Cholestasis

Cholestasis waa xaalad kasta oo qulqulka qulqulka ee beerka uu gaabis yahay ama xannibmay.

Waxaa jira sababo badan oo cholestasis ah.

Cholestasis dheeri ah waxay ku dhacdaa banaanka beerka. Waxaa sababi kara:

• Burooyinka marinka biibiile
• Fiiq
• Yaraynta marinka xiidmaha (adkeynta)
• Dhagxaanta ku jirta marinka xiidmaha guud
• Qanjirada
• Buroda cudurka sambabka ama 'pseudocyst'
• Cadaadis ku dhaca marinka xiidmaha sababtoo ah culeys ama buro u dhow
• Cudurka 'sclarosing cholangitis' ee aasaasiga ah

Cholestasis intrahepatic waxay ku dhacdaa gudaha beerka. Waxaa sababi kara:

• Cudurka beerka ee khamriga
• Amyloidosis
• Bararka bakteeriyada ee beerka
• Inaad si gaar ah ugu quudato xididka (IV)
• Lymphoma
• Uurka
• Cudurka cirrhosis-ka ee aasaasiga ah
• Kansarka aasaasiga ah ama kansarka beerka
• Cudurka 'sclarosing cholangitis' ee aasaasiga ah
• Sarcoidosis
• Infekshanno halis ah oo ku faafay wareegga dhiigga (sepsis)
• Qaaxada
• Cagaarshowga fayraska

Daawooyinka qaarkood waxay kaloo sababi karaan cholestasis, oo ay ka mid yihiin:

• Antibiyootikada, sida ampicillin iyo penicillins kale
• Steroids dhiska
• Kiniiniyada ka hortagga uurka
• Chlorpromazine
• Cimetidine
• Estradiol
• Imipramine
• Prochlorperazine
• Terbinafine
• Tolbutamide

Calaamadaha waxaa ka mid noqon kara:

• Saxaro midab leh ama midab cad ah
• Kaadi madow
• Awood la'aanta in la dheefshiido cuntooyinka qaarkood
• Cuncun
• Lalabbo ama matagid
• Xanuun ku yaal qaybta midig ee sare ee caloosha
• Maqaarka huruudka ah ama indhaha

Tijaabooyinka dhiigga waxaa laga yaabaa inay muujiyaan inaad sare u kacday bilirubin iyo phosphatase alkaline.

Tijaabinta sawirka waxaa loo isticmaalaa in lagu ogaado xaaladan. Tijaabooyinka waxaa ka mid ah:

• CT iskaanka caloosha
• MRI caloosha
• Endoscopic retrograde cholangiopancreatography (ERCP), ayaa sidoo kale go'aamin kara sababta
• Ultrasound ee caloosha

Sababta asalka u ah cholestasis waa in la daaweeyaa.

Sida ugu wanaagsan ee qofku wax uqabto waxay kuxirantahay cudurka keena xaalada. Dhagxaanta ku jirta marinka xiidmaha guud ayaa badanaa la soo saari karaa. Tani waxay daaweyn kartaa cholestasis.

Xaraarado ayaa loo dhigi karaa si loo furo aagagga xiidmaha xiidmaha ee guud ee loo soo koobo ama u xannibayo kansarrada.

Haddii xaaladdu ay sabab u tahay isticmaalka daawo gaar ah, badanaa way kaa tagaysaa markaad joojiso qaadashada daawadaas.

Dhibaatooyinka waxaa ka mid noqon kara:

• Shuban
• Guuldarrooyinka xubinta ayaa dhici kara haddii sepsisku uu soo baxo
• Si wanaagsan u nuugista dufanka iyo fiitamiinnada isku milma dufanka
• Cuncun daran
• Lafaha daciifka ah (osteomalacia) oo ay ugu wacan tahay haysashada cholestasis waqti aad u dheer

Wac daryeel caafimaad bixiyaha haddii aad leedahay:

• Cuncun aan tagaynin
• Maqaarka huruudka ah ama indhaha
• Calaamadaha kale ee cholestasis

Iska tallaal cagaarshowga A iyo B haddii aad qatar ugu jirto. Ha isticmaalin daawooyinka xididka lagugu shubo oo irbadaha ha la wadaagin.

Xiidmaha 'Intrahepatic cholestasis'; Xinjiraha dheeraadka ah

• Dhagxaanta
• Xameeti
• Xameeti

Eaton JE, Lindor KD. Cholangitis-ka aasaasiga ah. Gudaha: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger iyo Cudurka Mindhicirka iyo Beerka ee Fordtran. 11aad. Philadelphia, PA: Elsevier; 2021: cutubka 91.

Fogel EL, Sherman S. Cudurada xameetida iyo dheecaanka xiidmaha. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 26aad. Philadelphia, PA: Elsevier; 2020: baab 146.

Lidofsky SD. Cagaarshow Gudaha: Feldman M, Friedman LS, Brandt LJ, eds. Cudurka caloosha iyo beerka ee Sleisenger iyo Fordtran. 11aad. Philadelphia, PA: Elsevier; 2021: cutubka 21.