Duritaanka Acid Zoledronic

Qanacsan

• Kahor intaadan helin duritaanka aashitada aashitada,
• Aaladda loo yaqaan 'Zoledronic acid' waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahan, ama kuwa ku taxan qaybaha SIDEED ama KA-QAADASHO, ay u daran yihiin ama u tegi waayaan:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba wac dhakhtarkaaga:
• Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

Aaladda loo yaqaan 'Zoledronic acid' (Reclast) waxaa loo isticmaalaa in looga hortago ama lagu daaweeyo lafo-beelka lafa-beelka 'osteoporosis' (xaalad ah in lafuhu noqdaan kuwo khafiif ah oo daciif ah oo si fudud u jaba) haweenka soo maray caadada ('isbeddelka nolosha,' dhammaadka caadada caadiga ah) Zoledronic acid (Reclast) sidoo kale waxaa loo isticmaalaa in lagu daaweeyo lafa-beelka ragga, iyo in laga hortago ama lagu daaweeyo lafo-beelka ragga iyo dumarka qaata daawada loo yaqaan 'glucocorticoids' (nooc ka mid ah dawooyinka loo yaqaan 'corticosteroid' oo keeni kara lafo-beel). Zoledronic acid (Reclast) sidoo kale waxaa loo isticmaalaa in lagu daaweeyo cudurka Paget ee lafaha (xaalad ay lafuhu jilicsan yihiin oo daciif ah oo laga yaabo inay isbadal badan yihiin, xanuun badan yihiin, ama si fudud u jaban yihiin). Aaladda loo yaqaan 'Zoledronic acid' (Zometa) ayaa loo isticmaalaa in lagu daaweeyo heerarka sare ee kaalshiyamka dhiigga ku jira ee laga yaabo inay sababaan noocyada kansarka qaarkood. Aaladda loo yaqaan 'Zoledronic acid' (Zometa) waxaa sidoo kale loo isticmaalaa daaweynta kiimikada ee kansarka si loo daweeyo dhaawaca lafaha ay keento myeloma badan [kansar ka bilaabma unugyada plasma (unugyada dhiigga cad ee soo saara walxaha loo baahan yahay si loola dagaallamo infekshinka)] ama kansar ka bilaabatay qayb kale oo ka mid ah jirka laakiin wuxuu ku faafay lafaha. Aaladda loo yaqaan 'Zoledronic acid' (Zometa) maahan kansarka kiimoteraabiga, kamana gaabin doonto ama ma joojin doonto faafitaanka kansarka. Si kastaba ha noqotee, waxaa loo isticmaali karaa in lagu daaweeyo cudurka lafaha bukaanka qaba kansarka. Aaladda loo yaqaan 'Zoledronic acid' waxay ku jirtaa nooc daawooyin ah oo loo yaqaan 'bisphosphonates'. Waxay ku shaqeysaa iyadoo hoos u dhigeysa burburka lafaha, kordhinta cufnaanta lafaha (dhumucda), iyo hoos u dhigista xaddiga kaalshiyamka ee laga sii daayo lafaha dhiigga.

Aaladda loo yaqaan 'Zoledronic acid' waxay u timaadaa xal ahaan (dareere) in lagu mudo xididka ugu yaraan 15 daqiiqo. Badanaa waxaa ku duraya bixiye daryeel caafimaad xafiiska dhakhtarka, isbitaalka, ama rugta caafimaadka. Marka cirbadda loo yaqaan 'zoledronic acid duray' loo isticmaalo in lagu daaweeyo heerarka dhiigga ee sare ee kaalshiyamka uu sababo kansarka waxaa badanaa loo qaataa hal qiyaas oo keliya. Qiyaasta labaad waxaa la siin karaa ugu yaraan 7 maalmood ka dib qiyaasta koowaad haddii kaalshiyamka dhiiggu uusan hoos ugu dhicin heerarka caadiga ah ama uusan ku sii jirin heerarka caadiga ah. Marka cirbadeynta aaladda loo yaqaan 'zoledronic acid' loo isticmaalo in lagu daaweeyo dhaawaca lafaha ay keento myeloma badan ama kansar ku faafay lafaha, badanaa waxaa la siiyaa hal mar 3dii ilaa 4tii toddobaad kasta. Marka cirbadda loo yaqaan 'zoledronic acid duray' loo isticmaalo in lagu daaweeyo lafa-beelka dumarka soo maray, ama ragga, ama lagu daaweeyo ama looga hortago lafo-beelka dadka qaata daawada loo yaqaan 'glucocorticoids', waxaa badanaa la siiyaa sanadkiiba hal mar. Marka loo isticmaalo aaladda loo yaqaan 'zoledronic acid' si looga hortago lafo-beelka dumarka soo maray caadada, waxaa badanaa la siiyaa hal mar 2-dii sanoba. Marka loo isticmaalo daawada loo yaqaan 'zoledronic acid' in lagu daaweeyo cudurka Paget ee lafaha, badanaa waxaa loo qaataa hal qiyaas oo keliya, laakiin qiyaaso dheeraad ah ayaa la bixin karaa ka dib markii muddo la soo dhaafay.

