Tijaabada Murqaha Murqaha

Qanacsan

• Waa maxay baaritaanka jirka ee muruqa jilicsan (SMA)?
• Maxaa loo adeegsadaa?
• Maxaan ugu baahanahay imtixaanka SMA?
• Maxaa dhacaya inta lagu jiro baaritaanka SMA?
• Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?
• Ma jiraan wax khatar ah oo imtaxaanku leeyahay?
• Maxay natiijooyinka ka dhigan yihiin?
• Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado imtixaanka SMA?
• Tixraacyo

Waa maxay baaritaanka jirka ee muruqa jilicsan (SMA)?

Tijaabadani waxay raadineysaa unugyada difaaca jirka ee muruqyada (SMAs) ee dhiiga kujira. Antibody a muruqa (SMA) waa nooc ka mid ah antibody loo yaqaan autoantibody. Caadi ahaan, nidaamkaaga difaaca ayaa sameeya unugyada difaaca jirka si ay u weeraraan walxaha shisheeye sida fayrasyada iyo bakteeriyada. Autoantibody wuxuu si qalad ah u weeraraa unugyada jirka iyo unugyada. SMAs waxay weeraraan unugyada muruqyada jilicsan ee beerka iyo qaybaha kale ee jirka.

Haddii SMAs laga helo dhiiggaaga, waxay u badan tahay inaad qabtid cagaarshowga iswada. Cudurka cagaarshowga ee 'Autoimmune hepatitis' waa cudur nidaamka difaaca jirka uu ku weeraro unugyada beerka. Waxaa jira laba nooc oo hepatitis autoimmune:

• Nooca 1, nooca ugu badan ee cudurka. Nooca 1aad wuxuu ku dhacaa dumarka in kabadan ragga. Waxay sidoo kale ku badan tahay dadka sidoo kale leh cudur kale oo isdifaaca jirka.
• Nooca 2, nooc aan caadi ahayn oo cudurka ah. Nooca 2aad wuxuu badanaa ku dhacaa gabdhaha da'doodu u dhaxeyso 2 ilaa 14 sano.

Cudurka cagaarshowga ee 'Autoimmune hepatitis' waxaa lagu maamuli karaa daawooyinka xakameynaya nidaamka difaaca jirka. Daaweyntu waxay waxtar badan leedahay marka cilladda la helo goor hore. Daaweyn la'aan, hepatitis autoimmune waxay sababi kartaa dhibaatooyin caafimaad oo daran, oo ay kujiraan cirrhosis iyo beerka oo shaqeynaya.

Magacyada kale: antibody-muruqa antibody, ASMA, actin antibody, ACTA

Maxaa loo adeegsadaa?

Tijaabada 'SMA' waxaa ugu horreyn loo adeegsadaa in lagu baaro cagaarshowga difaaca jirka. Waxaa sidoo kale loo isticmaalaa in lagu ogaado in cilladdu tahay nooca 1 ama nooca 2.

Tijaabooyinka SMA sidoo kale waxaa badanaa loo isticmaalaa baaritaanno kale si looga caawiyo xaqiijinta ama meesha looga saaro ogaanshaha cudurka hepatitis-ka jirka. Imtixaanadan kale waxaa ka mid ah:

• Baadhitaan ku saabsan unugyada difaaca jirka ee F-actin. F-actin waa borotiin laga helo unugyada muruqyada jilicsan ee beerka iyo qaybaha kale ee jirka. Unugyada difaaca jirka ee F-actin waxay weeraraan unugyadan caafimaadka qaba.
• ANA (antinuclear antibody) tijaabada. ANAs-ku waa unugyada difaaca jirka ee weerara xudunta (xarunta) unugyada caafimaadka qaba qaarkood.
• ALT (alanine transaminase) iyo AST (aspartate aminotransferase) baaritaanada. ALT iyo AST waa laba enzym oo uu sameeyo beerka.

Maxaan ugu baahanahay imtixaanka SMA?

