Hypogonadism: waa maxay, astaamaha ugu waaweyn iyo daaweynta

Qanacsan

• Calaamadaha ugu waaweyn
• 1. hypogonadism-ka ragga
• 2. hypogonadism-ka dumarka
• 3. Hypogonadotrophic hypogonadism
• Sababaha suuragalka ah
• 1. hypogonadism-ka aasaasiga ah
• 2. hypogonadism-ka labaad
• Sida daaweynta loo sameeyo
• Dhibaatooyinka suurtagalka ah

Hypogonadism waa xaalad ugxansidaha ama xiniinyaha aan soo saarin hormoonno ku filan, sida estrogenka haweenka iyo testosterone ragga, oo door muhiim ah ka ciyaara koritaanka iyo horumarka xilliga qaan-gaarnimada.

Xaaladdani waxay horumarin kartaa inta lagu jiro horumarka uurjiifka inta lagu jiro uurka, oo u muuqda dhalashada, laakiin waxay sidoo kale u muuqan kartaa da 'kasta, badanaa sababo nabarro ama infekshannada ugxan sidaha ama xiniinyaha.

Hypogonadism wuxuu sababi karaa madhalaysnimo, maqnaanshaha qaangaarnimada, caadada ama koritaanka liita ee xubinta galmada ragga. Daaweynta hypogonadism waa inuu muujiyaa dhakhtarku wuxuuna ujeedkiisu yahay inuu xakameeyo heerarka hoormoonka oo laga fogaado dhibaatooyinka, iyo isticmaalka daawooyinka hoormoonka ama qalliinka ayaa laga yaabaa inay lagama maarmaan noqoto.

Calaamadaha ugu waaweyn

Hypogonadism wuxuu bilaabmi karaa inta lagu jiro koritaanka uurjiifka, ka hor qaan-gaarnimada ama xilliga qaan-gaarnimada iyo guud ahaan, calaamadaha iyo astaamuhu waxay kuxiran yihiin marka xaaladdu timaaddo iyo jinsiga qofka:

1. hypogonadism-ka ragga

Hypogonadism-ka ragga waxaa sababa hoos u dhaca ama maqnaanshaha wax soo saarka testosterone ee xiniinyaha, soo bandhiga astaamo kala duwan iyadoo loo eegayo heerka nolosha:

• Ilmaha: koritaanka daciifka ah ee xubnaha galmada ee dibedda ayaa dhici kara sababtoo ah soosaarka testosterone oo hooseeya inta lagu jiro horumarka uurjiifka. Waxay kuxirantahay goorta hypogonadismku kobcayo iyo xaddiga testosterone ee jirta, canugga, oo hidde ahaan u ah wiil, waxaa ku dhalan kara xubnaha taranka ee haweenka, xubnaha taranka ee sida muuqata aan ahayn lab ama dhedig ama xubinta taranka ee ragga oo aan horumarin;
• Wiilasha qaangaarnimada kahor: calaamadaha hypogonadism waa naafonimo koritaanka xubinta taranka, muruqyada iyo timaha jirka, muuqaalka naasaha, maqnaanshaha isbeddelada codka, caadi ahaan xilliga qaan-gaarnimada, iyo koritaanka xad dhaafka ah ee gacmaha iyo lugaha ee la xiriira jirridda;
• Ragga qaangaadhnimada kadib: xaddiga timaha jidhka oo yaraada, murqaha oo yaraada iyo dufanka jidhka oo kordha, hawlgab kacsi iyo rabitaan jinsi oo hooseeya. Waxa kale oo laga yaabaa inay hoos u dhacdo soo saarista shahwada, taas oo sababi karta dhalmo la’aan ama dhibaato ku ah uur yeelashada lammaanaha.

Baadhista hypogonadism waxaa sameeya dhaqtarka cudurada caruurta ama dhakhtarka kaadi mareenka, kuna saleysan astaamaha, taariikhda caafimaad iyo baaritaanka jireed ee dhaqtarka uu ku hubinayo horumarka xiniinyaha, guska iyo timaha jirka, iyo waliba sida ugu macquulsan horumarinta naasaha. Haddii aad ka shakisan tahay hypogonadism-ka ragga, dhakhtarku waa inuu amro baaritaanno lagu cabbirayo heerarka hormoonnada sida testosterone, FSH iyo LH, iyo sidoo kale falanqaynta shahwada, iyadoo loo marayo baaritaanka shahwada. Raadi sida loo sameeyo shahwada shahwada.

2. hypogonadism-ka dumarka

Hypogonadism-ka dumarka oo dhaca sababo la xiriira hoos u dhaca ama maqnaanshaha soosaarka estrogen ee ugxansidaha oo leh calaamado kala duwan oo ku xiran heerka nolosha haweeneyda, oo ay ka mid yihiin:

• Gabdhaha ka hor qaangaarnimada: caadiyan caadada ugu horeysa waxay bilaabataa kadib markay 14 jirsato ama waxaa jira gabi ahaanba maqnaanshaha caadada, taas oo saameyn ku yeelata koritaanka naasaha iyo timaha xubinta taranka;
• Haweenka ka dib qaan-gaarnimada: caadada aan caadiga ahayn ama hakad ku yimaadda caadada ayaa dhici kara, tamar la'aan, isbeddel xagga niyadda ah, rabitaanka galmada oo yaraada, timaha jidhka oo yaraada, shidmada kulul iyo dhibaatada uur qaadista.