Hubso inaad ku cabto ugu yaraan 2 koob oo biyo ah ama dareere kale dhowr saacadood gudahood ka hor intaadan helin aaladda loo yaqaan 'zoledronic acid'.

Dhakhtarkaagu wuxuu kuu qori karaa ama kugula talin karaa kaalshiyam dheeri ah iyo fiitamiin fara badan oo ay ku jirto fitamiin D si aad u qaadato inta lagu jiro daaweyntaada. Waa inaad u qaadataa kaabisyadan maalin kasta sida uu takhtarku ku faro. U sheeg dhakhtarkaaga haddii ay jiraan wax sabab ah oo aanad awood u lahayn inaad qaadato waxyaalahan dheeriga ah inta lagu jiro daaweyntaada.

Waxaad dareemi kartaa fal-celin inta lagu gudajiro maalmaha ugu horeeya kadib marka aad hesho qaddarka cirbadeynta aaladda zoledronic acid. Calaamadaha falcelintan waxaa ka mid noqon kara astaamaha hargabka oo kale ah, qandho, madax xanuun, qarqaryo, iyo lafo, kalagoys ama murqo xanuun. Calaamadahaasi waxay bilaaban karaan 3-da maalmood ee ugu horeysa kadib marka aad qaadatid qaddarka cirbadeynta aaladda loo yaqaan 'zoledronic acid' waxaana laga yaabaa inay socdaan 3 illaa 14 maalmood. Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaad qaadato xanuun joojiye aan qoro / xummad yareeye kadib markaad hesho cirbadeynta aaladda loo yaqaan 'zoledronic acid' si looga hortago ama loo daaweeyo astaamahan.

Haddii aad qaadanayso cirbadeynta aaladda loo yaqaan 'zoledronic acid' si looga hortago ama loo daaweeyo lafo-beelka lafa-beelka, waa inaad sii wadataa helitaanka daawada sida jadwalka loo dhigay xitaa haddii aad caafimaad qabtid. Waa inaad kala hadashaa dhakhtarkaaga waqti ka waqti oo ku saabsan inaad weli u baahan tahay in lagaa daaweeyo daawadan iyo in kale.

Dhakhtarkaaga ama farmashiistahaaga ayaa ku siin doona warqada macluumaadka bukaanka soo saaraha (Tilmaamaha Daawada) markaad bilowdo daaweynta cirbadeynta zoledronic acid iyo markasta oo aad hesho qiyaas. Si taxaddar leh u akhri macluumaadka oo weydii dhakhtarkaaga ama farmashiistaha haddii aad wax su'aalo ah qabtid. Waxa kale oo aad booqan kartaa websaydhada Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ama websaydhka soosaaraha} si aad u hesho Hagaha Daawada.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan helin duritaanka aashitada aashitada,

