Qoraa: William Ramirez
Taariikhda Abuurista: 15 Setembar 2021
Taariikhda Cusboonaysiinta: 1 Abriil 2025
Anonim
Vitamin K and hemostasis
Dareemoleyad: Vitamin K and hemostasis

Qanacsan

Faytamiin K waa fiitamiin laga helo khudradda cagaaran ee caleenta ah, broccoli, iyo Brussels sprouts. Magaca fitamiin K wuxuu ka yimid erayga Jarmalka "Koagulationsvitamin."

Noocyo badan oo fiitamiin K ah ayaa adduunka oo dhan looga adeegsadaa dawo ahaan. Faytamiin K1 (phytonadione) iyo fitamiin K2 (menaquinone) ayaa laga heli karaa Waqooyiga Ameerika. Faytamiin K1 guud ahaan waa nooca la doorbido ee fitamiin K maxaa yeelay waa sun yar yahay wuxuuna u shaqeeyaa si dhakhso leh xaaladaha qaarkood.

Faytamiin K ayaa badanaa loo isticmaalaa dhibaatooyinka xinjirowga dhiigga ama dib u celinta saameynta khafiifinta dhiigga ee warfarin.Waxaa sidoo kale loo isticmaalaa xaalado kale oo badan, laakiin ma jirto caddayn cilmiya oo wanaagsan oo lagu taageerayo inta badan isticmaalladan kale.

Daawooyinka Dabiiciga ah ee Xogta Dhamaystiran waxay qiimeysaa waxtarka ku saleysan caddeynta sayniska iyadoo loo eegayo cabirka soo socda: Wax ku ool ah, Suurta gal ah inuu wax ku ool yahay, suurtagal tahay wax ku ool ah, macquul ahaan waxtar la'aan, suurtagal ahaan waxtar la'aan, waxtar la'aan, iyo caddayn ku filan oo lagu qiimeeyo.

Qiimeynta waxtarka ee VITAMIN K waa sida soo socota:


Waxtar u leh ...

  • Dhibaatooyinka dhiig-baxa ee dhallaanka cusub ee leh heerarka fiitamiin K ee hooseeya (cudurka dhiig-baxa). Fiitamiin K1 oo afka lagaa siiyo ama muruq ahaan tallaal ahaan ayaa ka caawisa ka hortagga dhibaatooyinka dhiig baxa ee dhallaanka cusub. Xabadu waxay umuuqataa inay sida ugufiican u shaqeyso
  • Heerarka hoose ee borotiinka dhiig xinjirowga prothrombin (hypoprothrombinemia). Qaadashada fitamiin K1 afka ama irbad ahaan xididka ayaa kahortagi karta isla markaana daweyn karta dhibaatooyinka dhiigbaxa ee dadka qaba heerarka hoose ee prothrombin sababo la xiriira isticmaalka daawooyinka qaarkood.
  • Dhif dhif ah, dhiigbax la iska dhaxlo (fitamiin K ku tiirsan xinjirowga xinjirowga oo yaraada ama VKCFD). Qaadashada fitamiin K afka ama cirbad ahaan xididka ayaa kaa caawin karta kahortaga dhiig baxa dadka qaba VKCFD.
  • Ka noqoshada saameynta khafiifka dhiigga ee warfarin. Qaadashada fitamiin K1 afka ama sida duritaanka xididka ayaa wax ka bedeli karta dhiig yaraanta badan ee ay keento warfarin. Hase yeeshe, ku durista fiitamiin K1 maqaarka hoostiisa uma muuqato inuu shaqeynayo. Qaadashada fitamiin K iyo warfarin sidoo kale waxay umuuqataa inay caawineyso xasilinta waqtiga xinjirowga dhiigga dadka qaata warfarin. Waxay ugu shaqeysaa dadka leh heerarka fitamiin K-ga oo hooseeya.

Suurtagal inay wax ku ool u tahay ...

  • Lafaha oo daciifa oo jajaba (lafo xanuun). Qaadashada nooc gaar ah oo fiitamiin K2 ah waxay umuuqataa inay hagaajineyso xoogga lafaha waxayna yareyneysaa halista jabka ku dhaca dumarka da'da weyn ee leh lafaha daciifka ah. Laakiin uma muuqato inay ka faa’iideysaneyso haweenka da'da ah ee weli leh lafo adag. Qaadashada fitamiin K1 waxay umuuqataa inay kordhinayso awooda lafaha waxaana laga yaabaa inay kahortagto jabka haweenka waaweyn. Laakiin waxaa laga yaabaa inaysan si fiican ugu shaqeyn ragga waaweyn. Faytamiin K1 uma muuqdo inuu hagaajinayo awoodda lafaha haweenka aan soo marin caadada ama dadka qaba cudurka Crohn.

