Dysplasia afka ilmo galeenka

Dysplasia afka ilmo-galeenka waxaa loola jeedaa isbeddelo aan caadi ahayn oo ku dhaca unugyada dusha sare ilmo galeenka. Afka ilmagaleenku waa qaybta hoose ee makaanka (minka) oo ka furma dusha sare siilka.

Isbedelada ma aha kansar laakiin waxay u horseedi karaan kansarka makaanka afkiisa haddii aan la daaweyn.

Dysplasia afka ilmo-galeenka ayaa ku dhici kara da 'kasta. Si kastaba ha noqotee, dabagal iyo daaweyn waxay kuxirantahay da'daada. Dysplasia afka ilmo galeenka waxaa inta badan sababa papillomavirus-ka aadanaha (HPV). HPV waa fayras caan ah oo ku faafa galmada. Waxaa jira noocyo badan oo HPV ah. Noocyada qaarkood waxay u horseedaan dysplasia afka ilmo-galeenka ama kansar. Noocyada kale ee HPV waxay sababi karaan burooyinka xubnaha taranka.

Waxyaabaha soo socdaa waxay kordhin karaan halista aad ugu jirto dysplasia xubinta taranka dumarka:

• Sameynta galmo kahor da'da 18
• Inaad yeelato ilmo aad u yar
• Isagoo la yeeshay lamaanayaal badan oo galmo ah
• Inaad leedahay cuduro kale, sida qaaxada ama HIV
• Adeegsiga daawooyinka xakameynaya habka difaaca jirka
• Sigaar cabid
• Taariikhda hooyada ee soo-gaadhista DES (diethylstilbestrol)

Inta badan, ma jiraan wax calaamado ah.

Bixiyahaaga daryeelka caafimaadka ayaa sameyn doona baaritaanka miskaha si loo hubiyo dysplasia xubinta taranka dumarka. Imtixaanka ugu horeeya badanaa waa baaritaanka Pap test iyo baaritaanka jiritaanka HPV.

Dysplasia afka ilmo galeenka oo lagu arko baaritaanka Pap waxaa loo yaqaan 'squamous intraepithelial lesion' (SIL). Warbixinta baaritaanka Pap test, isbeddeladan waxaa lagu tilmaami doonaa:

• Darajada-hoose (LSIL)
• Fasalka-sare (HSIL)
• Suurtagal inay tahay kansar (malignant)
• Unugyada qanjirka 'atypical glandular' (AGC)
• Unugyada squamous atypical (ASC)

Waxaad u baahan doontaa baaritaanno dheeri ah haddii baaritaanka Pap ay muujiyaan unugyo aan caadi ahayn ama dysplasia afka ilmo-galeenka. Haddii isbeddelada ay khafiif ahaayeen, baaritaanada la-socoshada Pap ayaa laga yaabaa in loo baahdo oo keliya.

Bixiyaha ayaa laga yaabaa inuu sameeyo cad ka-qaadis si loo xaqiijiyo xaaladda. Tan waxaa lagu samayn karaa iyadoo la isticmaalayo colposcopy. Meel kasta oo walaac laga muujinayaa waa la soo koobi doonaa. Biopsiyada waa kuwo aad u yar dumarka badidood waxay dareemaan uun cariiri yar.

Dysplasia oo lagu arko dheecaanka biopsy ee afka ilmo galeenka waxaa lagu magacaabaa afka ilmagaleenka intraepithelial neoplasia (CIN). Waxaa loo qaybiyay 3 qaybood:

• CIN I - dysplasia fudud
• CIN II - dhexdhexaad ama calaamadeys dysplasia
• CIN III - dysplasia daran oo ku dhacda kansarka

Noocyada HPV qaarkood ayaa lagu yaqaan inay sababaan kansarka xubinta taranka dumarka. Baadhitaanka DNA ee HPV ayaa lagu garan karaa noocyada halista sare leh ee HPV ee ku xidhan kansarkan. Tijaabadani waa la samayn karaa:

• Sida tijaabada baaritaanka ee dumarka ka weyn 30 jir
• Haweenka da 'kasta oo leh waxoogaa aan caadi ahayn natiijada baaritaanka Pap test

Daaweyntu waxay kuxirantahay heerka dysplasia. Cudurka 'Dysplasia' oo fudud (LSIL ama CIN I) ayaa laga yaabaa inuu baxo daaweyn la'aan.