• u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad xasaasiyad ku leedahay aaladda loo yaqaan 'zoledronic acid' ama daawooyin kale, ama wax ka mid ah waxyaabaha ku jira irbadda loo yaqaan 'zoledronic acid'. Weydii farmashiistahaaga ama ka hubi Hagaha Daawada liiska waxyaabaha ay ka kooban yihiin.
• waa inaad ogaataa in cirbadeynta aaladda loo yaqaan 'zoledronic acid' lagu heli karo hoosta magacyada magacyada Zometa iyo Reclast. Waa in lagugu daaweeyaa kaliya mid ka mid ah badeecadan markiiba.
• u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. U hubso inaad sheegto mid ka mid ah kuwan soo socda: aminoglycoside antibiotics sida amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Neo-Rx, Neo-Fradin), paromomycin (Humatin), streptomycin, iyo tobramycin (Tobi) , Nebcin); asbiriin iyo dawooyinka kale ee nonsteroidal anti-bararka (NSAIDs) sida ibuprofen (Advil, Motrin) iyo naproxen (Aleve, Naprosyn); daawooyinka kiimikada ee kansarka; digoxin (Lanoxin, oo ku taal Digitek); diuretics ('kaniiniyada biyaha') sida bumetanide (Bumex), ethacrynic acid (Edecrin), iyo furosemide (Lasix); iyo dawooyinka afka laga qaato sida dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), iyo prednisone (Deltasone). Daawooyin kale oo badan ayaa laga yaabaa inay la falgalaan aaladda loo yaqaan 'zoledronic acid', marka u sheeg dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
• u sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa qabtid cudur kalyaha ah ama haddii aad leedahay af qallalan, kaadi madow, dhididku kaa yaraaday, maqaarka oo qallalan, iyo calaamadaha kale ee fuuqbaxa ama aad dhawaan yeelatay shuban, matag, qandho, infekshin, dhidid badan, ama awoodin inaad cabto dareereyaal kugu filan. Dhakhtarkaagu wuu sugi doonaa ilaa intaad fuuqbax ka sii weydo ka hor intaadan ku siin irbadda aaladda loo yaqaan 'zoledronic acid' ama haddii aad qabto noocyo ka mid ah cudurka kelyaha laga yaabaa inaanay kuu qorin daaweyntan adiga. Sidoo kale u sheeg dhakhtarkaaga haddii waligaa dhiiggaagu ku yaraado heerka kaalshiyamka ah. Dhakhtarkaaga ayaa laga yaabaa inuu hubiyo heerka kalsiyum ee dhiiggaaga ka hor intaadan bilaabin daaweynta lagamana yaabo inuu kuu qoro daawadan haddii heerka uu aad u hooseeyo.
• u sheeg dhakhtarkaaga haddii laguu daweeyay aaladda loo yaqaan 'zoledronic acid' ama bisphosphonates kale (Actonel, Actonel + Ca, Aredia, Boniva, Didronel, Fosamax, Fosamax + D, Reclast, Skelid, iyo Zometa) waagii hore; haddii aad waligaa qalliin ku sameysay qanjirkaaga parathyroid (qanjirka yar ee qoorta) ama qanjirka 'thyroid' ama qalliin looga saarayo qaybo ka mid ah xiidmahaaga yar; iyo haddii aad leedahay ama aad waligaa wadnaha istaagtay (xaalad uusan wadnuhu dhiig ku filan ugu ridi karin qaybaha kale ee jirka); dhiig yari (xaalad unugyada dhiigga cas ay ku keeni kari waayaan oksijiin qaybaha kale ee jirka ah); xaalad kasta oo ka joojisa dhiiggaaga inuu si caadi ah u xinjiroobo; heerarka hoose ee kaalshiyamka, magnesium, ama potassium ku jira dhiigaaga; xaalad kasta oo ka hor istaageysa jirkaaga inuu nuugo nafaqooyinka cuntada; ama dhibaatooyinka afka, ilkaha, ama ciridka; caabuq, gaar ahaan afkaaga; neef ama xiiq, gaar ahaan haddii ay uga sii darto qaadashada asbiriin; ama parathyroid ama beer xanuun.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Waa inaad isticmaashaa hab lagu kalsoonaan karo oo ah xakameynta dhalmada si looga hortago uurka inta aad qaadaneysid aaladda loo yaqaan 'zoledronic acid'. Haddii aad uur yeelato inta aad qaadanaysid aaladda loo yaqaan 'zoledronic acid', wac dhakhtarkaaga. Aaladda loo yaqaan 'Zoledronic acid' waxay waxyeelleyn kartaa uurjiifka La hadal dhakhtarkaaga haddii aad qorsheyneyso inaad uur yeelato waqti kasta oo mustaqbalka ah maxaa yeelay aaladda zoledronic ayaa laga yaabaa inay jirkaaga ku sii jirto sannado ka dib markaad joojiso helitaanka.
• waa inaad ogaataa in cirbadeynta aaladda loo yaqaan 'zoledronic acid' ay sababi karto lafo, muruq, ama kalagoys xanuun daran. Waxaad bilaabi kartaa inaad dareento xanuunkaan maalmo gudahood bilaha kadib marka ugu horeysa ee lagugu mudo cirbadeynta aaladda zoledronic acid. In kasta oo xanuunka noocan ahi bilaaban karo ka dib markii aad qaadatay mudista aaladda loo yaqaan 'zoledronic acid' in muddo ah, waxaa muhiim u ah adiga iyo dhakhtarkaaga inaad ogaato inay sababi karto aaladda loo yaqaan 'zoledronic acid'. Wac dhakhtarkaaga isla markiiba haddii aad isku aragto xanuun daran wakhti kasta inta lagu jiro daweyntaada cirbadeynta aaladda loo yaqaan 'zoledronic acid'. Dhakhtarkaaga ayaa laga yaabaa inuu joojiyo inuu ku siiyo cirbadda loo yaqaan 'zoledronic acid' oo xanuunkaagu wuu iska tagi karaa ka dib markaad joojiso daaweynta daawadan.
• waa inaad ogaataa in acid zoledronic ay sababi karto osteonecrosis ee daanka (ONJ, xaalad daran oo lafta daanka ah), gaar ahaan haddii aad qalliin ilko ama daaweyn ah inta aad daawada isticmaaleysid. Dhakhtarka ilkaha waa inuu baaro ilkahaaga oo uu sameeyaa wixii daaweyn ah ee loo baahan yahay, oo ay ku jiraan nadiifinta, ka hor intaadan bilaabin isticmaalka zoledronic acid. Hubso inaad cadayato ilkahaaga oo aad si sax ah u nadiifiso afkaaga inta aad isticmaaleysid aaladda loo yaqaan 'zoledronic acid'. La hadal dhakhtarkaaga kahor intaadan helin daaweyn ilko inta aad isticmaaleysid dawadan.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Haddii aad seegto ballan si aad u hesho faleebada loo yaqaan 'zoledronic acid', wac dhakhtarkaaga sida ugu dhakhsaha badan ee suurtogalka ah.

