Kalastaroolka - daaweynta daroogada

Jirkaagu wuxuu u baahan yahay kolestarool si uu si sax ah ugu shaqeeyo. Laakiin kolestaroolka dheeraadka ah ee dhiiggaaga ayaa sababa dhigaal ah inay ku ururaan darbiyada gudaha xididdada dhiiggaaga. Dhisiddan waxaa loo yaqaan huurada. Waxay yareysaa xididdada dhiiggaaga waxayna yareyn kartaa ama joojin kartaa socodka dhiigga. Tani waxay u horseedi kartaa wadno qabad, istaroog, iyo cidhiidhi xididdada meelaha kale ee jidhkaaga ah.

Statins waxaa loo maleynayaa inay yihiin daawooyinka ugu fiican ee loo isticmaalo dadka u baahan daawooyinka si ay u yareeyaan kolestaroolkooda.

Hyperlipidemia - daaweynta daroogada; Adkeynta halbowlayaasha - statin

Statins waxay yareyneysaa halista cudurka wadnaha, istaroogga, iyo dhibaatooyinka kale ee la xiriira. Waxay tan ku sameeyaan iyagoo hoos u dhigaya kolestaroolka LDL (xun).

Inta badan waxaad u baahan doontaa inaad qaadato dawadan inta ka dhiman noloshaada. Xaaladaha qaarkood, bedelida qaab nololeedkaaga iyo luminta miisaanka dheeraadka ah ayaa kuu oggolaan kara inaad joojiso qaadashada daawadan.

Haysashada LDL hooseysa iyo wadarta kolestaroolka waxay yareynaysaa halista cudurka wadnaha. Laakiin qof kastaa uma baahna inuu qaato statins si loo yareeyo kolestaroolka.

Bixiyaha daryeelka caafimaadkaaga ayaa go'aan ka gaari doona daaweyntaada iyadoo ku saleysan:

• Wadartaada, HDL (fiican), iyo LDL (xun) heerarka kolestaroolka
• Dadaada
• Taariikhdaada sonkorowga, dhiig karka, ama wadne xanuun
• Dhibaatooyinka kale ee caafimaad ee laga yaabo inay sababaan kolestaroolka sare
• Inaad sigaar cabtid iyo haddii kaleba
• Khatarta cudurka wadnaha
• Jinsiyadaada

Waa inaad qaadataa statins haddii aad 75 jir tahay ama aad ka yar tahay, oo aad taariikh leedahay:

• Dhibaatooyinka wadnaha oo ay ugu wacan tahay halbowlayaasha wadnaha oo cidhiidhya
• Faalig ama TIA (istaroog yar)
• Aneurysm (aortic aneurysm) (ku soo bood halbowlaha weyn ee jirkaaga)
• Ku cidhiidhiga xididdada dhiigga lugahaaga

Haddii aad ka weyn tahay 75, takhtarkaagu wuxuu kuu qori karaa qaddar hoose oo ah statin. Tani waxay kaa caawin kartaa yareynta dhibaatooyinka soo raaca.

Waa inaad qaadataa statins haddii kolestaroolkaaga LDL uu yahay 190 mg / dL ama ka sareeya. Sidoo kale waa inaad qaadataa statins haddii kolestaroolkaaga LDL uu u dhexeeyo 70 iyo 189 mg / dL iyo:

• Waxaad qabtaa sonkorow waxaadna u dhaxeysaa da'da 40 ilaa 75
• Waxaad qabtaa cudurka macaanka iyo halista sare ee cudurada wadnaha
• Waxaad halis sare ugu jirtaa cudurada wadnaha

Adiga iyo daryeel bixiyahaagu waxaad rabi kartaan inaad tixgelisaan statins haddii kolestaroolka LDL uu yahay 70 illaa 189 mg / dL iyo:

• Waxaad qabtaa sonkorow iyo halista dhexdhexaad ee cudurada wadnaha
• Waxaad leedahay khatar dhexdhexaad ah oo ku saabsan cudurka wadnaha

Haddii aad khatar sare ugu jirto cudurka wadnaha isla markaana LDL-ka kolestaroolkaagu uu sarreeyo xitaa haddii la daaweynayo statin, bixiyahaaga ayaa tixgelin kara daawooyinkan marka lagu daro statins:

• Ezetimibe
• PCSK9 xakameeyayaasha, sida alirocumab iyo evolocumab (Repatha)

Dhakhaatiirtu waxay u dejin jireen heer bartilmaameed kolestaroolkaaga LDL. Laakiin hadda diiraddu waxay yareynaysaa halista aad u leedahay dhibaatooyinka ay sababaan cidhiidhiga xididdada dhiigga. Bixiyahaaga ayaa laga yaabaa inuu kormeero heerarka kolestaroolkaaga. Laakiin tijaabooyin badan ayaa marar dhif ah loo baahan yahay.

