Tipranavir

Qanacsan

• Kahor qaadashada tipranavir,
• Tipranavir waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:

Tipranavir (oo lagu qaato ritonavir [Norvir]) waxay sababi kartaa dhiig bax maskaxda ku dhaca. Xaaladdan ayaa laga yaabaa inay nafta halis geliso. U sheeg dhakhtarkaaga haddii dhowaan lagugu qalay, ama haddii aad dhawaan dhaawac soo gaadhay si uun. Sidoo kale, u sheeg dhakhtarkaaga haddii aad qabto cillad dhiig-bax ah sida hemophilia (xaalad aanu dhiiggu si caadi ah u xinjiroobin). U sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad qaadanayso mid ka mid ah daawooyinka soo socda: dawooyinka xinjirowga lidka ku ah ('khafiifiyeyaasha dhiigga') sida warfarin (Coumadin, Jantoven), aspirin ama alaabooyin ay ku jiraan asbiriin, cilostazol, clopidogrel (Plavix), dipyridamole (Persantine, Aggrenox) ), eptifibatide (Integrilin), heparin, nonsteroidal anti-inflammatory drugs (ibuprofen, naproxen), prasugrel (Effient), ticlopidine, ama tirofiban (Aggrastat). Sidoo kale waa inaad u sheegtaa dhakhtarkaaga iyo farmashiistahaaga haddii aad qaadanaysid fiitamiin E, marka laga reebo qaddarka ku jira fiitamiinada caadiga ah ee maalinlaha ah. Haddii aad u baahan tahay inaad hesho daaweyn caafimaad oo deg-deg ah sabab kasta ha noqotee, iska hubi inaad u sheegto dhammaan dhakhaatiirta ku daweyneysa inaad qaadanayso daawada loo yaqaan 'tipranavir'. Isla markiiba wac dhakhtarkaaga haddii aad la kulanto nabarro ama dhiig bax aan caadi ahayn inta lagugu daweynayo tipranavir.

Tipranavir (oo lagu qaato ritonavir [Norvir]) waxay sababi kartaa dhaawac beerka ah oo nafta halis gelin kara. U sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa qabtid cagaarshow (barar beerka oo uu sababo fayras), cudur kale oo beer ah, ama haddii aad cabto ama khamri cabto. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, jooji qaadashada tipranavir oo isla markiiba wac dhakhtarkaaga: daal; daciifnimo; astaamaha hargabka oo kale; cunto xumo; lallabbo matagid; xanuun, xanuun, barar, ama dareen dhinacaaga midig ah oo ka hooseeya feerahaaga; hurdi maqaarka ama indhaha; kaadi kaadi madow (midab shaah leh); ama saxaro cirro leh.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaaga ayaa amri doona baaritaano gaar ah si loo hubiyo jawaabta jirkaaga ee trannavir.

Takhtarkaaga kala hadal halista qaadashada tipranavir.

Tipranavir waxaa loo isticmaalaa ritonavir (Norvir) iyo dawooyin kale si loogu daaweeyo infekshanka fayraska difaaca jirka ee aadanaha (HIV). Tipranavir waxay ku jirtaa nooc dawooyin ah oo loo yaqaan 'protease inhibitors'. Waxay ku shaqeysaa iyadoo la yareeyo qadarka HIV ee dhiiga ku jira. In kasta oo tipranavir uusan bogsiinaynin HIV, waxay yareyn kartaa fursaddaada inaad kuhesho cillad difaac la'aanta jirka (AIDS) iyo cudurada la xiriira HIV sida infekshannada halista ah ama kansarka. Qaadashada daawooyinkan oo ay weheliso ku-dhaqan galmo badbaado leh iyo isbeddello kale oo hab-nololeed ah ayaa yareyn kara halista u gudbinta fayraska HIV dadka kale.

Tipranavir wuxuu u yimaadaa sida kaabsol iyo xalka afka (dareeraha) ee afka lagu qaato. Haddii tipranavir lagu qaato kiniiniyada loo yaqaan 'ritonavir capsules' ama xalka, badanaa waa laba jeer maalintii cunto ama la'aan. Haddii tipranavir lagu qaato kiniiniyada ritonavir, badiyaa waa laba jeer maalintii oo la cuno. Qaado tipranavir iyo ritonavir qiyaastii isla waqtiyada maalin kasta. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado tipranavir sida saxda ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

Ha qaadan tipranavir la'aantiis ritonavir.