Suurtagal ma ahan waxtar ...

  • Dhiigbax ku dhaca ama hareeraha meelaha dareeraha ka buuxo (ventricles) ee maskaxda (dhiig-baxa intraventricular). Siinta fitamiin K haweenka halista ugu jira dhalmada kahor, uma muuqato inay ka hortageyso dhiig bax maskaxda ku dhaca dhallaanka uurka ku jira. Sidoo kale uma muuqato inay yareynayso halista dhaawaca dareemayaasha ee ay sababaan dhiigyacabkan.

Cadeymo aan ku filneyn in lagu qiimeeyo wax ku oolnimada ...

  • Waxqabadka Ciyaaraha. Daraasad hore waxay soo jeedinaysaa in qaadashada fitamiin K2 afka laga yaabo inay wanaajiso waxqabadka jimicsiga iyadoo la kordhinayo shaqada wadnaha.
  • Cilad dhiig oo yareysa heerarka borotiinka ee dhiigga loo yaqaan hemoglobin (beta-thalassaemia). Daraasad hore waxay muujineysaa in qaadashada fitamiin K2 afka oo ay weheliso kaalshiyam iyo fitamiin D ay hagaajin karto cufnaanta lafaha carruurta ee leh cilladan dhiigga.
  • Kansarka naasaha. Cilmi baaris ayaa soo jeedinaysa in qaadashada cunnooyinka badan ee fiitamiin K2 ay xiriir la leedahay halista ugu yar ee ah inuu ku dhaco kansarka naasaha.
  • Kansarka. Cilmi baarisyada qaarkood waxay xiriir la leeyihiin cunno qaadashada badan ee fiitamiin K2, laakiin kuma xirna fiitamiin K1, iyadoo ay yaraatay halista dhimashada kansarka. Laakiin cilmi baaris kale ayaa xiriirisay cunno qaadashada badan ee fiitamiin K1, laakiin kuma xirna fitamiin K2, iyadoo ay yaraatay halista dhimashada kansarka.
  • Indho-beelka indhaha. Cilmi baarisyada qaarkood waxay xiriir la leeyihiin qaadashada cuntada sare ee fiitamiin K2 oo leh qatar yar oo ah inuu ku dhaco indhaha.
  • Kansarka mindhicirka weyn, kansarka malawadka. Daraasad hore waxay soo jeedineysaa in qaadashada cuntada sare ee fitamiin K aysan xiriir la laheyn hoos u dhigista halista kansarka xiidanka iyo malawadka.
  • Wadne xanuun. Cilmi baarista badankeedu waxay muujineysaa in qaadashada cunnooyinka badan ee fiitamiin K1 iyo K2 ay xiriir la leeyihiin yaraynta halista cudurka wadnaha. Laakiin qaadashada cuntada sare ee fiitamiin K1 uma muuqato inay yareynayso halista u dhimashada guud ahaan cudurka wadnaha.
  • Cudurka 'Cystic fibrosis'. Dadka qaba cystic fibrosis waxay leeyihiin heerar hoose oo fiitamiin K ah sababo la xiriira dhibaatooyinka dheefshiidka dufanka. Qaadashada fitamiin K waxay kordhisaa heerarka fitamiin K. Laakiin ma cadda inay ka hortageyso dhibaatooyinka xinjirowga dhiigga iyo koritaanka lafaha dadkaas.
  • Niyad jab. Daraasad hore ayaa lagu ogaaday in qaadashada badan ee fitamiin K ee cuntada ay laxirirto halista hoose ee niyadjabka. Laakiin ma jiraan wax cilmi-baaris ah oo ku saabsan haddii qaadashada fitamiin K-ga ay yareyn karto halista niyad-jabka.
