ACTH baaritaanka dhiigga

Imtixaanka ACTH wuxuu cabiraa heerka hormoonka adrenocorticotropic (ACTH) ee dhiiga kujira. ACTH waa hormoon laga sii daayo qanjirka 'pituitary gland' ee maskaxda.

Sambal dhiig ayaa loo baahan yahay.

Dhakhtarkaaga ayaa u badan inuu kaa codsado in lagugu sameeyo baaritaanka subaxa hore. Tani waa muhiim, maxaa yeelay heerka cortisol wuu kala duwan yahay maalintii oo dhan.

Sidoo kale waxaa laguu sheegi karaa inaad joojiso qaadashada daawooyinka saameyn ku yeelan kara natiijooyinka baaritaanka. Daawooyinkaan waxaa ka mid ah daawada loo yaqaan 'glucocorticoids' sida 'prednisone', 'hydrocortisone', ama 'dexamethasone'. (Ha joojin daawooyinkan illaa bixiyahaagu ku faray mooyee)

Marka irbadda la geliyo si dhiig loo qaado, dadka qaar waxay dareemaan xanuun dhexdhexaad ah. Qaar kale waxay dareemaan oo keliya dharbaaxo ama xaniin. Intaas ka dib, waxaa laga yaabaa in xoogaa wax garaaco ama nabarro yar yeeshaan. Tani dhawaan way tagi doontaa.

Shaqada ugu weyn ee ACTH waa in la xakameeyo glucocorticoid (steroid) hormoonka cortisol. Cortisol waxaa lagu sii daayaa qanjirka 'adrenal gland'. Waxay nidaamisaa cadaadiska dhiigga, sonkorta dhiigga, habka difaaca jirka iyo ka jawaab celinta walaaca.

Tijaabadani waxay kaa caawin kartaa helitaanka sababaha dhibaatooyinka hormoonnada qaarkood.

Qiimaha caadiga ah ee sambal dhiig oo la qaado subaxa hore waa 9 ilaa 52 pg / mL (2 ilaa 11 pmol / L).

Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabin karaan tijaabooyin kala duwan. Kala hadal dhakhtarkaaga macnaha natiijooyinka baaritaankaaga gaarka ah.

Heer ka-caadi caadi ah ACTH ayaa tilmaami kara:

• Qanjirada 'Adrenal' oo aan soo saarin cortisol ku filan (cudurka Addison)
• Qanjirada 'Adrenal' oo aan soo saarin hormoonno ku filan (congenital adrenal hyperplasia)
• Mid ama in kabadan qanjidhada endocrine waa kuwo kacsan ama sameeyay buro (noocyo badan oo endocrine neoplasia ah I)
• Pituitary wuxuu sameeyaa ACTH badan (Cushing disease), oo badanaa keena burooyinka aan kansarka lahayn ee qanjirka 'pituitary gland'
• Nooc naadir ah oo ah buro (sambabada, tayroodh, ama xammeetida) oo aad u badan sameeya ACTH (ectopic Cushing syndrome)

Heer ka hooseeya-caadiga ah ee ACTH ayaa tilmaami kara:

• Daawooyinka Glucocorticoid waxay xakameynayaan wax soo saarka ACTH (inta badan)
• Qanjirka 'pituitary gland' oo aan soo saarin hormoonno ku filan, sida ACTH (hypopituitarism)
• Buro ka mid ah qanjidhada adrenal ee soosaarta cortisol aad u tiro badan

Khatar yar ayaa ku jirta in dhiigga lagaa qaado. Xididdada iyo halbowlayaasha waxay ku kala duwan yihiin cabirka qof ilaa qof kale iyo dhinac jirka ah ilaa dhinac kale. Qaadashada dhiigga dadka qaar way ka dhib badnaan kartaa kuwa kale.

Khataraha kale ee la xiriira dhiig qaadashada way yar yihiin laakiin waxaa ka mid noqon kara:

• Dhiigbax xad dhaaf ah
• Miyir beelid ama dareemid madax-wareer
• Daloollo badan si loo helo xididdada
• Hematoma (dhiig ku ururaya maqaarka hoostiisa)
• Infekshan (halis yar mar kasta oo maqaarku jabo)

Serum adrenocorticotropic hormone; Hormarka Adrenocorticotropic; Xasaasiyad sare leh ACTH

• Qanjirada 'Endocrine'

Chernecky CC, Berger BJ. Hormarka Adrenocorticotropic (ACTH, corticotropin) - serum. Gudaha: Chernecky CC, Berger BJ, eds. Tijaabooyinka Shaybaarka iyo Nidaamyada Baadhista. 6aad ed. St Louis, MO: Elsevier Saunders; 2013: 107.

Melmed S, Kleinberg D. Cudurka Pituitary iyo burooyinka. Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Buugga Buugga Endocrinology. 13aad. Philadelphia, PA: Elsevier; 2016: cutubka 9.

Stewart PM, Newell-Price JDC. Kiliyaha adrenal. Gudaha: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Buugga Buugga Endocrinology. 13aad. Philadelphia, PA: Elsevier; 2016: cutubka 15.