Imtixaanka DHEA-sulfate

DHEA waxay u taagan tahay dehydroepiandrosterone. Waa hormoon daciif ah oo lab ah (androgen) oo ay soo saaraan qanjidhada adrenal ee ragga iyo dumarkaba. Baaritaanka DHEA-sulfate wuxuu cabiraa qadarka DHEA-sulfate ee dhiiga kujira.

Sambal dhiig ayaa loo baahan yahay.

Diyaargarow gaar ah looma baahna. Si kastaba ha noqotee, u sheeg daryeel bixiyahaaga caafimaadka haddii aad qaadanayso fiitamiinno ama dheeri ah oo ay ku jiraan DHEA ama DHEA-sulfate.

Marka irbadda la geliyo si dhiig loo qaado, dadka qaar waxay dareemaan xanuun dhexdhexaad ah. Kuwa kale waxay dareemaan oo keliya dharbaaxo ama xaniinyo. Intaas ka dib, waxaa laga yaabaa inay xoogaa wax garaacaan ama nabar yar. Tani dhawaan way tagi doontaa.

Tijaabadan waxaa loo sameeyay si loo hubiyo shaqada labada qanjirro adrenal. Mid ka mid ah qanjirradan ayaa fadhiya meel ka sarreysa kilyaha kasta. Iyagu waa mid ka mid ah ilaha ugu waaweyn ee asrogrogyada dumarka.

In kasta oo DHEA-sulfate uu yahay hormoonka ugu badan jirka, shaqadiisa saxda ah wali lama oga.

• Ragga, saameynta hoormoonka ragga lagama yaabo inay muhiim tahay haddii heerka testosterone uu caadi yahay.
• Haweenka, DHEA waxay gacan ka geysataa libido caadi ah iyo qanacsanaanta galmada.
• DHEA waxay sidoo kale saameyn ku yeelan kartaa nidaamka difaaca jirka.

Tijaabada 'DHEA-sulfate' waxaa badanaa lagu sameeyaa dumarka muujiya astaamaha inay leeyihiin hoormoonno badan oo lab ah. Calaamadahaas qaarkood waa isbeddelada jirka labka ah, koritaanka timaha oo saaid ah, maqaarka dufanka leh, finanka, xilliyada aan caadiga ahayn, ama dhibaatooyinka uurka.

Waxaa sidoo kale laga yaabaa in lagu sameeyo haweenka ka walwalsan libido hooseysa ama qanacsanaanta galmada oo hoos u dhacda kuwaas oo qaba xanuunada pituitary ama adrenal gland.

Tijaabada waxaa sidoo kale lagu sameeyaa carruurta bislaata goor hore (qaangaarka precocious).

Heerarka caadiga ah ee dhiigga ee DHEA-sulfate way ku kala duwanaan karaan jinsiga iyo da'da.

Caadooyinka caadiga ah ee dumarka waa:

• Da'da 18 illaa 19: 145 illaa 395 mikrogram halkii deciliter (µg / dL) ama 3.92 ilaa 10.66 micromoles halkii litir (µmol / L)
• Da'da 20 illaa 29: 65 illaa 380 µg / dL ama 1.75 ilaa 10.26 olmol / L
• Da'da 30 illaa 39: 45 illaa 270 µg / dL ama 1.22 illaa 7.29 olmol / L
• Da'da 40 ilaa 49: 32 illaa 240 µg / dL ama 0.86 ilaa 6.48 olmol / L
• Da’da 50 ilaa 59: 26 ilaa 200 µg / dL ama 0.70 ilaa 5.40 µmol / L
• Da’da 60 ilaa 69: 13 ilaa 130 µg / dL ama 0.35 ilaa 3.51 olmol / L
• Da'da 69 iyo ka weyn: 17 ilaa 90 µg / dL ama 0.46 ilaa 2.43 olmol / L

Heerarka caadiga ah ee caadiga ah ee ragga waa:

• Da'da 18 illaa 19: 108 ilaa 441 µg / dL ama 2.92 ilaa 11.91 olmol / L
• Da'da 20 ilaa 29: 280 ilaa 640 µg / dL ama 7.56 ilaa 17.28 olmol / L
• Da'da 30 illaa 39: 120 illaa 520 µg / dL ama 3.24 ilaa 14.04 olmol / L
• Da'da 40 ilaa 49: 95 ilaa 530 µg / dL ama 2.56 ilaa 14.31 olmol / L
• Da'da 50 illaa 59: 70 illaa 310 µg / dL ama 1.89 ilaa 8.37 olmol / L
• Da'da 60 illaa 69: 42 illaa 290 µg / dL ama 1.13 illaa 7.83 olmol / L
• Da'da 69 iyo ka weyn: 28 illaa 175 µg / dL ama 0.76 ilaa 4.72 olmol / L

Heerarka qiimaha caadiga ahi way ku kala duwanaan karaan shaybaarada kala duwan. Shaybaarada qaarkood waxay isticmaalaan cabbiro kala duwan ama waxay tijaabiyaan noocyo kala duwan. Kala hadal bixiyahaaga daryeelka caafimaadka macnaha natiijooyinkaaga gaarka ah ee baaritaanka.

Kordhinta DHEA-sulfate waxaa laga yaabaa inay sabab u tahay:

• Cillad hidde-wadareed caadi ah oo loo yaqaan 'congenital adrenal hyperplasia'.
• Buro ka mid ah qanjidhada 'adrenal gland', oo noqon kara mid aan fiicnayn ama noqon kara kansar.
• Dhibaato guud oo ku dhacda haweenka da'doodu ka yar tahay 50, oo loo yaqaan 'polycystic ovary syndrome'.
• Isbeddelka jirka ee gabadha qaangaadhnimada oo dhacaya wax ka horreeya sidii caadiga ahayd.

Hoos u dhac ku yimaada DHEA sulfate waxaa laga yaabaa inay sabab u tahay:

• Ciladaha qanjirka 'adrenal gland' ee soo saara qaddar ka hooseeya inta caadiga ah ee hormoonnada adrenal, oo ay ku jiraan adrenal la'aanta iyo cudurka Addison
• Qanjirka 'pituitary gland' oo aan soo saarin qaddarka caadiga ah ee hormoonnadiisa (hypopituitarism)
• Qaadashada daawooyinka 'glucocorticoid'

Heerarka DHEA waxay caadi ahaan hoos u dhacaan da'da ragga iyo dumarka labadaba. Ma jiro caddayn la isku halleyn karo oo ah qaadashada daawooyinka DHEA waxay ka hortageysaa xaaladaha la xiriira da'da.

Khatar yar ayaa ku jirta in dhiigaaga lagaa qaado. Xididdada iyo halbowlayaasha waxay ku kala duwan yihiin cabirka qof ilaa qof kale iyo dhinac jirka ah dhinaca kale. Helitaanka tijaabada dhiigga ee dadka qaarkiis way ka dhib badan tahay kuwa kale.

Khataraha kale ee la xiriira dhiig qaadashada waa yar yihiin, laakiin waxaa ka mid noqon kara:

• Dhiigbax xad dhaaf ah
• Miyir beelid ama dareemid madax-wareer
• Daloollo badan si loo helo xididdada
• Hematoma (dhiigbax maqaarka hoostiisa)
• Infekshan (halis yar mar kasta oo maqaarku jabo)

Serum DHEA-sulfate; Tijaabada Dehydroepiandrosterone-sulfate; DHEA-sulfate - serum

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Nakamoto J. Baaritaanka Endocrine. Gudaha: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Dadka waaweyn iyo carruurta. 7aad ed. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 154.

Nerenz RD, Jungheim E, Gronowksi AM. Endocrinology taranka iyo cilladaha la xiriira. Gudaha: Rifai N, ed. Tietz Textbook ee Kiimikada Caafimaadka iyo Cilad-baarista Molecular. 6aad ed. St Louis, MO: Elsevier; 2018: cutubka 68.

Rosenfield RL, Barnes RB, Ehrmann DA. Hyperandrogenism, hirsutism, iyo polycystic ugxan syndrome. Gudaha: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Dadka waaweyn iyo carruurta. 7aad ed. Philadelphia, PA: Elsevier Saunders; 2016: cutubka 133.

van den Beld AW, Lamberts SWJ. Endocrinology iyo gabowga. Gudaha: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Buugga Buugga Endocrinology. 14aad. Philadelphia, PA: Elsevier; 2020: cutubka 28.