Cirbadeynta Methylnaltrexone

Qanacsan

• Kahor intaadan isticmaalin cirbadeynta methylnaltrexone,
• Cirbadeynta Methylnaltrexone waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto astaamahan, jooji isticmaalka methylnaltrexone oo isla markiiba wac dhakhtarkaaga:
• Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

Cirbadeynta Methylnaltrexone waxaa loo isticmaalaa in lagu daaweeyo calool istaagga ay sababto daawooyinka xanuunka opioid (narkotikada) ee dadka qaba xanuun daba dheeraada (socda) oo aan kansar keenin laakiin laga yaabo inuu la xiriiro kansar hore ama daaweynta kansarka. Waxaa sidoo kale loo isticmaalaa in lagu daaweeyo calool istaagga ay sababaan daawooyinka xanuunka opioid ee dadka qaba jirro heer sare ah ama xanuunka kansarka firfircoon. Cirbadeynta Methylnaltrexone waxay ku jirtaa nooc ka mid ah daawooyinka loo yaqaan 'peripherally acting mu-opioid receptor antagonists'. Waxay ku shaqeysaa iyadoo laga ilaalinayo mindhicirka waxyeelada daawooyinka opioid (narcotic).

Cirbadeynta Methylnaltrexone waxay u timaaddaa sidii xal (dareere) in si subag ah loogu mudo (maqaarka hoostiisa). Markii loo isticmaalay in lagu daaweeyo calool fadhiga ay sababaan daawooyinka opioid ee dadka qaba xanuunka daba dheeraada (socda) ee uusan sababin kansarka, badanaa waxaa la isku duraa hal mar maalintii. Markii loo isticmaalay in lagu daaweeyo calool fadhiga ay sababaan daawooyinka opioid ee dadka qaba cudur daran ama kansar, waxaa badanaa lagu duraa hal mar maalin kasta sida loogu baahdo, laakiin waxaa loo isticmaali karaa ilaa hal mar 24-kii saacadoodba haddii loo baahdo. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. U isticmaal cirbadeynta methylnaltrexone sida saxda ee lagu faray. Ha u isticmaalin wax ka yar ama ka yar ama u isticmaal si ka badan inta dhakhtarku kuu qoray.

Cirbadeynta Methylnaltrexone waa inay isticmaalaan dadka qaata daawooyinka opioid (narcotic). La hadal dhakhtarkaaga haddii aad beddesho inta ama inta jeer ee aad qaadato daawooyinkaaga opioid. Haddii aad joojiso qaadashada daawooyinka opioid, waa inaad joojisaa isticmaalka daawada methylnaltrexone sidoo kale.

Waa inaad joojisaa qaadashada dawooyinka kale ee caloosha jilciya marka aad bilowdo isticmaalka cirbadeynta methylnaltrexone. Si kastaba ha noqotee, hubso inaad u sheegto dhakhtarkaaga haddii cirbadeynta methylnaltrexone aysan kuu shaqeyn doonin adiga ka dib markaad isticmaasho 3 maalmood. Dhakhtarkaagu wuxuu kuu sheegi karaa inaad qaadato daawooyinka kale (dawooyinka) caloosha jilciya.

Waad isku duri kartaa naftaada cirbadeynta methylnaltrexone ama saaxiib ama qof aad qaraabo tihiin ayaa cirbadaha ku duraya. Si taxaddar leh u akhri tilmaamaha soo-saaraha ee sharaxaya sida loo diyaariyo loona duro qiyaasta methylnaltrexone. Weydii dhakhtarkaaga ama farmashiistaha inuu ku tuso adiga ama qofka ku duraya daawada sida loo isku duro. Hubso inaad weydiiso farmasiilahaaga ama dhakhtarkaaga haddii aad wax su'aalo ah ka qabtid sida loo diyaariyo ama loo duro dawadan.

Cirbadeynta Methylnaltrexone waxay ku timaaddaa irbado horay loo soo buuxiyey iyo fijaanno si loogu isticmaalo irbado la iska tuuri karo. Weelka ayaa laga yaabaa inuu ku yimaado saxaarad leh siliinge, ama waxaad u baahan kartaa inaad si gooni ah u iibsato saliingaha. Weydii dhakhtarkaaga ama farmashiistaha haddii aad qabtid su'aalo ku saabsan nooca irbadaha la isticmaalo. Isticmaal cirbadaha horay loo soo buuxiyey, fijaannada iyo saliingaha la tuuri karo mar keliya. Tuur saliingaha la kariyey, ama fijaan iyo siliingaha hal mar kadib, xitaa haddii aysan madhanayn. Waa in lagu tuuraa weel u adkaysata daloolinta, meel aysan carruurtu gaarin. Ha ku tuurin weel daloolin leh oo buuxu u adkaysto qashinka guriga ama dib u warshadaynta. Kala hadal dhakhtarkaaga ama farmashiistaha sida loo tuuro weelka daloolka u adkaysta.