Kaabsoosha wada liq; ha calalin ama ha burburin. Haddii aadan awoodin inaad liqdo kaabsoosha, u sheeg dhakhtarkaaga ama farmashiistahaaga.

Tipranavir waxay caawisaa xakamaynta cudurka HIV laakiin ma daaweyso. Sii wad inaad qaadato 'tipranavir' xitaa haddii aad fiicnaan dareento. Ha u istaagin qaadashada daawada 'tipranavir' adiga oo aan la hadlin dhakhtarkaaga. Haddii aad joojiso qaadashada trannavir ama aad ka booddo qiyaasaha, xaaladdaadu way sii adkaan doontaa in la daweeyo. Marka sahaydaada tipranavir ay bilaabato inay hoos u dhacdo, wax badan ka hel dhakhtarkaaga ama farmashiistahaaga.

Weydii dhakhtarkaaga ama farmashiistaha nuqul ka mid ah macluumaadka soo saaraha ee bukaanka. Si taxaddar leh u akhri macluumaadkan oo weydii takhtarkaaga ama farmashiistaha haddii aad wax su'aalo ah qabtid.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada tipranavir,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay tipranavir, ritonavir (Norvir, Kaletra), dawooyinka sulfa, dawooyinka kale, ama mid ka mid ah maaddooyinka ku jira kaabsulka ama xalka Weydii farmashiistahaaga haddii aadan hubin in daawo aad xasaasiyad u leedahay ay tahay dawo sulfa ah. Sidoo kale, weydii farmashiistahaaga liistada waxyaabaha ku jira kaabsoosha ama xalka.
• u sheeg dhakhtarkaaga haddii aad qaadanayso mid ka mid ah daawooyinka soo socda ama dhirta ka soo baxda: alfuzosin (Uroxatral); cisapride (Propulsid) (mar dambe ma laga heli karo Mareykanka); dawooyinka ergot ee xanuunka dhanjafka sida dihydroergotamine (DHEE 45, Migranal), ergoloid mesylate (Hydergine), ergotamine (Ergomar, Cafergot, Migergot, kuwa kale), ama methylergonovine (Methergine); daawooyinka qaarkood ee garaaca wadnaha aan caadiga ahayn oo ay ku jiraan amiodarone (Nexterone, Pacerone), flecainide, propafenone (Rythmol), ama quinidine (Nuedexta); lovastatin (Altoprev), lurasidone (Latuda); midazolam afka; pimozide (Orap); rifampin (Rifadin, Rimactane, gudaha Rifamate, Rifater); sildenafil (Revatio) ee daaweynta dhiig-karka sambabada, simvastatin (Zocor, ee Vytorin); Johannesört wort; iyo triazolam (Halcion). Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaadan qaadan daawada loo yaqaan 'tipranavir' haddii aad qaadanaysid mid ama in kabadan oo daawooyinkan ah
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto dawooyinka ku taxan qaybta DIGNIIN MUHIIM AH iyo mid ka mid ah kuwan soo socda: daawooyinka antifungal sida fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Extina, Nizoral, Xolegel), ama voriconazole (Vfend); boceprevir (oo aan hadda laga helin Mareykanka; Victrelis); bosentan (Tracleer); Kaalshiyam-kanaal xirayaasha sida diltiazem (Cardizem, Cartia, Diltzac, Taztia, Tiazac, kuwa kale), felodipine, nicardipine, nisoldipine (Sular), ama verapamil (Calan, Covera, Verelan, kuwa kale); daawooyinka kalastarolka ka yareeya (‘statins’) sida atorvastatin (Lipitor, in Caduet) iyo rosuvastatin (Crestor); clarithromycin (Biaxin, gudaha Prevpac); colchicine (Colcrys, Mitigare, oo ku yaal Col-Probenecid); desipramine (Norpramin); disulfiram (Antabuse); daaweynta hormoonka estrogen; fluticasone (Flonase, Flovent, Advair, Dymista); immunosuppressants sida cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), ama tacrolimus (Astagraf, Envarsus XR, Prograf, kuwa kale); dawooyinka sonkorowga sida glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (Diabeta, Glynase, kuwa