• Waxaad u baahan kartaa oo keliya inaad si taxaddar leh ula socotid bixiyahaaga oo ku celceliyo baaritaanka Pap 6 ilaa 12 bilood kasta.
• Haddii isbeddellada aysan ka bixin ama ka sii darin, daaweyn ayaa loo baahan yahay.

Daaweynta dysplasia-ilaa-daran ama dysplasia khafiif ah oo aan dhamaanayn waxaa ka mid ah:

• Qalliinka Cryosurgery si loo joojiyo unugyada aan caadiga ahayn
• Daaweynta laser-ka, oo u isticmaasha iftiinka si ay u gubto unugyada aan caadiga ahayn
• LEEP (nidaamka loo yaqaan 'loop elektaroolista qalliinka'), oo isticmaala koronto si looga saaro unugyada aan caadiga ahayn
• Qalliin si looga saaro unug aan caadi ahayn (cone biopsy)
• Qalitaanka taranka dumarka (xaalado dhif ah)

Haddii uu kugu dhacay dysplasia, waxaad u baahan doontaa in lagu celiyo baaritaannada 12-kii biloodba mar ama sida uu ku taliyo bixiyahaagu.

Hubso inaad hesho tallaalka HPV markii lagu siiyo. Tallaalkan wuxuu ka hortagaa kansarro badan oo ku dhaca makaanka afkiisa.

Cilad-baarista hore iyo daaweynta degdegga ah waxay daaweynayaan kiisaska badankood ee dysplasia afka ilmo-galeenka. Si kastaba ha noqotee, xaaladdu way soo noqon kartaa.

Daaweyn la'aan, dysplasia daran ee xubinta taranka dumarka waxay isu beddeli kartaa kansarka xubinta taranka dumarka.

Wac daryeel bixiyahaaga haddii da'daadu tahay 21 ama ka weyn oo aadan waligaa soo marin baaritaanka miskaha iyo baaritaanka Pap.

Weydii takhtarkaaga tallaalka HPV. Gabdhaha la siiyo tallaalkan ka hor intaanay noqon kuwa firfircoon galmada waxay yareeyaan fursadda inay ku dhacaan kansarka xubinta taranka dumarka.

Waad yareyn kartaa halista aad ugu jirtid dysplasia xubinta taranka adiga oo qaadaya talaabooyinka soo socda:

• Iska tallaal HPV inta u dhexeysa 9 ilaa 45 sano.
• Sigaar ha cabin. Sigaar cabiddu waxay kordhisaa halista aad ugu jirtid dysplasia daran iyo kansar.
• Ha sameynin galmo ilaa aad 18 ama ka weyn tahay.
• Samee galmo aamin ah. Isticmaal kondhom.
• Ku celceli hal xaas Tan macnaheedu waxa weeye inaad haysato hal lammaane oo galmo ah markiiba.

Afka ilmo galeenka neoplasia - dysplasia; CIN - dysplasia; Isbeddelada mudnaanta leh ee makaanka afkiisa - dysplasia; Kansarka afka ilmo-galeenka - dysplasia; Dhaawaca 'intraepithelial lesion' - dysplasia; LSIL - dysplasia; HSIL - dysplasia; Dysplasia-darajo hoose; Heerka sare ee 'dysplasia'; Carcinoma in situ - dysplasia; CIS - dysplasia; ASCUS - dysplasia; Unugyada qanjirka 'atypical glandular' - dysplasia; AGUS - dysplasia; Unugyada squamous atypical - dysplasia; Pap smear - dysplasia; HPV - dysplasia; Fayraska papilloma ee aadanaha - dysplasia; Ilmo galeenka - dysplasia; Colposcopy - dysplasia

• Jirka anatomi ee taranka dumarka
• Neoplasia afka ilmo-galeenka
• Ilma-galeenka
• Dysplasia ilmo galeenka - taxane

Kuleejka Dhakhaatiirta Haweenka iyo Dhakhaatiirta Haweenka ee Mareykanka. Layli Bulletin No 168: baaritaanka kansarka xubinta taranka dumarka iyo kahortaga. Cudurka Gynecol. 2016; 128 (4): e111-e130. PMID: 27661651 pubmed.ncbi.nlm.nih.gov/27661651/.