Waxaad u baahan kartaa baaritaankaan haddii adiga ama ilmahaagu aad isku aragtaan astaamaha hepatitis-ka jirka. Kuwaas waxaa ka mid ah:

• Daal
• Jaundice (xaalad sababa in maqaarkaaga iyo indhahaaga huruud isu beddelaan)
• Calool xanuun
• Xanuun wadajir ah
• Lallabbo
• Nabarrada maqaarka
• Cunto xumo
• Kaadi midab madow ah

Maxaa dhacaya inta lagu jiro baaritaanka SMA?

Xirfadlaha daryeelka caafimaadka ayaa tijaabo dhiig ka qaadi doona xididka gacantaada, isagoo isticmaalaya cirbad yar. Kaddib cirbada la geliyo, qadar yar oo dhiig ah ayaa lagu ururin doonaa tuubada baaritaanka ama fijaan. Waxaa laga yaabaa inaad dareento xoog wax yar ah markii irbadda ay soo galayso ama ay ka baxeyso. Tani badanaa waxay qaadataa in ka yar shan daqiiqo.

Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?

Uma baahnid wax diyaargarow gaar ah oo loogu talagalay imtixaanka SMA.

Ma jiraan wax khatar ah oo imtaxaanku leeyahay?

Khatar aad u yar baa jirta in dhiig lagaa qaado. Waxaa laga yaabaa inaad xanuun yar ama nabar ku yeelato barta irbadda lagu muday, laakiin astaamaha badankood si dhakhso leh ayey u baxaan.

Maxay natiijooyinka ka dhigan yihiin?

Haddii natiijooyinkaagu muujiyaan xaddi badan oo unugyada difaaca jirka ee 'SMA', waxay u badan tahay inay ka dhigan tahay inaad haysato nooca 1aad ee cudurka cagaarshow ee isdifaaca. Qadar yar ayaa macnaheedu noqon karaa inaad qabto nooca 2aad ee cudurka.

Haddii aan la helin SMA-yada, waxay ka dhigan tahay in astaamaha beerkaaga ay sababaan wax ka duwan cagaarshowga iswada. Bixiyahaaga daryeelka caafimaad wuxuu ubaahan doonaa inuu dalbado baaritaano dheeri ah si loo ogaado cudurka.

Haddii aad su'aalo ka qabtid natiijooyinkaaga, la hadal daryeel caafimaad bixiyahaaga.

Wax badan ka baro baaritaanka shaybaarka, kala duwanaanshaha tixraaca, iyo fahamka natiijooyinka.

Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado imtixaanka SMA?

Haddii natiijooyinkaagu muujiyeen in adiga ama ilmahaagu aad leedihiin unugyada difaaca jirka ee 'SMA', bixiyahaaga ayaa laga yaabaa inuu dalbado cad ka-qaadista beerka si loo xaqiijiyo ogaanshaha cudurka cagaarshow ee is-difaaca jirka Cad ka-qaadis (biopsy) ayaa ah nidaam soo saaraya qayb yar oo unug ka mid ah si loo baaro.

