Kansarka Endometrial

Kansarka Endometrial waa kansar ka bilaabma endometrium, xuubka ilmagaleenka (ilmo galeenka).

Kansarka Endometrial waa nooca ugu badan ee kansarka xubinta taranka dumarka. Sababta saxda ah ee kansarka endometrial lama yaqaan. Heerka sii kordhaya ee hormoonka estrogen ayaa door ka ciyaari kara. Tani waxay kicineysaa kobcinta dahaarka ilmo-galeenka. Tani waxay u horseedi kartaa kororka aan caadiga ahayn ee endometrium iyo kansarka.

Xaaladaha badankood ee kansarka endometrial waxay dhacaan inta udhaxeysa 60 iyo 70. Xaalado yar ayaa dhici kara kahor da'da 40.

Waxyaabaha soo socda ee la xiriira hormoonnadaada waxay kordhiyaan halista kansarka endometrial:

• Daaweynta beddelka estrogen iyada oo aan la isticmaalin progesterone
• Taariikhda burooyinka endometrial
• Muddooyin aan badnayn
• Waligaa ha uur yeelan
• Cayilka
• Sonkorowga
• Cudurka 'Polycystic ovary syndrome' (PCOS)
• Bilaabidda caadada da'da hore (ka hor da'da 12)
• Bilaabidda caadada dhalmada ka dib da'da 50
• Tamoxifen, waa daawo loo isticmaalo daaweynta kansarka naasaha

Haweenka qaba xaaladahan soosocda sidoo kale waxay umuuqdaan inay qatar sare ugujiraan kansarka endometrial:

• Xiidanka ama kansarka naasaha
• Xameetida
• Dhiig kar

Calaamadaha kansarka endometrial waxaa ka mid ah:

• Dhiigbax aan caadi ahayn oo ka yimaada xubinta taranka dumarka, ay kujirto dhiigbax udhaxeeya caadada ama dhibic / dhiig baxa caadada ka dib
• Aad iyo aad u dheer, culus, ama dhacdooyin soo noqnoqda oo ah dhiig bax siilka ka dib da'da 40
• Xanuun caloosha hoose ama casiraad miskaha ah

Inta lagu jiro marxaladaha hore ee cudurka, baaritaanka miskaha badanaa waa caadi.

• Marxaladaha horumarsan, waxaa jiri kara isbedello ku yimaada cabirka, qaabka, ama dareenka makaanka ama dhismooyinka ku xeeran.
• Pap smear (wuxuu kicin karaa shaki ku saabsan kansarka endometrial, laakiin ma baarto)

Iyada oo ku saleysan astaamahaaga iyo natiijooyinka kale, baaritaanno kale ayaa loo baahan karaa. Qaarkood waxaa lagu sameyn karaa xafiiska bixiyaha daryeelka caafimaadkaaga. Kuwa kale waxaa lagu sameyn karaa isbitaal ama xarun qalliin:

• Endometrial biopsy: Iyadoo la isticmaalayo kateetar yar ama dhuuban (tubbo), nudaha ayaa laga soo qaadaa xuubka ilmagaleenka (endometrium). Unugyada waxaa lagu baarayaa mikroskoob si loo arko haddii ay u muuqdaan kuwo aan caadi ahayn ama kansar qaba.
• Hysteroscopy: Qalab dhuuban oo u eg teleskop-ka ayaa la dhex gelinayaa xubinta taranka haweenka iyo furitaanka makaanka afkiisa. Waxay u oggolaaneysaa adeeg bixiyaha inuu fiiriyo gudaha ilmo-galeenka.
• Ultrasound: Mawjadaha dhawaaqa waxaa loo isticmaalaa in lagu sameeyo sawir ah xubnaha miskaha. Ultrasound waxaa lagu samayn karaa si caadi ah ama siil. Ultrasound ayaa go'aamin kara haddii dahaarka ilmo-galeenka u muuqdo mid aan caadi ahayn ama dhumuc weyn.
• Sonohysterography: Dheecaanka waxaa la geliyaa minka iyada oo la marinayo tuubo khafiif ah, halka sawirada ultrasoundka siilka laga sameeyay ilmo galeenka. Nidaamkan waxaa loo samayn karaa si loo ogaado jiritaanka culeys aan caadi ahayn oo ku dhaca makaanka ilmo-galeenka oo noqon kara calaamado kansar.
• Sawir-celinta 'Magnetic resonance imaging' (MRI): Imtixaankan imaging, magnets awood badan ayaa loo isticmaalaa in lagu abuuro sawirrada xubnaha gudaha.

Haddii kansar la helo, tijaabooyin sawir ayaa laga qaadi karaa si loo ogaado haddii kansarku ku fiday qaybaha kale ee jirka. Tan waxaa lagu magacaabaa staging.

Heerarka kansarka endometrial waa:

• Marxaladda 1: Kansarku wuxuu ku jiraa ilmo galeenka oo keliya.
• Marxaladda 2: Kansarku wuxuu ku jiraa ilmo galeenka iyo makaanka afkiisa.
• Marxaladda 3: Kansarku wuxuu ku faafay meel ka baxsan ilmo-galeenka, laakiin kama dhaafin aagga miskaha dhabta ah. Kansarku wuxuu ku lug yeelan karaa qanjidhada qanjirada miskaha ama agagaarka aorta (halbowlaha weyn ee caloosha).
• Marxaladda 4: Kansarku wuxuu ku faafay gudaha gudaha mindhicirka, kaadi haysta, caloosha, ama xubnaha kale.

Kansarka sidoo kale waxaa lagu sharaxay inuu yahay fasalka 1, 2, ama 3. Fasalka 1 waa kan ugu dagaalka yar, darajada 3na waa tan ugu dagaalka badan. Gardarro micnaheedu waa in kansarku si dhakhso leh u fido una fido.