Baadhista hypogonadism-ka dumarka waxaa sameeya dhakhtarka carruurta ama dhakhtarka dumarka, marka loo eego da'da, oo ku saleysan taariikhda caafimaad, da'da caadada ugu horreysa, caadada caadada iyo baaritaanka jirka si loo qiimeeyo horumarka naasaha iyo timaha. Intaas waxaa sii dheer, dhakhtarku waa inuu amraa baaritaano shaybaar si loo cabbiro heerarka hormoonnada FSH, LH, estrogen, progesterone iyo prolactin, iyo baaritaannada sawirka sida ultrasound ee miskaha.

3. Hypogonadotrophic hypogonadism

Hypogonadotropic hypogonadism, sidoo kale loo yaqaan hypogonadism-ka dhexe, wuxuu ku dhici karaa dhalashada ragga iyo dumarka labadaba, laakiin sidoo kale wuu ku kori karaa da 'kasta.

Noocan hypogonadism wuxuu ku dhacaa isbeddelada ku dhaca hypothalamus ama qanjirka 'pituitary gland', oo ku yaal maskaxda, kuwaas oo mas'uul ka ah soo saarista hormoonnada kiciya ugxanta ama xiniinyaha si ay u soo saaraan hormoonadooda. Xaaladdan oo kale, astaamaha ugu caamsan waa madax xanuun, aragga oo adkaada sida aragga oo labalaabma ama aragga oo kaa luma, iyo soosaarida caanaha naasaha

Ciladaha hypogonadotrophic hypogonadism waxaa sameeya dhakhtarka iyadoo lagu saleynayo astaamaha iyo iyadoo loo marayo baaritaanka muuqaalka sida sawirka maskaxeed ee magnetic resonance.

Sababaha suuragalka ah

Sababaha keena hypogonadism-ka waxaa loo kala saari karaa iyadoo loo eegayo nooca qanjirka uu saameeyay waxaana ka mid ah:

1. hypogonadism-ka aasaasiga ah

Hypogonadism-ka aasaasiga ah badanaa waxaa sababa:

• Cudurada iswada, kilyaha ama beerka;
• Dhibaatooyinka hiddo-wadaha, sida Turner Syndrome, ee haweenka, iyo Klinefelter Syndrome, ragga;
• Cudurka loo yaqaan 'Cryptorchidism' oo xiniinyaha uusan ku soo degin xinjirta wiilasha markay dhashaan;
• Qaamo-qashiirta ku dhaca wiilasha;
• Caado-dayska hore ee haweenka;
• Cudurka ugxan-sidaha ee 'polycystic ovary syndrome' ee haweenka;
• Infekshanka sida jabtada dumarka;
• Daaweynta shucaaca ama kemotherabi ee daaweynta kansarka maadaama ay saameyn ku yeelan karto soo saarista hormoonnada galmada.

Noocan hypogonadism, ugxan sidaha ama xiniinyaha si sax ah uma shaqeeyaan, iyagoo soo saaraya wax yar ama aan laheyn hormoon galmo, maxaa yeelay kama jawaabaan kicinta maskaxda.

2. hypogonadism-ka labaad

Hypogonadism Secondary waxaa badanaa keena:

• Dhiigbax aan caadi ahayn;
• Dhibaatooyinka hidaha sida Kallmann's syndrome;
• Ciladaha nafaqada;
• Cayilka;
• Birta dhiiga ku jirta oo xad dhaaf ah;
• Shucaac;
• Infekshanka HIV;
• Burooyinka pituitary.

Marka loo eego hypogonadism-ka labaad, waxaa jira hoos u dhac ama maqnaanshaha wax soo saarka hoormoonka ee maskaxda, sida FSH iyo LH, kuwaas oo mas'uul ka ah kicinta xiniinyaha ama ugxan sidaha si ay u soo saaraan hormoonadooda galmada.

Sida daaweynta loo sameeyo

Daaweynta hypogonadism waa in had iyo jeer lagu sameeyaa talobixin caafimaad waxaana ka mid noqon kara daawooyinka hoormoonka si loogu beddelo hormoonnada hormoonka iyo estrogen ee haweenka, iyo testosterone ragga.

Haddii sababtu tahay dhibaatada pituitary, daaweynta sidoo kale waxaa lagu samayn karaa hormoonnada pituitary si loo kiciyo soo saarida shahwada ragga ama ugxaanta dumarka sidaasna dib loogu soo celiyo taranka. Intaas waxaa sii dheer, xaalada buro ku jirta qanjirka 'pituitary gland', qalliin ayaa loo baahan karaa si looga saaro burooyinka, loo isticmaalo daawooyinka, shucaaca ama daaweynta hoormoonka.

Dhibaatooyinka suurtagalka ah

Dhibaatooyinka uu hypogonadism sababi karo waa:

• Xubnaha taranka ee aan caadiga ahayn ee ragga;
• Kobcinta naasaha ee ragga;
• Cilad aan caadi ahayn oo ragga ah;
• Khatarta sii kordheysa ee cudurada wadnaha iyo xididada;
• Miisaanka jidhka oo kordhay;
• Lumida muruqyada;
• Madhalaysnimo;
• Lafaha.

Intaa waxaa sii dheer, hypogonadism wuxuu saameyn ku yeelan karaa isku kalsoonaanta ragga iyo dumarka wuxuuna sababi karaa dhibaatooyin xiriirka jaceylka ama dhibaatooyinka nafsaaniga ah sida niyadjabka, walwalka ama aqbalida jirka laftiisa.