kale), pioglitazone (Actos, in Actoplus Met, in Duetact, in Oseni), repaglinide (Prandin, in Prandimet), ama tolbutamide; daawooyinka qaarkood ee cillad aan caadi ahayn oo ay ka mid yihiin sildenafil (Viagra), tadalafil (Adcirca, Cialis), ama vardenafil (Levitra, Staxyn); dawooyinka qaarkood ee suuxdinta oo ay ku jiraan carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenobarbital, phenytoin (Dilantin, Phenytek), iyo valproic acid (Depakene); daawooyinka kale ee HIV oo ay ka mid yihiin abacavir (Ziagen, Epzicom, Trizivir), atazanavir (Reyataz, in Evotaz), dolutegravir (Tivicay, in Juluca), enfuvirtide (Fuzeon); etravirine (Intelence); fosamprenavir (Lexiva), lopinavir (in Kaletra), raltegravir (Isentress), iyo saquinavir (Invirase); meperidine (Demerol); methadone (Dolophine, Methadose); metronidazole (Flagyl, gudaha Pylera); omeprazole (Prilosec, Zegerid); quetiapine (Seroquel); rifabutin (Mycobutin); salmeterol (Serevent, Advair); xakamaynta serotonin reuptake inhibitors (SSRIs) sida fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), paroxetine (Brisdelle, Paxil, Pexeva), ama sertraline (Zoloft); telaprevir (oo aan laga heli karin Maraykanka; Incivek); iyo trazodone. Daawooyin kale oo badan ayaa sidoo kale la macaamili kara tipranavir, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan. Hubso inaad la hadasho dhakhtarkaaga ama farmashiistaha intaadan bilaabin qaadashada wax daawo ah inta lagu guda jiro daaweyntaada tipranavir. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
• haddii aad qaadanayso didanosine (Videx), qaado 2 saac ka hor ama 2 saacadood ka dib markii aad qaadatid tipranavir.
• haddii aad qaadanaysid dawada asiidh-diidka ah, qaado 1 saac ka hor ama 2 saacadood ka dib markii aad qaadatid tipranavir.
• u sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa qabto sonkorow ama sonkor dhiig oo sarreeya; kolestaroolka dhiigga sareeya ama triglycerides (dufanka dhiigga); ama infekshan yimaada oo taga sida qaaxada (TB), cytomegalovirus (CMV), herpes, Mycobacterium avium, shingles, ama oofwareen.
• waa inaad ogaataa in dadka qaarkiis ee qaba sonkorowgu uu ku sii xumaado sonkorowgooda inta ay qaadanayaan tipranavir. Haddii aad qabtid sonkorow, waa muhiim inaad si taxaddar leh ula socoto sonkorta dhiiggaaga inta aad qaadanaysid 'tipranavir' una wac takhtarkaaga haddii sonkorta dhiiggaaga ay adkaato in la xakameeyo. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu badalo daawadaada sonkorowga ama uu kuu qoro daawo cusub oo lagu xakameeyo sonkorta dhiiggaaga.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanaysid daawada 'tipranavir', wac dhakhtarkaaga. Ha nuujin naaska haddii aad qabtid cudurka HIV ama aad qaadatid tipranavir.
• waa inaad ogaataa in tipranavir ay yareyn karto waxtarka uur-qaadidda ee hormoonnada (kaniiniyada ka hortagga uurka, dhejiska, giraanyada, iyo cirbadaha). Waxaad u baahan doontaa inaad isticmaasho hab kale oo ka hortagga uurka ah si aad uga hortagto uurka inta aad qaadanaysid 'tipranavir'. Kala hadal dhakhtarkaaga siyaabo kale oo looga hortago uurka inta aad qaadanaysid dawadan.
• haddii aad qalliin samaynayso, oo ay ku jiraan qalliinka ilkaha, u sheeg dhakhtarka ama dhakhtarka ilkaha inaad qaadanayso dawada loo yaqaan 'tipranavir'.