Waad ku duri kartaa methylnaltrexone maqaarka calooshaada ama bowdyahaaga. Haddii qof kale uu kugu durayo daawada, qofkaas ayaa sidoo kale ku duri kara gacantaada kore. Xulo meel cusub mar kasta oo aad isticmaasho mudista methylnaltrexone. Ha ku durin methylnaltrexone meel jilicsan, nabar, casaan, ama adag. Sidoo kale, ha isku durin meelaha leh nabarrada ama calaamadaha fiditaanka.

Dhakhtarkaaga ama farmashiistahaaga ayaa ku siin doona warqada macluumaadka bukaanka soo saaraha (Hagaha Daawada) markaad bilowdo daaweynta cirbadeynta methylnaltrexone iyo mar kasta oo aad dib u buuxiso daawadaada. Si taxaddar leh u akhri macluumaadka oo weydii dhakhtarkaaga ama farmashiistaha haddii aad wax su'aalo ah qabtid. Waxa kale oo aad booqan kartaa bogga Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) si aad u hesho Hagaha Daawada.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan isticmaalin cirbadeynta methylnaltrexone,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay methylnaltrexone, daawooyin kale, ama mid ka mid ah waxyaabaha ku jira mudista methylnaltrexone. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: alvimopan (Entereg), naldemedine (Symproic), naloxegol (Movantik), naloxone (Evzio, Narcan, in Bunavail, Suboxone, Zubsolv) ama naltrexone (Vivitrol, in Contrave, Embeda). Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
• u sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa yeelatay xannibaad caloosha ah (xannibaad ku dhaca xiidmahaaga). Dhakhtarkaagu wuxuu kuu sheegi doonaa inaadan isticmaalin mudista methylnaltrexone.
• u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa yeelatay dhibaatooyin caloosha ama mindhicirka ah oo ay ka mid yihiin nabar caloosha ah (nabarro ku dhaca dahaarka caloosha), kansarka caloosha ama mindhicirka, Crohn's disease (xaalad jirku ku weeraro dahaarka marinka dheef-shiidka. , keena xanuun, shuban, miisaanka oo hoos u dhaca, iyo qandho), diverticulitis (boorsooyin yaryar oo ku jira xuubka mindhicirka weyn oo barari kara), Ogilvie's syndrome (xaalad uu ku jiro caloosha buro ku soo baxda), ama kilyaha ama beerka cudur.
• u sheeg dhakhtarkaaga haddii aad uur leedahay ama aad qorsheyneyso inaad uur yeelato. Haddii aad uur yeelato intaad isticmaaleysid cirbadeynta methylnaltrexone, wac dhakhtarkaaga. Haddii aad hesho methylnaltrexone inta aad uurka leedahay, ilmahaaga waxaa laga yaabaa inuu la kulmo astaamaha ka bixitaanka opioid.
• u sheeg dhakhtarkaaga haddii aad naas nuujinayso. Ha nuujin naaska inta aad isticmaaleyso cirbadeynta methylnaltrexone.
• waa inaad ogaataa in dadka badankood ay saxaroonayaan daqiiqado gudahood illaa dhowr saacadood gudahood markay isticmaalaan cirbadeynta methylnaltrexone. Hubso inaad ku dhowdahay musqusha markaad isticmaaleyso daawadan.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Dad gaar ah dawadan waxaa loo isticmaalaa sidii loogu baahnaa, laakiin bukaanada kale daawadan waxaa loo isticmaalaa maalin kasta. Haddii dhakhtarkaagu kuu sheegay inaad si joogto ah u isticmaasho mudista methylnaltrexone, u isticmaal qiyaasta la seegay isla marka aad xusuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaasta xigta, ka bood qiyaasta la seegay oo sii wad jadwalka daawadaada caadiga ah. Ha u isticmaalin qaadasho laba jibbaar ah si aad u dhammaystirto mid kaa dhaafay

Cirbadeynta Methylnaltrexone waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• calool xanuun
• gaaska
• lallabbo
• matagid
• shuban
• dawakhaad
• dhidid
• qarqaryo
• walaac
• hamaansasho
• gariirid
• qabow kulul

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto astaamahan, jooji isticmaalka methylnaltrexone oo isla markiiba wac dhakhtarkaaga:

• shuban daran
• calool xanuun daran

Cirbadeynta Methylnaltrexone waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad isticmaaleyso daawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hayso kartoonka ay soo gashay, si adag u xir, oo ka fog carruurta. Ku keydi heerkulka qolka hana barafayn. Ka ilaali iftiinka. Haddii aad methylnaltrexone u soo jiido saliingaha laakiin aadan awoodin inaad isla markiiba isticmaasho, saliingaha waxaa lagu keydin karaa heerkulka qolka ilaa 24 saacadood. Saliingaha uma baahna in laga ilaaliyo iftiinka waqtigaan.

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

• dawakhaad, madax-wareer, iyo miyir beelid markaad si dhakhso leh uga kacdo booska aad jiiftay
• qarqaryo
• dhidid
• sanka oo dareera
• shuban
• calool xanuun
• walaac
• hamaansasho
• hoos udhaca saameynta xanuunka ee daawada opioid

Dhammaan ballamaha la dhig dhakhtarkaaga.

Ha u ogolaan qof kale inuu isticmaalo daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

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