Tixraacyo

1. Aasaaska Beerka Mareykanka. [Internetka]. New York: Aasaaska Beerka Mareykanka; c2017. Cudurka Cagaarshowga ee 'Autoimmune Hepatitis' [oo la soo xigtay 2019 Aug 19]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://liverfoundation.org/for-patients/about-the-liver/diseases-of-the-liver/autoimmune-hepatitis/#information-for-the-newly-diagnosed
2. Tijaabooyinka Shaybaarka ee Internetka [Internetka] Washington D.C; Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2019. Antinuclear Antibody (ANA) [waa la cusbooneysiiyay 2019 Mar 5; daliishaday 2019 Aug 19]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/tests/antinuclear-antibody-ana
3. Tijaabooyinka Shaybaarka ee Internetka [Internetka] Washington D.C; Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2019. Autoantibodies [cusbooneysiiyay 2019 Meey 28; daliishaday 2019 Aug 19]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/tests/autoantibodies
4. Tijaabooyinka Shaybaarka ee Internetka [Internetka] Washington D.C; Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2019. Murqaha Murqaha Murugsan (SMA) iyo F-actin Antibody [la cusbooneysiiyay 2019 Meey 13; daliishaday 2019 Aug 19]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/tests/smooth-muscle-antibody-sma-and-f-actin-antibody
5. Mayo Clinic [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1998–2019. Cagaarshowga otomatigga ah: Calaamadaha iyo sababaha; 2018 Sep 12 [daliishaday 2019 Aug 19]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.mayoclinic.org/diseases-conditions/autoimmune-hepatitis/symptoms-causes/syc-20352153
6. Machadka Kansarka Qaranka [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Qaamuuska NCI ee Shuruudaha Kansarka: biopsy; [waxaa daliishaday 2020 Aug 9]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/biopsy
7. Machadka Wadnaha, Sambabka, iyo Machadka Dhiiga [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Tijaabooyinka Dhiigga [la sheegay 2019 Aug 19]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.nhlbi.nih.gov/health-topics/blood-tests
8. Machadka Qaranka ee Arthritis-ka iyo Cudurrada Muruqyada iyo Maqaarka [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Cudurada Autoimmune [xigasho 2019 Aug 19]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.niams.nih.gov/health-topics/autoimmune-diseases
9. Machadka Qaranka ee Sonkorowga iyo Cudurada Dheefshiidka iyo Kelyaha [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Qeexitaanka iyo Xaqiiqda Cudurka Cagaarshowga ee loo yaqaan 'Autoimmune Hepatitis' 2018 Meey [daliishaday 2019 Aug 19]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://www.niddk.nih.gov/health-information/liver-disease/autoimmune-hepatitis/definition-facts
10. Machadka Qaranka ee Sonkorowga iyo Cudurada Dheefshiidka iyo Kelyaha [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Ciladaha Cudurka Cagaarshowga ee 'Autoimmune Hepatitis'; 2018 Meey [daliishaday 2019 Aug 19]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://www.niddk.nih.gov/health-information/liver-disease/autoimmune-hepatitis/diagnosis
11. Machadka Qaranka ee Sonkorowga iyo Cudurada Dheefshiidka iyo Kelyaha [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Astaamaha iyo Sababaha keena Cudurka Cagaarshowga ee loo yaqaan 'Autoimmune Hepatitis'; 2018 Meey [daliishaday 2019 Aug 19]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://www.niddk.nih.gov/health-information/liver-disease/autoimmune-hepatitis/symptoms-causes
12. Caafimaadka UF: Jaamacadda Florida Health [Internet]. Gainesville (FL): Jaamacadda Florida Caafimaadka; c2019. Kahortaga muruqa anti-siman: Dulmarka guud [updated 2019 Aug 19; daliishaday 2019 Aug 19]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://ufhealth.org/anti-smooth-muscle-antibody
13. Caafimaadka UF: Jaamacadda Florida Health [Internet]. Gainesville (FL): Jaamacadda Florida Caafimaadka; c2019. Cudurka cagaarshowga ee 'Autoimmune hepatitis': Dulmarka guud [cusboonaysiinta 2019 Agoosto 19; daliishaday 2019 Aug 19]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://ufhealth.org/autoimmune-hepatitis
14. Jaamacadda Rochester Medical Center [Internet]. Rochester (NY): Jaamacadda Rochester Medical Center; c2019. Caafimaadka Encyclopedia: Cudurka Cagaarshowga ee loo yaqaan 'Autoimmune Hepatitis' [oo la soo xigtay 2019 Aug 19]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=85&contentid=P00657
15. Zeman MV, Hirschfield GM. Is-difaaca jirka iyo cudurka beerka: Isticmaalka iyo xadgudubyada. J Gastroenterol ma awoodaa (Internetka). 2010 Apr [daliishaday 2019 Aug 19]; 24 (4): 225–31. Waxaa laga heli karaa: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864616

Macluumaadka ku yaal boggan waa in aan loo isticmaalin beddel daryeel caafimaad oo xirfad leh ama talo. La xiriir bixiye daryeel caafimaad haddii aad su'aalo ka qabtid caafimaadkaaga.