey u baxaan.

Maxay natiijooyinka ka dhigan yihiin?

Natiijooyinka badankood waxaa lagu sifeeyaa inay yihiin kuwo taban, aan la hubin, ama togan, oo caadi ahaan loola jeedo kuwa soo socda:

• Natiijo xun macnaheedu waa lama badal hiddo-wadaha BRCA, laakiin macnaheedu maahan inaadan waligaa kansar kugu dhici doonin.
• Natiijo aan la hubin macnaheedu waa nooc ka mid ah hiddo-wadaha BRCA ayaa la helay, laakiin waxaa laga yaabaa ama aan lala xiriirinin khatarta kansarka oo sii kordheysa. Waxaad u baahan kartaa baaritaanno dheeri ah iyo / ama kormeer haddii natiijooyinkaaga aan la hubin.
• Natiijo togan macnaheedu waa isbadal ku yimid BRCA1 ama BRCA2 ayaa laga helay. Is-beddelladani waxay khatar weyn kuu gelinayaan inaad ku dhacdo kansarka. Laakiin qof kasta oo isbeddel ku dhaca kuma dhaco kansarka.

Waxay qaadan kartaa dhowr toddobaad in la helo natiijooyinkaaga. Haddii aad su'aalo ka qabtid natiijooyinkaaga, la hadal daryeel caafimaad bixiyahaaga iyo / ama la-taliyahaaga hidda-socodka.

Wax badan ka baro baaritaanka shaybaarka, kala duwanaanshaha tixraaca, iyo fahamka natiijooyinka.

Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado baaritaanka hidda-socodka ee BRCA?

Haddii natiijooyinkaagu muujiyaan inaad leedahay isbeddel hidde-side ah BRCA, waxaad qaadi kartaa tallaabooyin yareyn kara halista kansarka naasaha. Kuwaas waxaa ka mid ah:

• Tijaabooyin badan oo soo noqnoqda ah oo lagu baaro kansarka, sida raajada mammograamyada iyo ultrasounds Kansarku way fududahay in la daweeyo marka laga helo heerarka hore.
• Qaadashada kaniiniyada ka hortagga uurka waqti xaddidan. Qaadashada kaniiniyada ka hortagga uurka ugu badnaan shan sano ayaa la muujiyey inay yareyneyso halista kansarka ugxansidaha ee dumarka qaarkood ee qaba isbeddelka hiddo-wadaha BRCA. Qaadashada kaniiniyada in ka badan shan sano si loo yareeyo kansarka laguma talinayo. Haddii aad qaadanaysay kaniiniyada ka hortagga uurka ka hor intaadan qaadin baaritaanka BRCA, u sheeg bixiyahaaga daryeelka caafimaadka inta sano ee aad jirtay markii aad qaadatay kaniiniyada iyo muddada. Isaga ama iyada ayaa markaa kugula talin doona inaad sii wadato qaadashada iyo in kale.
• Qaadashada dawooyinka la dagaallanka kansarka. Daawooyinka qaarkood, sida midka loo yaqaan tamoxifen, ayaa la muujiyey inay yareyneyso halista haweenka halista sare ugu jira kansarka naasaha.
• Qalliin lagu sameeyo, oo loo yaqaan mastektomi ka hortag ah, si looga saaro unugyada naaska oo caafimaad qaba. Mastektomi ka hortag ah ayaa la muujiyay inuu yareynayo halista kansarka naasaha iyadoo boqolkiiba 90 boqolkiiba dumarka qaba hiddo-wadaha BRCA. Laakiin kani waa qalliin weyn, keliya waxaa lagula taliyaa dumarka halista ugu weyn ugu jira kansarka.

Waa inaad la hadashaa bixiyaha xanaanada caafimaadkaaga si aad u aragto talaabooyinka adiga kugu habboon.

Tixraacyo

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Macluumaadka ku yaal boggan waa in aan loo isticmaalin beddel daryeel caafimaad oo xirfad leh ama talo. La xiriir bixiye daryeel caafimaad haddii aad su'aalo ka qabtid caafimaadkaaga.