  • Sonkorowga. Daraasad hore waxay muujineysaa in qaadashada fitamiin badan oo lagu xoojiyey fitamiin K1 aysan yareynin halista ah inuu ku dhaco cudurka macaanka marka la barbardhigo qaadashada fitamiinada joogtada ah.
  • Firiiric u eg finanku oo ay sababaan dawooyinka kansarka qaarkood. Dadka la siiyo nooc ka mid ah dawooyinka lidka ku ah kansarka badiyaa waxay yeeshaan finan maqaarka ah. Cilmibaaris hore waxay muujisay in la mariyo kareem ay kujirto fitamiin K1 waxay ka hortageysaa finanka maqaarka dadka la siinayo daawada noocan ah. Laakiin cilmi baaris kale ayaa muujineysa in isticmaalka boomaatada leh fitamiin K aysan kor u qaadin finankan dadka horay u soo saaray.
  • Kalastarol sare. Waxaa jira caddeyn hore in fiitamiin K2 laga yaabo inuu hoos u dhigo kolestaroolka dadka ku jira kaadi-sifeynta ee leh heerarka kolestaroolka sare.
  • Kansarka beerka. Qaadashada fitamiin K2 uma muuqato inay ka hortageyso soo noqoshada kansarka beerka. Laakiin cilmibaarista hore qaarkood waxay muujineysaa in qaadashada fitamiin K2 ay yareyneyso halista kansarka beerka ku dhaca dadka qaba cirrhosis beerka.
  • Cudurka beerka. Ku duri fiitamiin K muruqa ayaa lala xiriiriyay khatarta dhimashada ee dadka qaba beerka oo shaqeynaya.
  • Kansarka sambabka. Daraasad hore waxay soo jeedineysaa in qaadashada badan ee fitamiin K2 ee cuntada ay laxirirto hoos udhaca halista kansarka sanbabada iyo dhimashada la xiriirta kansarka sanbabada. Cunto qaadashada fiitamiin K1 uma muuqato inay xiriir la leedahay hoos u dhaca halista dhacdooyinkan.
  • Cudurka 'sclerosis' (MS). Interferon waa daawo caawisa dadka qaba MS. Dawadani waxay badanaa keentaa finan iyo gubasho maqaarka. Cilmibaaristii ugu horreysay waxay muujineysaa in codsashada kareemka fitamiin K ay si xishood leh u yareynayso finanka iyo gubashada dadka lagu daaweeyo interferon.
  • Dhimasho sabab kasta ha ahaatee. Qaadashada yar ee fiitamiin K waxay ku xirnaan kartaa halista sare ee dhimashada dadka waaweyn ee caafimaadka qaba.
  • Kansarka qanjirka 'prostate'. Daraasad hore ayaa lagu ogaaday in qaadashada cuntada sare ee fiitamiin K2, laakiin aan la helin fitamiin K1, ay la xiriirto yareynta halista kansarka qanjirka 'prostate'.
  • Rheumatoid arthritis (RA). Cilmi-baarista hore waxay muujineysaa in qaadashada fitamiin K2 oo ay weheliso daawada arthritis-ka ay yareyneyso calaamadaha bararka wadajirka ah si ka wanaagsan sida loo qaato daawada arthritis-ka oo keliya. Laakiin qaadashada fitamiin K1 uma muuqato inay yareynayso calaamadaha RA.
  • Faalig. Cilmi-baarista dadka waxay ogaatay in qaadashada cuntada ee fitamiin K1 aysan xiriir la lahayn qatarta istaroogga.
  • Nabaro.
  • Gubasho.
  • Nabarradii.
  • Xididdada caarada.
  • Calaamadaha fidinta.
  • Barar.
  • Xaaladaha kale.
Cadeymo dheeraad ah ayaa loo baahan yahay si loogu qiimeeyo fitamiin K adeegsigaan.

