Cudurka kansarka

Cudurka Kansarka waa koox calaamado ah oo la xiriirta burooyinka kansarka. Kuwani waa burooyinka mindhicirka yar, xiidanka, lifaaqa, iyo tuubbooyinka bronkial ee sambabada.

Cudurka Kansarka waa qaabka astaamaha mararka qaarkood lagu arko dadka qaba burooyinka kansarka. Burooyinkani waa kuwo dhif ah, badanaana tartiib tartiib ah ayey u baxaan. Badi burooyinka kansarka waxaa laga helaa mareenka caloosha iyo sanbabada.

Cudurka Kansarka wuxuu ku dhacaa dad aad u tiro yar oo qaba burooyinka kansarka, ka dib markii buro ku faafto beerka ama sambabka.

Burooyinkaan waxay siidaayaan inbadan oo kamid ah hoormoonka serotonin, iyo sidoo kale dhowr kiimiko kale. Hormoonnada waxay sababaan xididdada dhiigga inay furaan (weynaadaan). Tani waxay keentaa cudurka kansarka.

Cudurka kansarka wuxuu ka kooban yahay afar astaamood oo waaweyn oo ay ka mid yihiin:

• Biyo-baxa (wejiga, qoorta, ama xabadka kore), sida xididdada dhiigga oo ballaadhay ee lagu arko maqaarka (telangiectasias)
• Neefsashada oo ku adkaata, sida xiiqda
• Shuban
• Dhibaatooyinka wadnaha, sida daadinta qalabka wadnaha, garaaca wadnaha oo gaabis ah, cadaadis dhiig oo hooseeya ama sarreeya

Calaamadaha waxaa mararka qaarkood keena jimicsiga jirka, ama cunista ama cabitaanka waxyaabaha sida jiiska buluugga ah, shukulaatada, ama khamriga cas.

Badi burooyinkan waxaa la helaa marka baaritaanada ama habraacyada la sameeyo sababo kale, sida inta lagu guda jiro qalliinka caloosha.

Haddii baaritaan jireed la sameeyo, daryeel caafimaad bixiyaha waxaa laga yaabaa inuu helo astaamo:

• Dhibaatooyinka wadnaha, sida gunuunka
• Cudurka Niacin-yarida (pellagra)

Tijaabooyinka la qaadi karo waxaa ka mid ah:

• 5-Heerarka HIAA ee kaadida
• Tijaabooyinka dhiigga (oo ay ku jiraan serotonin iyo baaritaanka dhiigga chromogranin)
• Baadhitaanka CT iyo MRI ee laabta ama caloosha
• Echocardiogram
• Skaanka loo yaqaan 'Octreotide radiolabeled scan'

Qalliinka looga saarayo burooyinka badanaa waa daaweynta ugu horeysa. Waxay si joogto ah u daaweyn kartaa xaaladda haddii burada gebi ahaanba la saaro.

Haddii buurku ku faafay beerka, daaweyntu waxay ku lug leedahay mid ka mid ah kuwan soo socda:

• Ka qaadida aagagga beerka ee leh unugyada burooyinka
• U dirista (faleebo) daawo si toos ah beerka si loo baabi'iyo burooyinka

Marka burada oo dhan aan la soo saari karin, ka saarista qaybo badan oo buro ah ("debulking") ayaa kaa caawin kara yareynta calaamadaha.

Cirbadaha Octreotide (Sandostatin) ama lanreotide (Somatuline) ayaa la siiyaa dadka qaba burooyinka kansarka ee horumarsan oo aan qalliin looga saari karin.

Dadka qaba cudurka kansarka waa inay ka fogaadaan aalkolada, cunnooyinka waaweyn, iyo cuntooyinka ku badan tyramine (jiiska da'da, avokado, cuntooyin badan oo la farsameeyay), maxaa yeelay waxay kicin karaan calaamadaha

Daawooyinka caadiga ah qaarkood, sida kuwa celiya serotonin reuptake inhibitors (SSRIs), sida paroxetine (Paxil) iyo fluoxetine (Prozac), ayaa calaamadaha uga sii dari kara heerarka sii kordhaya ee serotonin. Si kastaba ha noqotee, HA JOOJIN qaadashada daawooyinkaan illaa bixiyahaagu kuu sheego inaad sidaas sameyso mooyee.

Baro wax badan oo ku saabsan cudurka kansarka isla markaana taageero ka hel:

• Aasaaska kansarka kansarka - www.carcinoid.org/resources/support-groups/directory/
• Neuroendocrine Tumor Research Foundation - netrf.org/for-patients/

Aragtida dadka qaba cudurka kansarka ayaa mararka qaar ka duwan aragtida dadka qaba burooyinka kansarka aan lahayn cilladda.

Saadaashu sidoo kale waxay kuxirantahay goobta burooyinka. Dadka qaba cudurka cilladda, burooyinka ayaa sida caadiga ah ku faafay beerka. Tani waxay hoos u dhigeysaa heerka badbaadada. Dadka qaba cudurka kansarka sidoo kale waxay u badan tahay inay yeeshaan kansar gooni ah (buro labaad oo aasaasi ah) isla waqti isku mid ah. Guud ahaan, saadaashu badanaa waa heer sare.

Dhibaatooyinka cudurka kansarka waxaa ka mid noqon kara:

• Khatarta dhicitaanka iyo dhaawaca oo kordhay (cadaadiska dhiigga oo hooseeya)
• Xiidmaha mindhicirka (oo ka soo baxa buro)
• Dhiigbaxa caloosha
• Wadnaha oo shaqeynaya

Nooca dhimashada ee cudurka kansarka, dhibaatada kansarka, waxaa laga yaabaa inuu ku dhaco waxyeelo dhinaca qalliinka, suuxdinta ama kiimiko ah.

La xiriir daryeel bixiyahaaga si aad ballan u samaysato haddii aad leedahay astaamaha cudurka kansarka.

Daweynta burooyinka waxay yareyneysaa halista cudurka kansarka.

Flush syndrome; Cudurka 'Argentaffinoma syndrome'

• Qaadashada Serotonin

Websaydhka Machadka Kansarka Qaranka. Daaweynta burooyinka caloosha ku dhaca ee caloosha ku dhaca (Dadka waaweyn) (PDQ) - nooca caafimaadka mihnadeed. www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-treatment-pdq. La cusbooneysiiyay Sebtember 16, 2020. Waxaa la helay Oktoobar 14, 2020.

Öberg K. Burooyinka Neuroendocrine iyo cilladaha la xiriira. Gudaha: Melmed S, Auchus, RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Buugga Buugga Endocrinology. 14aad. Philadelphia, PA: Elsevier; 2020: cutubka 45.

Wolin EM, Jensen RT. Burooyinka Neuroendocrine. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 26aad. Philadelphia, PA: Elsevier; 2020: cutubka 219.