Aaladda loo yaqaan 'Zoledronic acid' waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahan, ama kuwa ku taxan qaybaha SIDEED ama KA-QAADASHO, ay u daran yihiin ama u tegi waayaan:

• cuncun, casaan, xanuun, ama barar meeshii lagaa duray
• casaan, barar, cuncun, ama indho ilmo ama barar hareeraha indhaha
• calool istaag
• lallabbo
• matagid
• shuban
• calool xanuun
• cunto xumo
• miisaanka oo yaraada
• laabjeex
• nabar afka ka soo baxa
• walwal xad dhaaf ah
• kacsan
• niyad jab
• dhibaato xagga hurdada ama hurdada ah
• qandho, dhaxan, qufac, iyo calaamadaha kale ee infekshanka
• balastarro cadcad oo afka ah
• barar, casaan, cuncun, gubasho, ama cuncun siilka
• dheecaanka siilka cad
• kabuubyo ama gariir ku dhaca afka ama faraha ama suulasha
• timo lumis

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba wac dhakhtarkaaga:

• finan
• finan
• cuncun
• bararka indhaha, wajiga, dibnaha, carrabka, cunaha, gacmaha, gacmaha, cagaha, anqawyada, ama lugaha hoose
• xabeeb
• neefsashada ama wax liqidda oo ku adkaata
• xabad xanuun badan
• wadne garaac aan joogto ahayn
• murqaha murqaha, kala-baxa, ama casiraad
• nabar ama dhiig bax aan caadi ahayn
• xanjo xanuun leh ama bararsan
• dabacsanaanta ilkaha
• kabuubyo ama dareen culus oo daanka ku dhaca
• ku xanuunaya afka ama daanka oo aan bogsan

Aaladda Zoledronic waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

In lagugu daaweeyo dawada bisphosphonate sida cirbadeynta aaladda loo yaqaan 'zoledronic acid' ee lafa-beelka laf-dhabarka ayaa kordhin karta halista ah inaad jabiso laftaada (lafta) bowdada. Waxaa laga yaabaa inaad dareento caajis, xanuun xanuun miskahaaga, gumaarka, ama bowdada dhowr toddobaad ama bilo kahor intaan lafaha (jibbuhu) jabin, waxaadna ogaan kartaa in mid ama labada lafood ee bawdadaada ay jabeen inkasta oo aadan dhicin ama aadan soo arag dhaawac kale. Waa wax aan caadi ahayn lafta bawdada in ay ku jabto dadka caafimaadka qaba, laakiin dadka qaba lafa-beelka lafta waa laga yaabaa in ay jabiyaan laftan xitaa haddii aysan helin cirbadda loo yaqaan 'zoledronic acid'. Kala hadal dhakhtarkaaga halista qaadashada cirbadda loo yaqaan 'zoledronic acid'.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Dhakhtarkaaga ayaa dawadan ku kaydin doona xafiiskiisa ama xafiiskeeda oo ku siin doona adiga sida loogu baahdo.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

• qandho
• daciifnimo
• murqaha oo adkaada ama murqaha oo xanuuna
• dhakhso, garaacid, ama wadno garaac aan caadi ahayn
• dawakhaad
• dhaqdhaqaaqa indhaha oo aan la xakamayn karin
• aragti labalaab ah
• niyad jab
• socodka oo adkaada
• gariir aan la koontarooli karin qayb ka mid ah jirkaaga
• qalal
• jahwareer
• neefta oo ku qabata
• xanuun, gubasho, kabuubyo ama xoqitaan gacmaha ama cagaha
• hadalka oo adkaada
• dhib liqidda
• kaadida oo yaraatay

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa tijaabooyinka shaybaarrada qaarkood si loo hubiyo jawaabta jirkaaga ee loo yaqaan 'zoledronic acid'.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Isbadal^®
• Zometa^®