• qorsheyso inaad iska ilaaliso soo-gaadhista qorraxda aan loo baahnayn ama daba dheeraatay iyo inaad xidhato dhar ilaaliya, muraayadaha indhaha, iyo muraayadda qorraxda. Tipranavir ayaa laga yaabaa inay maqaarkaaga u nuglaato iftiinka qoraxda.
• waa inaad ogaataa in dufanka jirkaagu uu kordhin karo ama u dhaqaaqi karo meelo kala duwan oo jirkaaga ah sida dhabarka qoortaada iyo garbaha kore ('buffalo hump'), caloosha, iyo naasaha. Jirkaaga waxaa laga yaabaa inuu ka dhumo baruurta gacmaha, lugaha, wajiga, iyo badhida. La hadal dhakhtarkaaga haddii aad ku aragto mid ka mid ah isbeddelladan dufanka jidhkaaga.
• waa inaad ogaataa inaad la kulmi karto hyperglycemia (kordhinta sonkorta dhiiggaaga) inta aad qaadanaysid dawadan, xitaa haddii aadan horey u qabin cudurka macaanka. Isla markiiba u sheeg dhakhtarkaaga haddii aad isku aragto mid ka mid ah astaamahan soo socda inta aad qaadanaysid tipranavir: harraad aad u daran, kaadi badan, gaajo aad u daran, aragga oo xumaada, ama daciifnimo. Aad ayey muhiim u tahay inaad wacdid dhakhtarkaaga isla marka aad isku aragto mid ka mid ah astaamahan, maxaa yeelay sonkorta dhiigga ee sareysa ee aan la daaweyn waxay sababi kartaa xaalad halis ah oo loo yaqaan ketoacidosis. Ketoacidosis wuxuu noqon karaa mid nafta halis geliya haddii aan lagu daaweyn marxaladda hore. Calaamadaha lagu garto ketoacidosis waxaa ka mid ah afka oo qalala, lallabbo iyo matag, neefta oo ku qabata, neefta oo urta miraha, iyo miyirka oo yaraada.
• Waa inaad ogaataa inta aad qaadanaysid dawooyinka lagu daaweynayo infekshinka HIV, nidaamkaaga difaaca ayaa laga yaabaa inuu sii xoogeysto oo uu bilaabo inuu la dagaallamo infekshannada kale ee horey ugu jiray jirkaaga. Tani waxay kugu sababi kartaa inaad yeelato calaamadaha infekshannadaas. Haddii aad isku aragto astaamo cusub ama kasii daraya wakhti kasta inta lagu guda jiro daaweyntaada tipranavir, hubi inaad u sheegto dhakhtarkaaga.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Qaado qiyaasta la seegay si aad u wadaagto ritonavir isla marka aad xusuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaasta xigta, ka bood qiyaasta la seegay oo sii wad jadwalka daawadaada caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Tipranavir waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• shuban
• miisaanka oo yaraada
• madax xanuun
• calool xanuun

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo degdeg ah:

• qandho, dhaxan, qufac, ama calaamadaha kale ee infekshinka
• finan
• guduudasho, barar, ama diirka maqaarka
• cuncun
• dhuunta oo isku dhegta
• neefta oo ku qabata
• daciifnimo, kabuubyo iyo xanuun, gacmaha iyo cagaha
• neefsashada ama wax liqidda oo ku adkaata
• muruqyada ama kalagoysyada xanuunka ama qallafsanaanta

Tipranavir waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku kaydi dhalooyinka aan furmin ee kaabsoolka tipranavir qaboojiyaha. Ku kaydi dhalooyinka furan ee kaabsal tipranavir heerkulka qolka, oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha). Ku kaydi xalka tipranavir heerkulka qolka. Ha qaboojineyn ama ha qaboojin xalka tipranavir. Ku calaamadee taariikhda aad dhalada of tipranavir ku fureyso calaamadda; haddii aan daawada lagu isticmaalin 60 maalmood gudahood, iska tuur daawada haray.

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa tijaabooyinka shaybaarka qaarkood si loo hubiyo jawaabta jirkaaga ee trannavir.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Aptivus^®