Adiga iyo daryeel bixiyahaaga ayaa go'aansan doona qiyaasta dawada ee ay tahay inaad qaadato. Haddii aad leedahay arrimo halis ah, waxaad u baahan kartaa inaad qaadato qiyaaso badan. ama ku dar noocyo kale oo daroogo ah. Waxyaabaha uu takhtarkaagu tixgelin doono marka uu dooranayo daaweyntaada waxaa ka mid ah:

• Wadartaada, HDL, iyo LDL heerarka kolestaroolka daaweynta kahor
• Haddii aad qabtid cudurka halbowlayaasha wadnaha (taariikhda angina ama wadno-qabad), taariikhda istaroog, ama xididdada dhiigga ee cidhiidhiga ah ee lugahaaga
• Haddii aad qabtid sonkorow ama sonkorow
• Haddii aad sigaar cabto ama aad qabto dhiig kar

Qaadasho sare waxay keeni kartaa waxyeelo waqti ka dib. Markaa bixiyahaagu sidoo kale wuxuu tixgelin doonaa da'daada iyo arrimaha halista u ah waxyeelooyinka.

• Kalastarool
• Waxyaabaha ku dhaca halbowlaha

Ururka Sonkorowga Mareykanka. Cudurka wadnaha iyo maareynta halista: heerarka daryeelka caafimaadka ee sonkorowga-2020. Daryeelka Sonkorowga. 2018; 43 (Qalabka 1): S111-S134. PMID: 31862753 pubmed.ncbi.nlm.nih.gov/31862753/.

Fox CS, Golden SH, Anderson C, iyo al. Cusboonaysiinta ka hortagga cudurrada wadnaha iyo xididdada ee dadka qaangaarka ah ee qaba nooca sonkorowga 2 ee mellitus iyadoo la tixraacayo caddayntii ugu dambeysay: bayaanka sayniska ee Ururka Wadnaha Mareykanka iyo Ururka Sonkorowga Mareykanka. Wareegga. 2015; 132 (8): 691-718. PMID: 26246173 pubmed.ncbi.nlm.nih.gov/26246173/.

Genest J, Libby P. Dhibaatooyinka Lipoprotein iyo cudurada wadnaha. Gudaha: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Cudurka Wadnaha ee Braunwald: Buugga Buugta Daawada Wadnaha iyo Xididdada. 11aad. Philadelphia, PA: Elsevier; 2019: cutubka 48.

Grundy SM, Stone NJ, Bailey AL, iyo al. 2018 AHA / ACC / AACVPR / AAPA / ABC / ACPM / ADA / AGS / APhA / ASPC / NLA / PCNA Tilmaamaha ku saabsan maareynta kolestaroolka dhiigga: warbixin ku saabsan Kulliyadda Caafimaadka Wadnaha ee Mareykanka / Ururka Wadnaha ee Wadnaha ee Mareykanka ee Tilmaamaha Tababarka Caafimaadka. . J Am Coll Cardiol. 2019; 73 (24): e285-e350. PMID: 30423393 pubmed.ncbi.nlm.nih.gov/30423393/.

Xoogagga Adeegyada Ka-hortagga ee Mareykanka. Bayaanka soo-jeedinta ugu dambeysa: isticmaalka statin ee loogu talagalay kahortagga aasaasiga ah ee cudurrada wadnaha iyo xididdada ee dadka waaweyn: daaweynta kahortagga. www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/statin-use-in-adults-preventive-medication1. La cusbooneysiiyay Noofambar 2016. La helay Maarso 3, 2020.

Soo-koobista talo soo jeedinta Xoogagga Adeegyada Ka-hortagga ee Mareykanka. Isticmaalka Statin ee kahortaga aasaasiga ah ee cudurka wadnaha iyo xididdada ee dadka qaangaarka ah: daaweynta kahortagga. www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication. La cusbooneysiiyay Noofambar 2016. Waxaa la helay Febraayo 24, 2020.

• Angina
• Angioplasty iyo meelaynta adag - halbowlaha carotid
• Angioplasty iyo meelaynta adag - halbowlayaasha durugsan
• Cudurka halbowlaha Carotid
• Qalliinka wadnaha ee Carotid - wuu furan yahay
• Wadne xanuunka
• Wadne qabad
• Qalliinka wadnaha
• Qalliinka wadnaha lagu maro - ugu yaraan qallalan
• Wadne xanuun iyo cunto
• Heerarka kolestaroolka dhiigga oo sarreeya
• Halbowlaha durugsan

• Dayactirka aneurysm-ka caloosha - furan - dheecaan
• Angina - dheecaan
• Angina - waxa aad weydiiso dhakhtarkaaga
• Angioplasty iyo meelaynta adag - carotid artery - dheecaan
• Angioplasty iyo meelaynta adag - halbowlayaasha durugsan - dheecaan
• Dayactirka xididdada dhiigga ee jirka - endovascular - dheecaan
• Atril fibrillation - dheecaan
• Butter, margarine, iyo saliidaha wax lagu kariyo
• Qalliinka wadnaha ee Carotid - dheecaan
• Kalastaroolka - waxa aad weydiiso dhakhtarkaaga
• Xakamaynta dhiig karkaaga
• Dufanka cuntada ayaa la sharaxay
• Tilmaamaha cuntada degdega ah
• Wadne qabad - dheecaan
• Wadne qabad - maxaa la weydiiyaa dhakhtarkaaga
• Waxyaabaha halista u ah cudurka wadnaha
• Wadnaha oo istaaga - maxaa la weydiiyaa dhakhtarkaaga
• Dhiig kar - waxa aad weydiiso dhakhtarkaaga
• Cuntada badda Mediterranean
• Dheecaanka halbowlaha durugsan
• Faalig - dheecaan

• Kalastarool
• Daawooyinka Kalastaroolka
• Kalastaroolka sare ee carruurta iyo dhalinyarada
• LDL: Kalastaroolka "Xun"
• Statins