Faytamiin K waa fiitamiin muhiim u ah jirku u baahan yahay xinjirowga dhiigga, dhismaha lafaha, iyo habab kale oo muhiim ah.

Markii afka lagaa qaado: Labada nooc ee fiitamiin K (fiitamiin K1 iyo fitamiin K2) waa kuwa u dhow SAFE inta badan dadka marka si haboon loo qaato. Faytamiin K1 10 mg maalintii iyo fiitamiin K2 45 mg maalintii ayaa si badbaado leh loo isticmaali jiray ilaa 2 sano. Dadka badankood ma dareemaan waxyeellooyin marka ay qaadanayaan fitamiin K qaddarka lagula taliyo maalin kasta. Laakiin dadka qaar ayaa laga yaabaa inay yeeshaan calool xanuun ama shuban.

Marka la mariyo maqaarka: Vitamin K1 waa BADBAADO KU SAABSAN dadka badankood markii loo mariyo kareem ay ku jiraan 0.1% fitamiin K1.

Marka lagu siiyo IV: Labada nooc ee fiitamiin K (vitamin K1 iyo vitamin K2) waa KU SOO DHAWEYN SAFE dadka intiisa badan markii lagu mudo irbadda xididka si habboon.

Taxaddarrada gaarka ah & digniinta:

Uurka iyo nuujinta: Marka lagu qaato qadarka lagu taliyey maalin kasta, fitamiin K waa KU SOO DHAWEYN SAFE loogu talagalay haweenka uurka leh iyo kuwa nuujinaya. Ha isticmaalin qaddar badan adigoon talo bixin xirfadlahaaga daryeelka caafimaadka.

Caruurta: Nooca fitamiin K ee loo yaqaan fitamiin K1 waa KU SOO DHAWEYN SAFE loogu talagalay carruurta marka afka laga qaato ama jirka looga durayo si habboon.

Cudurka kilyaha: Fiitamiin K aad u badan ayaa waxyeello yeelan kara haddii aad qaadanaysid daaweyn sifeyn ah kelyo xanuun awgood.

Cudurka beerka: Faytamiin K waxtar uma leh daaweynta dhibaatooyinka xinjirowga ee ay keento beerka oo aad u daran. Xaqiiqdii, qiyaaso badan oo fiitamiin K ah ayaa ka dhigi kara dhibaatooyinka xinjirowga dadkaas.

Hoos udhaca dheecaanka jirka: Dadka qaba dheecaanka jirka ee yaraaday ee qaadanaya fitamiin K waxaa laga yaabaa inay u baahdaan inay qaataan cusbada dheecaanka ah ee dheecaanka leh oo ay weheliyaan fitamiin K si loo hubiyo in la qaato fiitamiin K.

Gaashaanle
Ha qaadan isku-darkaas.
Warfarin (Coumadin)
Faytamiin K ayaa jidhku u adeegsadaa inuu ka caawiyo xinjirowga dhiigga. Warfarin (Coumadin) waxaa loo isticmaalaa in lagu yareeyo xinjirowga dhiigga. Caawinta xinjirowga dhiigga, fitamiin K wuxuu yareyn karaa waxtarka warfarin. Hubso inaad si joogto ah u hubiso dhiiggaaga. Qiyaasta warfarin-kaaga ayaa laga yaabaa in loo baahdo in la beddelo.
Coenzyme Q10
Coenzyme Q10 wuxuu kiimiko ahaan la mid yahay fitamiin K iyo, sida fitamiin K, wuxuu kobcin karaa xinjirowga dhiigga. Adeegsiga labadan shey ayaa kor u qaadi kara xinjirowga dhiigga in ka badan inta la isticmaalayo hal keliya. Isku darkaan wuxuu dhibaato ku noqon karaa dadka qaata warfarin si ay u yareeyaan xinjirowga dhiigga. Coenzyme Q10 oo lagu daray fitamiin K ayaa laga yaabaa inay buuxiso saameynta warfarin waxayna u oggolaan kartaa dhiigga inuu xinjiroobo.
Tiratricol
Waxaa jira walaac ah in tiratricol laga yaabo inuu faragaliyo doorka fitamiin K ee xinjirowga dhiigga.
Fitamiin A
Xayawaanka, qaadashada sare ee fiitamiin A-ga ayaa faragalin ku sameysa fitamiin K karti xinjirowga dhiiga. Laakiin lama oga haddii tani ay sidoo kale ku dhacdo dadka.
Vitamin E
Qiyaaso badan oo fiitamiin E ah (tusaale. In kabadan 800 oo unug / maalintii) ayaa fitamiin K ka dhigi kara mid aan waxtar badan u lahayn xinjirowga dhiigga. Dadka qaadanaya warfarin si ay uga ilaaliyaan dhiigooda xinjirowga, ama dadka qaadashada yar ee fiitamiin K, qadar sare oo fitamiin E ah ayaa kordhin kara halista dhiig bax.
Dufan iyo cuntooyin dufanku ku jiro
Cunista cuntooyinka ay ku jiraan subagga ama dufanka kale ee nafaqada leh oo ay weheliso cuntooyinka fiitamiin K-ku jiro, sida isbinaajka, waxay umuuqataa inay kordhinayso qaadashada fitamiin K.
Qiyaasaha soo socda ayaa lagu bartay cilmi baarista sayniska:

DADKA WAAWEYN

AFKA:
  • Lafaha daciifka ah iyo jaban (lafo-beelka): Foomka MK-4 ee fiitamiin K2 ayaa lagu qaatay qiyaas dhan 45 mg maalin kasta. Sidoo kale, fiitamiin K1 ayaa lagu qaatay qiyaas ah 1-10 mg maalintii.
  • Dhif dhif ah, dhiigbax la iska dhaxlo (fitamiin K ku tiirsan xinjirowga xinjirowga ama VKCFD): 10 mg oo fitamiin K ah ayaa la qaatay 2-3 jeer usbuucii.
  • U noqoshada waxyeelada dhiiga khafiifinta ee warfarin: Hal qiyaas oo ah 1-5 mg oo fitamiin K1 ah ayaa caadi ahaan loo isticmaalaa in lagu beddelo saameynta qaadashada warfarin aad u badan. Qiyaasta saxda ah ee loo baahan yahay waxaa go'aamiya baaritaanka shaybaarka ee loo yaqaan INR. Qiyaasta maalinlaha ah ee 100-200 microgram ee fitamiin K ayaa loo isticmaalay dadka qaata warfarin muddada-dheer ee xinjirowga dhiigga oo aan degganeyn.
LOO BAAHAN YAHAY:
  • Dhif dhif ah, dhiigbax la iska dhaxlo (fitamiin K-ku tiirsan xinjirowga xinjirowga ama VKCFD): 10 mg oo fitamiin K ah ayaa lagu duray xididka. Inta jeer ee cirbadahaan la bixiyo waxaa go'aamiya baaritaanka shaybaarka ee loo yaqaan INR.
  • U noqoshada waxyeelada dhiiga khafiifinta ee warfarin: Hal qiyaas oo ah 0.5-3 mg oo fiitamiin K1 ah ayaa caadi ahaan la isticmaalaa. Qiyaasta saxda ah ee loo baahan yahay waxaa go'aamiya baaritaanka shaybaarka ee loo yaqaan INR.
CARRUURTA

Afka:
  • Dhibaatooyinka dhiigbaxa ee dhallaanka cusub ee heerarkoodu hooseeyo ee fiitamiin K (cudurka dhiig baxa): 1-2 mg oo fiitamiin K1 ah ayaa lagu siiyay saddex qiyaasood oo ka badan 8 toddobaad. Sidoo kale hal qaadasho oo ka kooban 1 mg oo fiitamiin K1 ah, 5 mg oo fiitamiin K2 ah, ama 1-2 mg oo fiitamiin K3 ah ayaa la isticmaalay.
LOO BAAHAN YAHAY:
  • Dhibaatooyinka dhiigbaxa ee dhallaanka cusub ee heerarkoodu hooseeyo ee fitamiin K (cudurka dhiig baxa): 1 mg oo fiitamiin K1 ah ayaa lagu duray muruqa.
Ma jiro macluumaad cilmiyaysan oo ku filan oo lagu ogaanayo gunnooyinka lagu taliyey ee cuntada (RDAs) ee fiitamiin K ah, sidaas darteed talooyin ku filan qaadashada maalin kasta (AI) ayaa loo adeegsadaa halkii: AIsku waa: dhallaanka 0-6 bilood, 2 mcg; dhallaanka 7-12 bilood, 2.5 mcg; carruurta 1-3 sano, 30 mcg; carruurta 4-8 sano, 55 mcg; carruurta 9-13 sano, 60 mcg; qaangaarka 14-18 sano (oo ay ku jiraan kuwa uurka leh ama naas nuujinaya), 75 mcg; ragga ka weyn 19 sano, 120 mcg; haweenka ka weyn 19 sano (oo ay ku jiraan kuwa uurka leh iyo kuwa naas nuujinaya), 90 mcg.

2-methyl-1,4-naphthoquinone, 2-methyl-3-phytyl-1,4-naphthoquinone, 4-Aamino-2-Methyl-1-Naphthol, Faytamiin-Labanlaab, Menadiol, Menadiol Acetate, Menadiol Diacetate, Menadiol Sodium Diphosphate, Menadiol Sodium Phosphate, Menadiolum Solubile Methynaphthohydroquinone, Menadione, Ménadione, Menadione Sodium Bisulfite, Menaquinone, Ménaquinone, Menatetrenone, Menatétrenone, Phytonadione, Methylphytone, .

Si aad wax badan uga ogaato sida maqaalkan loo qoray, fadlan eeg Daawooyinka Dabiiciga ah ee Xogta Dhamaystiran habka.


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