Fursadaha daaweynta waxaa ka mid ah:

• Qalliinka
• Daaweynta shucaaca
• Dawaynta kimikalka

Qalliin looga soo saarayo makaanka (hysterectomy) waxaa laga yaabaa in lagu sameeyo dumarka qaba kansarka marxaladda hore 1. Dhakhtarka ayaa sidoo kale laga yaabaa inuu soo saaro tuubooyinka iyo ugxansidaha.

Qalliinka oo lagu daro daaweynta shucaaca waa ikhtiyaar daaweyn kale. Waxaa badanaa loo isticmaalaa dumarka leh:

• Cudurka heerka 1aad ee leh fursad sare oo uu ku soo laabto, wuxuu ku faafay qanjidhada qanjidhada, ama waa fasal 2 ama 3
• Cudurka 2aad

Daaweynta kiimikada ama daaweynta hoormoonka xaaladaha qaarkood ayaa laga fiirsan karaa, badanaa badiyaa kuwa qaba cudurka 3 iyo 4.

Waad yareyn kartaa diiqada jirrada adoo ku biiraya kooxda taageerta kansarka. La wadaagida dadka kale ee leh khibradaha guud iyo dhibaatooyinka ayaa kaa caawin kara inaadan kali dareemin.

Kansarka Endometrial waxaa badanaa lagu ogaadaa marxaladda hore.

Haddii kansarku uusan faafin, 95% haweenku waxay nool yihiin 5 sano kadib. Haddii kansarku ku fido xubnaha fog, qiyaastii 25% haweenku weli way nool yihiin 5 sano ka dib.

Dhibaatooyinka waxaa ka mid noqon kara mid ka mid ah kuwan soo socda:

• Dhiigyaraan dhiig la'aan awgeed (baaritaanka kahor)
• Dalool (dalool) ilmo-galeenka, oo dhici kara inta lagu jiro D iyo C ama biopsy endometrial
• Dhibaatooyinka ka yimaada qalliinka, shucaaca, iyo daaweynta kiimikada

Ballan wac wac bixiyahaaga haddii aad leedahay mid ka mid ah kuwan soo socda:

• Dhiigbax kasta ama dhibco ah oo dhaca ka dib bilawga caadada
• Dhiigbax ama dhibco ka dib galmada ama dheecaanka ka dib
• Dhiigbaxu wuxuu soconayaa in ka badan 7 maalmood
• Wareega caadada ee aan caadiga ahayn ee dhaca laba jeer bishiiba
• Dheecaan cusub kadib dhalmo dayska ayaa bilaabmay
• Xanuun miskaha ama casiraada oo aan ka bixinaynin

Ma jiro baaritaan baaritaan oo wax ku ool ah oo loogu talagalay kansarka endometrial (makaanka).

Haweenka leh sababaha halista u ah kansarka endometrial-ka waa inuu si dhow ula socdaa dhakhaatiirtooda. Tan waxaa ku jira dumarka qaadanaya:

• Daaweynta beddelka estrogen iyada oo aan lahayn daaweynta progesterone
• Tamoxifen in ka badan 2 sano

Baadhitaanada miskaha oo isdaba joog ah, Pap smears, ultrasounds siilka, iyo biopsy endometrial ayaa laga yaabaa in lagu tixgeliyo xaaladaha qaarkood.

Khatarta kansarka endometrial-ka waxaa hoos u dhigay:

• Joogitaanka miisaan caadi ah
• Isticmaalka kaniiniyada ka hortagga uurka muddo ka badan hal sano

Endenrial adenocarcinoma; Uterine adenocarcinoma; Kansarka kaadi mareenka; Adenocarcinoma - endometrium; Adenocarcinoma - ilmo-galeenka; Kansarka - minka; Kansarka - endometrial; Kansarka qanjirka 'Uterine corpus'

• Hysterectomy - dheecaan caloosha ah
• Hysterectomy - laparoscopic - dheecaan
• Qalitaanka xubinta taranka dumarka - dheecaanka siilka
• Shucaaca miskaha - dheecaan

• Laparoscopy-ga miskaha
• Jirka anatomi ee taranka dumarka
• D iyo C
• Cad ka-qaadista Endometrial
• Qalitaanka xubinta taranka dumarka
• Ilma-galeenka
• Kansarka Endometrial

Armstrong DK. Kansarka dumarka. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 26aad. Philadelphia, PA: Elsevier; 2020: cutubka 189.

Boggess JF, Kilgore JE, Tran A-Q. Kansarka kaadi mareenka. Gudaha: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6aad ed. Philadelphia, PA: Elsevier; 2020: baab 85.

Morice P, Leary A, Creutzberg C, Abu-Rustum N, Darai E. Kansarka Endometrial. Lancet. 2016; 387 (10023): 1094-1108. PMID: 26354523 pubmed.ncbi.nlm.nih.gov/26354523/.

Websaydhka Machadka Kansarka Qaranka. Daaweynta daaweynta kansarka Endometrial (PDQ) - nooca xirfad-yaqaan caafimaad. www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq. La cusbooneysiiyay Diseembar 17, 2019. Waxaa la helay 24-kii Maarso, 2020.

Shabakada Shabakada Shabakada Kansarka oo dhameystiran. Tilmaamaha tababarka caafimaadka ee NCCN ee kansarka (tilmaamaha NCCN): neoplasms-ka ilmo-galeenka. Nooca 1.2020. www.nccn.org/professionals/physician_gls/pdf/uterine.pdf. La cusbooneysiiyay Maarso 6, 2020. Waxaa la helay 24, 2020.