Kuleejka Dhakhaatiirta Haweenka iyo Dhakhaatiirta Haweenka ee Mareykanka. Layli Bulletin No 140: maareynta natiijooyinka baaritaanka kansarka xubinta taranka dumarka ee aan caadiga ahayn iyo horudhaca kansarka ilmo galeenka. Cudurka Gynecol. 2013; 122 (6): 1338-1367. PMID: 24264713 pubmed.ncbi.nlm.nih.gov/24264713/.

Armstrong DK. Kansarka dumarka. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 26aad. Philadelphia, PA: Elsevier; 2020: cutubka 189.

Freedman MS, Hunter P, Ault K, Kroger A. Gudiga La-talinta ee Ku-Dhaqanka Tallaalada ayaa ku taliyay jadwalka tallaalka ee dadka waaweyn ee jira 19 sano ama ka weyn - Mareykanka, 2020. MMWR Morb Dhimasho Wkly Rep. 2020; 69 (5): 133-135. PMID: 32027627 pubmed.ncbi.nlm.nih.gov/32027627/.

Hackers NF. Dysplasia ilmo galeenka iyo kansarka. Gudaha: Hacker NF, Gambone JC, Hobel CJ, eds. Waxyaabaha Aasaasiga u ah Dhalmada iyo Haweenka ee Hacker & Moore. 6aad ed. Philadelphia, PA: Elsevier; 2016: cutubka 38.

Kooxda Shaqada Khabiirka ah ee Talaalka, Gudiga Daryeelka Caafimaadka dhalinyarada. Fikradda Guddiga No. 704: tallaalka papillomavirus ee bini'aadamka. Cudurka Gynecol. 2017; 129 (6): e173-e178. PMID: 28346275 pubmed.ncbi.nlm.nih.gov/28346275/.

Robinson CL, Bernstein H, Poehling K, Romero JR, Szilagyi P. Guddiga La-talinta ee Ku-Dhaqanka Tallaalada Waxaa lagu taliyey jadwalka tallaalka ee carruurta iyo dhallinyarada da'doodu tahay 18 sano ama ka yar - Mareykanka, 2020. MMWR Morb Dhimasho Wkly Rep. 2020; 69 (5): 130-132. PMID: 32027628 pubmed.ncbi.nlm.nih.gov/32027628/.

MP Salcedo, Baker ES, Schmeler KM. Neoplasia Intraepithelial ee xubinta taranka hoose (makaanka afkiisa, siilka, xubinta taranka): etiology, baaritaanka, ogaanshaha, maamulka Gudaha: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Cilmiga Haweenka oo dhameystiran. 7aad ed. Philadelphia, PA: Elsevier; 2017: cutubka 28.

Saslow D, Solomon D, Lawson HW, et al; Guddiga Tilmaamaha Kansarka Ilmo-galeenka ee ACS-ASCCP-ASCP. Bulshada Cancer American, American Society for Colposcopy and Cervical Pathology, iyo American Society for Clinical Pathology baaritaanka tilmaamaha kahortaga iyo ogaanshaha hore ee kansarka xubinta taranka dumarka. CA Kansarka J Clin. 2012; 62 (3): 147-172. PMID: 22422631 pubmed.ncbi.nlm.nih.gov/22422631/.

Xoogagga Adeegyada Ka-hortagga ee Mareykanka, Curry SJ, Krist AH, Owens DK, iyo al. Baadhitaanka kansarka xubinta taranka dumarka: Bayaanka talobixinta ee Kooxda Kahortagga Adeegyada ee Mareykanka. JAMA. 2018; 320 (7): 674-686. PMID: 30140884 pubmed.ncbi.nlm.nih.gov/30140884/.